Surgical technique for single-port laparoscopy in huge ovarian tumors: SW Kim`s technique and comparison to laparotomy

( Jeong Sook Kim ),( In Ok Lee ),( Kyung Jin Eoh ),( Young Shin Chung ),( Inha Lee ),( Jung-yun Lee ),( Eun Ji Nam ),( Sunghoon Kim ),( Young Tae Kim ),( Sang Wun Kim ) 대한산부인과학회 2017 Obstetrics & Gynecology Science Vol.60 No.2

Objective This study aimed to introduce a method to remove huge ovarian tumors (≥15 cm) intact with single-port laparoscopic surgery (SPLS) using SW Kim`s technique and to compare the surgical outcomes with those of laparotomy. Methods Medical records were retrospectively reviewed for patients who underwent either SPLS (n=21) with SW Kim`s technique using a specially designed 30×30-cm2-sized 3XL LapBag or laparotomy (n=22) for a huge ovarian tumor from December 2008 to May 2016. Perioperative surgical outcomes were compared. Results In 19/21 (90.5%) patients, SPLS was successfully performed without any tumor spillage or conversion to multi-port laparoscopy or laparotomy. There was no significant difference in patient characteristics, including tumor diameter and total operation time, between both groups. The postoperative hospital stay was significantly shorter for the SPLS group than for the laparotomy group (median, 2 [1 to 5] vs. 4 [3 to 17] days; P<0.001). The number of postoperative general diet build-up days was also significantly shorter for the SPLS group (median, 1 [1 to 4] vs. 3 [2 to 16] days; P<0.001). Immediate post-operative pain score was lower in the SPLS group (median, 2.0 [0 to 8] vs. 4.0 [0 to 8]; P=0.045). Patient-controlled anesthesia was used less in the SPLS group (61.9% vs. 100%). Conclusion SPLS was successful in removing most large ovarian tumors without rupture and showed quicker recovery and less immediate post-operative pain in comparison to laparotomy. SPLS using SW Kim`s technique could be a feasible solution to removing huge ovarian tumors.

