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      • Kartagener's Syndrome의 1예

        홍순표,정복기,조건국 朝鮮大學校 附設 醫學硏究所 1983 The Medical Journal of Chosun University Vol.8 No.1

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        Kartagener's syndrome is a rare disease, characterized by situs inversus, sinusitis, dextrocardia and bronchiectasis. This is a report of a rare case of kartagener's syndrome in 20-year-old-male whose chief complaint was purulent sputum, rhinorrhea, & exertional dyspnea. Chest P-A view revealed the dextrocardia and the magenblase in the right subphrenic area, suggesting situs inversus totalis. Multiple small cystic radielu-concies are also seen in lower halves of both thorax, suggesting bronchiectasis. P.N.S view revealed the homogenous increase-d density in all sinuses, tut didn't clear bony destruction. Bronchogram revealed the saccular and tubular dilation of the segmental bronchi in all bronchi, Particularly in the right lower lobe bronchus. EKG finding was alternation of voltage, right atrial hypertrophy and dextrocardia.

      • 금연 프로그램이 청소년 흡연자의 흡연에 대한 지식과 태도에 미치는 효과

        이강오,나덕미,김지은 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

        The purpose of this study is to define some effects of cessation program which is devoted to youth smokers, on their knowledge and attitude change to smoking. Raw data was derived from 74 high school students those who were attended at a quasi-experimental research design. Some statistical procedures such as frequency, mean & standard deviation, paired t test were applied to the questionnaire data. There was an apparent change in knowledge level and attitude against smoking between pre and post cessation program. It is concluded that some kinds of smoking cessation program are efficient ways to be non-smokers especially for the adolescents, because they can induce some positive changes in knowledge and attitude toward smoking. Hopefully, if it is possible to develop any cessation program which is simultaneously considering school, peer group, and home environment, the utility would be multiplied.

      • 혈액투석환자의 혈액투석 관련지식과 환자역할행위 이행과의 관계

        나덕미,이강오,송은숙 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

        The purpose of this study was to clarify the relationship between the knowledge of hemodialysis and the compliance of patient role behavior in hemodialysis patients. This study was descriptive correlational study. Data were collected by questionnaire from 122 hemodialysis patients. Data were collected by questionnaire from 122 hemodialysis patients. In knowledge about hemodialysis, there were significant difference in age, education level, marital status, paying for the treatment and number of oral medication. In compliance of patient role behavior, there were significant difference in age, education level and paying for the treatment. The correlation between knowledge about hemodialysis and compliance of patient role behavior was statistically significant (r=.354, p=0.000). It is proved the research hypothesis, that is, 'statistically difference in the knowledge of hemodialysis and the compliance of patient role behaviour'. Based upon these findings, it was relevant that the knowledge of hemodialysis itself can promote the compliance of patient role behaviour in hemodialysis patients who are characterized by long time period treatment. As a result, it is very important to increase patients' knowledge of hemodialysis by learning in order to get a great treatment efficiency in case of hemodialysis patients.

      • 난소암종에서 원발성과 전이성의 감별

        이미자,박정훈,전호종 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

        Background and Objectives: Histologic differentiation of primary ovarian carcinoma from metastatic carcinoma to the ovary may be difficult. We investigated to discriminate between primary and metastatic ovarian carcinoma by immunohistochemistry. Materials and Method: Ire evaluated cytokeratin (CK) 7, CK20, CK18, and carcinoombrvonic antigen (CEA) expression In 20 ovarian adenocarcinomas (7 serous, mucinous. 2 endomotrioid, and 7 metastatic), 10 gastric adenocarcinomas and 10 colonic adenocarcinomas. Results: CK7 expression was demonstrated in all serous and 3 out of 4 mucinous adenocarcinoma, and 1 out of 10 each gastric and colonic adenocarcinoma. CK20 expression was seen in 4 out of 10 cases of colonic adenocarcinoma and 3 out of 7 cases of metastatic ovarian carcinoma. But, all primary ovarian carcinoma and gastric adenocarcinoma were negative for CK20 except for focal positivity in only 1 ovarian mucinous adenocarcinoma. CK18 expression may not be helpful to differentiate the primary or metastatic carcinoma because all cases examined were positive for CK18 except for 1 ovarian mucinous carcinoma. CEA expression was negative for all serous and endometrioid adenocarcinoma, but was positive for the vast majority of mucinous type, metastatic ovarian carcinoma, gastric and colonic adenocarcinoma. Conclusion: Immunohistochemical study for CK7 and CK20 may be helpful in differential diagnosis between primary and metastatic ovarian carcinoma. Also, imrnunostaining for CEA may be a value on differential diagnosis of mucinous and nonrnucinous (serous and endomerioid) ovarian carcinomas.

