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Efficacy of Tenofovir Plus Lamivudine Combination Therapy Versus Tenofovir Monotherapy for Lamivudine-resistant Chronic Hepatitis B Patients with Suboptimal Virological Suppression by Lamivudine and Adefovir
In borohydride-protected nanosilvers in laponite sol, the silver particles aggregate to form short chains and a dumbbell shape. The 1H NMR measurements in this study represent, to our knowledge, the first observation of proton resonances of borohydride-protected nanosilvers in aqueous solution. Borohydride on nanosilver can be exchanged with 11-mercaptoundecanoic acid (MUA) or trioctylphosphine (TOP). Transmission electron microscopy and UV-Vis spectroscopy data show that the number of aggregated silver nanoparticles decreases upon addition of aforementioned ligands due to the formation of silver MPCs (monolayer-protected clusters). Adsorption of MUA or TOP on nanosilver is confirmed through the observation of broad proton resonances of MPCs in 1H NMR spectra.
Evidence for the existence of a strange nonchaotic attractor (SNA) in a two-frequency quasiperiodically driven Izhikevich neuron model is presented. In this study, we found that the SNA is formed by a Heagy-Hammel mechanism because the SNA arises as Poincare sections of a period-doubled torus attractor collides with its unstable parent. Analyses of the fractal dimension, autocorrelation function, power spectral density, power spectral distribution function and interspike interval distribution function also support the existence of the SNA.
With further advances in intelligent vehicles today, the world welcomes the development of the Automatic Intelligent Cruise Control (AICC) and the self-driving car. However, these intelligent vehicles have many limitations in real environment. To address these problems, we developed methods of Vehicle Teleoperation. Using 3D maps, people could understand advance the surroundings and road conditions in advance. Furthermore, environmental data gathered from prior research groundwork is used to create waypoints, which are then transmitted wirelessly to the vehicle's computer system to enable autonomous driving. Two methods are used to create waypoints. One, for instance, is to auto-generated by time; and another, is directly generated by humans. For this, we applied two algorithms and performed simulation tests. Based on the simulation results, the two algorithms suggested effectively solved the time delay problem that causes difficulties in vehicle control. It was also demonstrated to control the vehicle even without being loaded with surrounding map data.
Objectives: The aim of this study was to examine the association between shift work and hyperuricemia among steel company workers. Methods: We examined 1,029 male workers at a Korean steel company between June 6 and June 28, 2013. We conducted anthropometric measurements, questionnaire surveys, and blood tests. Hyperuricemia was defined as a serum uric acid concentration of ≥7.0 mg/dL. Logistic regression analyses were performed. In the full model, analysis was adjusted for covariates including age, body mass index, lifestyle factors, and comorbidities. The odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for all models. Results: The participants included 276 daytime workers and 753 shift workers. Among daytime workers, 72 (26.1%) individuals had hyperuricemia, as did 282 (37.5%) individuals among shift workers (p <0.001). There was a statistically significant association between shift work and hyperuricemia. In the unadjusted model, the OR of shift work was 1.70 (95% CI 1.25-2.31) for hyperuricemia. In the full model, the OR of shift work was also statistically significant after adjustment for covariates (OR 1.41, 95% CI 1.02-1.96). Conclusions: Among male steel workers, a significant association between shift work and hyperuricemia was observed.