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허혈성 뇌혈관 질환환자의 국소뇌혈류와 그 임상적용에 관한 연구
이기홍,김동근,임영진,김태성,김국기,이봉암,임언 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.5
A reliable method of measuring r-CSF should give further insight into the pathophysiology of ischemic symptome and might facilitate decisions regarding patient managment. In order to study the correlation between r-CBF value and ischemic cerebrovascular disease, 80 patients who were admitted to the Department of Neurosurgery, Kyung Hee University Hospital, between January, 1983 and December, 1986 were evaluated by 133-Xenon inhalation method. The results were as follows : 1) There was significant decrease of CBF in patients with ischemic cerebrovascular disease than CBF of control group. 2) There was significant decrease of CBF in patients of completed stroke than TIA or RIND patient. 3) 67.5% of patients showed more decreased hemispheric value on the symptomatic side than that of opposite side. 4) r-CBF was decreased significantly in the region corresponding to each vascular territory infarction. 5) There was significantly lower CBF in patient with hematocrit in range 47 or more than in patient with hematocrit in the range 36~46. 6) Group of patients with progressing neurological manifestation showed significantly decreased CBF than of group of patients improved. It is suggested that r-CBF measurement may be helpful for evaluation and managment of the patient with ischemic cerebro-vascular disease.
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병원성 대장균의 이열성독소 검사를 위한 V-ET RPLA법과 ELISA법의 비교 및 혈청균과 독소생성의 관련성 연구
이기홍 건국대학교 1991 대학원 학술논문집 Vol.34 No.-
The V-ET RPLA and ELISA techniques were compared for the dection of heat-labile enterotoxin of Escherichia coli. E.coli strains, 1,568 in number, were isolated from 2,617 stool specimens collected from pediatric patients attending 7 clinics or hospitals in Seoul. Among the isolates, 95(6.1%) were either enterotoxigenic, enteroinvasive or enteropathogenic E.coli serologically. The determined results by Vibrio cholerae E.coli enterotoxin reversed passive latex agglutination (V-ETRPLA) and enzyme-linked immunosorbent assay(ELISA) were as follows.: 1.The detection rate of heat-labile enterotoxin by V-ET RPLA and ELISA were 9.5 per cent and 20.0 per cent respectively, however these two rates showed no signficant difference(p>0.05). 2.In order to compare the power of detecting heat-labile enterotoxin, the same 55 E.coli isolates were tested by V-ET RPLA and ELISA method. ELISA showed the detection rate of 20.0 per cent than the rate of 16.4 per cent by V-ET RPLA, but there was no significant difference between V-ET RPLA, but there was no significant difference between V-ET RPLA and ELISA methods(p>0.05). 3.The size of the proportion of strains producing heat-labile enterotoxin in enterotoxigenic E.cdi(ETEC) Compared to enteropathogenic E.coli(EPEC) indicate no relationship(p>0.05).
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