서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

고관절 운동 방법에 따른 20대 성인의 허리 유연성 비교

한진태,유재응 대구대학교 특수교육재활과학연구소 2007 再活科學硏究 Vol.25 No.2

The purpose of this study is to know what is the efficient exercise and to determine the most efficient exercise in lumbar flexibility. Therefore, in this experiment, three hip joint flexion exercises were carried out in order to see which improves the most in lumbar flexibility. The test was carried out with E university students divided in three groups, Group A: hip flexion and knee extension with supine, Group B: hip flexion and knee flexion with supine and Group C: hip flexion and knee extension with sitting- each group consisted of 13 people and everyone participated in doing the warming-up exercise, main exercise and cool-down exercise which lasted about 20 minutes and this program was done 5 times a week during the period of 6 weeks. To find out the results, we did the sit and reach test using T.K.K.4308B of Japan. We measured the results once a week and in total 8 times including initial and last measurement. The result of this study showed that each exercise method applied in each group contributed in improving lumbar flexibility. The following results show the improvement in lumbar flexibility. According to this study, Group C(T=-14.305, P=.000) had the highest degree of flexibility improvement followed by Group A(T=-10.343, P=.000) and then Group B(T=-12.012,P=.000). This study showed that the hip joint flexion exercise of these three groups have a positive effect on lumbar flexibility improvement. Furthermore, it has been proved from the study that the best among the three methods in increasing the lumbar flexibility is the exercise done by Group C.The purpose of this study is to verify the difference of effect between group and period in order to find out effect on lumbar flexibility of treatment modality(stretching, heat - stretching) and period. The subject was chosen from the mild physically normal person who range from 20 to 40 years old without any neurological problem. 본 연구는 대학생들을 대상으로 유연성 향상을 위한 여러 가지 방법 중 임상에서 주로 사용되어지는 고관절 굴곡 운동 방법을 3가지로 나누어 6주간 실시한 후 앉아 윗몸 앞으로 굽히기(Sit-and-Reach Test)로 측정 비교하여 어느 운동이 허리 유연성에 더 많은 영향을 주는지를 알아보고, 그 효과의 차이를 살펴보는데 목적이 있다. 총 39명의 대학생을 대상으로 13명씩 세 그룹으로 나누어 6주간 실험을 실시하였으며 측정방법으로는 좌 전굴 측정계를 사용하여 운동전과 운동 후의 허리 유연성 변화를 분석한 결과 다음과 같은 결론을 얻었다. 1. 각 그룹에 적용된 각각의 운동 방법 모두 피 실험자들의 유연성 향상에 기여를 한다. 2. 세 그룹의 유연성 향상의 정도가 차이가 있고 유연성 향상 정도는 C그룹, A그룹, B그룹 순으로 향상 되었다. 이상의 결론을 종합해 보면 세 그룹의 고관절 굴곡운동은 허리유연성 향상에 긍정적인 영향을 미쳤으며 그 중 그룹 C의 Hip flexion and knee extension with sitting방법이 허리 유연성을 증가시키는데 가장 큰 효과를 보였다.

수종보익제가 면역세포의 조절 및 Apoptosis에 미치는 영향

한종현,강성용,정현우,오찬호,권진,은재순 대한본초학회 1997 大韓本草學會誌 Vol.12 No.1

The effects of several tonifying prescriptions on the apoptosis of transplanted L1210 cells and the regulation of immune cells in L1210-transplanted mice were studied. Sa-Mul-Tang(SMT), Sa-Kunja-Tang(SKT), Sipjeon-Daebo-Tang(SDT) accelerated the apoptosis of transplanted L1210 cells, and SMT and SKT reduced the mitochondrial transmembrane potential of transplanted L1210 cells. SMT promoted the proliferation of thymocytes and splenocytes in L1210-transplanted mice. Whereas SMT increased CD8+ T_c/T_S cell, Bojung-Ikki-Tang(BIT) decreased CD4+ T_H cell population in the thymocytes of L1210-transplanted mice. SMT and SKT increased the lucigenin chemiluminescence from peritoneal macrophage of L1210-transplanted mice. These results indicate that SMT and SKT have an inductive action of apoptosis of transplanted L1210 cells and peritoneal macrophage activation.

6MV 선형가속기의 비대칭조사야 사용에 대한 변형된 wedge의 선량측정인자의 분석

한재진,지연상 광주보건대학 1999 論文集 Vol.24 No.-

The wedge factor was comparied with wedge angle for symmetric field and asymmteric field. The results are follows; 1. The wedge factor values were increased with smaller wedge angle and larger field size. 2. Variation ratio of wedge factor for asymmetric field was smaller then symmetric field. 3. The variety of wedge factor ratio was large for increasing the field size and wedge angle. 4. The error of symmetric field and asymmetric field was indicated average values of 0.6%.

경피적 전기 신경 자극과 간섭파 치료의 동통 완화 기전에 대한 연구 -날록손 투여가 흰쥐의 꼬리 회피 반사와 뇌 척수액 내 베타 엔돌핀 농도에 미치는 효과-

김진호,한태륜,방문석,김돈규,권범선,임재영 大韓再活醫學會 1997 Annals of Rehabilitation Medicine Vol.21 No.6

만성 신부전 환자에서 혈액투석에 의한 Isoniazid의 제거

신재국,차인준,장인진,신상구,김윤구,한진석,김성권 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.2

백화사설초 메탄올 추출물에 의한 HL-60 細胞 枯死過程에서의 cell cycle 關聯因子의 活性變化 硏究

한세희,이종범,문구,문석재,원진희,박래길,이종덕 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Objecives: Hedyotis diffusa is used to treat cancer in traditional Korea Medicine. So this study was carried out to examine the expression of cell cycle related genes in HL-60 cells undergoing apoptosis by the methanol extract of Hedyotis diffusa. Methods: 1. HL-60 cells were treated with various concentrations (from 200 to 50㎍/ml)of metnanol extract and H20 extract (200 ㎍/ml) of hedyotis diffusa. After 48 h later, the cells were tested for viability by MTT assay. 2. The HL-60 cells were treated with 200 ㎍/ml of methanol extract for the indicated periods. The whole cell lysates were prepared and analyzed by westem blotting using anti-p53 antibody. 3. The nuclear extract were prepared and analyed by western blotting using anti-p21 antibody, anti-p27 antibody, anti-cyclen A antibody, anti-cylin E antibody and anti-CDK2 antinbody. Results: 1. The methanol extract of Hedyotis diffusa induced the death of HL-60 cells in a dose dependent manner. 2. The methanol extract of Hedyotis diffusa makedly decreased the level of p21/Cipl and cyclin A in a time dependent manner. 3. The methanol extract of Hedyotis diffusa markedly increased tje ;eve; pf p27/Kip and cyclin E in a time dependent mammer. 4.The methanol extract of Hedyotis diffusa markedly did not affect the level of CDK2. Conclusions: These results provide evidence that expression of cell cycle related genes in HL-6- cells undergoing apoptosis by the methanol extract of Hedyotis diffusa mainly results from decreased level of p21/cipl and increased level of p27/Kipl of the cell cycle related genes.

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

Destructive Encephalopathy를 보인 Incontinentia Pigmenti 1예

한진규,최재철,박민규,박건우,은백린,정지태,이대희 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5