부산지역 일부 제조업 산업장의 작업공정별 분진농도

문덕환,김국규,황용식,강동묵,박명희,손병철,김정원,이채언 인제대학교 2001 仁濟醫學 Vol.22 No.1

Objectives: For the purpose of preparing the fundamental data to improve the working environment and prevent the occupational disease due to dust in the manufacturing industry. Materials and Methods: The authors measured the levels of dust in 123 factories in Pusan area according to the types of industry and the working process from Jan. 1st 1998 to Dec. 31st 1998. Results: 2.05±1.20mg/m3 was the mean concentration of the 1st class dust in manufacture of fabricated metal products, which exceeded the threshold limit value, 2.00 mg/m3 . 3.55±3.23 mg/m3 was dust in manufacture of the highest mean concentration of the 2nd class other transport equipment, 3.04±1.83 mg/m3 was that of the 3rd class dust in manufacture of furniture (manufacturing not especially classified). And these values were within their own threshold limit values. Conclusions: The mean concentrations of 1st class dust according to the working process were 4.81 mg/m3 for crushing, 2.64 mg/m3 for foaming, 2.57±1.16 mg/m3 for grinding, 2.57 mg/m3 for melting. 4.16 mg/m3 for sand removing in basic metal product manufacturing industry, and 2.05 mg/m3 for drilling in manufacture of fabricated metal products. The mean concentrations of the 2nd class dust according to the working process were 10.11mg/m3 for shooting, 6.26 mg/m3 for drilling, and 8.10 mg/m3 for filling in manufacture of other transport equipment, and all of them exceeded threshold limit value.

부산지역 지하철역의 중금속 오염도에 관한 연구

문덕환,이명직 인제대학교 1999 仁濟醫學 Vol.20 No.1

부산지역 일부 지하칠역 내ㆍ외를 대상으로 중금속 오염정도를 조사하여 파악함으로써 지하철을 이용하는 일반시민과 현장에서 근무하는 근무자의 생활환경권 및 중금속 오염의 저감대책수립에 대한 기초자료를 제공할 뿐만 아니라 시민 건강관리에 일조가 되고자 1995년 10월7일부터 1996년 3월까지 부산지역 10개 지하철역을 대상으로 하여 5개 중금속(Pb, Cr, Cd, V, Ni)에 대하여 원자흡광분광광도계를 이용하여 정량하였다. For the puepose of preparing the fundamental date on heavy metal concentration in air of subway station, and contributin the health improvement of people who using and working in subway, the author determined atmospherip heavy metal concentration in and outside of 10 subway station in pusan area by of of flameless atomic absorption spectrophotometer from Oct. 1995 to Mar. 1996. The results were as follows ; 1.The inside and outside average concentration of subway stations ; Lead: 0.7365㎍/㎥, 0.4417㎍/㎥ Chromium : 1.9177㎍/㎥, 0.5991㎍/㎥ Cadmium: 0.0177㎍/㎥, 0.0085㎍/㎥ Vanadium : 0.0971㎍/㎥, 0.0466㎍/㎥ Nickel: 1.5067㎍/㎥, 0.4685㎍/㎥ 2.As a result of statistical analysis, the inside average concentration of heavy metals except cadmium were higher than the outside (P<0.05). 3.In the inside average concentration of heavy metal following time, lead was high in A.M.(P<0.05). The others were high on night, but only vanadium showed significance (P<0.05).

