글라스 아이오노머와 레진수복물 변연의 우식내성에 관한 비교실험연구

사우경,손일수,김용기 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

Standardized cavities were prepared on 60 permanent teeth which had been selected according to inherent fluoride ion content of enamel and several glass ionomers and composite resins were restored. After classification and deposition for 1, 2 and 3 weeks, artificial caries was made on these specimens and resulting histologic appearances and depths of the lesions were observed by a polarizing microscope. Then caries resistant effects of each materials were compared and analyzed. In groups of Ketac-Fil and Fuji Ⅱ, the depth of lesion was increased markedly as the distance had been far away from the margin of restoration materials, wherease in the control group(Silux Plus), lesion depth was deeper than the experimental group and uniform depth of lesion was made despite of the distance from the margin. Fluoride ion content released in solution was higher in Ketac-Fil, Fuji Ⅱ, Silux Plus by descending order and statistically significant difference between groups could be found.

강구조물 설계규준의 신뢰성평가와 신뢰성설계기준에 관한 연구

정철원,손용우,이증빈 圓光大學校 1996 論文集 Vol.32 No.2

There is need to balance safety, economy and serviceability in all phases of society problem. This sis especially true in structural code formulation, where a framework is established by which practicing structural engineers can be assured of designing structures that reasonably meet the above three objectives. The existing design codes, which are generally based on the structural theory and certain engineering experience, do not realistically consider the uncertainties of loads and resistances and the basic reliability concepts. The purpose of the present study is therefore to develop the realistic reliability-based design criteria to secure adequate safety and reliability. To this end, the reliability levels of our existing design code for steel structures are first evaluated and the target reliability are determined, and new code formats are evolved from these target reliabilities.

1~2기 본태성 고혈압 환자들에서 Imidapril 대 Enalapril의 항고혈압 효과를 평가하기 위한 무작위, 이중맹검 임상시험

최영진,손대원,김용진,이홍자,채인호,김효수,김철호,오병희,이명묵,박영배,채윤식,이영우 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.11

P.S. 콘크리트 보의 비선형 최적설계

정철원,최규문,손용우 圓光大學校 1994 論文集 Vol.28 No.2

비선형 최적설계법을 개발하였다. 이 방법의 목적은 PC구조물의 극한에서 나타나는 거동을 예측하는 것이다. 그에 따른 주요결과를 제시하였고 콘크리트와 강의 실제 거동의 실험 과정에서 겪는 난점을 거론하였다. 특히 PC강선에서 이용가능한 다양한 응력-변형 관계를 비교하고 실제 특성에서 나타난 차이점을 관찰하였다. 그 관계들에 관하여 추천된 식들의 해당계수를 제시하였다. 그 결과는 PC강선의 종류와 양, 비 프리스트레스 인장과 압축철근의 양, 극한 콘크리트압축변형 등과 같은 주요 변수들의 극한 거동에서 영향이 나타난다는 것이다. 그 영향과 결과를 유도한 규준을 비교하는 데에 중점을 두었다. 이 연구에서 얻은 결과들로써 만약 추천된 규준을 사용하는 경우에 그 규준이 불안정한 설계를 유도할 가능성이 있는 부분과 또 관찰된 경향에 알맞게 규준을 수정하기 위하여 필요한 점을 지적할 수 있게 되었다. An approximate nonlinear design procedure is development. It is the aim of the procedure to predict the behavior at ultimate of prestressed and partially prestressed concrete members. We showed the main results and discussed some difficulties which we come (on in) simulating the actual behavior of concrete and steel. Especially the various available stress-strain relationships for prestressing steels are compared and variability in their actual properties is observed. Corresponding coefficients of recommended equations are given. It is the result that the influence on ultimate behavior of major variables such as type and amount of prestressing steel, the amount of nonprestressed tensile, compressive reinforcement, and the ultimate concrete compressive strain exists. Then we put an empasis on comparing the influence with code derived results. By results of this study, we could point out that if used. where the recommended code may lead to an unsafe design and what modifications may be needed to make the code suitable to the observed trends.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

