서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

입원 중인 베트남 참전 군인의 삶의 만족도와 관련된 요인

김애리,박종,김율,노희송,박광희,김은숙,김형철,홍강식,류소연,강명근,김기순 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Background and Objectives: The aim of the study was to identify the factors associated with life satisfaction of hospitalized Vietnam veterans. Material and Methods: The data were collected from 200 hospitalized Vietnam veterans of 5 veterans hospitals in Korea from September 13 to 23, 2004. Information of general characteristics, health behavior, disease history, family function, depression and life satisfaction were collected by structured questionnaire. Results: The mean of life satisfaction was 21.48(±6.03), and the mean of depression was 53.10(±9.64). The prevalence of depression was mild depression 24.0%, moderate depression 43.5% and severe depression 25.0%. Depression was associated with life satisfaction and depression was higher, life satisfaction was lower. Family function and age were positively associated with life satisfaction, Conclusion: Life satisfaction was affected by depression and family function in hospitalized Vietnam veterans. Therefore, it was thought that psychosocial approaches such as improve depression and family function in care of hospitalized Vietnam veterans is required.

추적조사를 중심으로 한 腰椎間板脫出症에 대한 蜈蚣藥鍼의 臨床的 硏究

최회강,소기숙,고강훈,박소영,김성남,이종덕,원경숙,문형철,김성철 大韓鍼灸學會 2003 대한침구의학회지 Vol.20 No.3

Objective : This study is performed for the purpose of examining the efficacy of the scolopendrid(Scolopendra morsitans L) which has been to low back pain as a folk remedy. Methods & Results : Seventy patints with H.I.V.D. treated with the scolopendrid aquacupuncture and examined 4 tests; D.I.T.I., physical test, Oswestry disability index, and self-conscious pain rate were studied. And we follow up after discharge, we evaluated the present state and recovery period. Or we evaluated by herniated type and duration of onset. There was 58~97% of efficacy rate in each tests. Moreover, statistically valuable change in all 7D.I.T.I. points and in disability index and in self-conscious pain rate was showed. Conclusion : The scolopendrid aquacupuncture is possible to be effective terating the H.I.V.D patients. so we suggest the possibility using this new remedy to the H.I.V.D. patients.

A case of ectopic opening of common bile duct in duodenal bulb

( Ju Ri Kim ),( Hyun Cheol Koo ),( Ji Woong Jang ),( So Hee Chung ),( Min Kyu Kang ),( Jin Young Kim ),( Dong-kyu Lee ),( Jun Hyung Park ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Ectopic opening of common bile duct (CBD) in duodenal bulb is very rare, and it can be missed at endoscopy because of small size of the orifice that lacks typical feature of major duodenal papilla and duodenal deformity that makes endoscopic approach difficult. However, it should not be overlookedbecause of critical complications such as recurrent duodenal ulcer or cholangitis. Here we report one case of ectopic opening of CBD in duodenal bulb which was managed with endoscopic retrograde biliary drainage (ERBD) through endoscopic retrograde cholangiopancreatography (ERCP). The patient visited us for fever and abdominal pain. There were some significant findings in studies, which included stricture of duodenal bulb with ulcer and one loose slit-like opening in duodenoscopy, in addition to the tapered distal CBD with dilated proximal part in abdominal CT and ERCP. He treated with two times of ERBD insertion which improved duodenal ulcer and cholangitis, and discharged without any biliary related symptom. The common feature of ectopic opening of CBD isknown to be the absence of normal sphincteric structure. Since it allows free movement of bile and duodenal contents between CBD and duodenal bulb without sphincteric control, this disease frequently accompanies recurrent duodenal ulcer and cholangitis that can cause irreversible deformity. Another is the tapered distal CBD (so-called “hook shaped CBD” in several reports) with dilated proximal part in imaging studies. This is assumed to contribute to bile stasis that promotes bacterial growth or lithogeniccharacteristics of bile, which can lead to biliary disease. These complications can be managed with conservative way, but sometimes need surgical procedure, then, these situations need further accurate diagnosis because of risk for accidental biliary tract injury during surgery due to abnormal location of bile duct orifice. In conclusion, if we encounter recurrent duodenal ulcer or cholangitis in the field, we have to consider the possibility of ectopic opening of CBD.

일측성 질폐쇄 및 동측 신장 무발생을 동반한 중복자궁 2예

윤일영,여소진,김형문,김정식,김태희,이해혁,남계현,이권해,김준모,김민의 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Uterus didelphys with unilateral obstructed hemivagina and ipsilateral renal agenesis usually presents after menarch with progressive abdominal pain during menses secondary to hematocolpos, and indeed a very rare congenital anomaly due to Mullerian duct malformation. An accurate and prompt diagnosis is of importance to permit treatment and to assure the future fertility of the patient. Pelvic ultrasound, physical examination and pelvic MRI established a diagnosis of hematometracolpos secondary to uterus didelphys with unilateral imperforate hemivagina. An incision in the vaginal septum allowed drainage of the hematocolpos, providing relief of the patients symptoms. We report two case of uterus didelphys with obstructed hemivagina with brief review of the literature.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