중금속 취급 사업장의 업종별 공정별 중금속 농도에 관한 연구

문덕환,박명희 인제대학교 1999 仁濟醫學 Vol.20 No.1

부산지역 제조업 산업장 가운데 중금속을 취급하는 151개 사업장을 대상으로 업종별, 공정별 공기 중 유해 중금속의 종류와 그 정도를 파악함으로써 산업장 내의 체계적인 작업 환경 관리 계획 및 수행에 도움이 되게 할 뿐 아니라 각 업종과 공정에서 발생하는 중금속의 적절한 보건관리 대책 마련에 기초 자료를 제공하고자 본 연구를 시행하였다. 본 연구의 결과로 대부분의 업종들은 허용 기준치를 초과하지 않았으나 금속 주조업의 용해공정, 기타 조립금속 제품 제조 및 금속 처리업의 용해공정, 조명장치 제조업의 베이싱 공정은 허응 기준치에 근접하거나 초과하였다. 이에 이들 공정은 근로자들의 건강 관리를 위해 보다 적극적인 작업 환경 관리가 필요하다고 사료된다. In order to improve the working environment for health promotion and prepare the fundamental data on heavy metal concentration in the air of manufacturing industry, the author determined heavy metal (Pb, Cr, Mn, Ni, Zn) concentration of 151 manufacturing industries in Pusan area by type of industry and working process with flameless atomic absorption spectrophotometry (Perkin-Elmer 4100ZL) from January 1997 to June 1997. The results were as follows : 1. Geometric mean concentration in ambient air for each heavy metal (Range) 1) Pb : 0.0100mg/m3(0.0013 ∼0.0945mg/m3) 2) Cr : 0.0028mg/m3(0.0005 ∼0.0258mg/m3) 3) Mn : 0.0103mg/m3(0.0002∼1.9830mg/m3) 4) Ni : 0.0050mg/m3(0.0006∼0.0413mg/m3) 5) Zn : 0.8473mg/m3(0.1471 ∼4.8658mg/m3) 2. Geometric mean of Pb in melting process of the casting of metals manufacturing industry among total subjects industry was 0.0945mg/m3, it was exceeded the thleshold limit value. 3. Geometric mean of Zn in melting process of the casting of metals manufacturing industry among total subjects industry was 4,8658mg/m3, it was closed to the thleshold limit value.

가스 크로마토그래피를 이용한 발암성 혼합 유기용제의 동시정량분석법 개발

문덕환,김종근,황용식,이용희,김정호,박명희,이종태,이채언 인제대학교 1998 仁濟醫學 Vol.19 No.2

산업장에서 사용되는 많은 유기용제 중 발암성 문제가 대두됨에 따라 발암성 유기용제들에 대한 폭로량 평가는 근로자들의 건강 관리와 작업환경 관리의 진보에 있어서 기본적이고 필수적인 과정이지만 이를 정성 및 정량적으로 정확히 분석하여 폭로 평가를 한다는 것은 어려운 점이 상당히 많다. 이에 본 연구자는 가스크로마토그래피를 이용하여 산업장 공기중 발암성으로 확인 및 추정된 혼합 유기용제 농도에 대한 동시정량방법을 개발하기 위하여 컬럼. 주입구 및 검출기의 온도를 변화시켜 14종의 발암성 혼합 유기용제의 최적 분리 조건을 제시하고, 이들 자료를 바탕으로 산업 장에서 직업성 폭로에 의한 직업병 예방과 발암성 혼합 유기용제 정량법의 기초 자료를 제공하고자 한다. In order to prepare the fundamental data for determination method on carcinogenic substance of organic solvents and prevent to occupational disease of workers by assessing the occupational exposure in industry, the author developed a simultaneous determination method on 14 carcinogenic organic solvent by gas chromatography with changing the temperature of column, injector and detector. The results were as follows ; 1.The optimum condition of this method were 35-150℃ for colum temperature. 250℃ for injector and detector temperature with capillary OV -1 column at 0.2 kg/㎠ of inlet pressure. 2.The recovery rates of 8 carcinogenic organic solvent including 1,1.2-Trichloroethane were 90% and over.

도시와 농촌 비둘기 및 인체혈액중의 Vanadium 농도 산정에 관한 연구

문덕환,김준연,김정균 인제대학교 1985 仁濟論叢 Vol.1 No.1

This experiment determined the vanadium concentration in pigeon liver and lung tissues from rural and urban areas and .in bloods of workers (male 20, female 6) by carbon furnace Atomic Absorption spectrometry. The purpose of this experiment was in investigating the status of vanadium pollution in atmosphere. The summarized results were as follows : 1.The mean concentration of vanadium in pigeon liver and lung tissues from rural areas was 36.9±2.04ppb and 58.9±2.94ppb, respectively. 2.The mean concentration of vanadium in pigeon liver and lung tissues from urban areas was 64.0±2.62ppb and 91.7±4.26ppb, respectively. 3.The mean concentration of vanadium in pigeon liver and lung tissues from urban areas was more higher than that of rural (P〈0.05). 4.The mean concentration of vanadium in blood of workers(male 20, female 6) was 23.7±3.48ppb.