파트너십에 의한 지하철 입구 공간의 쌈지공원 설계 및 시공

김승환,강현우,손용욱,박승범,남정칠,이기철,차민준 東亞大學校 建設技術硏究所 2009 硏究論文集 Vol.32 No.2

A pocket park is valued in securing green space in downtown and improving urban view in the aspect of natural and environmental values, and it signifies a lot as the center of local residents’ community and harmony as well. Since subway exits and surroundings that have high portions in taking up street space due to lack of green space in downtown aren't made full use of, valuable pocket park place. Dangni Pocket Park of subway exits is a park completed with cooperative works and partnership by students, specialists, administrative organizations, businesses and civilian organizations, etc. without support of special budget. The study site was finally chosen to the space between exit No.1 of Dangni subway station, after analyzing the surrounding circumstances, availability and accessibility of the space among the several subway station exits of Saha, Dangni, and Hadan Station in Busan Metropolitan city. For the designing process, The Citizens organization for Million Amenity Park performed the planning and project proceeding, and 19 design drafts were proposed during the class of landscape architecture in Dong-a University. Design review panel members discussed to select the best draft in practical and authentical, and the related experts reviewed and revised to present the final design plan. The construction was conducted was performed under the cooperation between the civil, authorities, and industrial organizations, among which Saha District office managed for the waste treatment and maintenance matters. The graduates of landscape architecture department of Dong-a University and related industrial enterprises supplied landscape materials and related labors, were supported by 20 members of GPM, one of clubs of Dong-a University volunteered durig the most of construction progress, completing the Pocket Park of subway exits through partnership.

약물 유해반응 보고지침 -임상시험의 안전성에 관한 정보 관리지침 -

지동현,김훈교,배진우,손동렬,김인범,전용관,박혜연 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

고혈압치료제의 in vitro및 in vivo 이용률간의 상관성 연구(Ⅱ)

서수경,강현구,조재민,박인숙,안미령,이선우,최흥석,유태무,손수정,이용복,양지선 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

의약풍이 생체내로 흡수되는_파정에서 생리학적 인자 및 제제학적 인자들에 의해 생체이용률이 달라져 약물의 흡수과정을 연구함으로써 약물의 생체이용률을 예측하는 것이 가능하다. 그러나 제제학적 측면에서 용출시험과 흡수과정인. 장관막 투과도 나아가서 생체이용률간의 띤구가 미흡한 상태이다. 따라서 약물의 흡수과정을 연구하벼 생체이용률을 예측하기 위하여 장관막 투과도 및 혈중농도사이의 상관관계를 예견할 수 있는 모델을 개발하고자 1999년도 연구사업으로 고혈압치료제중 베타-차단약 (아테놀올, 메토프롤올, 프라프라놀꼴)을 선택하여 웅출시험과 장관막 투과도계수를 측정하여 사람의 흡수을을 예측할 수 있는 장관막 투파도 모델을 확림하였고, 2000년도에는 계속사업으로서 각 약물에 대한 횐쥐에서의 생체이용를 파라메타를 측정하고 1999년도 연구사업결과에서 얻은 장관막 투과도 시험결과를 가지고 생체이용률과의 상관섞을 구하고자 하였다. 각 베타-차단약을 경구 및 정맥투여하고 시간별로 채혈한 후 분리한 혈장으로부터 각 약물에 대한 EfLC를 이용한 분석준건을 확지하여 혈중농도를 측정하고 생체이용률 파라메타(AUC, Cma, Tme, 등)를 구하였다. 횐쥐의 소장을 이용하여 diffusion chamber 법으로 측정한 장관막 투과도계수와 각 생체이용률 파라미터 사이의 상관성을 구찬 결과 양호한 상관관계를 보였다. 이와 같은 연구결과를 통하여 약물의 특성에 따라 동물의 장관막 투도. 모델을 이용하여 사람의 생체이용률도 예측할 수 있을 것으로 사료된다. A biopharmaceutics drug classification system for correlation f'H uf'fro dissolution and rH ui'ㄴo bio3vailabi3ity is proposed based on recognizing that drug dissolution andgastrointestinal permeability are the fundamental parameters controlling rate and extent of drugabsorption. The objective of this stud)· was to assess whether partition coefficient and intestinalPermeabilit)'can be rorrelateo with l'H vluo bioalFaifability. Beta-blockers were administeredorall? and intrauenousl)· to rats and pkarrnacokinetlc parameters were calculated. The goodcorre)ations between fermeability and log P (n~octanol/buffer) was demonstrated in previous ratexpenments performed in our laboratory. In this study, good correlations were obseFYedbetuTeen panitlon coefficient and permeabilit)·· or I'n ui'vo bioayilability These resuats indiEatethat rat intestinal perme3bilit3T model couBd be used to predict intestinal absorption ofbeta-blockeTs f'H uiuo.

