도장작업시 유해인자들의 노출수준과 작업환경관리실태

이세기,문덕환,이채관,황용식,선병관,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives: For the purpose of preparing the fundamental data and assessing the status of exposure level of chemical substances in painting process. Methods and Materials: The author determined the concentration of organic solvents, lead(Pb), Chromium(Cr), and Toluene-2, 4-diisocyanate(TDI) in air of painting process to 90 industries classified by 15 types of manufacturing industry during a period from Jan. 1st 2001 to Dec. 31st 2001. Results: The results were as follows: 1. The geometric mean level of each chemical substance was 0.1706 ppm for exposure index in organic solvents, 0.0019㎎/㎥ for Pb, 0.0024 ㎎/㎥ for Cr, and 0.0004ppm for TDI, respectively. 2. The exposure level of each chemical substances by type of painting was the highest in dipping and brush painting for organic solvent, in spray-painting for TDI, and in spray gun-painting for Pb and Cr, respectively. 3. The exposure level of each chemical substances by type of local ventilation equipment was higher in enclosed and booth type for organic solvents. Cr, and TDI, and in exterior type for Pb, respectively than those of other types. 4. The exposure level of each chemical substances by type of hazardous material arresting media was higher in using water for organic substances, in using bag filter for Pb, TDI, respectively than those of other types. Conclusion: According to above results, this study suggests that the exposure level by type of industry exceeded the exposure level in wooden furniture and metal furniture manufacturing industry for organic solvents and Pb, respectively.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

화학적 요부 교감신경절 차단에서 한 분절 차단과 두 분절 차단의 비교

김종일,이규종,이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

Chemical Lumbar Sympathetic Block: Comparison of One- Versus Two-needle Techniques Chul-Jun Mun, M.D., Kyu-Jong Lee, M.D., Sang-Gon Lee, M.D., Jong-Il Kim, M.D.^* Jong-Suk Ban, M.D., and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea ^*Kim Jong Il Pain Clinic, Daegu, Korea Background: It was frequently noticed in the course of performing a two-needle sympathectomy, that satisfactory spread of contrast solution could be produced by injection through only one of the needles. This led to a closer examination of the merits of single-needle technique. Methods: Forty patients were randomized into two groups. Patients in the single-needle group (n = 20) were injected at the second or third lumbar sympathetic ganglia, while patients in the two-needle group (n = 20) were injected at the second and thired lumbar sympathetic ganglia. Lumbar sympathetic blocks were performed using 3 ml of alcohol and the spread of injectate was verified with C-arm fluoroscopy. The indicators of a successful sympathetic block are increasing skin temperature, decreasing pain, and anhidrosis in the distal extremity. Results: The duration of anhidrosis was 12.2 ?? 2.6 months (mean ?? SD) in the single-needle group versus 13.6 ?? 3.6 months (mean << SD) in the two-needle group. Conclusions: As these results were not significantly different from those obtained in patients having considered to be effective for a neurolytic ;i,bar sympathectomy. (korean J Anesthesiol 2001; 41: 439~443)

위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

蒸氣터빈에서 패킹 씰이 터빈 性能에 미치는 영향에 대한 比較 硏究

이병수,김경철 大田産業大學校 1999 한밭대학교 논문집 Vol.16 No.1

This study is the effect on turbine performance due to steam leakage rate passed to N2 packing seal in steam turbine. After the A type seal(constant pressure type seal) or the B type seal(variant pressure type) were installed in the position of N2 packing seal, the test was performed 3 times by changing the temperature of main steam and reheat steam(510℃ ~538℃) under the steady-state operation. It is confirmed that the B type seal is more effective than the A type seal. The results of the study can be summarized as follows ; 1. In the case of A type seal and the B type seal, the steam leakage rate is respectively 8.2% and 2.7%. 2. In the B type seal, the internal efficiency of the intermediate pressure turbine is 89.49% and is improved as much as 1.35% compared with the A type seal. Accordingly, it can be confirmed that as the steam leakage rate is increased by 1%, the internal efficiency is decreased by 0.25%. 3. Also, it can be examined that as the B type seal is used, the heat rate and the efficiency are respectively improved by 11.39 kcal/kWh and 0.27 %.

