네모나프라이드의 유효성 및 추체외로 부작용 : Haloperidol 및 Risperidone과의 자연관찰적 개방형 비교연구 A Naturalistic Open Comparative Study with Haloperidol and Risperidone

서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psycho­pathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.

아동 정신건강서비스에 대한 요구도 및 실제 이용에 관한 예비적 연구

김신영,조선미,임기영,정영기,신윤미 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : We aimed to identily the degree of perceived need and use of child mental health services, and to examine the factors associated with the perceived need and use of the child mental health services. Methods : The sample consisted of 3,477 children aged 8 to 13 years. The parents completed the sociodemographic data, the Korean version of the Child Behavior Checklist (K-CBCL), and the Korean version of DuPaul's Attention Deficit Hyperacti-vity Disorder Rating Scale (K-ARS). Results : Overall, 10% of children demonstrated the need for mental health services, and 2.36% utilized the child mental health services. All subcategoiy scores of K-CBCL and K-ARS were significantly low in the no help needed group. Factor sassociated with the actual use ofchild mental health services included social problems and thought problems. Conclusion : The demand for child mental health services is high, but only a small number of children are using mental health services. To increase actual use, it is necessary to educate and campaign for various child mental health.

낮은 상관 특성과 큰 선형 복잡도를 갖는 새로운 p-진 수열군

김영식(Young-Sik Kim),정정수(Jung-Soo Chung),노종선(Jong-Seon No),신동준(Dong-Joon Shin) 한국통신학회 2008 韓國通信學會論文誌 Vol.33 No.7C

최근에 홀수인 소수 p, n=4k, 그리고 d=((p<SUP>2k</SUP>+1)/2²에 대해서 Seo, Kim, No, Shin<SUP>[1]</SUP>이 m-sequence와 d로 decimation한 부분 수열들 사이의 상관 분포를 유도하였다. 하지만 이러한 상관 분포로부터 수열군이 자명하게 결정되지는 않는다. 본 논문에서는 우선 위의 상관 특성을 유지하는 수열군을 선택하는 방법을 제시한다. 더 나아가서 이 수열군과 동일한 상관 특성을 가지면서도 더 큰 선형 복잡도를 갖는 수열군을 새롭게 생성할 것이다. 끝으로 3진 수열의 선형 복잡도를 특정 경우에 대해서 유도하고 이 경우 원래의 수열군보다 더 큰 선형 복잡도를 가짐을 보일 것이다. For an odd prime p, n=4k, and d=((p<SUP>2k</SUP>+1)/2², Seo, Kim, No, and Shin<SUP>[1]</SUP> derived the correlation distribution of p-ary m-sequence of period pⁿ-1 and its decimated sequences by d. In this paper, two new families of p-ary sequences with family size p<SUP>2k</SUP> and maximum correlation magnitude 2√pⁿ-1 are constructed. The linear complexity of new p-ary sequences in the families are derived in the some cases and the upper and lower bounds of their linear complexity for general cases are presented.

벌 자상에 의해 발생한 횡문근융해증과 급성신부전

박상곤,김영대,강지은,신정현,신병철,박차영,정춘해 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2

Rhabdomyolysis is a syndrome characterized by muscle necrosis and release of intracellular muscle constituents into the circulation. The spectrum of causes is quite broad and included disorders of traumatic, metabolic, infectious and toxic origin. However, rhabdomvolvsis and acute renal failure following bee sting is rare and its pathogenesis is not well known. We experienced a case of 63-year-old man with acute renal failure and rhabdomyolysis caused by bee sting. He was stung by bee on scalp and neck. Oliguria was developed within several hours. He has fully recovered after general supportive care including fluid therapy and diuretics. This case demonstrates that rhabdomvolysis with consequent acute renal failure are able to developed by bee sting.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.