A FIRM’S STRATEGY TO CONSUMER BEHAVIORAL DECISIONS: PERCEIVED OBSOLESCENCE AND THE TIMING OF REPLACEMENT

Yong Seok Sohn,Kun Woo Yoo 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7

Adding new attributes is the main strategy firms use to attract consumers in many industries, but the impact of new attributes may be ambiguous, as indicated by the results of several studies (Bertini, Ofek and Ariely, 2009; Griffin and Broniarczyk, 2010; Nam, Wang and Lee, 2012; Sun, Keh and Lee, 2012; Zhang and Fitzimons, 1999; Zhang, Kardes and Cronley, 2002). The demand for innovative, upgraded, and integrated products is higher than ever before, and firms’ ability to meet this demand is tenuous in many cases. Take the example of the iPhone, where the touch pad option is the new feature that overcomes the disadvantages of a regular keypad, and where other options such as SIRI and other convenient software technologies provide good reasons to purchase or upgrade a smart phone. Although the transition from keypad to touch screen is occurring rapidly in the technology market, many consumers still opt to utilize their old phones rather than upgrading. The alignability of the attributes of the smart phone may affect their decision-making. Self-regulatory factors moderate decision-making based on alignable and non-alignable attributes. Promotion and prevention self-regulation systems managed across separate mental accounts are involved consumer information flow process in the sense that alignable attributes engender risk aversion, whereas non-alignable attributes engender risk seeking (Zhou and Pham, 2004). More cognitive effort may be required to evaluate non-alignable attributes due to the absence of inferential references inherent in the newness of features (Nam et al., 2012; Sun et al., 2012). Accordingly, if there is no significant difference in alignable attributes between products, consumers will put more weight on non-alignable attributes (Brown and Carpenter, 2000). For high-technology products, if alignable attributes satisfy consumers’ perceived utility as weighed against the cost incurred, consumers may compare non-alignable attributes in order to justify their purchases. Even if non-alignable attributes are trivial, they may be important to the final decision. Based on evaluations of the latter, consumers can justify the purchase (Brown and Carpenter, 2000). Although non-alignable attributes may seem peripheral and complementary, they may contribute to the success of a product due to their novelty, uniqueness and role in simplifying the purchase choice (Carpenter, Glazer and Nakamoto, 1994). However, if consumers perceive that non-alignable attributes fundamentally affect product quality, they may infer that its alignable attributes are relatively inferior. This thinking process may result in a negative evaluation of the product (Simonson, Nowlis and Simonson, 1993). As mentioned earlier, consumers may associate non-alignable attributes with unnecessary costs (Brown and Carpenter, 2000). In the experiment of Bertini et al. (2009), consumers preferred the MP3 player with the BOSS earphone over the one with no other option, which led to a decrease in the willingness to upgrade the product. They do not evaluate non-alignable attributes in isolation, but may use those instrumentally. In the case of high technology products, when information about non-alignable attributes becomes available, ambiguity arises from the integration of distinctive features and functionalities, which are non-alignable attributes, and moreover from the integration of non-alignable attributes with alignable attributes. Consumer beliefs and attitude resulted from the mediating role of this ambiguity are formed holistically by non-selective attention for integral stimuli (alignable and non-alignable attributes) (Nosofsky, 1986, 1987). When consumers ambiguous towards a bundle of attributes, which is nothing but the product, they are inclined to interpret it positively (Bar-Hill and Budescu, 1995; Goldsmith and Amir, 2010). Consumers are hypothesized to exhibit innate optimism, being biased towards unforeseen benefits. They are even sensitive to the specific types of non-alignable attributes: central vs. peripheral attributes. Thus, in strategizing for product marketing purposes, non-alignable attributes should be positioned as peripheral factors rather than as central factors, especially in the early stages of product introduction. Hypothesis Development Consumers make judgments about the obsolescence of the products they currently use. Various factors influence the decision to upgrade. Obsolescence is a loss in value since the launch of a product, not because the product has become less useful, but because a new product with upgraded features and designs has become available to consumers (Bayus, 1991; Chung, Han and Sohn, 2012; Levinthal and Purohit, 1989). Consumers’ expectations about improvement in the new version are based upon two types of obsolescence that influence their willingness to upgrade (pay) for the new product: technological obsolescence and psychological obsolescence. Much research has been done (Bayus, 1991; Chung et al., 2012; Levinthal and Purohit, 1989); however, consumers’ strategic decision-making has not always been clearly understood. They may not know in advance what product to choose, or they may lack information to utilize during the buying process. In addition, technological progress is so rapid and uncertain that consumers may not be able to keep up with the novelty of new technologies. They may have difficulty selecting among alternatives that will be