한국지역개발의 지역지표를 통한 실증적 분석연구

이병철 울산대학교 1989 연구논문집 Vol.20 No.2

본 연구는 지역의 개면분석을 통해 지역을 이해하는데 필요한 지표의 의미를 부각시키고 필요한 지표군을 정밀분석하여 한국의 지역개발의 특성과 도시성장의 원인을 추론해 낼 수 있는 지표를 발견, 제시하고 이를 통해 시계열적으로 매년 지속적으로 측정하 수 있는 지표체계를 구축시킴과 동시에 실증적으로 한국의 지역개발상황에 적용하여 지역개발정책에 필요한 관리지침고 정책적 대안책을 제시하는데 연구의 목적이 있다. 이를 위해 11개의 도시를 선정하고 다음과 같은 지역지표체계를 설정하여 실증적 검증을 하였다. 1.지역지리학적 지표와 지역인구학적 지표 2.지역경제학적 지표 3.지역복지및 서어비스지표 4.지역위락 및 문화지표 한국 지역 개발의 지역지표를 통한 실증적 분석에서 발견된 사실들은 다음과 같다. 첫째, 도시의 기능적 특성에 따른 지역개발의 차이가 나타났다. 둘째, 한국의 도시발전은 인구증가와 밀접한 관계를 지니며 인구증가는 자연적 증가요인보다 인뒤 적인 인구이동요인에 의해 크게 좌우된다. 따라서 인구 밀집지역이 도시발전을 촉진시키고 그렇지 못한 지역은 쇠퇴한다. 셋째, 인구억제 및 분산정책, 산업화 정책추진, 교통수단의 변모, 소득수준이 향상, 도시정책에 대한 대국민홍보, 국민의식 변화, 보건복지, 교육정책의 영향들이 도시의 성장에 크게 영향 을 끼친다. 네째, 중부권 개발정책등과 같은 정책적 배려나 행정수도로의 전환과 같은 도시기능의 변화가 지 역발전에 커다란 영향요소로 대두되고 있다. 다섯째, 도시의 재정과 도시성장과는 깊은 상관성을 지닌다. 여섯째, 의료 및 사회복지시설은 도시의 기능적 진화에 따라 증가되고 있으며 대도시 권역을 중심 으로 밀집되어 있다. 일곱째, 위락 및 문화공간이 절대적으로 부족하며 기형적 도시개발에 의해 오히려 감소되는 경향 도 있다. 이러한 분석 결과에 따라 제기되는 잇슈를 해소키 위한 정책적 대안은 다음과 같다. 첫째, 지역개발자원에 대한 분배의 공정성과 형평성의 유지 그리고 지역적 편견에 따른 정책적 배 려들을 배제시키고 국토의 균형화된 발전을 위한 엄밀한 의미에서의 지역적 특성에 맞는 그 러면서도 정책간의 상관성ㅇ르 고려한 균형된 시각의 개발전략을 구상해야한다. 둘째, 양적이고 가시적인 홍보및 선전위주의 지역개발은 배제되어야 하며 현싯점에서 비생산적이 고 비가시적이라 하더라도 미래지향적이고 전향적인 입장에서 긍정적 평가를 받을 수 있는 분야는 개발될 수 있는 질적을 고양된 지역개발정책이 강구되어져야한다. The purpose of this paper is to analyze the characteristics of the application of indicators to regional development in korea through a survey of the literature, leading to identification of indicator, and to empirical analysis of korean regional development raw data. This effort to identify and ideographic theory of korean regional and urban studies especially, in the view of the policy sciences, through the analysis of korean regional development trends, by utilizing regional indicators, estends its focus to forecasting the future korean regional development. For this study, eleven cities are selected and the following indicators are considered 1.Regional geographic indicators and regional demographic indicators. 2.Regional economic indicators 3.Regional welfare and service indicators 4.Regional leisure and culture indicators The results of this analysis indicate as follows: 1.Urban and regional functional characteristics influence to regional development differences 2.Korean urbanization correlates with population growth 3.Urbanization has influence as: Zero population growth movement, population relocation policy, economic development policy, industrialization, transportation device change, income growth, public relation, citizenship change, medicare, welfare and educational policy, etc. 4. Regional development have influenced by policy bargaining, and urban structure and function change 5.Urban finances correlate with urban growth 6.with urban functional evolvement, medicare and social security facilities are increased, and then these facilities are located densely in the metropolitan area 7.Leisure and cultural space run short because of malfuncional urban development policy. Finally, some recommendations are drawn 1.Central and local government authoritied concern about equality and fairness of regional development. It is considered the fact that the correlationship among many regional policies are important. 2.Central and local government authoritied descard propaganda and visible performance oriented regional policy. They should pursuit the future oriented regional policy even though it is unvisible and unproductive performance.