민성휘(閔聖徽) 가문의 장서 연구 -7대손 민경속(閔景涑)과 유만주(兪晩柱)의 서적 왕래를 겸하여-

김영진 ( Kim Young-jin ),안정은 ( Ahn Jeong-eun ) 한국한문학회 2020 韓國漢文學硏究 Vol.0 No.80

본고는 조선시대 서책문화, 그 가운데 ‘私家藏書’에 대한 사례 연구를 여흥민씨 閔聖徽(1582~1648) 가문을 대상으로 한 것이다. 연구의 주안점은 두 가지인데 첫째는 민성휘 개인이 본격적으로 형성한 ‘사가장서’의 실체와 특징이고, 둘째는 민성휘의 7대손 閔景涑(1751~1794)의 장서다. 후자의 경우엔 벗 兪晩柱(1755~1788)와의 사이에 이루어진 書冊 相互 借覽과 문학, 학술 담론을 중심에 두었다. 민성휘의 1628년 明 使行에서의 서책 구입과 민경속과 유만주의 교유는 기존 연구성과가 있다. 본고는 기존 성과 위에 민성휘 윗대 아랫대의 저술 및 장서 현황, 소론 당파보인 『簪譜』 및 민경속의 인척 鄭堉이 편찬한 印譜 『圖書譜』, 任天常의 『試筆』 등의 신자료를 추가하여 이 가문의 장서 형성 과정과 그 학술 문화사적 특성을 보다 구체화하였다. 우선 민성휘의 『肅敏書目』을 재검토하고 현존하는 민성휘 장서인이 압인된 책들을 조사하여 관련 방증을 하였다. 또한 민성휘가 수집한 장서와 서책에 대한 관심이 가까이는 민성휘의 『松京訪碑錄』, 閔晉亮의 『唐詩類選』, 閔周冕의 『(新纂)東京誌』로 이어졌고, 멀리는 7세손 민경속의 『知先錄』과 『迂叟謾錄』 및 『輸廫故人錄』, 8세손 閔魯行의 『名數咫聞』과 『咫聞別集』 등으로 이어졌음을 논하였다. 민경속과 유만주 사이에 1785년부터 1787년까지 3년간 지속된 서책 교류를 총정리하였다. 이 둘의 진지하고 진솔한 학술교류는 방문 외에 양가 장서 및 서화의 상호 대차와 감상을 기본으로 하였는 바 두 가문의 당파와 교유권의 차이로 인해 수장 자료의 성격차이 역시 컸다. 이 점이 상대방의 호기심을 일으키고, 부족한 면을 충족시켜 주면서 서로의 성장에 밑거름이 되었다. 민경속의 인척으로 특히 주목되는 것이 ‘江華學’으로 널리 알려진 전주이씨 덕천군파와 연일정씨 鄭夏彦 후손가다. 연일정씨는 또 자하 신위와 연결되어 이후 민노행이 추사 김정희와 교류를 갖게되는 계기가 되었다. 민성휘가의 『서책목록』이 발견되지 않았고, 이 가문의 장서도 다 흩어졌다는 제약과 한계 속에서도 여러 자료의 편린들을 찾아내어 민씨가의 학술문화사적 의의를 추출하여 보았다. 이 과정에서 兪晩柱의 『欽英』이 갖는 서적문화사에서의 높은 의의를 재삼 확인할 수 있었다. 여흥민씨가의 장서와 그것의 학술문화사적 효용은 ‘조선시대 사가장서’의 한 실상과 의미 부여를 하였다는 데에 의의가 있다 하겠다. This thesis focused on the book culture in the Choseon Dinasty period, particularly with the emphasis laid on the family of the Yeoheung Mins by way of the case study on the collection of books at the private family of Seong-Hui Min(1582~1648) of the Yeoheung Mins. The main emphasis is two and the first is the substance and characteristics of ‘the collection of books at private family’ purposefully formulated by the individual Seong-Hui Min and the other is the collection of books of the 7^th descendant Gyeong-Sok Min(1751~1794). In the latter case, the focus was laid on the mutual borrowing and reading of the books and academic discourse with his friend Man-Ju Yoo(1755~1788). The purchase of books by Seong- Hui Min in his envoy trip to Ming in 1627 and the exchange between Gyeong-Sok Min and Man-Ju Yoo were greatly facilitated by Ha-Ra Kim. On top of the achievements of Ha-Ra Kim, this thesis carried out a more realistic review of the background of the formulation of the collection of books at this family and the academic and cultural historical characteristics with reference to the significant new data such as the writings and the status of book collections, the newsletter of Soron Party 『Jambo』, the book of impressions of seals 『Doseobo』 published by Yook Jeong who was a member of Yeonil Jeongs which was a relative family of Gyeong-Sok Min and others. First, this thesis aimed to establish the circumstantial evidence by conducting a review of 『Sukminseomok』 written by Seong-Hui Min and investigating the books belonging to the extant collection of books of Seong-Hui Min. It was verified that most of the pressing books from the extant collection of Seong-Hui Min are wood-block print books from Ming and discussed that the books were scattered from early stages. In addition, it was discussed that the attention to the collections and books established by Seong-Hui Min extended closely to 『Songgyeongbangbirok』 by Seong- Hui Min, 『Dangsiyuseon』 by Jin-Yang Min and 『(New Publication) Donggyeongji』 and remotely to 『Jiseonrok』, 『Osumyeonrok』 and 『Suyogoinrok』 by the 7^th descendant Grong-Sok Min and 『Myeongsuchimun』 and 『Jimoonbyeoljib』 by the 8th descendant No-Haeng Min. The thesis made an aggregate summary of the exchange of books between Gyeong-Sok Min and Man-Ju Yoo which lasted for 3 years from 1785 to 1787. The earnest and sincere academic exchange between them revealed the differences in the books and paintings stored due to the differences in faction, relatives and others apart from the collection of books in each family and these differences made great contribution to their mutual growth by invoking the intellectual curiosity and supplementing the deficient parts of each. The books of Gyeong-Sok Min can be divided between those inherited and those collected by oneself and in regard of the latter it was confirmed that the relative share of the books from Choseon Dynasty was much increased and that the relative families the Jeonju Lees (Deokcheongun family branch - Ganghwahak) and the Yeonil Jeongs inflicted a great influence on the procurement of books. By way of the connection with Jaha Wui Shin, the Yeonil Jeongs offered the opportunity for No-Haeng Min to have exchanges with Chusa Jeong-Hee Kim. Even under the limitation and restriction that 『List of Books』 of the family of Seong-Hui Min was not discovered and the collection of books of the family was all scattered around, the academic and cultural historical implications of the books of the Mins was extracted by discovering the partial fractions of a diversity of data. In this process, the high cultural historical value of the literatures retained by 『Heumyeong』 by Man-Ju Yoo could be ascertained anew. This thesis has the meaning that it highlighted the fact that the collection of books at the Yeoheung Mins and their academic and cultural historical utility reveal a realistic aspect of the ‘collection of books at private families in Choseon Dynasty Period’ and also that it gave such a meaning.