남자 중학생의 식품 중량과 열량을 중심으로 한 영양교육 효과에 관한 연구

신혜주,김은영,배윤정,승정자 숙명여자대학교 건강·생활과학연구소 2006 生活科學硏究誌 Vol.- No.22

This study was planned to suggest countermeasure of nutrition education by investigating adolescents, dietary behavior, food weight, and acknowledgement of food calories. 210 middle school boys were selected and asked to fill out the questionnaire. The subjects were divided by nutrition education experience; 1st grade who received nutrition session and 3rd grade who divided subjects. In terms of acknowledgement of food calories subjects nutrition education experience had more recognition for calories than the other group(p<0.01). When one bowl of rice, a potato, a bowel of kimchi and a carrot were asked. However recognition for meats, fishes and eggs were not different between two groups. Among milk and dairy foods the educated group showed high recognition both calories and weight of a piece of cheese than the other(p<0.05). The educated group showed better recognition for calories and weight of tea-spoon of butter, a tea spoon of oil and a tea-spoon of mayonaise, compared to the other group(p<0.01, p<0.05, p<0.05). Also the educated group showed better recognition for calories and weight of a packet of shrimp snack than the other group. The results of this study suggest that nutrition education improved the recognition of calories and weights of foods in study subjects. Also, the number of foods recognized for their calories and weights was higher among subjects who received nutrition education. These results will influence the choice the food by adolescents. Also the nutrition education are thought to be more effective by using photographs or food models, not just by lectures on theories.

비디오시스템과의 일체형 지면반력 Windows 프로그램 개발

신인식,문영진,정철수,이기청 서울대학교 체육연구소 2000 서울大學校 體育硏究所論集 Vol.21 No.2

The study was designed to develop the window version force platform from the former program operated in DOS version. The window version program was developed utilizing a visual-basic program of Microsoft Inc. The characteristics of the program are as follows: 1.The compatibility among the board was enhanced so that all AD board of Data Translation Inc. can be utilized. 2.The program can be operated with the connection to the image analysis system which consists of force platform and D-5100 Panasonic Video Camera. 3.The automation of analysis was achieved so that the variable can be analyzed immediately after the button on the force platform was pressed. 4.Multi-file processing was adopted so that several files can be performed simultaneously for the analysis. 5.The program was designed in user-friendly mode. The program can be operated by even novice because the main menu was composed in flowchart format. There were not significant differences between the values obtained utilizing the program developed in the present study and the former program. The present results suggest that the program developed in this study may have advantage with regard to conveniency and economical efficiency over the expensive programs imported from the foreign countries.

NaCl이 보리(Hordeum vulgare L.) 잎의 엽록소 형광에 미치는 영향

정화숙,임영진,박강은,박신영 한국환경과학회 2004 한국환경과학회지 Vol.13 No.12

This study was conducted to investigate the changes of chlorophyll contents and chlorophyll fluorescence in barley(Hordeum vulgare L.) 7 day old seedling treated with 0.2M, 0.4M, 0.6M, 0.8M, and 1.0M NaCl concentration containing Hepes buffer(pH 7.5). Barley was affected by NaCl treatment. The chlorophyll a, b and carotenoid of barley decreased with an increase in NaCl concentration. However, chlorophyll a, b and carotenoid of barley were not greatly influenced by o.8M and 1.0M NaCl. Fv, Fv/Fm and qP were gradually decreased by higher concentration of NaCl. qP, qNP, qR and qE were gradually decreased by 6hr. During barley chloroplast was development NaCl affected chlorophyll synthesis than photosynthetic activity. Whereas barley seedling leaves were more influenced photosynthetic activity than chlorophyll contents by NaCl.

응급실을 내원한 구강악안면외과 안면골 골절 환자의 변화에 대한 비교 연구

신상훈,성화식,강영훈,황대석,김용덕,김욱규,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.24

Although there have been many clinical studies about the facial trauma in the recent as well as in the past, severity and frequency of facial trauma are reported multifarious. It seemed to be because of variety of social, cultural, and environmental factors, and the view point of investigators. In this study, we investigated about the patients visiting emergency room during recent 4 years(2004-2007), and compared with retrospective study during former 10 years(1992-1996, 1999-2003) in Dept. OMS Pusan National University Hospital. We assessed the cause, type, demographic, etc, and analyzed alterations of facial bone fractures during past 3 periods. The results were as follows. The total number of patients was increased. 429 patients treated for maxillofacial fractures between January 1992 and December 1996, 466 patients treated between January 1992 and December 1996 and 764 patients treated between January 2004 and December 2007. The male-to-female ratio were 4.6:1, 3.9:1, and 4.16:1, respectively. Patient in the age groups of 10-19 years and 20-29 years increased in the latter two periods. Assaults and falls are decreased gradually, but slip down s are increased. Traffic accidents are still major cause of facial trauma. The mandibular fractures showed the highest incidence thorought three periods. Symphysis fractures of mandible was increased and condyle fractures of mandible was drecreased in the third period.