식도 내 이소성 피지선 1예

김선문,임의혁,정승현,이태희,허규찬,이정의,김윤미,최용우,강영우 대한소화기내시경학회 2005 Clinical Endoscopy Vol.31 No.5

Ectopic sebaceous glands have been reported in the organs of an ectodermal origin such as the oral cavity, genitals, eye and orbit, nipples, palm and soles, and the parotid glands. Their presence in the esophagus, which is an organ of endodermal origin, is a very rare and interesting anomaly. Whether ectopic sebaceous glands in the esophagus are the result of congenital misplacement or acquired metaplastic change remains unclear. We report here on a patient with sebaceous glands in the esophagus, and this was diagnosed by endoscopic biopsy. 이소성 피지선은 주로 외배엽기원인 구강, 생식기, 눈과 안와, 유두, 손바닥, 발바닥과 이하선 등에서 발생하고 내배엽 기원인 식도에서는 드물게 보고되고 있으며 우리나라에서는 1예가 보고되어 있다. 저자들은 심와부 통증을 주소로 내원한 54세 남자의 상부위장관내시경 검사에서 식도에 다수의 황색조의 융기성 병변이 있어 황색종 추정진단하에 생검을 시행하였으며, 조직검사에서 이소성 피지선으로 진단한 1예를 문헌고찰과 함께 보고한다.

뜨거운 계란찜을 먹은 후에 발생한 식도궤양 1예

김선문,정승현,김용문,구훈섭,이태희,임의혁,허규찬,김범경,최용우,강영우 대한소화기내시경학회 2006 Clinical Endoscopy Vol.32 No.3

The common causes of esophageal ulcers include severe reflux esophagitis, carcinomas, pill-induced esophagitis, viral diseases, caustic injury, foreign bodies and radiation injury. In rare cases, they can also be caused by Crohn's disease, Behcet's disease, syphilis and idiopathic causes. A thermal injury caused by the ingestion of hot food has not been reported to be a cause of esophageal ulcers. We report an alcoholic who developed an esophageal ulcer and odynophagia after ingesting part of an extremely hot steamed egg with a review of the few available reports regarding such injuries. We suggest that the ingestion of extremely hot food should also be considered a cause of esophageal ulcers. (Korean J Gastrointest Endosc 2006;32:190- 193) 식도궤양의 원인은 다양하며 심한 역류성 식도염, 식도암, 약제 유발성 식도염, 바이러스성 식도염, 부식성 손상, 식도 내 이물질에 의한 손상과 방사선 손상 등이 있다. 드물게는 크론병, 베체트병, 매독에 의한 경우도 있으나 뜨거운 음식에 의한 열손상은 식도궤양의 원인으로 보고되지 않았다. 저자들은 56세 남자가 만취상태에서 뜨거운 계란찜을 먹은 후에 흉통과 연하시 불편감을 주소로 내원하여 시행한 상부위장관내시경 검사에서 식도에 궤양이 있어 보존요법 후에 호전된 1예를 경험하여 문헌고찰과 함께 보고한다.

지방공기업 부채감축제도 도입이 지방공기업 부채비율에 미치는 영향에 관한 연구: 도시개발공사 및 기타 공사를 중심으로

김선문,정창훈 한국비교정부학회 2022 한국비교정부학보 Vol.26 No.3

(Purpose) This study empirically analyzes on how the Park Geun Hye government's introduction of the debt reduction policy for local public enterprises affected the debt of local public enterprises (Urban Development Cooperation, Other Urban Cooperations). In the process of overcoming the global financial crisis in 2009, the size of debt of affiliated public enterprises established and operated by local governments soared, and the government implemented a debt reduction policy for public enterprises to improve the financial soundness of local governments. (Design/methodology/approach) In order to analyze the effect of this debt reduction policy, the settlement data and management performance data of local public enterprises from 2011 to 2020 (panel data) were analyzed, and the results are as follows. (Findings) First, it was found that the government's implementation of the debt reduction system for local public enterprises had a negative (-) effect on the overall debt ratio. Second, it was found that the government's implementation of the debt reduction system for local public enterprises had a negative (-) effect on the current debt ratio. Finally, it was found that the non-current debt ratio did not have a statistically significant effect. (Research implications or Originality) In conclusion, it appears that the overall debt ratio and current debt ratio had been reduced due to the implementation of the debt reduction policy. However, this is because Park Geun Hye government's debt reduction policy was oriented to the debt ratio (debt/capital) reduction, not deb size itself. This study is meaningful in that it was the first empirical analysis of the effect on the debt ratio for local public enterprises since the government's debt reduction policy was implemented.

