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체외수정 - 배아이식 시술후 발생한 양측 난관임신 1 예
김희철,김희철(Hee Chul Kim),최범채(Bum Chae Choi),이재훈(Jae Hoon Lee),양광문(Kwang Moon Yang),홍수정(Soo Jung Hong),김혜선(Hye Sun Kim),김석훈(Seog Hun Kim),김창헌(Chang Heon Kim),강인수(Inn Soo Kang) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.4
Over the last 20 years, the frequency of multiple pregnancy has increased mainly because of the introduction of exogenous pituitary gonadotropins in the treatment of infertility. Since the advent of assisted reproductive technology, the concern about ectopic implantation of embryos has increased dramatically and it continues to be a major complication of in vitro fertilization and embryo transfer (IVF-ET). Bilateral tubal pregnancy is the least common type of ectopic implantation of two embryos. Of all extrauterine pregnancies, 1:725∼1:1580 are bilateral1,2. Simultaneous tubal pregnancies have been reported in natural cycles, recently, after ovulation induction, in-vitro fertilization2,3. The high incidence of ectopic pregnancy associated with IVF-ET continues to be a problem and frequencies of between 2.4 and 12.4% have been only a few reports of simultaneous bilateral tubal pregnancies following IVF-ET4. This paper describes a case of a simultaneous bilateral tubal pregnancy after IVF-ET in a 33 year old patient. The diagnosis was confirmed by diagnostic laparoscopy performed 25 days after embryo transfer(sixth week of gestation), which revealed bilateral tubal pregnancy. Bilateral salpingectomy was performed. With a review of the literature on this topic, diagnostic aspects and treatment options are discussed.
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김희철,남창규 世明대학교 한의학연구소 2002 韓醫學硏究所 論文集 Vol.4 No.-
This study was undertaken to define the effect of Diospyros Kaki L. Radix on the phenylephrine-induced arterial contraction and the mechanism of Diospyros Kaki L. Radix-induced relaxation. In order to investigate the effect of Diospyros kaki L. Radix on contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of Diospyros kaki L. Radix induced relaxation, Diospyros kaki L. Radix extract infused into contracted arterial strips induced by phenylephrine after treatment of indomethacin, N_(t) nitro-_L-arginine, or tetraethylammonium chloride, and Ca^++ infused into contracted arterial strips by phentlephrineafter treatment of Diospyros kaki L. Radix in a CA^++ free solution. Diospyros kaki L. Radix relax arterial strip with or without endothelium contracted by phenylephrine, but in the strips without endothelium, Diospyros kaki L. Radix-induced relaxation was significantly inhibited. The endothelium-dspendent relaxtion induced by Diospyros kaki L. Radix was decreased by the pretreatment of N_(t) nitro-_L-arginine, but it was not observed in the strips pretreated with indomethacin or tetraethylammonium chloride. When Ca^++ was applicated the strips which were contracted by phenylephrine in a Ca^++ free solution, arterial contraction was increased. But pretreatment of Diospyros kaki L. Radix inhibited contractile response to Ca^++. We suggest that Diospyros kaki L. Radix may directly suppress influx of extra-cellular Ca^++ and indirectly suppress influx of extra-cellular Ca^++ though the formation of nitric oxide in the vascular endothelial cells.
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김희철 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.1
Schizophrenic patients frequently exhibit specific cognitive deficits, particulary in the areas of attention, executive function, and memory. These impairment may represent a central feature of the disease process and not simply a consequence of non-specific deficits in motivation or psychotic symptomatology. Neuropathological and neuroimaging studies in schizophrenic patients provide evidence for abnormalities in the prefrontal and temporal cortical system. Cognitive impairment in schizophrenia may greatly impede social and occupational functioning. Furthermore, conventional neuroleptics cause additional loss of cognitive function. Cognitive function may be subtly impaired at early phase of the disease and may be abruptly declined after the onset of psychotic symptoms. Thereafter, the cognitive impairment tends to remain fairly stable. It is thus important to minimize cognitive decline in first episode patients. Good cognitive function is important for enabling social rehabilitation and maximizing quality of life. The primary target for treatment of schizophrenia in future should be to ameliorate cognitive deficits as well as psychotic symptoms. Atypical antipsychotics, such as clozapine or risperidone, is promising agent concurring with this object.
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김희철,박재우,김계홍 제주대학교 방사능이용연구소 2003 연구보고 Vol.17 No.-
When the water with a high radon concentration is taken, a portion of radon goes into the lung and it clings to a radon decayed daughter nuclides Po-218, Bi-214, Po-214 of radon, thus it may cause lung cancer. The spring-water is used for drinking water in most region of Jeju Island. There may be an internal exposure when habitants of the province took the spring-water. The safety of the spring-water used for drinking water is examined through the measurement of radiation quantity of Rn-222 in the spring-water. In this study, HPGe detector was used. As gamma-ray peak of the 351.9keV that is released from the daughter nuclide Pb-214 produced by decay of Rn-222 in spring-water was measured. Then the Rn-222 activity in a spring-water was determined. Through the investigation of the radioactive content in the ground water performed by National Institute of Environmental Research on a national scale in 2002, Rn-222 activity in the some area of Jeju Island can be known. But it is not much different from this measurement. There has not been yet a limited value about radon in Korea when the limited value about radon is 4000pCi/L (~148㏃/L) in U.S. EPA.
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