대동맥궁 대동맥류에서 Hybrid 수술적 치료

문덕환,김희중,정철현 대한흉부외과학회 2009 Journal of Chest Surgery Vol.42 No.4

Aortic arch aneurysm generally requires an urgent treatment due to the risk of catastrophic aortic rupture. However, conventional surgery for aortic arch repair still carries significant risks of postoperative morbidity and mortality, especially in patients with old age. In an effort to correct the aortic pathology while minimizing the risks of complications, we performed a hybrid technique which comprises the off pump arch vessels debranching and endocascular aortic stent grafting in an 86-old male patient with an aortic arch aneurysm. 대동맥궁 대동맥류는 파열의 위험성으로 인해 적극적이며 응급에 준하는 치료가 필요하다. 그러나, 전통적인 방법의 대동맥궁 치환술은 나이가 많거나, 여러 질환이 동반된 경우 수술 후 생길 수 있는 위험 및 합병증이 높아 수술을 쉽게 시행하기 어렵다. 저자들은 대동맥궁 대동맥류를 가진 86세 남자 환자에게 일반적인 수술이 아닌 Hybrid 수술(심폐기를 사용하지 않은, 혈관 내 스텐트 그라프트 삽입술 및 탈분지 혈관 연결)을 시행하여 성공하였기에 문헌고찰과 함께 보고하는 바이다.

부산지역 일부 공무원 및 교직원의 고혈압에 관한 조사 연구

문덕환,최재일 인제대학교 1998 仁濟醫學 Vol.19 No.2

부산 지역의 공무원 및 교직원 3,507명 중 남성 1,553명(평균연령, 39.3±9.7세), 여성 1,974명(평균연령: 30.3±8.3세)을 조사 대상으로 집단 검진을 실시하여 고혈압 유병율 산정 등 고혈압의 실태를 파악함으로써 이들의 건강 증진에 기여함은 물론 고혈압 관리에 일조가 되게 할 뿐만 아니라 추후 이들 분야의 기초 자료를 제공하고자 1996년 4월 1일부터 동년 10월 30일까지 6개월에 걸쳐 본 조사 연구를 시행하였다. This study was conducted for the purpose of obtaining the fundamental data on hypertension and contributing to health improvement of public official and school personnel, the author carried out the survey for the prevalence rate of hypertension and several factors related with the occurence of hypertension on 3,507 numbers(Male:1,553, Female: 1,974, Average Age:Male:39.3±9.7 years old, Female:30.3±8.3 years old) of public officials and school personnels in Pusan area for 6months from April, 1996. The obtained results were as follows ; 1.The prevalence rate of hypertension among total subjects was 3.9%, and it was gradually increased with aging (P<0.05). 2.The rate of obesity (120% and over of standard body weight) in hypertensive group was higher than normotensive group (P<0.05). 3.The mean concentration of total cholesterol level in hypertensive group was 246.1 46.9mg/dl, and it was increased as blood pressure increased(P<0.05). 4.The abnormal rate in funduscopic findings of hypertensive group was 36.2%, and it was gradually increased as blood pressure increased (P<0.05). 5.The abnormal rate in electrocardiographic findings of hypertensive group was 38.7%.

AESOP을 이용한 좌측 최소개흉술하 동맥하형 심실중격 결손증 교정술 −1예 보고−

문덕환,이재원,조현진,제형곤,정성호,주석중,정철현,송현 대한흉부외과학회 2008 Journal of Chest Surgery Vol.41 No.5

Minimally invasive cardiac surgery using AESOP (Automated Endoscope System for Optimal Positioning) offers certain advantages such as better a cosmetic outcome, a shortened post operative recovery time and a shorten hospital stay, and these advantages are not achieved by conventional cardiac surgery. We report here on our first robot-assisted (AESOP) left minithoracotomy surgery in a 26 year-old female with a subarteral ventricular septal defect, and this might have been treated by median sternotomy before the development of AESOP.

가스 크로마토그래피를 이용한 복합유기용제으 분리조건에 관한 연구

문덕환,이채언,김종갑,유영진,한용수,조규일,박헌인 인제대학교 1994 仁濟醫學 Vol.15 No.4

본 연구는 신발제조업, 페인트 제조업에서 주로 사용하는 23종(벤젠, 톨루엔 등)의 복합 유기용제를 대상으로 Gas Chromatography를 이용한 분리조건을 검정함으로써 산업 장에서의 작업환경을 보다 정확히 파악하게 할 뿐만 아니라 이를 취급하는 근로자들의 직업병 예방 뿐만 아니라 이들 분야의 기초자료를 얻고자 연구를 하였다. 가스 크로마토그래피를 이용하여 불꽃이온검출기(FID)로 검출온도 및 주입구의 온도를 변화시키면서 Capillary OV-1 컬럼을 이용한 가장 좋은 분리를 나타낸 조건은 컬럼온도가 35℃-150℃(6min Hold, 5℃/min) 조건으로 점진적인 변화를 시키면서 검출기 및 주입구의 온도가 250℃인 경우였으며, 압력은 0.41kg/cm2이었다. In order to described for the separate and the determination of concentration of 23 organic solvents (benzene, toluene, MEK, et al.) which is used extensively as solvents in the chemical industry, using gas chromatography(FID) with capillary column OV-1. The best analysis conditions were as follows : Gas Chromatography(GC) setting were the detector and the injector temperature 250℃. The temperature of column oven was initially 35℃, hold 6 min and then increased to 150℃ at 5℃/min. Inlet pressure of the carrier gas was 0.41kg/cm2.