특집 - 건축과 윤리 : 출판계에서 본 건축계의 오늘과 내일 ( Today and Tomorrow of the Architectural World Looked in the Publishing World )

김선문 대한건축학회 1995 建築 Vol.39 No.2

21세기의 무한경쟁의 시대에서 우리가 해야 할 일은 철저하게 기초체력을 다져야 하는 일이다. 특히 전문분야의 세계적 경쟁이 더욱 치열해지면서 이러한 경쟁에서 이기기 위한 개인, 조직, 기업의 전문화, 차별화전략을 적극적으로 펴나가야 한다. 이러한 세계적 변화 속에서 우리 건축계와 건축출판계가 걷고 있는 현실을 정확히 보고 더이상 비난을 위한 비난이나 감정을 앞세운 상대방 깍아내리기 운동은 그만하고 서로를 밀어주어야 할 때이다.

Acute Renal Failure Following Off-pumpCoronary Artery Bypass Surgery (OPCAB) :Incidence, Risk Factors, and Outcomes

김선문,장혜련,차란희,김연수,안규리,한진석,김성권,이정상,김기봉,주권욱 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.4

Purpose : Off-pump coronary artery bypass (OPCAB) is known to be associated with a lower risk of acute renal failure (ARF) than on-pump method. However, little data is available on ARF in OPCAB. The aim of the present study was to identify the incidence, risk factors, and mortality of ARF in OPCAB. Methods : Perioperative variables in medical records of 573 patients who had undergone OPCAB from Jan 2000 to June 2004 were evaluated. ARF was defined as a 50% increase in preoperative serum creatinine (over 1.4 mg/dL) within 72 hours after operation, or as the need for postoperative dialysis. Results : The incidence of ARF and ARF requiring dialysis were 9.8% and 2.6%, respectively. The independent risk factors for ARF after OPCAB were the perioperative use of an intra-aortic balloon pump (OR, 4.425; 95% CI, 2.342-8.403), high preoperative serum creatinine (OR 2.099; 95% CI, 1.422-3.098), diabetes (OR, 1.961; 95% CI, 1.078-3.571), and old age (OR, 1.479; 95% CI, 1.034- 2.116). The in-hospital mortality rate was 53.3% for patients requiring dialysis, 19.6% for all ARF patients and 0.8% for patients without ARF (p<0.001). The 3-year cumulative mortality rate was 38.4 % in all ARF patients and 5.2% in patients without ARF (p<0.001). Conclusion : ARF was not an uncommon complication in adults who underwent OPCAB. Perioperative hemodynamic instability, preoperative renal dysfunction, diabetes, and age could independently predict the development of ARF after OPCAB and the severity of ARF was related to higher in-hospital and long-term mortality rates. Purpose : Off-pump coronary artery bypass (OPCAB) is known to be associated with a lower risk of acute renal failure (ARF) than on-pump method. However, little data is available on ARF in OPCAB. The aim of the present study was to identify the incidence, risk factors, and mortality of ARF in OPCAB. Methods : Perioperative variables in medical records of 573 patients who had undergone OPCAB from Jan 2000 to June 2004 were evaluated. ARF was defined as a 50% increase in preoperative serum creatinine (over 1.4 mg/dL) within 72 hours after operation, or as the need for postoperative dialysis. Results : The incidence of ARF and ARF requiring dialysis were 9.8% and 2.6%, respectively. The independent risk factors for ARF after OPCAB were the perioperative use of an intra-aortic balloon pump (OR, 4.425; 95% CI, 2.342-8.403), high preoperative serum creatinine (OR 2.099; 95% CI, 1.422-3.098), diabetes (OR, 1.961; 95% CI, 1.078-3.571), and old age (OR, 1.479; 95% CI, 1.034- 2.116). The in-hospital mortality rate was 53.3% for patients requiring dialysis, 19.6% for all ARF patients and 0.8% for patients without ARF (p<0.001). The 3-year cumulative mortality rate was 38.4 % in all ARF patients and 5.2% in patients without ARF (p<0.001). Conclusion : ARF was not an uncommon complication in adults who underwent OPCAB. Perioperative hemodynamic instability, preoperative renal dysfunction, diabetes, and age could independently predict the development of ARF after OPCAB and the severity of ARF was related to higher in-hospital and long-term mortality rates.