세계행정학의 미래전망에 관한 계량적 연구:델파이 기법을 중심으로한 회귀,요인분석

이병철 울산대학교 1989 연구논문집 Vol.20 No.1

본 연구는 한국행정의 나아갈 미래상을 조망해 보고 점망해 보기위해 델파이기법을 통한 계량적 접근으로 세계행정학의 추세를 미래예측적 시각에서 관망해보려고 하며 여기에서 도출된 세계행정학의 흐름이 향후 한국행정학도 조우하게될 사항으로 이해하여 한국행정의 미래상을 정립하는데 있어 본보기가 될 수 있는 준거틀을 구성해보려고 한다. 나아가서는 이러한 미래전망의 준거틀에 정확성과 객관성을 확보하기위해 세계행정학의 흐름을 계량적으로 접근하여 실증적 지표발굴을 통해 개념화 시키고 그 이론적 맥락을 행정학의 범세계적 변화추세 속에서 예측정리하려고 시도하였다. 이러한 노력은 한국행정학의 재조명하고 앞으로의 발전 방향을 모색하는데 있어 보다 보편타당성이 있는 이론적 모델을 제시해 줄 것이다. 이러한 연구목적에 따라 연구를 시도한 결과 다음과 같은 연구 결과를 도출하였다. 첫째, 금후 행정학에 밀접한 영향을 줄 수 있는 세계환경으로 컴퓨터에 기인한 기술혁신, 국제테러리즘, 인구문제, 핵파괴, 비공공조지과 민간기업활용증대, 식량문제, 보호주의정책, 군부 개입등이다. 이러한 세계환경의 영향을 금후 행정학과 관련지어 살펴보면 컴퓨터나 기술혁신은 실증적이고 계량적인 분야의 발전을 상징할 수 있고 국제테러리즘, 비공공조직과 민간기업의 활용증대, 보호주의 정책, 군부의 개입 등은 정치적 맥락의 가치규범적 분야의 발전을 예기할 수 있고 실업, 식량문제, 연구문제들을 사회보장이나 복지행정분야의 비중강화를 의미한다 하겠다. 둘째, 금후 행정학과목으로써 계속 발전하고 새롭게 발생할 분야로는 조직이론, 정보과학, 컴퓨터학, 정책과학, 형평론, 공공윤리 등이다. 세번째로, 계속적용, 원용, 창출될행정학 연구접근방법으로 체계접근, 구조기능적 접근, 컴퓨터 시물레이션, 사례접근법, 비용편익, 서어베이 연구, 윤리적 접근 등이 선호되고 그에 못지않게 실증적, 계량적 및 가치, 규범적 접근이 같이 혼용되어 사용되며 실증적, 계량적 접근이 괄목하게 사용 될 것임을 예측하고 있다. 이것은 세계환경이나 금후 발전할 행정학 이론분야에서 기술혁신이나 정보과학, 컴퓨터학 등의 발전이 이를 뒷받침해 준다. 네째, 비교분석이 이루어질 행정학의 주요대상영역으론 예산분야, 문화적 가치분야, 공행정 대 민간행정, 인사분야, 공기업, 관료제의 병리, 조직발전, 공공정책집행, 행정개혁, 행정과 환경 등을 들 수 있다. 이는 앞으로 보편적 일반이론을 추구키위해 각 나라의 예산체계나 예산구조, 그 내용 그리고 문하적 요인에 의한 이론의 차이등을 폭넓게 연구하게 되고 객관적 이론 도출을 위한 연구분야는 상기분야들이 각광을 받게 될 것이라는 점을 알 수 있는 것이다. 마지막으로 토착화의 개념과 보편적 세계행정학의 정립을 위해선 토착화는 개념이나 이론등이 새로운 아이디어나 체계와 절차에 의해 수정되고 문화적 패턴이나 전통적 형태등의 변화가 수반되는 상호적응의 과정이며 수정된 이론과 방법들이 새로운 문화속으로 침잠해 들어가 기존의 문화권에서의 의미를 상실 또는 변질시키는 것을 의미한다 하겠다. 보편적 세계행정학의 정립이란 비록 문화나 여건이 다르다해도 행정학이론이 현상을 설명하기위해 사용되어진다면 그것은 일반이론이 되는 것이란 입장을 취하고 있는 것이다. This study attempts to identify an ideographic theory of korean public administration through the analysis of indigenization trends, by utilizing delphi exercise, extends its focus to forecasting the future development of theory and methods in korean public administration in a world context. The more inward looking pattern of korean public administration study will be influenced in the future by the world environment of technological innovation, protectionism, terrorism, population, nuclear weapons, and military involvement in politics. The results of a delphi analysis, collecting the responses of professional analysts and professors related to public administration and government officials in the pacific regions indicate that the influential factors expected to affect public administration in the future are: 1) the changing pattern of ideological and belife systems(25.6%) 2) international conflict and terrorism(23.2%), 3) computer and technological innovation(19.2%), and 4) population, unemployment, food shortage, military involvement in politics etc.(16.8%). The study also predicts that the most likely theoretical contents in the future are: 1) organization theory(26.9%), 2) information science and computer science(23.3%), 3) equity and ctizens' participation(21.7%). Therefore it is imperative that quantitative methods be used to develop computer and technological innovation in the business of government, and normative analysis will be helpul to pursue such factors as international terrorism and the rising role of private organizations and business in government. This studyreveals that welfare administration is likely to strengthen its theoretical implications to explore unemployment problems, food shortages and the population explosion. According to delphi analysis, organization theory, information science, computer science, policy science and public ethics will be further developed, while both empirical and normative approaches are likely to be developed at the same time. The public administration experts also forecast that the most likely methods are: 1) quantitative computer simulation(29.8%), 2) systems analysis(26.4%), 3) structural approach(16.5%), and 4) normative analytical methods(11.6%). The study also demonstrates that comparative administration will continuously expand in the following areas: 1) the traditional theory of organization (31.7%) 2) policy science(19.5%), 3) environment, energy, urban and regional affairs(12.2%), 4) personnel, budgeting and public corporation(13%), and public ethics(13%). Specifically speaking, systems analysis, structural-functional approach, computer simulation, case study, cost-benefit analysis and surveys methods are the most promising methods to be utilized. The areas to be developed in comparative administration include budget management, administrative culture, personnel administration, bureaucracy, organizational development, policy analysis, and private and public management interaction. The indigenization of public administration study in a certain country may be defined as an interaction process through which a particular theory is adapted and revised to fit with existing theory and individual administrative culture.