도시지역 건강한 성인 여성의 뇨증 중금속 농도에 관한 연구

문덕환,송인혁 인제대학교 1999 仁濟醫學 Vol.20 No.1

1994년 1월 27일부터 1994년 2월 6일 까지 서울, 부산, 천안, 함암의 4개 도시에 거주하는 20세 이상의 비흡연 건강한 성인 여성 143명을 대상으로 인체에 유해한 중금속을 Graphite furnance atomic absorption spectrophotometry로 정량하고 그 분포를 구하여 각 중금속의 정상치를 산정하여 중금속으로 인한 건강장해를 조기진단, 예방 및 관리를 하는데 도움을 주고자 본 조사를 실시하였으며 그 결과는 다음과 같다. 1.뇨중 중금속의 평균농도 1) Cr: 0.63±0.64㎍/ℓ 2) Cd: 1.68±1.50㎍/ℓ 3) Cu : 13.48±8.64㎍/ℓ 4) Mn : 7.33±8.78㎍/ℓ 5) Pb : 27.00±15.26㎍/ℓ 2.뇨중 중금속의 농도의 분포 1) Cr: 대수정규분포(왜도: -0.373, 첨도: -0.022, P>0.05) 2) Cd: 비정규분포(왜도: 1.202, 첨도: 0.579, P<0.05) 3) Cu: 대수정규분포(왜도: -0.016, 첨도: 0.301, P>0.05) 4) Mn: 비정규분포(왜도: 2.324, 첨도: 5.115, P<0.05) 5) Pb: 비정규분포(왜도: 0.671, 첨도: 0.541, P<0.05) 3.뇨중 크롬, 카드뮴, 구리, 망간, 연의 평균농도는 지역별로 유의한 차이가 있었으나(P<0.05), 연령별 차이는 없었다. 4.뇨중 구리와 뇨중 크롬이 뇨중 망간과 뇨중 카드뮴이 각각 정상관관계를 보였다(P<0.05, P<0.001). In order to provide basic data for early evaluation, prevention and management of health hazard caused by five heavy metals (chromium, cadmium, copper, manganese and lead), the author determined five heavy metals concentration in urine to 143 healthy matured nonsmoking females of 4 cities (Seoul, Pusan, Gheonan and Haman). The concentration of each heavy metal was measured by graphite furnace atomic absorption spectrometry. The urine sampling period was January 27 to February 6, 1994. The results were as follows. 1.The mean concentration of heavy metals in urine 1) Cr: 0.63±0.64㎍/ℓ 2) Cd: 1.68±1.50㎍/ℓ 3) Cu : 13.48±8.64㎍/ℓ 4) Mn : 7.33±8.78㎍/ℓ 5) Pb : 27.00±15.26㎍/ℓ 2.Tlle distribution of heavy metals concentration in urine 1) Cr : Lognormal distribution (Skewness : -0.373, Kurtosis : -0.022, P>0.05) 2) CD : Non-normal distribution (Skewness : 1.202, Kurtosis : 0.579, P<0.05) 3) Cu : Lognormal distribution (Skewness : -0.016, Kurtosis : 0.301, P>0.05) 4) Mn : Non-normal distribution (Skewness : 2.324, Kurtosis : 5.115, P<0.05) 5) Pb : Non-normal distributioon (Skewness : 0.671, Kurtosis : 0.541, P<0.05) 3.There were statistically significant differences in the concentrations in urine Cr, Cd, Cu, Mn and Pb by area(P<0.05). 4.Positive correlations were observed between correlations of Cr and Cu(P<0.001), Cu and Cr in urine(P<0.05). 5.The above results point out that the urinary heavy metals concentration of healthy adult women in urban area still hasn't reached the dangerous level. But if the degree of environmental pollution gets worse, the health hazard resulting from the overuse of heavy metal will increase. Therefore, more thoroughgoing measures to preserve our environment will be needed.