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김호중,조은영,오원기,임정란 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.5
난소내배엽동종양은 매우 드물고 예후가 불량한 악성종양이지만 적절한 수술과 병용화학요법, 그리고 AFP의 추적검사등으로 상당히 향상된 예후를 보이고 있다. 최근 저자들은 양성기형종이 동반된 난소내배엽동종양 1례를 경험하였기에 문헌적 고찰과 함께 보고하는 바이다. The endometrial sinus tumor is a rare but highly malignant neoplasm seen mainly in children and young adults. First Schiller described as a tumor of mesonephric origin in 1939, it was subsequently recognized by Teilum as an endodermal sinus tumor. Endodermal sinus tumors are frequently seen in combination with other forms of germ cell tumor, including dysgerminoma, mature teratoma, immature teratoma, embryonal carcinoma, and less frequently choriocarcinoma. In this report, a case of endodermal sinus tumor in combination with mature teratoma is presented with a brief review of the literatures.
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김호중,박세정,박수현,박지원,장봉순,이춘기,염진섭 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.2
Purpose: To assess the association between frailty and osteoporotic vertebral compression fracture (OVCF) and to evaluate the relationship between numbers of OVCFs and frailty. Materials and Methods: We enrolled 760 subjects, including 59 patients (with OVCF) and 701 controls (without OVCF). Successfulmatching provided 56 patient-control pairs. We analyzed principal clinical and demographic information, which included sex, age, height, weight, body mass index (BMI), variable frailty phenotypes, and Oswestry Disability Index (ODI) and EuroQol 5-dimensionquestionnaire (EQ-5D) scores. The association between frailty and OVCF was ascertained. In addition, the degrees of disability and quality of life attributable to frailty were determined. Results: The prevalence of frailty was significantly higher in the OVCF group than in the control group (p<0.001). Most of the frailtyphenotypes, such as exhaustion, physical inactivity, slowness, and handgrip strength, were also significantly observed in the OVCF group. Within the OVCF group, the participants with frailty had significantly higher disability and lower quality of life than those in a robust state (p<0.001 for ODI and EQ-5D). In addition, the multivariate logistic regression analysis demonstrated that the patients with low BMI [odds ratio (OR)=0.704; 95% confidence interval (CI), 0.543−0.913] and ≥3 fractures (OR=9.213; 95% CI, 1.529−55.501) within the OVCF group were associated with higher odds of frailty. Conclusion: The present study showed significant relationships between frailty and OVCF, severity of symptoms, and disability induced by OVCF. Furthermore, frailty could be a causal and/or resulting factor of OVCFs.
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