On the Strengthening Effects Affecting Tensile and Low Cycle Fatigue Properties of Low-Alloyed Seismic/Fire-Resistant Structural Steels

Jung‑Ho Sim,Tae‑Yeong Kim,Jun‑Yeon Kim,Chi‑Won Kim,Jun‑Ho Chung,Joonoh Moon,Chang‑Hoon Lee,Hyun‑Uk Hong 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.2

In the present study, low carbon ferritic and bainitic steels with different contents of Mo, Ti, and Nb were designed for bothseismic and fire-resistant applications. The microstructure of steels containing 0.3 wt% Mo–0.02 wt% Nb (‘A’ hereinafter)was mainly composed of bainite. By contrast, the microstructure of steels with 0.2 wt% Mo–0.13 wt% Ti (‘B’ hereinafter)consisted of ferrite with a high density of nano-sized (Ti,Mo)-rich MX precipitates. The results showed that the bainiticmicrostructure (‘A’ steel) was quite favorable to high-temperature strength and thermal stability. The yield strength of ‘A’ steelat both room and 600 °C temperatures increased consistently with increasing thermal exposure time (600 °C/200–1000 h),since the precipitation of NbC particles occurred while maintaining bainitic ferrite platelets with a high density of dislocationsduring exposure. In the ‘B’ steel, the formation of nano-sized (Ti,Mo)-rich MX particles was effective to impededislocation movement, leading to excellent plasticity (lower yield ratio) at room temperature. However, their contributionto precipitation hardening was not so much at 600 °C, as compared to the bainitic strengthening. During low cycle fatiguetests at room temperature, the main different feature between the two steels is that the ‘A’ steel showed cyclic softeningwhile cyclic hardening was evident in the ‘B’ steel. The bainitic microstructure showed a better fatigue life due to increasedductility manifested by cyclic softening, by which dislocation cell was developed.

Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions

Lee, Sang Choel,Han, Seung Hyeok,Li, Jin Ji,Lee, Sun Ha,Jung, Dong-Sub,Kwak, Seung-Jae,Kim, Seung Hye,Kim, Dong Ki,Yoo, Tae-Hyun,Kim, Jin Hyun,Chang, Se-Ho,Han, Dae Suk,Kang, Shin-Wook International Society of Nephrology 2009 Kidney international Vol.76 No.8

Heme oxygenase-1 (HO-1) is an anti-oxidant enzyme normally upregulated in response to oxidant injury. Here we determined the role of HO-1 in podocyte apoptosis in glomeruli of streptozotocin-treated rats and in immortalized mouse podocytes cultured in media containing normal or high glucose. HO-1 expression, its activity, the ratio of Bax/Bcl-2 protein, and active caspase-3 fragments were all significantly higher in isolated glomeruli of diabetic rats and in high glucose–treated podocytes. These increases were inhibited by zinc protoporphyrin treatment of the rats or by HO-1 siRNA treatment of the podocytes in culture. The number of apoptotic cells was also significantly increased in the glomeruli of diabetic rats and in high glucose–treated podocytes. Inhibition of HO-1 accentuated the increase in apoptotic cells both in vivo and in vitro. Our findings suggest that HO-1 expression protects against podocyte apoptosis under diabetic conditions.

혈액투석 환자의 가성 고칼륨혈증

최창렬,조형도,강태영,이준수,한호,정청일,이동규,유준호,한상웅,김호중 대한신장학회 2001 대한신장학회잡지 Vol.20 No.5

서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

신성고혈압 흰쥐에서 측뇌실내 Captopril이 Bradykinin의 중추승압효과에 미치는 영향

정태호,양민준,오승호,전제열,염철호,윤평진 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Effects of intracerebroventricular captopril on the central pressor response to bradykinin were examined in normotensive and 2-kidney, 1 clip (2KIC) Goldblatt hypertensive rats. The experiment was done under pentobarbital (50 ㎎/㎏. IP) anesthesia. Captopril (1 ㎎)and bradykinin (5 nmol) were administered into the right lateral cerebral ventricle, while arterial blood perssure and heart rate were continuously monitored throughout the experiment. Intracerebroventricular captopril did not affect the blood pressure within 10 minutes in both normotensive and 2KIC hypertensive rats, while it significantly augmented the central pressor response to bradykinin in the hypertensive rats. These observations suggest that an elevation in endogenous kinin levels is without effect on arterial pressure in normotensive and 2KIC hypertensive rats. However, the kallikreinkinin system in the central nervous system plays a role in the regulation of blood pressure, possibly maintaining the hypertension, in 2KIC hypertensive rats.

Pd(Ⅱ)이온과 Linear Poly(ethyleneimine)간에 생성되는 고분자-금속 착물의 구조와 성질에 관한 연구

한정호, 전은덕, 조태섭 영남대학교 기초과학연구소 2000 基礎科學硏究 Vol.20 No.-

Pd(II) metal ion has attracted interest of many researchers because of its potential applications and of its similarity and difference in chemical properties. In this study, complex formation of Pd(II) metal ion with polymeric amine ligand namely, linear poly(ethyleneimine)(LPEI), was investigated utilizing spectroscopic and potentiometric methods as well as elementary analysis. From UV/VIS spectroscopic study, complexation of LEPI to Pd(II) ion exhibit an absorption band at 347nm at the low mole ratio (below 2.0). This species can be understood either as the binuclear complex bridged by chloride ions or a complex of Pd(II) ion with three chloride ions and an amine group. At the high mixing ratio, absorption spectrum centered at 300nm was apparent, which is due to the complexation of LPEI to the Pd(II) ion. Mole ratio analysis for the LPEI-Pd(II) system revealed that complex formation was most stable at the LPEI ratio of 4.0 relative to metal ion. This result was confirmed by elementary analysis. From the potentiometric titration, successive and overall stability constants were measured and the results were analyzed by a modified Bjerrum method.

