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금속매염제인 초산구리의 세포독성에 대한 자귀나무잎 추출물의 보호 효과
정정화,임요섭,서영미 한국환경보건학회 2019 한국환경보건학회지 Vol.45 No.5
Objectives: This study assessed the cytotoxicity of the metallic mordant cupric acetate (CA) and the protective effect of Albizzia julibrissin (AJ) leaf extract on CA-induced cytotoxicity in NIH3T3 fibroblasts. Methods: For this study, cell viability and antioxidative effects such as the inhibitory activity of lipid peroxidation (LP) and superoxide anion-radical (SAR) scavenging activity were assessed. Results: CA significantly decreased cell viability in a dose-dependent manner, and the XTT50 value was measured as 55.0 µM of CA. The cytotoxicity of CA was determined as highly toxic by Borenfreund and Puerner’s toxic criteria. The catalase antioxidant significantly increased cell viability diminished by CA-induced cytotoxicity in these cultures. Regarding the protective effect of AJ leaf extract on CA-induced cytotoxicity, AJ leaf extract remarkably increased the SAR scavenging ability and the inhibitory ability of LP. From these findings, it is suggested that oxidative stress is involved in the cytotoxicity of CA, and AJ leaf extract effectively protected CA-induced cytotoxicity via antioxidative effects. Conclusions: Natural resources like AJ leaf extract may be a putative therapeutic agent for treatment or alleviation of the toxicity induced by CA metallic mordant.
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농촌여성노인의 생활만족도에 미치는 영향요인에 관한 연구 -K지역에 거주하는 농촌여성노인을 중심으로-
정정화,이재모 사단법인 인문사회과학기술융합학회 2017 예술인문사회융합멀티미디어논문지 Vol.7 No.3
The study aims to discuss ways of practicing social welfare so that the elderly in the countryside may feel better life satisfaction by identifying factors behind life satisfaction of elderly women in the countryside. The study involved 196 elderly women living in local area “K” and collected data from May 1 2016 through June 30, which were put under analysis by using technological statistics and hierarchical regressions analysis. As a result, it turned out that such factors as gender, monthly income, depression and ego-integrity influence life satisfaction of elderly women in the countryside. Though both depression and ego-integrity were significant on statistical terms, a close look at comparison through the use of standardized regression coefficient shows that ego-integrity (β=18.73.p〈.01) is more significant than sense of isolation (β=.07,p〈.001) and depression (β=.10,p〈.01). Thus, it is important to explore feasible approach to the role of ego-integrity in life satisfaction of elderly women in the countryside. 본 연구는 농촌여성노인들의 생활만족에 영향을 미치는 요인을 파악하여, 농촌여성노인들의 생활만족도를 향상시킬 수 있는 사회복지 실천 방안을 논의하고자 하였다. 본 연구의 대상은 k지역에 거주하는 농촌여성노인 196명을 대상으로 2016년 5월 1일부터 2016년 6월 30일까지 이루어졌다. 본 연구결과, 농촌여성노인의 생활만족도에 미치 요인을 알아보기 위하여 위계적 회귀분석을 한 결과를 살펴보면, 농촌여성노인의 생활만족도에는 자아통합감(β= .03, p〈.001), 사회적 고립감((β= .07, p〈.001), 우울(β= .13, p〈.001)과 인구사회학적 변수인 건강상태(β= .87, p〈.001)가 영향을 미치는 것으로 나타났다. 표준화된 회귀계수를 비교하여 볼 때, 자아통합감이 사회적 고립감, 우울, 건강상태에 비해 높은 영향력을 갖는 것으로 보인다. 최종 회귀모형의 설명력은 .62%이었다. 따라서 농촌여성노인의 생활만족도에는 자아통합감이 큰 영향력을 가지고 있음을 알 수 있었다. 따라서 농촌여성노인 생활만족도에 있어서 자아통합감의 역할에 대한 실천적 접근 방안을 모색할 필요가 있다.
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정정화,조인수 大邱大學校 師範大學 附設 敎育硏究所 2009 學校敎育硏究 Vol.5 No.1
본 연구는 초등학교에 근무하는 특수학급 교사들의 특수교육 보조원 활용실태를 알아보는데 연구의 주안점을 두었다. 구체적인 연구목적은 첫째, 특수 교육 보조원 활용성과에 관한 초등학교 특수학급 교사의 인식수준을 밝히고 둘째, 초등학교 특수학급 교사들의 특수교육 보조원 활용실태를 밝히는데 있다. 얻어진 결론은 초등학교 특수학급 교사들은 특수교육보조원 제도 운영에 긍정적인 인식을 갖고 있고, 통합교육 교육을 위한 바람직한 제도이며, 학생 및 학부모 모두에게 긍정적인 효과를 내며 특수교육에 질적인 변화를 가져온다고 인식하고 있다. 활용실태 면에서 수업협의, 통합 학급 교사들과의 갈등해소, 팀 체제의 구성, 특수교육보조원에 대한 책임한계, 자질 및 역할 수행에 대한 만족도 차이와 직무연수, 선발ㆍ배치 관리에 있어 학교의 자율성, 학생 인원수에 따른 보조원수 조정, 행ㆍ재정적 지원대책 등을 분석하였다. 구체적인 인식과 실태분석에서 제시된 내용들은 특수교육 보조원의 효율적 활용방안에 기초자료를 제공해 줄 수 있을 것이다. The purposes of this study is to examine the perception of teachers for special classes in elementary schools on the outcomes of the utilization of paraprofessionals for students with disabilities, the actual use of those paraprofessionals by teachers for the use of paraprofessionals in a bid to suggest some reform measures about how to take advantage of paraprofessionals. The subjects of this study were teachers who are in charge of special classes in 60 elementary schools in Daegu. The findings of the study are as follows; First, the elementary school teachers for special classes took a positive view of the paraprofessional system. They thought that the employment of paraprofessionals contributed to laying the solid groundwork for inclusive education, and that educational services provided by them brought a change to the quality of special education. Second, after paraprofessionals started to work, students with disabilities had more opportunities to receive inclusive education as they helped them when they got around or needed another help. The teachers had a discussion with them in advance about instruction, which served to offer more practical inclusive education. To let the paraprofessional system take root, however, there should be mutual confidence between the teachers and paraprofessionals, and management and evaluation criteria should be clarified.
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정정화,심기남,권경주,나선경,윤혜원,송도경,강석형 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1
Double pylorus is one of the rare anomalies of gastrointestinal tract, which have an accessory canal connecting the distal stomach to the duodenal bulb. The majority of the cases is thought to be acquired lesions from ulcer disease except some congenital cases. We report a case of a 77 year-old male who was visited the hospital because of the melena and diagnosed double pylorus. The relevant literatures on subject were reviewed.
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첨단 생산기술, 관리회계정보시스템 변경과 관리회계 정보특성
정정화,최종민 한국산업경영학회 2017 한국산업경영학회 발표논문집 Vol.2017 No.1
Based on the complementarity theory, this study empirically investigated both the impact of advanced manufacturing technology(AMT) on the changes of management accounting information systems (MAIS) and the changed characteristics of management accounting information(MAI) incurred by MAIS changes. This study also examined the influence of MAI characteristics on information satisfaction and system usage as well as the effects of information satisfaction and system usage on organizational performance. The results showed that AMT has a significant impact on the partial changes or replacement of MAIS. It was also found that AMT does not affect MAI characteristics. The empirical results of this study represent that the information integration and information scope of MAIS have a positive impact on information satisfaction and MAIS usage, and these satisfaction and usage lead to the improvement of departmental performance.
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