http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 발행기관 : 대한본초학회 (검색결과 1,977 건)
- 무료
- 기관 내 무료
- 유료
-
-
-
-
-
김경호 ( Kyung Ho Kim ),정현우 ( Hyun Woo Jeong ),이동원 ( Dong Won Lee ),김정숙 ( Jeong Sook Kim ),김영균 ( Young Gyun Kim ),조수인 ( Su In Cho ) 대한본초학회 2003 대한본초학회지 Vol.18 No.1
Objectives : The effects of Radix Polygalae extract were tested for the anti-sociopsychological stress action. Methods : 100g of crude drug of Radix Polygalae was extracted with pure water and the total extractive was evaporated under reduced pressure to give 17.0g. ICR male mice(20±2g) were fed orally with the dose of 100mg/kg/day for five days. Mice were exposed to sociopsychological stress by restraining and seeing foot shock stressed mice for one hour for five days. Results : Radix Polygalae extract administered group showed a significant decrease of serum corticosterone secretion compared with control group. Noradrenaline secretions in the dorsal cortex of brain showed no change. Lipid peroxidation and cytotoxicity of the liver of mice were tested by measuring malondialdehyde and serum level of aspartate amintransferase(ALT), and Radix Polygalae extract admistration decreased serum level of ALT. Serum level of malondialdehyde did not changed either. Conclusion : Above results suggest that Radix Polygalae extract can effectively rid the sociopsychological stress.
-
-
자오가 및 분획물의 성장기 흰쥐 장골 길이 성장에 대한 효과
박선영 ( Sun Young Park ),임강현 ( Kang Hyun Leem ),김호철 ( Ho Cheol Kim ) 대한본초학회 2003 대한본초학회지 Vol.18 No.1
Objectives : Acanthopanacis Senticosi Radix, the dried root of Acanthopanax senticosus (Rurp. et Maxim.) Harms. is one of the widely used drugs in traditional Korean medicine. This study was designed to investigate the effects of A. senticosus and its subfactions on the groowth of longitudinal bone in the adolescent male rats. Methods : A. senticosus extract was lyophilized after 70 % ethanol extraction, and fractionated by hexane, ethyl acetate and water. Water fraction was further fractionated according to the solubility against ethanol. Longitudinal bone growth was measured by fluorescence microscopy after injection of tetracycline, which formed fluorescent band to the bone forming sites. Results : Treatment of A. senticosus extract (100 mg/kg) significantly enhanced longitudinal bone growth (p<0.01) compared with control group. Water fraction increased bone growth significantly, but other two fractions did not. Both subfractions of the water fraction increased bone growth significantly. Conclusion : Administration of A. senticosus extract enhanced longitudinal bone growth of the adolescence male rats, and its active components might be contained in water fraction.
-
김석근 ( Seok Keun Kim ),송호준 ( Ho Joon Song ),박기현 ( Ki Hyun Park ),신민교 ( Min Kyo Shin ) 대한본초학회 2003 대한본초학회지 Vol.18 No.1
Objective : This study was carried out to evaluate effect of expectorant by semen Benincase an its various fraction in the trachea of rats(SP-D, M. 105g). Methods : After a single intraperitoneal injection of water extract, 100, 200, 400mg/kg, b.w, respectively, the contents of histamine, acetycholine and serotonin, which are neurotransmitters, exhibited maximum levels at 120 min as a time course in the rat trachea. However, there were no differences of neurotransmitter contents related with the dose of 200 or 400mg. When rats were administrated with the water extract (200mg/kg, b.w), the protein-bound hexose, a major component of mucin or mucus, was secreated about 118% as compared with the control at 120 min in the rat trachea. The period of treatment was scheduled so as to obtain the maximum activity of lysozyme as an important enzyme for the liquefaction of mucus as indicated in time course study. Results : the results from this approach were in the complete agreement with pattern of hlycoprotein secretion. Microscopic observation after treatment with the water extract or its various fractions (Fr-Ep, A, B) to the tracheal tissue of rats showed that Fr-B possessed a significant effect on the activity of ciliary movement. Administration of the water extract or Fr-B stimulated the secretion of phenol red dye or fluorescein sodium associated with mucus content of tracheobronchial lumen of rats. Especially, the secretion of fluorescein sodium by treating Fr-B had a makedly stimulatory effect (131%) as compared to the control after 120min. Conclusion : On the basis of this study, it was sugested that Semen Benincasae might be very useful for the stimulation of expectorant activity.
-
오수수와 그 분획물이 흰쥐의 흉부대동맥과 복대동맥에 미치는 혈관이완효과
김형환 ( Hyung Hwan Kim ),조남훈 ( Nam Hoon Cho ),김완기 ( Wan Gi Kim ),이상준 ( Sang Jun Lee ),유익동 ( Ik Dong Yu ),안덕균 ( Duk Kyun Ahn ),최호영 ( Ho Young Choi ) 대한본초학회 2003 대한본초학회지 Vol.18 No.1
Objectives : We have examined the relaxational response to the methanol extract of Osusu in isolated thoracic aorta and abdominal aorta from sprague dawley (SD) rat. Methods : Rat thoracic aorta and abdominal aorta were investigated in vessel segments suspended for isometric tension recording by polygraph. To compare the vasodilation effect, put Osusu extract and fractions into them which vessels were precontracted by 5-hydroxytryptamine (5-HT). Results : We found out this result ; the thoracic aorta segments were responded to Osusu with a dose-dependent and concentration-dependent vasorelaxation. The thoracic aorta and abdominal aorta segments were responded to Osusu with a dose-dependent vasodilation. The 5-HT induced vasocontraction at 10^-5M were vasodilated such as 96.8% in thoracic aorta with 30 mg/ml Osusu (Root). Addition of 10 mg/ml Osusu in thoracic aorta which was precontracted by the 5-HT at 10^-5M were come out differently 44.5% (fr. 1; 80% methanol fraction), 56.4% (fr. 2; hexane fraction), 7.2% (fr. 3; chloroform fraction), 16.8% (fr. 4; ethyl acetate fraction), 54.9% (fr. 5; butanol fraction) and 18.3% (fr. 6; water fraction). Osusu (1 mg/ml) in abdominal aorta which was precontracted by the 5-HT at 10^-5M were come out differently 87.1% (fr. 1; 80% methanol fracton), 76.9% (fr. 2; hexane fraction), 47.2% (fr. 3; chloroform fraction), 63.2% (fr. 4; ethyl acetate fraction), 25.2% (fr. 5; butanol fraction) and 34 9% (fr. 6; water fraction). Conclusion : Osusu methanol extract and fractions-induced relaxation in the isolated rat thoracic aorta and abdominal aorta were come out be dose-dependent relaxation.
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