한국에서 메스암페타민 남용 또는 의존 환자의 인격장애에 관한 연구

김소영,권성민,조성남,권도훈,강병조,김형태 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.2

연구 목적 : 메스암페타민 남용 또는 의존이 없는 군과 있는 군 사이의 인격장애의 유병율을 알아보고, 메스암페타민 남용 또는 의존군에서 동반 인격장애가 그들의 전반적 기능 및 일반적 특성에 어떠한 영향을 미치는지 알아보고자 하였다. 방 법 : 대상은 정상대조군에서 메스암페타민 남용 또는 의존이 없는 50명과 정신병원에 입원한 메스암페타민 남용 또는 의존환자 50명이었다. 메스암페타민 남용과 전반적 기능에 대한 평가는 DSM-Ⅳ에 의거하였고, 인격장애를 평가하기 위해 대상군 모두에서 PDQ-4+를 시행하였다. 결 과 : 정상대조군은 34%에서 적어도 1개 이상의 인격장애를 나타내었으며, 한 사람 당 평균 3.94개였다. 메스암페타민 남용 또는 의존군은 64%에서 적어도 1개 이상의 인격장애를 보였으며, 한 환자 당 평균 4.72개였다. 메스암페타민 남용 또는 의존군에서 동반 인격장애의 유무는 시작 연령, 사용 용량, 그리고 입원 또는 구치 횟수와는 관련성이 없는 것으로 나타났으나, 3개 이상의 동반 인격장애를 가질 경우, 그렇지 않은 군에 비해 전반적 기능이 떨어졌다. 결 론 : 본 연구 결과, 우리나라에서도 일반인에 비해 물질사용장애 환자에서 인격장애를 동반할 가능성이 높으며, 물질사용장애 환자 중에서도 인격장애를 동반한 군이 그렇지 않은 군에 비해 전반적으로 기능이 떨어진다는 결론이 가능하게 되었다. Objectives : The purpose of this study was to examine the prevalence of personality disorders between normal control group and hospitalized methamphetamine abuse or dependent patients and, among the latter, the influence of comorbid personality disorder on their global assesment function and general characteristics. Methods : Subjects were 50 non-methamphetamine abuse or dependent persons in the general population group and 50 methamphetamine abuse or dependent patients admitted to the psychiatric hospital. Methamphetamine abuse or dependence and the global assesment function were diagnosed according to DSM-Ⅳ, and the presence of personality disorder was assessed with the PDQ-4+. Results : In the normal control group, 34% of subjects had at least one personality disorder and the average number of personality disorder was 3.94 per person. In the methamphetamine abuse or dependent group, 64% of the patients had at least one personality disorder and the average number .of personality disorder was 4.72 per patient. The presence of comorbid personality disorder were not associated with onset age, use dosage and the number of admission or arrest among the methamphetamine abuse or dependent group. But, when methamphetamine abuse or dependent patients had more than three personality disorders, the global assessment function was impaired. Conclusion : In our study, substance use disorder patients had the higher possibility of comorbid personality disorder in Korea, and among substance use disorder patients, those with comorbid personality disorders were associated with the greater global impairment.

랫드에서 인체 재조합 적혈구 조혈인자, rHuEPO의 13주 정맥투여 아만성독성에 관한 연구

김형식,곽승준,천선아,박현선,한하수,임소영,안미영,김원배,김병문,안병옥,홍성렬,이병무 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

A recombinant human erythropoietin (rHuEPO) was administered intravenously at dosage levels of 0, 100, 500, and 2500 IU/㎏/day for a period of 13 weeks. There were no observed clinical signs and deaths related to treatment in all groups tested. Decreases in body weight gain and food consumption were observed only in males of 2,500 IU/㎏ group after 2 weeks. In hematological parameters, erythrocyte content, hematocrit values and hemoglobin concentration were dose-dependently increased in rHuEPO treated groups. The ratio between kidney weight and whole body weight was significantly increased in females of 500 and 2,500 IU/㎏ groups. The spleen weight was also increased in both sexes of 500 and 2,500 IU/㎏ groups. However, the absolute weight change of other organs was not observed. In histopathological examinations, the renal tubular basophilia was observed only in males and females of 2,500 IU/㎏ groups. From these results, it is concluded that the no-observed adverse effect level(NOAEL) of rHuEPO is 100 IU/㎏ in rats in the present study.

중등영어 교육에서의 발음교육의 문제점과 그 개선책

김형수,소화경,이형팔,황규상 전주대학교 교육문제연구소 2001 敎育論叢 Vol.16 No.-

都市가스取扱시 災害防止對策

김형소 三陟大學校 1997 論文集 Vol.30 No.2

In recent times the accidents of LPG, LNG, such as compressed gases were increased in number every year in our country. We Should have to use carefully them, and scientific method with safety control in the variety of places. Here I study the transformation in technology of their sientific data in the pubulished literature : how to good treat them? how to work apparatus?, and I emphasized the importance of distribution to the educational dissemination movement to have disaster prevention to the user and related to educational matter.