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

Kidney Toxicity Induced by 13 Weeks Exposure to the Fruiting Body of Paecilomyces sinclairii in Rats

Jeong, Mi-Hye,Kim, Young-Won,Min, Jeong-Ran,Kwon, Min,Han, Beom-Suk,Kim, Jeong-Gyu,Jeong, Sang-Hee Korean Society of ToxicologyKorea Environmental Mu 2012 Toxicological Research Vol.28 No.3

Paecilomyces sinclairiis (PS) is known as a functional food or human health supplement. However concerns have been raised about its kidney toxicity. This study was performed to investigate the kidney toxicity of PS by 13 week-oral administration to rats. Blood urea nitrogen (BUN), serum creatinine, and kidney damage biomarkers including beta-2-microglobulin (${\beta}2m$), glutathione S-transferase alpha (GST-${\alpha}$), kidney injury molecule 1 (KIM-1), tissue inhibitor of matrix metalloproteinase 1 (TIMP-1), vascular endothelial growth factor (VEGF), calbindin, clusterin, cystatin C, neutrophil gelatinase-associated lipocalin (NGAL) and osteopontin were measured during or after the treatment of PS. BUN, creatinine and kidney damage biomarkers in serum were not changed by PS. However, kidney cell karyomegaly and tubular hypertrophy were observed dose-dependently with higher severity in males. KIM-1, TIMP-1 and osteopontin in kidney and urine were increased dose dependently in male or at the highest dose in female rats. Increased urinary osteopontin by PS was not recovered at 2 weeks of post-exposure in both genders. Cystatin C in kidney was decreased at all treatment groups but inversely increased in urine. The changes in kidney damage biomarkers were more remarkable in male than female rats. These data indicate that the PS may provoke renal cell damage and glomerular filtration dysfunction in rats with histopathological lesions and change of kidney damage biomarkers in kidney or urine. Kidney and urinary KIM-1 and cystatin C were the most marked indicators, while kidney weight, BUN and creatinine and kidney damage biomarkers in serum were not influenced.

The Proposal of a Verbal Interaction Framework for Elementary Science Teachers

Kim,Jong-young(Jong-young Kim),Shin,Myeong-kyeong(Myeong-kyeong Shin),Kim,Eun-jeong(Eun-jeong Kim) 경인교육대학교 교육연구원 2022 교육논총 Vol.42 No.-

This study is purposed to specifically present and suggest two of the five aspects of the existing framework using data recorded by science class teachers. Mortimer and Scott (2003) viewed teaching purposes, content, communicative approach, patterns of discourse, and teacher intervention as five aspects of classroom discourse analysis, analyzed for secondary science classes. In this study, four episodes were extracted from elementary science classes, the entire analysis was conducted, and the analysis frame developed in this study was applied. The results of the study showed that elementary science classes were analyzed differently according to class flow and the score of the Reformed Teaching Observation Protocol (RTOP). In addition, the analysis framework presented in this study and the score of the RTOP were slightly consistent.

