만성 승모판 패쇄부전증 환자에서의 안지오텐신 전환효소 억제제의 장기 투여 효과

김대희,이명묵,이해영,조현재,박승정,서재빈,서정원,양한모,윤창환,조상호,이준희,김용진,김명아,손대원,오병희,박영배 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

A Study on Effect of the Elderly s Leisure Life upon Psychological Loneliness and Life Satisfaction and Social Support s Mediating Effect

Jung,Myung-Hee,Kim,Hong-Sun 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

This study, it is intended to obtain a theoretical understanding on the relationship among the elderly s leisure activity, social support, life satisfaction and mental loneliness while, together with this, it is also intended to draw policy implications for enhancing the psychological well-being of the elderly in a practical dimension. The objective of this study consists in doing research on the influence of leisure activity exerted upon both life satisfaction and mental loneliness of the elderly over 60 and also on the moderating role of social support. The purpose of this study was to search for the influence of leisure activity and social support being exerted upon life satisfaction and mental loneliness as well as the moderating role of social support. In this study, as leisure activities, the 2 types of productive leisure activity and consumptive leisure activity, and as social support, the 3 types of spouse support, children support and friend support, and the 2 factors of life satisfaction and mental loneliness have been reviewed. The result of this study is suggesting policy implications that are important for enhancing life satisfaction in senescent period of the elderly.

장묘제도의 현황 인식과 발전을 위한 실천적 방안

정민자,김명희 울산대학교 2001 생활과학논문집 Vol.3 No.1

본 논고에서는 우선 장묘 제도의 현황 및 변화 양상, 의식의 변화를 먼저 살펴보고 그에 따른 실천적 방안에 대해 논의하고자한다. 특히 앞서 가고 있는 서울특별시의 모범 사례와 지방행정에서도 모범을 보이고 있는 사업들을 소개하면서, 울산광역시의 장묘 제도의 실천적 방안에 대해서도 제언하고자 한다. 본 연구를 통하여 다음과 같은 인식과 앞으로의 과제를 제시한다. 첫째, 매장중심의 관행은 전통적 관행이라 볼 수 없으며 장묘관행은 사회현실에 따라 응통성 있게 변화해야 한다. 둘째, 종교와 묘지 관행은 깊은 관련을 가지고 있으며 종교단체의 역할이 크다고 볼 수 있다. 셋째, 장묘관련 법률의 시행과 함께 자치단체장의 관심과 준비가 함께 이루어져야 한다. 넷째, 화장률은 증가하고 있기 때문에 충분한 장묘시설의 확보가 필요하다. 다섯째, 선진국의 장묘관행을 통해 자연환경관리와 삶과 죽음의 조화를 이를 수 있는 방안을 마련해야 한다. This paper reviewed current situation and consciousness change of burial and cremation system. Also we describes practicing method on the basis of the questions. we suggested the burial and cremation plan of 7san City through introducing of the way for advance of burial and cremation. The results of this study are as follows; First, the present thinking about burial grounds is not traditional thinking and create serious problems. Therefore, thinking about burial should be changed by current situation. Second, each religion has been the important factor in determining burial and cremation culture. Also, role of religion unit is important factor. Third, practicing the law about the burial and funeral, local president keep on making an effort and preparation to improve the funeral system. Forth, because people prefer cremation when they die, the provision of cremtoria and service facilities should be expended. Fifth, the burial culture of advanced nations conserves the natural environment by promoting cemetries for people who feel that practice is not culturally unacceptable.

Model for Boundary Variation Using Fuzzy Approach

정명희 안양대학교 산업기술연구소 2000 自然科學硏究 Vol.7 No.-

It is difficult to identify exact boundaries and analyze variation around boundaries in scene images since each observation is the integrated response from some region of the earth's surface. The fuzzy approach allows the possibility of partial membership as a measure of the extent to which a pixel is associated with all the classes in mixed, uncertain situations. Since the regions are usually relatively large compared to the pixel size, interior regions far from boundaries are considered as pure regions with their own features which are not corrupted by other region type. A multiresolution data structure was integrated with this fuzzy approach for modeling boundary variation in order to efficiently implement the idea that interior regions have their own statistical featrues and boundary regions are affected by adjoining regions of different class types.

Candesartan과 Lercanidipine의 병용투여에 의한 혈압 하강 상승효과

한주희,이정진,김요한,명창선 충남대학교 약학대학 의약품개발연구소 2011 藥學論文集 Vol.26 No.-

SELDI-TOF MS를 이용한 유방암 환자 진단을 위한 새로운 혈청 표지자의 개발

정용식,김호승,윤태일,전미선,윤용달,이용성,이기환,김혜진,김명욱,박희붕 한국유방암학회 2004 한국유방암학회지 Vol.7 No.1

정주생활권 설정과 신도시 계획을 위한 연구(Ⅰ) : 정주생활권 설정을 중심으로 Focused on the establishment of residing life zone

정영동,정명희 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.1

The development of residing life zone has the basic unit of residing life zone which combines the central cities in rural area including small and middle cities and up-level towns with the areas at the back of them as one life zone. Therefore, it employs the development method on the premise of a new outlook on the region and also means the conversion into the synthetism method of central-back areas from the separatism of urban-rural areas. This study analyzes the real settlement system with the case of Yongam-gun. To establish Yongam-gun into a purposeful settlement zone, the function of central city should be strengthened, the ubran infrastructures should be expanded and the region of county(Gun) should be divided into several sub-zones of settlement for the functional connection between central cities and surrounding areas at the back of them. In addition, the purposefulness of county settlement zone and settlement sub-zones is developed hierarchically, but the settlement sub-zones must consider the purposefulness of all functions required for daily life, it should be divided within 20 min distance for access and it is analyzed that the demand of basic daily goods and services can be met at settlement sub-zones.

Effect of Psychological Well-Being on Life Satisfaction: Mediation Effects of Job Burden & Family Burden and Moderation of Employment Instability

Jung,Myung-Hee 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

The purpose of the study is to investigate the elderly s date by elderly s experience and others and to examine effects of the elderly s date upon psychological loneliness and happiness by experimental methodologies. The study investigated welfare approach to psychological loneliness and happiness at old age according to social welfare practice. The study investigated effect of the elderly s date upon psychological loneliness and happiness, and existence, degree, needs and friendliness of the date, and mediation between psychological loneliness, date and happiness, and between psychological loneness and happiness, and the problems of the elderly s date, and to suggest political ways.