전자계가 동식물에 미치는 영향 ( Research on the Biological Effect of Electromagnetic Fields )

이기철,이홍식 대한전자공학회 1987 특정연구 결과 발표회 논문집 Vol.- No.-

Fluoxetine이 Schedule-Induced Polydipsia가 유발된 백서 뇌에서 Tyrosine Hydroxylase 발현에 미치는 영향

이기철,이정호,최영민,정주호,정홍경,이용민,김도형,이대환 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

연구목적: Fluoxetine은 serotonin을 매개하여 간접적으로 dopamine 신경전달기능을 억제한다고 추정되고 있다. 또한 운동장애에서 운동기능의 악화를 유발한다고 알려져 있다. 그러나 신경세포체에서 fluoxetine이 dopamine에 어떠한 영향을 주는지는 아직까지 확실치 않다. 저자들은 schedule-induced polydipsia를 유발시킨 백서 뇌의 흑질, 복부피개영역, 미상핵에서 tyrosine hydroxylase(TH) 발현이 저하됨을 발견하였다. 이를 통해서 fluoxetine이 백서 뇌의 dopamine 기능에 긍정적인지 혹은 부정적인지를 규명하고자 하였다. 방법: 4주간의 schedule-induced polydipsia 과정을 거친 백서에서 면역죄치화학적인 방법으로 흑질, 복부피개영역, 미상핵의 tyrosine hydroxylase 발현이 저하됨을 확인한 후, 실험동물들에게 fluoxetine 10mg/kg를 3주간 복강내 주사하였다. 실험백서들을 희생시켜 뇌 조직을 적출하여, TH 면역조직화학 염색법을 이용하여 흑질, 복부피개영역, 그리고 미상핵의 TH 면역반응세포를 관찰하고 이를 정상백서와 비교하였다. 결과: 1) 다갈증이 유발된 백서의 흑질, 복부피개영역, 미상핵에서 tyrosine hydroxylase 발현이 정상백서 보다 저하됨을 관찰하였다. 2) 3주간에 걸친 fluoxetine 투여후 흑질, 복부피개영역, 미상핵의 tyrosin hydroxylase 발현이 다시 증가하는 소견을 보였다. 결론: Fluoxetine 만성투여가 흑질, 복부피개영역 그리고 미상핵의 tyrosin hydroxylase를 증가시키는 소견을 얻었다. 이러한 결과는 임상에서 dopamine 결핍과 연관된 질환들에서 fluoxetine을 만성투여하면 운동기능을 포함한 증상들의 개선을 가져올 수도 있다고 추정된다. Objective: It has been suggested that fluoxetine inhibits the dopaminergic neurotransmission by serotonergic mediation. And also, it has been shown to inhibit synthesis of DOPA in dopamine-rich areas of the rat forebrain. These dopamine-antagonistic capacity of fluoxetine is only supported by anecdotal report that the increased amount of motor disability in patients with idiopathic Parkinson's disease after exposure to fluoxetine. However, there is still no evidence of the direct effect of fluoxetine on dopaminergic neuronal cell body in the substantia nigra, VTA, caudate & putamen. This study was designed to evaluate the effects of fluoxetine in rat brain which showed decreased numbers of dopaminergic neuronal cell body induced by schedule-induced polydipsia(SIP). Method: We incidentally found that 4 weeks of schedule-induced polydipsic rats revealed the suppression of tyrosine hydroxylase expression in the substantia nigra, VTA, caudate & putamen with the immunohistochemistric measures. After 3 weeks of intraperitoneal injection of 10mg/kg of fluoxetine to the schedule induced polydipsic rats, the tyrosine hydroxylase expression was also measured with immunohistochemistry. We compared the tyrosine hydroxylase expression among the normal control, the polydipsic rats, and the rats with fluoxetine treatment. Results: 1) By contrast with the control, the polydipsic rats revealed the evidence of decreased tyrosine hydroxylase expression in the substantia nigra, VTA, caudate & putamen. 2)After daily injection of fluoxetine for 3 weeks, the polydipsic rats showed increment of tyrosine hydroxyase expression in those areas. Conclusions: In previous studies, a great deal of results suggest that fluoxetine negatively influence the dopaminergic systems indirectly via serotonergic activation such as inhibition of dopamine synthesis or transport system. Although our results are obtained from rodents, we suggest that fluoxetine directly and positively enhance the dopamine system in the substantia nigra, VTA, caudate & putamen. The chronic adminstration of fluoxetine may be helpful to dopamine-depleted condition in clinical situations. We anticipate the replication studies of our findings and well-controlled clinical trial.