대사증후군 환자에서 고감도 C-반응 단백의 성별차이

이상호,정미홍,이순례,유병철,이용환 고신대학교의과대학 2006 고신대학교 의과대학 학술지 Vol.21 No.2

Background: High-sensitivity C-reactive protein (hsCRP), the classic acute-phase reactant, is an extremely sensitive systemic marker of inflammation. A variety of factors seems to influence hsCRP levels. The aim of this study was to elucidate the gender differences in the association between hsCRP and features of the metabolic syndrome (MS) among Korean. Methods: The study population included 1,283 men and 3,265 women aged 40 years and over who were enrolled in Korean Health Examinee Cohort. They were examined in 10 General hospitals from November 2004 to September 2005. The height, weight, waist circumference, and systolic and diastolic blood pressure of the subjects were examined and on concentrations of fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, and hsCRP in peripheral venous blood were measured. Results: In both sexes, there were significant positive correlations between age, smoking, body mass index, waist circumference, systolic and diastolic blood pressure, triglyceride, and fasting glucose and hsCRP, whereas significant negative correlations were present between drinking, and HDL cholesterol and hsCRP. Mean concentrations of hsCRP in men with 0, 1, 2, 3, and ≥4 components of MS were 0.13, 0.16, 0.18, 0.20, and 0.22 mg/L, respectively. The respective mean concentrations of hsCRP for women were 0.08, 0.09, 0.12, 0.14 and 0.14 mg/L. Results of stratified analyses by the number of components of the metabolic syndrome of 0, 1, 2, 3, and ≥4 revealed that an increase in hsCRP concentrations was greater in men than women with an increased number of components of the MS. Conclusion: There was a difference in concentrations of hsCRP between men and women, and especially an increase in hsCRP concentrations associated with risk factor-clusteringof MS was more prnounced in men.