      • 외상성 경막하수종 환아에서 조기 수술의 유용성

        김병욱,이승명,김석원,김현성,신호 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

        Background and Objectives: This study was performed to evaluate the usefulness of early operation in children with traumatic subdural hygroma. Materials and Methods: The subjects were eleven patients (Glasgow coma scale (GCS) score was below 10 and age was below 10 years old) who developed subdural hygroma after trauma between January 2000 to December 2002. Subduroperitoneal shunt was performed in one group and not performed in the other group. We analyzed the GCS score on admission and at 1 year after operation. Overall clinical results were evaluated retrospectively. Results: Patients who underwent operation exhibited higher GCS scores at 1 year after trauma compared to those in the patients who were treated by conservative therapy (p<0. 05). Conclusion: The early operation could be an effective treatment to children with subdural hygroma who showed delayed improvement of consciousness and to patients with hygroma that didn't decrease or was above moderate amount.

      • 안면부, 유방 및 상완부에 발생한 홍반성 루푸스 지방층염 1예

        송유근,손두식,명형준,이현정,임중규,김순호,김윤아 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Lupus erythematous panniculitis is a chronic inflammatory disease of subcutaneous fat that occurs in 2-3% of patients with systemic lupus erythematosus. Lupus erythematous panniculitis typically presents with firm, indurated subcutaneous nodules or plaques commonly developed in proximal extremities, trunks, head and neck. Face, breast and upper extremities involvement with lupus erythematous panniculitis has been infrequently reported. We report a case of lupus erythematous panniculitis developed in a 27-year-old female confirmed by histologic features and laboratory findings.

      • Ticlopidine 복용후 발생한 심한 호중성백혈구 감소증이 G-CSF투여 후 빠른 회복을 보인 1예

        강지은,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Ticlopidine is a antiplatelet agent used to prevent acute thromboembolic artery occlusion. It is a thienopyridine derivative that inhibits platelet aggregation through an adenosine 5'-diphosphate(ADP) -dependant pathway. Ticlopidine has been associated with serious hematologic effects. Neutropenia has been seen with ticlopidine with an incidence of 2.1% and 0.8% incidence of severe neutropenia. We reported here, one case of severe neutropenia developed after use of ticlopidino. Patient suffered from an acute cerebral infarction. Hr developed neutropenia 1 year after treatment with 100 mg ~ 500 mg/daily. After stopping riclopidine, he was recieved Granulocyte Colony Stimulating Factor (G-CSF). In two days after G-CSF administration, neutropenia was quickly improved.

      • 선천성 승모판폐쇄부전증 수술 후 발생한 승모판 전엽의 수축기 전방 변위 : (Systolic anterior motion of AML : SAM) - 1예보고

        이석기,김상규 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Congenital mitral regurgitation is combined with the other congenital heart disease or alone. This conditions needs to correct the dilated annulus or valve, and then did the valve replacement or repair. We reported a 10-year-old girl with congenital mitral regurgitation (grade III) had undergone the both unsymmetrical commissural plication, but postoperative left ventricular outflow tract obstruction(LVOTO) was developed by the systolic anterior motion (SAM) of Anterior mitral leaflet. In reoperation, LVOTO was relieved by resection of posterior leaflet and annuloplasty. During follow up period of 5 years, she has been well done without mitral regurgitation and stenosi by echocardiography.

      • 대장에 발생한 샘암종에서 MUC1과 MUC2 점소 발현의 의의

        이윤경,이주호,이용,심재영,박정훈,오수섭,박진실,기근홍 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Background : Mucins possess the unique function of protecting and lubricating the epithelial surface and other important functions such as call growth, direct implication in the fetal development, the epithelial renewal and differentiation, the epithelial integrity, carcinogenesis, immune regulation, cellular adhesion and metastasis. Purpose : This study was done to provide the significance of alteration of MUC1 and MUC2 expression in colorectal adenocarcinoma, A series of 131 colorectal adenocarcinomas including 11 mucinous carcinomas were screened immunohistochemically for their expression of MUCI and MUC2, Materials and mehtods : Of 131 carcinomas, 76 (58,5%) were MUCI positive and 91 (68, 9%) were MUC2 positive, In normal colonic goblet cells, MUCl was not expressed but MUC2 was expressed in cytoplasm, Conclusion There were up-regulation of MUCI and down-regulation of MUC2 in colorectal carcinomas, The frequency of MUC2 positivity according to differentiation was statistically reliable. (p=0.0001)

      • 진행성 위암에 동반된 위 칸디다증 1예

        이두영,김성호,선제형,박진석,손존광,선홍주,이승,박찬국 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Gastric candidiasis is an uncommon disorder. It is an opportunistic pathogen in immune compromised individuals, alcoholics, persons treated with broad-spectrum antibiotics, immunosuppressive and chemotherapeutic agents. Besides, the use of drugs that reduce the gastric acid production may be a cause of gastric candidiasis. We experienced a case of gastric candidiasis following advanced gastric adenocarcinoma. A 85-year-old woman was admitted to our hospital because of epigastric soreness. Endoscopic findings revealed a large ulcero-infiltrating mass with yellow exudate at cardia of the stomach, which suggested an advanced gastric cancer. Endoscopic biopsy revealed spores and pseudohyphae infiltrating through the ulcerated stomach wall, diffuse infiltration of tumor cells and abortive tumor glands. After treatment with fluconazole 100 mg daily for 21 days, no evidence of the gastric candidiasis was seen on endoscopic biopsy and pathologic findings. The case is herein reported of gastric candidiasis following advanced gastric adenocarcinoma along with a review of corresponding literature.

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