각종 난치성 혈액 질환에서의 비혈연간 골수이식

김동욱,한훈,김정아,김희제,민창기,엄현석,최정현,이종욱,한치화,홍영선,최일봉,신완식,민우성,김학기,김춘추,김원일,김동집 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1

목적: 비혈연간 골수이식은 혈연내에 적절한 골수공여자가 없는 만성골수성백혈병, 고위험군의 급성별혁병, 면역억제치료에 실패한 재생불량성빈혈 및 각종 난치성 조혈모세포질환의 완치를 위한 표준적인 치료방법으로 정착되고 있다. 혈연간 표준적인 동종 이식에 비하여 비혈연간 이식시에는 생착부전, 이식편대숙주반응과 감염이 더 빈번하게 발생하며, 국내에서는 아직까지 체계적인 임상연구결과가 보고된 바 없었다. 이에 본 센터에서는 1995년 10월 이후로 약 20개월간 26예의 비혈연간 골수이식을 시행하였으며 3개월 이상의 추적관찰이 가능하여 이식초기 합병증의 관찰 및 분석이 가능하였던 20예의 환자를 대상으로 이식성적 및 문제점을 보고함으로써 새롭게 확대되고 있는 이 분야의 임상연구 및 진료의 활성화를 꾀하고자 한다. 방법: 각종 혈액 종양질환으로 비혈연간 이식을 시행한 총 26예의 환자중 3개월이상의 추적관찰이 가능하였던 20예를 대상으로 후향적으로 임상경과를 분석한 후 생존 분석을 시행하였고, 환자의 연령, 성별, 질병의 상태, 조식 적합 항원의 일치정도, 이식편대 숙주 반응의 유무와 생존기간과의 상관관계를 살펴보았다. 또한 표준위험군과 고위험군으로 나누어 생존율을 비교하였고 이식과 관계된 생착 부전, 이식편대숙주반응, 감염의 발생과 양상 그리고 그 합병증을 관찰하였다. 결과: 1. 환자와 공여자간에 HLA 불일치가 20예 중 4예에서 있었으며, 생착여부의 확인이 가능했던 17예 중 16예에서 생착이 확인되어 94.1%의 생착율을 보였다. 2. 급성이식편대숙주반응은 62.5%(10/16예)에서 발생하였으며 111도 이상의 급성의 이식편대숙주 반응은 25%(4/16예)에서 발생하였다. 만성이식편대숙주반응은 40%(2/5예)의 환자에서 발생하였으며 이들 모두 국소형으로 중증의 진행형 만성이식편대숙주반응이 관찰된 환자는 없었다. 3. 호흡기 합병증은 10예(50%)에서 발생하였으며 감염성 폐렴을 포함한 호흡기 합병증이 가장 흔한 일차적인 사망 원인이었다. 호흡기 합병증이 발생했던 10예중 6예가 감염에 의한 폐렴이 의심되었고 나머지 4예는 특발성 간질성 폐렴이었다. 4. 8.5개월의 중앙추적기간 중 35%의 생존율을 관찰할 수 있었고, 생존기간은0.5개월에서 15개월 (중앙치:4개월)이었다. 한편 고위험군은 25%(3/12예), 표준위험군은 50%(4/8)의 생존율을 관찰할 수 있었다. 5. 가장 흔한 사망 원인은 감염성 폐렴을 포함한 호흡기 합병증(6예)이었고, 이외의 사망 원인으로는 급성 이식편대숙주반응과 다장기부전이 각각 2예, 생착 부전, 간정맥 폐쇄, 그리고 재발이 각각 1예였다. Unrelated bone marrow transplantation(UBMT) has been increasingly recognized as the standard treatment for cure of chronic myelogenous leukemia, high risk acute leukemia, aplastic failed on immunotherapy, and the variety of refractory hematologic diseases in patients lacking a related donor. However, as compared to HLA identical sibing transplantation, UBMT carries higher incidence of graft failure, graft versus host disease(GVHD), and infection. In our center, 26 patients underwent UMBT between October 1995 and June 1997. The minimum follow-up of 3 months was possible in 20 patients, for whom early complications and clinical outcomes were assessed. The median age of the 20 patients was 24 years. 8 patients had standard risk disease and 12 patients had high risk disease. All patients received various preparative regimens including total body irradiation according to disease and disease status. 19 patients received CsA + short course MTX for GVHD prophylaxis. One patient received marrow that was depleted of T cells ex vivo using avidinbiotin column. The class I loci were typed by serological methods and HLA-A, HLA-B and HLA-DRB1. 3 additional pairs were one minor mismatched at the HLA-B locus. Another one patients was one major mismatched at the DRBI alleles. 17 patients were evaluable for engraftment. Successful enfraftment was confirmed in 16 patients(94.1%). Only one patient who was performed one major DRBI mismatched transplants experienced graft rejection. 16 patients were evaluable for acute GVHD. The overall incidence of acute GVHD developed in 4 patients(25%). Five patients were evaluable for the development of Ⅳ acute GVHD developed in 4 patients (25%). Five patients were evaluanle for the development of chronic GVHD. 2 patients(40%) developed limited chronic GVHD. Respiratory complications including pulmonary infection developed in 10 patients(50%) and these complications were the most common primary cause of death. Of these 10patients, 6 had pneumonia due to fungus(4 patients), pacterial (1 patient), and CMV infection (1 patient) and 4(20%) had idiopathic interstitial pneumonitis and/or adult respiratory distress syndrome. The duration of median follow- up was 8.5 months and 7 of 20 patients(35%) are alive at the time of this analysis with survival duration of 0.5 to 15 months(median survival duration: 4 months). The overall survival was 25% (3/12 patients) in high risk group and 50%(4/8 patients) in standard group. From these results, we can predict that the incidence and severity of GVHD in Korea are lesser than multiracial countries and the long-term survival of patients with standard risk disease can approach that of HLA matched sibling transplants. For the past two years, the performance of UBMT has been rapidly increasing and it will be possible to analyze much larger number of patients soon in Korea. In the future the problems of graft failure, GVHD, and infection due to long lasting immunocompromised status will need to be overcome by continued medical research. In addition, the volunteer donor pool will have to be expanded by the promotion of the national awareness of its need.