UIS 기반의 u-City 구축 전략

이기철,이병철 東亞大學校 建設技術硏究所 2005 硏究論文集 Vol.28 No.2

In this study, the concept of u-City was suggested based on the data, information and technology of UIS(Urban Information System). In the age of ubiqutous, information oriented network is essential in the city. At first, we introduced the background and characteristics of ubiqutous age. U-city is an ideal comcept for nation's growth. Based on the intelligent, innovative and integrated information, physical city is transformed into the cyber space which can manage city governance better. The strategy to implement the u-City was described for this objective.

유산소 운동이 중년기 남성들의 신체조성과 체력 및 호흡순환기능에 미치는 효과

이기철,주영호 부산 외국어 대학교 2002 外大論叢 Vol.24 No.-

The purposes of this study were to examine about how regular exercise contributed to middle-men's health and represent effective materials to maintain and promote middle-men's health through the study on an element of Body Composition, a condition of Physical Strenght and Cardiopulmonary and offer basic materials of appropriate exereise prescription to manage physical strength's promotion and more healthy life in middle-men of forty. Subjects measured aerobic exercise of an hour of a day. three times a week, for 12 weeks. The results of this study were as follows; 1. Body Composition In Body Composition, Subscapular Fat significantly decreased after exercise, and there were significant differences in %Fat and Fat(p=.05). 2. Physical Strength In Physical Strength, there were no significant differences before and after exercise in Grip Strength, Trunk Flexion, Closed Eyes One-Foot Balance. Standing Broad Jump. There were significant differences in Back Strength, Trunk Extension, Side Step Test, Sit-Up(p=.05. p=.01). 3. Cardiopulmonary In Cardiopulmonary, there were significant differences in FVC, MVV(p=.05), and there were no significant differences at Rest. In Cardiopulmonary during maximum exercise, there were significant differences in VE, VT, BF, VO2max, VCO2(p=.05, p=.01, p=.001) There were significant differences in exercise distance and duration after exercise(p=.05)

初等 實科敎育의 變遷과 發展方向

李基哲,洪鍾雲 춘천교육대학교 새마을연구소 1990 새마을 교육연구 Vol.3 No.-

스포트 지도자의 리더십 유형에 대한 체계적인 고찰과 이론적 모형 탐색에 관한 연구

이기철 釜山 外國語 大學校 1998 外大論叢 Vol.18 No.2

The objective of this study is to come up with the opportunity to give a profound thought to the traditional and authoritaive practice of corporal punishment in terms of the behavioual attiudes of instructors and players toward the punishment inflicted on players in the course of sports activites, psychological and sentimental change and problems with the viewpoint twoard the matter at hand. As a consequence, the following have been brought up. (1) The change of point of view twoard corporal punishment is in urgent need so as to strike the balance between player's right and instructor's authority. (2) The methods of corporal punishment in the context of sports training for the purpose of physical and mental fortification should be devised. (3) In case of inevitable punishment, see to it that the body parts that can undergo less impact such as hips are chosen, and that you make the player understand why you are obliged to take such acts lest the player should experience mental shock. (4) The instructions on a humanitarian basis need carrying out through the removal of traditional value or prejudice that corporal punishment proves to be of help to the improvement of players' sports skills. Besides, the effectiveness should be checked out. (5) The instructors who inflicted corporal punishment on players came up regretting about their behaviors. Given the remarks, instructors must come up with more flexible, positive and productive methods. For instance, the instructors ought to try love, encourage and support their players, putting their team into unity. Furthermore, instructors need to realize their generosity results in players'. In conclusion, the anachronistic, authoritative point of view of sports instructors toward corporal punishment is required to change given the current social trened to avoic violence and the demand for players' rights.

