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徐光潤 中央醫學社 1975 中央醫學 Vol.28 No.3
The author observed two cases of convulsions with sernicomatose conditions during lithium carbonate treatment. In the first case, a man, aged 32, developed typical grand mal like seizure after 8 days of the treatment with 1200mg of lithium and 300mg of chlorpromazine daily. In the second case, a man, aged 34, developed same manifestations as observed in the first case except the occurrence of seizure attack after 17 days of the treatment. The convulsive attacks and semicomatose conditions were disappeared after immediate withdrawal of lithium. The development of convulsions of both cases seemed not to be related with the overdosage of lithium.
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Imipramine과 Amitriptyline에 依한 急性 腦症侯 및 幻視에 關한 症例
徐光潤,姜致永 최신의학사 1967 最新醫學 Vol.10 No.10
Recently, acute brain syndrome and visual hallucinations during imipramine and imipramine-like drugs administration have been reported and discussed by many. However, the relationship between acute brain syndrome and visual halluchinations by imipramine and imipramine-like drugs has not been determined. Some reported visual hallucinations only, some acute brain syndrome and others visual hallucinations with acute brain syndrome. We observed 2 cases of visual hallucinations with acute brain syndrome and I case of visual hallucinations without mental confusion. In the 1st case, a man, aged 58, developed typical delirium with visual hallucinations after 16 days of treatment, culminating in 250mg of imipramine daily. In the 2nd case, a man, aged 28, developed delirious syndrome with visual hallucinations after 33 days of treatment, culminating in 125mg of amitriptyline daily as well as E.S.T. In both cases above mentioned, we administrated antiparkinsonian agent together. In the 3rd case, a woman, aged 58, developed-vivid visual hallucinations without any disturbance of consciousness after 14 days of treatment, culminating in 150mg of amitriptyline daily. In these 3 cases, the formal structure of visual hallucinations had various forms from simple ones such as blue sparkles and yellow stars etc. to complex ones with thing-quality such as crawling snake and mother etc. The acute brain syndrome and visual hallucinations of these 3 cases were disappeared after gradually decreasing the daily dosage of imipramine and amitriptyline. The development of the acute brain syndrome and visual hallucinations had no correlation with the changes of the clinical pictures of underlying depression in all 3 cases.
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서광윤 고려대학교 의과대학 1979 고려대 의대 잡지 Vol.16 No.2
Six cases of the Capgras syndrome, a rare psychopathological manifestation, were encountered past 5 year period at the neuropsychiatric department of the Korea University Hospital. All of these cases mere studied clinically and analytically. The results were as follows ; 1. Four of all patients were female and two were male. 2. The ages of all patients were in the twenties. 3. For all patients, the main misidentified objects in their delusional system were the father or the mother, or both and the secondary objects were the siblings and other relatives. 4. All patients mere psychotic, and the nosological setting in which the syndrome developed was manic-depressive psychosis in four cases and schizophrenia in two cases. 5. None of the patients had any clinical symptoms and signs suggesting organic brain disorders. 6. Three of all patients developed the syndrome years after the onset of basic illness and the syndrome developed simultaneously with the basic illness in another three cases. 7. The outcome of the syndrome in these subjects seemed to be dependent upon the therapeutic success with the psychosis of with the syndrome was only an aspect. 8. The illusion of Fregoli associated with the Capgras syndrome was seen in one case. 9. The psychodynamic factors as the main role in the syndrome-formation of the subjects seemed to be ambivalent conflicts and unresolved Oedipal complex to the principal misidentified person.
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徐光潤 우석대학교 의과대학 1968 우석의대잡지 Vol.5 No.1
The focus of this study was to investigate the characteristic aspects of the chief complaints of depression in Korea. Their chief complaints expressed in multidimensional ways from psychical ones to various somatic symptoms were assessed in the contents and extents. The 268 cases of depression of this study were comprised from 209 cases of neurotic depression, 7 cases of manic-depressive psychosis, 40 cases of involutional depression and 12 cases of psychotic depression. Their complaints were classified into 107 items and these items again were grouped into 4 major categories according to the method of Grinker et al. The results obtained from this phenomenological study were summarized as follows: 1) Females were 1.7 times higher than males in the hospital incidence of depression. 2) In the distribution of ages, the highest frequency were observed in the period of 30-34 and 50-54 years of age in male and 25-29 and 40-44 years of age in female. 3) The complaints in the category of somatic behavioral manifestations occupied the highest incidence and variety comparing with the other ones of 3 major categories and complaints of gastrointestinal manifestations occupied the highest incidence of all. 4) From the analyses of the incidence of complaints, it is supposed that the excellent predictors for clinical diagnosis of depression are poor appetite (62.7%), difficulty in getting sleep (53.7%), physical weakness and fatigue (51.9%), dull headache (48.9%), palpitation (47.4%), indigestion with epigastric discomfort (44.8%), chest tightness (43.7%), constipation (39.2%), lack of drives (37.3%), dizziness (36.2%), multiple dreams (35.4%), wakefulness during night (34.3%), impaired concentration and memory (32.1%), anxiousness (31.0%), oral dryness and thirst (30.2%), suicidal thought (28.7%), sadness and blue (28.0%), early morning awakening (25.4%), and retarded thought process (24.3%). In addition, easy distractibility (22.0%), restlessness (22.0%), irritability (21.3%), pessimism (19.4%), and decreased sexual feelings and interests (19.4%) are also supposed to be relatively good predictors. 5) The many anxiety manifestations among the excellent and good predictors betray that the material selected for this study was largely composed from anxious depressions.
KISS
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