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한상원,최석구,전영빈,이윤우,유원상 인제대학교 1990 仁濟醫學 Vol.11 No.4
수술전 심전도의 가치를 평가하기 위해 500례의 심전도들을 판독하고 심전도상 이상 소견을 보인 예들을 추적하였다. 176례들(35%)이 이상 소견을 보였으나 심근경색으로 판독된 5례들(1%)에서만 추가 검사를 실시하였고, 그 결과 4례(0.8%)에서 수술이 연기되었다. To evaluate the value of pre-operative electrocardiogram which has been taken nearly as a routine test, 500 pre-operative electrocardiogram were reviewed and consequent measures on the basis of abnormal electrocardiogram were investigated. 1.176 ECG's (35%) showed abnormal findings, but more than half of them were only minor changes. 2.20 cases (4%) wore referred to the cardiology section or the department of anesthesiology. 3.5 cases (1%) underwent further evaluations. such as serial ECG tracings, echocardiography, cardiac scan, measurement of cardiac enzymes. cardiac catheterization or coronary arteriography. 4.All above 5 cases showed findings of myocardial infarction. 5.Operation was deferred in 4 cases (0.8%).
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Early Dorsal Midbrain Syndrome Mimicking an Adie’s Tonic Pupil
한상원,류정호,백종삼,김정연,황용순,박재현 대한신경과학회 2010 Journal of Clinical Neurology Vol.6 No.1
Background While tonic pupils have been attributed to various diseases, including syphilis,herpes zoster, orbital trauma, temporal arteritis, endometriosis, and paraneoplastic syndromes,obstructive hydrocephalus has not been implicated. Case Report A 36-year-old woman visited a neurology department with a 7-day history of throbbing headache and blurred vision in both eyes. She had early dorsal midbrain syndrome mimicking an Adie’s tonic pupil, and cholinergic supersensitivity was demonstrated using topical 0.125% pilocarpine. Brain MRI revealed obstructive hydrocephalus at the level of the aqueduct of Sylvius, and her symptoms resolved 4 days after surgery. Conclusions We report a patient with early dorsal midbrain syndrome that was initially believed to represent a tonic pupil on the basis of pharmacologic testing. The findings in our patient suggested that early dorsal midbrain syndrome mimicking an Adie’s tonic pupil can be caused by obstructive hydrocephalus compressing the Edinger-Westphal nucleus.
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녹용약침액(鹿茸藥鍼液)의 DNA chip을 이용(利用)한 유전자(遺傳子) 발현(發顯) 분석(分析)
한상원,서정철,이윤호,최제용,Han, Sang-won,Seo, Jung-chul,Lee, Yun-ho,Choi, Je-yong 대한침구의학회 2003 대한침구의학회지 Vol.20 No.3
Objective : Bone homeostasis is maintained by balance of bone formation and resorption. Therefore, bone related diseases arose by disturbance of this balance between osteoblast and osteoclast activities. To develop a successful screening system the therapeutic components based on oriental medicine is essential to set up systematic approach for that purpose. The purpose of this study is to the know the gene expression using cDNA microarray assay. Methods : Cervi Pantotricuhum Cornu Herbal-acupuncture extract was prepared by boiling. human osteosarcoma cells(HOS) were treated with Cervi Pantotricuhum Cornu Herbal-acupuncture solution. Then mRNA was extracted and cDNA microarray assay was performed. Results : Human osteosarcoma cells(HOS) treated with Cervi Pantotricuhum Cornu Herbal-acupuncture solution($500{\mu}g/m{\ell}$) showed that thioredoxin, TAFII31 and two novel genes were increased. However many genes decreased their expression by Cervi Pantotricuhum Cornu Herbal-acupuncture. Conclusions : This type of approach will give a good chance to explore the favorable effects of Cervi Pantotricuhum Cornu Herbal-acupuncture. Further study is needed for investigating the effect of Cervi Pantotricuhum Cornu Herbal-acupuncture.
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