장기간 항갑상선제 투여 후 임의 중단 뒤 재복용시 발생한 무과립구증 1 예

김승만;김태영;박수영;배영환;서영경 정은주;김태균;권민정;박정현;이순희 인제대학교 2011 仁濟醫學 Vol.32 No.-

Agranulocytosis, one of the major side effects of antithyroid a gents, probably occurs in less than 0.25% of cases treated with antithyroid agents. It usually occurs within the first several weeks or months after the initiation of therapy, when drug dosage is higher. Most reported cases of agranulocytosis have occurred during the first 3 months of therapy. We describe here a rare case that did not experience the side effect for 6 years of antithyroid agent treatment but presented with agranulocytosis in one month after re-exposure. It suggests that the major side effect such as agranulocytosis can occur in patients who had undergone prior uneventful antithyroid drug therapy.

고대산 북서사면(경기도 연천군) 지역의 식물상 및 산림군락 분류에 관한 연구

김남영,김흥식,김영설,김정유,박완근 江原大學校 森林科學硏究所 2004 Journal of Forest Science Vol.20 No.-

2003년 3월부터 10월까지 고대산을 대상으로 식물상과 산림군락을 조사하였다. 관속식물은 94과 299속 481종 1아종 66변종 4품종 1교잡종으로 총 553종류인 것으로 나타났으며, 한국특산식물은 8과 11속 13종 총 13종류, 희귀 및 멸종위기식물은 12과 15속 15속 15종 총 15종류, 귀화식물은 9과 15속 17종 총 17종류로 나타났다. 산림군락은 신갈나무-철쭉군목, 신갈나무-생강나무군단, 갈참나무-신갈나무군락, 굴참나무-신갈나무군락, 당단풍-신갈나무군락으로 전체 1군목, 1군단, 3군락이 분포하는 것으로 나타났다. The study was carried out to investigate the flora and community classification of forest vegetation in Mt. Godae from March to October, 2003. As a result of that, the vascular plants were 94 families, 299 genera, 481 species, 1 subspecies, 66 varieties, 4 formae, 1 hybrid, 553 taxa in all; korean endemic plants were 8 families, 11 genera, 13 species, 13 taxa in all; rare or endangered plants were 12 families, 15 genera, 15 species, 15 taxa in all; naturalized plants were 9 families, 15 genera, 17 species, 17 taxa in all. forest vegetation was classified into 1 order, 1 alliance, 3 communities; Rhododendro - Quercetalia mongolicae (Kim 1990) Lindero - Quercion mongolicae (Kim 1990) A. Fraxinus rhynchophylla - Quercus mongolica Community B. Quercus variabilis - Quercus mongolica Community C. Acer pseudo-sieboldianum - Quercus mongolica Community