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연성 섬유종 모양의 축전다지증 ( Preaxial polydactyly )
조흔정,김동건,방동식 ( Heun Jung Cho,Dong Kun Kim,Dong Sik Bang ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
Polydactyly is the most common congenital anomaly of the upper limb. Polydactyly is classified as preaxial polydactyly(thumb), central polydactyly(index, middle and ring fingers), and postaxial polydactyly(little finger) by the site of the extra digit. A 3-day-old female newborn had a 1.5 * 1.0cm sized flesh color ed pedunculated sac like mass on the proximal phalanx of her right thumb since birth. A roentgenogram on the hand revealed no bony abnormalities of the digit and the mass contained no bony structures. The stalk of the mass was cut by the CO2 laser. On histopathological examination, a cartilage structure was found in the loosely arranged, edematous dermis and the overlying epidermis was flattened. The clinical and histological findings support the diagnosis of preaxial polydactyly. We report this interesting case of preaxial polydactyly with a review of the literature. (Kor J Dermatol 1997;35(2): 379-382)
만성 광선 피부염에서 Cyclosporine 치료의 효과 및 의의
조흔정,한승경,신항계,박윤기,이광훈 ( Heun Jung Cho,Seung Kyung Hann,Hang Kye Shin,Yoon Kee Park,Kwang Hoon Lee ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3
Background: Chronic actinic dermatitis comprises a spectrum of chronic photosensitivity disorders. Treatment includes avoidance of UV light, application of broad-spectrum topical sunscreens, PUVA therapy, corticosteroid, azathioprine and cyclosporine. Objective : Our purpose was to determine the efficacy of cyclosporine in the treatment of chronic actinic dermatitis. Methods : Six patients with chronic actinic dermatitis refractory to conventional treatment were treated with cyclosporine 100-200mg a day for four to eighteen weeks. Results . In all six patients improvement of the skin lesions and itching were dramatic, but in three of them hyperterision developed during the cyclosporine treatment. After stopping the cyclosporine therapy, their blood pressures normalized within two to five weeks. Other side effects of cyclosporine were not found. Although the skin lesions of all of the six patients were aggravated more or less after stopping the cyclosporine therapy, we could maintain their improved states with topical corticosteroids and oral antihistamines. Conclusion 1. Cyclosporine is a good alternative in treating chronic actinic dermatitis patients who are suffering from severe symptoms refractory to conventional therapy. 2. Hypertension is the frequent side effect of cyclosporine. (Kor J Dermatol 1997;36(3): 458-464)