DPF장착에 따른 PM 성분별 배출특성에 관한 연구

김선문,김대욱,엄동섭,김현근,전상우,류정호,이우근 한국대기환경학회 2008 한국대기환경학회 학술대회논문집 Vol.- No.-

장중첩증으로 내원한 고립성 회장 신경섬유종 1예

김선문,이태희,임의혁,허규찬,강영우,김범경,최용우 대한내과학회 2005 대한내과학회지 Vol.69 No.5S

Pseudostenosis at the Origin of the Vertebral Artery on Contrast-enhanced MRA: Correlation with Aortic Motion on Dynamic 3D Time-Resolved Contrast-Enhanced MRA

김선문,이승원,최현석,정소령,안국진,김범수 대한자기공명의과학회 2012 Investigative Magnetic Resonance Imaging Vol.16 No.3

Purpose : The origin of the vertebral artery (VA) is a frequent site of pseudostenosis on contrast-enhanced MRA (CEMRA). The purpose of this study is to evaluate the relationship between the motion of the aortic arch and pseudostenosis at the origin of the VA. Materials and Methods: Our study had approval of our institutional review board. 47 patients underwent CT angiography (CTA), CE-MRA, and 3D time-resolved contrast-enhanced MRA (TR-CEMRA) within 6.87±9.89 days (mean±SD). Percent stenosis using the NASCET criteria was measured on CTA and CE-MRA. CTA was used as a reference standard to classify the CE-MRA into pseudostenosis and control group. Pseudostenosis was determined as 50%-99% stenosis observed on CE-MRA but normal to less than 50% stenosis on CTA. Aortic motion (distance between the highest position and lowest position of aortic arch) was measured on TR-CEMRA. Age, route of intravenous contrast media, motion of aortic arch, and normal distal diameter of VA were compared between the two groups. Results: There were 17 patients and 23 vertebral arteries of pseudostenosis. Patients with pseudostenosis showed more aortic motion (3.61±1.88 vs. 2.05±1.97 mm) and older age (71.29±8.88 vs. 62.32±13.19 year-old). Route of intravenous contrast media and normal distal diameter of VA were not associated with pseudostenosis. Conclusion: VA origin is a frequent site of pseudostenosis. Older age and more motion of aortic arch are associated with pseudostenosis on CE-MRA.

Influence of Hypertonicity on the Phenotype and Function of Bone Marrow-Derived Dendritic Cells

김선문,양승희,김연수 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.4

Purpose: Dendritic cells (DCs) are considered the most professional antigen-presenting cells (APCs) because of their unique role in initiating immunity against threatening antigens. Recently, hypertonicity has been suggested to be involved in the activation and development of immune cells such as T cells. And tonicity enhancer binding protein (TonEBP) has been thought to play a pivotal role in this process. Here, we studied the maturation status of DCs and expression of TonEBP in DCs exposed to hypertonic condition. Methods: Murine bone marrow-derived DCs were generated in the presence of GM-CSF for 6 days, and then exposed to hypertonic media. We evaluated the functional capacities and maturation of DCs using flow cytometry, mixed lymphocyte reaction, and cytokine analysis. Also we investigated the expression of TonEBP in DCs cultured in variable hypertonic media. Results: Mild hypertonicity made CD11c+ DCs to have up-regulation of CD40, 80, and 86. DCs exposed to 320 mOsm/kg media stimulated allogeneic T cell proliferation most effectively compared to DCs exposed to other tonic conditions. However, DCs exposed to 400 mOsm/kg media showed similar stimulatory capacities to isotonic control. Consistent with the phenotype changes, IL-1, 6, and TNF-α secretion increased in CD11c+ DCs exposed to mild hypertonic condition. Though we confirmed that TonEBP was expressed in CD11c+ DCs, the amount of upregulation was not dependent on the degree of hypertonicity. Conclusion: Our results suggest that hypertonicity enhances the maturation and activation of DCs.

Clinicopathologic Characteristics of IgA Nephropathy with Steroid-responsive Nephrotic Syndrome

김선문,문경철,오국환,주권욱,김연수,안규리,한진석,김성권 대한의학회 2009 Journal of Korean medical science Vol.24 No.-

Nephrotic syndrome is an unusual manifestation of IgA Nephropathy (IgAN). Some cases respond to steroid treatment. Here we describe a case-series of IgAN patients with steroid-responsive nephrotic syndrome. Twelve patients with IgAN with steroidresponsive nephrotic syndrome were evaluated and followed up. All patients presented with generalized edema. Renal insufficiency was found in two patients. The renal biopsy of eight patients revealed wide foot process effacement in addition to the typical features of IgAN. They showed complete remission after steroid therapy. Seven relapses were reported in five patients; six of the relapsed cases responded to steroid therapy. Compared with steroid-non-responsive patients, the patients with steroid-responsive nephrotic syndrome had shorter symptom duration, more weight gain, more proteinuria, and lower histologic grade than did those that had steroid-non-responsive nephrotic syndrome at presentation. None of the responders progressed to end stage renal disease, whereas five (38%) non-responders required dialysis or renal transplantation. Patients with IgAN who have steroid-responsive nephrotic syndrome likely have both minimal change disease and IgAN. The clinical features of sudden onset of generalized edema, initial heavy proteinuria and initial severe hypoalbuminemia might help identify the subset of patients, especially in low grade IgAN.