standard later in the market. Accordingly, although they may perceive the technological obsolescence of the product, they may not replace it until they feel psychologically justified in doing so. They may not intend to replace the product only for reasons of technological obsolescence due to loss of the sunk cost incurred by its replacement (Okada, 2006). While alignable attributes are more likely to be deterministic, functional and important, non-alignable attributes are more likely to be marginal, hedonic and trivial. Accordingly, consumers may form cognitive attitudes toward alignable attributes and expectations as to how these should change to become more useful. In other words, they may develop their own ideal level (point) for each alignable attribute as they become familiar with them. Thus, consumers experience uncertainty within a range unique to each individual. They judge the feasibility of a purchase insofar as it corresponds to their own ideal points. For example, when Microsoft upgraded from MS Office 2002 to MS Office 2007, the text menu-driven UI (user interface) was changed to become ribbon menu-driven (graphic). Many users of MS Office 2002 had difficulty using the upgraded functions of MS Office 2007. Frequently used features and options in the previous version, even such as cut and paste, were suddenly not easy to use, and consumers who upgraded to the next version were puzzled at the fact that they were unable to properly use the function they got used to. Complexity may be detrimental to ease-of-use judgment with inferred learning costs. Although consumers make inferences based upon their ideal points, the uncertainty involved in this process relates to cognitive referral. Since alignable attributes are representative of prevention, these engender risk aversion for consumers. Consumers who are primed with prevention-focus may prefer not to exert effort to find out how to use features which were easy to use in the previous version just for the sake of upgrading to the new product. Accordingly, uncertainty about ease of use of alignable attributes has a negative effect on consumers’ willingness to replace a product As more information on a product’s non-alignable attributes becomes available, consumers’ ambiguity about the updated product will decrease and their likelihood of replacement will decrease (Smith and Amir, 2010; Norton, Frost and Ariely, 2007: Bar-Hillel and Budescu, 1995; Krizan and Windschitl, 2007). In addition to technological obsolescence, curiosity and self-regulation in terms of the newness and novelty of a product may motivate consumers to replace a product. Existing consumers may be very curious about new information and non-alignable attributes, making every effort to process available information (Alba and Hutchinson, 1987; Maheswaran and Sternthal, 1990; Nam et al., 2012; Sujan, 1985). When non-alignable attributes become available, consumers do not look at them separately from the alignable ones with which the upgraded product is already equipped; instead, they evaluate the product holistically (Bertini et al., 2009). In an identification–classification task, subjects that were able to attend selectively to the relevant dimension and filter the irrelevant one for separable stimuli were unable to do so for integral stimuli. Non-alignable attributes directly affect consumers’ willingness (likelihood) to replace a product. Therefore, a mediating role of ambiguity is evident between non-alignable attributes and consumers’ willingness to replace the product. Thus, we present the following hypotheses: Hypothesis 1-1: When information on alignable attributes becomes available, consumers will be primed with prevention-focus. Hypothesis 1-2: When information on non-alignable attributes is available, consumers will be primed with promotion-focus. Hypothesis 2-1: If consumers are uncertain about the alignable attributes of a product, they will less likely purchase the updated version of the product. Hypothesis 2-2: If consumers are uncertain (ambiguous) about the non-alignable attributes of a product, they will more likely purchase the updated version of the product. Each individual tries to minimize the distance from a current state to a desired state by means of self-regulation (Higgins, Kruglanski and Pierro, 2003). The mode of self-regulation may be either locomotive or assessable. Assessment is a self-regulatory mode in which some objects and states are critically and analytically judged relative to desired means and goals in order to select the best among many alternatives (Kluglanski et al., 2000). Assessors intend to minimize the distance from the current state to the desired state by means of comparative processes to measure, construe and evaluate among alternatives (Higgins et al., 2003). Accordingly, they make cognitive efforts to compare and analyze the alternatives prior to the choice behavior. The other self-regulatory mode, locomotion, involves judging of objects and states with reference to a particular goal in the process of selecting alternatives (Kruglanski et al., 2000; Pierro et al., 2006). Because locomotors emphasize behavior and progress, they are quick to analyze the alternatives and direct in their selection. Locomotors are different from assessors, who select the best alternative via comparative processes. Locomotors try to select the best alternative realistically and heuristically to achieve their goals. They may not commit to analytical assessment of all possible problems in the process. In the process of evaluating alternatives, assessors focus on all attributes rather than on some particular