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RISS 인기검색어
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- 저자 : 김계훈 (검색결과 556 건)
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김계훈,윌리암밀러 한국농화학회 1995 Applied Biological Chemistry (Appl Biol Chem) Vol.38 No.2
Single-drop splash/detachment studies and multiple-drop splash/detachment experiments were carried out to measure detachment by single and multiple drops. A raindrop tower 7.0 m in height was used to study soil splash by single drop raindrop impact over time on repacked soil samples in containers 76.2 ㎜ in diameter. The waterdrop diameter and kinetic energy were ≤1 ㎜ and 1.22×10^(-3) J drop^(-1), respectively. The samples consisted of five agricultural topsoils sieved to $lt;2 ㎜, varying from sandy loam to clay loam in texture. The average weight of splashed soil particles after 75 drops did not show any significant difference between the five soils. The average weight of particles splashed by the first 15 drops showed that the sandy Pelham soil splashed to a greater degree than the others, and was therefore more detachable (p=0.05) than the other soils. The average weight of particles splashed by the last 15 drops also showed that the Pelham soil was the most detachable, with Cecil, Appling, Dyke, and Worsham soils being progressively less detachable. The effect of multiple drops on detachment was studied under a nozzle-type rainfall simulator at 74.9 ㎜ h^(-1) intensity for 85 min using the same soils as the single drop experiments. The total soil splash value for 85 min on Appling, Cecil, Dyke, Pelham, and Worsham soils were 6121, 6206, 4183, 5160, and 3247 g m^(-2), respectively. There were no obvious relationships between soil loss measured from the different experiments.
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김계훈,이우석,조정선,윤현주,안영근,정명호,조정관,박종춘,강정채 한국심초음파학회 2008 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.16 No.1
Precutaneous transcatheter device closure of interatrial communications is used as an alternative to surgery or long-term anticoagulation for the treatment of patients with paradoxical cerebral embolism. We report a case of successful percutaneous transcatheter closure of small atrial septal defect in a 34 year old female patient with acute cerebral infarction presumably caused by paradoxical embolism through the defect. Precutaneous transcatheter device closure of interatrial communications is used as an alternative to surgery or long-term anticoagulation for the treatment of patients with paradoxical cerebral embolism. We report a case of successful percutaneous transcatheter closure of small atrial septal defect in a 34 year old female patient with acute cerebral infarction presumably caused by paradoxical embolism through the defect.
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고혈압 환자에서 동맥경직도와 좌심실 이완기 기능 및 운동 수행능에 대한 안지오텐신 전환효소억제제의 효과
김계훈,박종춘,오춘순,최승희,김미란,이우석,윤현주,안영근,정명호,조정관,강정채 대한노인병학회 2009 Annals of geriatric medicine and research Vol.13 No.1
Background: The aim of this study was to investigate the relations between arterial stiffness, diastolic function, and exercise performance and the effects of angiotensin-converting enzyme inhibitor (ACEI), perindopril, in these three areas in patients with hypertension (HT). Methods: A total of 39 patients (60.9±4.9 years, 23 males) with a newly diagnosed or untreated HT, stage I, were enrolled. Arterial stiffness measured by pulse wave velocity, diastolic function measured by echocardiography, and exercise performance and hemodynamic parameters measured by a treadmill exercise test were compared before and after 6 months of medical treatment with an ACEI. Results: The parameters for arterial stiffness, diastolic function, and exercise performance did not show significant correlations with each other at baseline. Systolic (from 147.6±6.5 mm Hg to 134.3±9.6 mm Hg, p<0.001) and diastolic blood pressures (from 87.7±7.5 mm Hg to 82.9±6.2 mm Hg, p<0.001) decreased significantly after 6 m onths of ACEI treatment. Except for duration of total exercise time, the parameters for arterial stiffness, diastolic function, and th hemodynamic response to exercise also improved significantly after 6 months of ACEI treatment. Conclusion: Though the parameters for arterial stiffness, diastolic function, and exercise performance were not associate with each other at baseline, they all improved significantly after 6 months of medical treatment with an ACEI in elderly patients with stage I HT. The results of this study suggest the possibility of additional benefits of ACEI beyond lowering blood pressure. 연구배경: 고혈압 환자에서 동맥경직도와 이완기 심기능 및 운동수행능과 연관된 인자들의 연관성에 대한 연구는 드물다. 따라서 본 연구를 통해 이들 인자들 간의 상호연관성 및 ACEI의 사용이 이들 인자들에 미치는 효과에 대해 알아보고자 하였다. 방법: 전남대학교병원 심장센터와 건강 검진센터에 내원하여 처음으로 고혈압이 진단되었거나, 고혈압이 진단 되었으나 항고혈압제를 복용하지 않았던 55세 이상의 1단계 고혈압 환자 39명(60.9±4.9세, 남자 23명)을 대상으로 하였다. PWV로 측정된 동맥경직도, 심초음파로 측정된 이완기 심기능 및 운동부하 검사로 측정한 운동수행능과 혈역학적 변화들을 ACEI 사용 전과 사용 6개월 후 측정하여 비교하였다. 결과: 연구 시작 시점에서 동맥경직도, 이완기 심기능 및 운동수행능과 연관된 인자들 사이에 유의한 상호 연관성은 없었다. 6개월 간의 ACEI 사용 후 수축기 혈압은 147.6±6.5 mmHg에서 134.3±9.6 mmHg로, 이완기 혈압은 87.7±7.5 mmHg에서 82.9±6.2 mmHg로 유의하게 감소하였다. (p<0.001). 동맥경직도, 이완기 심기능 및 총 운동 시간을 제외한 운동 수행능과 연관된 인자들도 6개월 간의 ACEI 사용 후 유의한 호전을 보였다. 결론: 고혈압을 갖는 환자에서 동맥경직도, 이완기 심기능 및 운동수행능과 연관된 인자들은 서로 유의한 연관성은 없었으나, 6개월 간의 ACEI 사용으로 유의하게 호전 되었다. 본 연구의 결과는 ACEI가 혈압강하 효과 외에 고혈압 치료에 있어서 다른 이로운 효과가 있을 가능성을 시사하였으나, 이의 입증을 위해서는 혈압 강하 효과가 비슷한 다른 대조군과의 비교 연구가 필요할 것으로 생각된다.
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