도시내 불량주거지 정비방안에 관한 연구 : A Case Study of Seo-gu in Pusan 부산광역시 서구를 중심으로

정태철,이성호 釜山大學校 都市問題硏究所 1999 都市硏究報 Vol.8 No.-

This study starts from recognizing the necessary of urban environmental improvement and purposes to prepose a new improvement scheme of urban districts are serious physical housing problem. For the purpose of archiving these, I did the case study. The results of this study are summarized as follows. 1. The improvement plans of CBD are to do development in the neighborhood of station. The district of Chung-moo-dong is near from CBD in Pusan and takes charge of commercial business and sales. So in this district, these parts has been to strengthen and residential areas have to be moved around CBD. 2. The improvement plans of residential areas must be progressed toward making the best use of a local specific character. Seo-gu is located in hilly sections in Pusan. For that reason, the application of a typical method like a high-rise apartment building raise serious damages. So I insist on the low-density development method to use a slope advantage. For setting about this plan, local government must have enough finacial power. So I suggest a device for supporting these subjects partially. This is 'Transfer of Development Right'. Finally when the harmony between public-interest and self-interest is achieved, the urban residential areas can be improved systematically and problems will be settled satisfactorily.

갑상샘 유두암과 혼재하여 발견된 편평세포암 1예

김호수,정태식,정정화,김수경,이상민,정순일,함종렬 영남대학교 의과대학 2011 Yeungnam University Journal of Medicine Vol.28 No.2

The occurrence of a mixed tumor containing papillary thyroid carcinoma (PTC) and primary squamous-cell carcinoma (SCC) is rare because there is no squamous epithelium in the thyroid gland. Reported herein is a 30-year-old female with mixed PTC and primary SCC of the thyroid presented as thyroid incidentaloma. Fine-needle aspiration biopsy of the thyroid nodule revealed the presence of malignant thyroid cells. The histopathological examination following total thyroidectomy yielded two mixed, morphologically distinct histotypes that included PTC and SCC. After total thyroidectomy, the patient underwent radioactive iodine therapy. No recurrence or metastasis occurred during the 20-month follow-up period after the operation.

공공부문 조직과 민간기업 조직의 직무만족도 비교분석 : 한국노동패널연구(KLIPS)자료를 중심으로

정광호,김태일 한국정책학회 2003 韓國政策學會報 Vol.12 No.3

그동안 국내에서 직무만족도에 관한 연구는 사회과학 여러 분야에서 이루어져 왔지만 공공부문과 민간부문사이의 직무만족도가 다를 것이라는 가설은 체계적으로 연구되지 못했다. 특히 대부분의 연구들은 횡단면 자료(cross-sectional data)를 가지고 분석했기 때문에 지난 1997년 경제위기 이후 직무만족도의 종단면적 추이를 분석하는데 한계가 있었다. 이에 본 연구는 기존의 연구와 달리 지난 1998년 이후 매년 조사되고 있는 한국노동패털자료(Korea Labor and Income Panel Study)를 이용하여 공공 및 민간부문간의 직무만족도의 차이에 대한 패널분석을 시도하고 있다. 본 연구의 분석결과 지난 1998년부터 2001년까지 정부기관에 종사자들의 직무만족도가 민간기업종사다들보다 높음을 보여준다. 특히 취업안정성 만족도에서 가장 큰 차이가 발견되었다. 한편 보수만족도의 경우 지난 1998년부터 2000년까지는 양 부문에서 유의미한 차이가 없었지만 2001년의 경우 민간부문에 비하여 공공부문의 보수만족도가 높아지고 있다. 추가로 본 연구는 교육변수와 성별변수에 따라 양 부문간의 직무만족도의 차이를 분석하고 있다. 특히 보수만족도와 복지후생만족도의 경우 공공부문의 고졸집단 만족도가 공공부문 및 민간부문의 대졸집단 만족도보다 높았다. 또한 직업 안정성, 직무내용, 그리고 복지후생 만족도의 경우 공공부문의 남성집단 만족도가 민간부문 여성집단의 만족도보다 높았다. 이 연구결과는 일반적으로 대졸집단이 고졸집단보다 그리고 여성이 남성보다 높은 직무만족도를 보인다는 사실과 상반된 것이다. 이것은 아마도 민간조직과 달리 공공조직이 가진 독특한 특성과 관련이 있어 보인다. Pervious studies have tended to neglect a hypothesis of differences in job satisfaction between public and private organization. Because they examined the hypothesis with a cross-sectional data, they have not showed a trend of job satisfaction since the 1997 economic crisis in South Korea. Unlike prior research, this study explores the longitudinal differences in job satisfaction between these two types of organizations with the Korean Labor & Income Study dat. This study shows that the level of job satisfaction in public organizations was higher difference in the level of satisfaction of job stability in the same period. While there was little difference of wage satisfaction between them between 1998 and 2000, the level of wage satisfaction in public organizations was higher than that in private organizations in 2001. In addition, this study examines differences in job satisfaction in terms of education and gender. In public organization, those with high school degree have a higher level of satisfaction in wage and welfare than those with college degree. In the case of job stability, job contents and occupational welfare, male group in public organizations has a higher level of satisfaction than female group in private organizations These results contrast with the following two facts: (1) in general, the level of job satisfaction for those with college degree is higher than that for those with high school degree or no high school degree; and (2) the level of job satisfaction for female group is higher than that for male group. It appears to be related to the unique characteristics of public organizations.