attributes. They continuously try to assess both alignable and non-alignable attributes. By contrast, locomotors want to achieve a particular goal rapidly. When they perceive technological obsolescence, they may rely on information about alignable attributes because they are eager to benefit from improved features and functions. In the same vein, when they perceive psychological obsolescence, they may rely on information about non-alignable attributes because of the differences in value of these attributes from those of the existing product. Therefore, we offer the following hypotheses: Hypothesis 3: When assessors evaluate an updated product, they will put more weight on non-alignable attributes than on alignable attributes. Hypothesis 4: When locomotors evaluate an updated product, they will depend upon attribute information corresponding to the two types of obsolescence. EXPERIMENT 1 Method Experiment 1 explores consumers’ regulatory focus which would be differently primed either with alignable attributes or with nonalignable attributes (H1 and H2). And it explores consumers’ purchase intention via the amount of information (low-information vs. high-information) and regulatory modes (locomotion vs. assessment. A pretest was conducted with a separate sample (n=64) to ensure that the product profile used in the experiment matched the situation where participants perceive alignable attributes to be deterministic, functional and salient, and where they perceive nonalignable attributes to be peripheral, hedonic and novel. We picked the external HDD that participants associated with salience and newness. In the main experiment, two hundred seventy one participants read information about the external HDD and then answers on the alignable and nonalignable attributes of this product. The between-subject experimental design consists of information type (alignable vs. nonalignable attributes) x information amount (low-information vs. high-information). Results We examined that consumers will be primed with different regulatory focus (H1 and H2) upon the type of information via a gap analysis and a mediated regression analysis. The test results were that respondents exposed to the information type of alignable attributes would be primed with prevention-focus (4.60) than with promotion-focus (4.20) (t = -3.180, p < .001), and that respondents exposed to the information type of nonalignable attributes would be primed with promotion-focus (4.44) than with prevention-focus (3.99) (t = -2.746, p < .05). Next, the type of information was treated as a dummy variable, where it takes values of “0” for nonalignable attributes and of “1” for alignable attributes. Respondents’ dominant regulatory focus was set to be the value of prevention which was subtracted from the value of promotion. The primed regulatory focus fully mediates between the type of information and purchase intention (Sobel Z-score = -3.827, p < .01). That is, if consumers are exposed to the information type of alignable attributes, they will be primed with prevention-focus, which will negatively affect consumers’ purchase intention. Accordingly, Hypothesis 1-1 and 1-2 were supported. Furthermore, we examined the differential effect on purchase intention via a 2 (type of information) × 2(amount of information) between-subjects ANOVA (H1-2 and H2-2) as in Figure 2. In the case of respondents exposed to alignable attributes, the purchase intention was higher for certain information (3.75) than for uncertain information (3.20) (t = 2.077, p < .05), whereas in the case of respondents exposed to nonalignable attributes, the purchase intention was higher for uncertain information (4.48) than for certain information (3.81) (t = 2.478, p < .05). Prior knowledge and involvement on the stimulus were controlled as covariates, and respondents were divided into groups by means of the information type and the information amount. The interaction between the variables was investigated (F(1, 271) = 13.413, p < .01). Accordingly, H2-1 and 2-2 were supported. Finally, we examined the differential effect on purchase via 2 (regulatory mode) × 2 (type of information) between-subjects ANOVA (H4 and H5) as in Figure 3. Regulatory mode was dichotomized into locomotion and assessment by the median of values of assessment subtracted from those of locomotion. In the assessors’ case, a difference between the purchase intentions by means of the type of information – alignable attributes (3.60) and nonalignable attributes (3.73), was not found (t=-.533, p > .10). Hypothesis 3 was rejected. On the other hand, in the locomotors’ case, the purchase intention of respondents exposed to the information type of nonalignable attributes (4.53) would be higher than that of those exposed to the information type of alignable attributes (3.38) (t = 3.826, p < .01). Accordingly, hypothesis 4 was supported. Prior knowledge and involvement on the stimulus were controlled as covariates, respondents were divided into groups by means of regulatory mode and the information type. The interaction among purchase intention, regulartory mode and the information type (F(1,271) = 7.647, p < 0.01).

Implications for Modulation of Expression and Activity of Endothelial Nitric Oxide Synthase and Caveolin-1 by the After-treatment of a Hepatic Protective Antioxidant Mixture Silymarin on the in Carbon Tetrachloride-induced Cirrhotic Rat Livers

( Yong Kyun Cho ),( Byung Ik Kim ),( Tae Woo Yoo ),( Se Yong Oh ),( Jung Ho Park ),( Dong Il Park ),( Hong Joo Kim ),( Chong Il Sohn ),( Woo Kyu Jeon ),( Seung Duk Ryu ),( Chang Shin Park ) 대한간학회 2005 춘계 학술대회 Vol.11 No.-