고교생의 체육수업에 대한 자기평가 분석

이기철 釜山外國語大學校 1999 外大論叢 Vol.19 No.5

The purpose of this study is to clarify the self-evaluation method of physical education classes by students. Some efficient instruments for the synthetic evaluation have already been developed. However, the reliable instrument for the self-evaluation seems to be missing. Therefore, we intended to develop a convenient and effective instrument for self-evaluation of physical education class which can be used in each teaching unit. The subjects were 426 students from 4 senior high schools. Factor analysis, multiple regression, and oneway ANOVAis used to estimate relationship between each variables. These results were as follows ; 1) The self-evaluation factors exist three factors representing dimensions of self-evaluation ; motivation of learning, cooperation, and outcome of learning. 2) When the self-evaluation factor scores are compared for differences in each senior high schools, mean scores differ significantly for all. 3) When the self-evaluation factors are compared for the result of practical teaching, three factor scores showed significant and positive relationships with those of the comprehensive evaluation items concerning good or effective instruction. Thus, the factors were interpreted as effective standards for self-evaluation.

유산소 운동이 비만여성의 심폐기능 및 혈청지질에 미치는 영향

이기철,박상갑,윤미숙 부산외국어대학교 정보과학연구소 2000 情報科學論集 Vol.2 No.-

The purpose of this study was to investigate the changes of body composition, circulorespiratory functions, serum lipids after 12weeks walking exercise. Subjects were composed of ten middle-aged women. VO2max was determined for each subjects by administering a treadmill exercise test. Subjects were trained during 12weeks(80m/min, 5 frequencies /week, 1 hour). The result of this study are as follows ; 1.Weight and %fat were decreased to 4.2kg and 6.5%, respectively, after 12weeks walking exercise. 2.Circulorespiratory function was improved because of increasing in VO2max, VO2max/kg after 12weeks walking exercise. 3.Total cholesterol, Low density lipoprotein cholesterol and Triglyceride were decreased to 39.3mg/㎗, 25.6mg/㎗ and 36.5mg/㎗ respectively after 12weeks walking exercise. 4.Atherogenic Index was decreased to 1.45 after 12weeks walking exercise. In conclusion, 60min walking training was shown to maintain aerobic capacity which decrease according to aging and positive influence on preventing and improving in low HDL and hear disease to be cause by the lack of exercise.

유ㆍ무산소 유영훈련이 혈중 Triglyceride 농도 변화에 미치는 영향

이기철,오성기 부산 외국어 대학교 2000 外大論叢 Vol.21 No.1

This study has been analyzed by variation in blood tryglyceride density from anaerobic and aerobic swimming training of the Rats. The experimental animals have used of Sprague-Dawley 25 and were practiced 12 weeks of swimming training, this experimental animals were assigned to 5 Group: one was control group(untraining group), another group was experimental group(anaerobic training 10min, 30min, aerobic training 60min, 90min training group). The results were as follows: 1) The triglyceride density of control group was the Mean=43.00mg/dl, SD = ±17.79 and the 10min group of the Mean=35.00mg/dl, SD= ±10.42mg/dl and the 30min group Mean=30.25mg/dl, SD= ±7.18mg/dl, and the 60min group Mean=24.76mg/dl, SD=±8.95mg/dl, and the 90min group mean=14.00mg/dl, SD= ±3.00mg/dl. 2) The tryglyceride density of the anaerobic 10, 30min group were decrease and of the aerobic 60, 90min group were decrease

여는 시-농로

이기철 우리신학연구소 1997 갈라진 시대의 기쁜소식 Vol.- No.295