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이용복,장민환 경희대학교 자연과학종합연구원 1998 자연과학논문집 Vol.4 No.-
경희대학교 천문대와 소백산천문대의 망원경을 이용하여 접촉쌍성계인 ER Orionis를 B, V, 및 R의 필터에 따라 CCD 관측을 수행했다. 관측에서 3개의 주극심시각과 2개의 부극심시각 얻었고, 이어 광도곡선을 구했다. 본 연구에서는 본 관측에서 얻어진 광도의 변화 경향을 분석하여 다른 연구자들이 구한 결과와 상호 비교했다. 이 결과 본 연구의 대상인 접촉쌍성계는 표면에 강한 활동이 일어나고 있으며, 이 쌍성계의 주기 변화도 이 활동과 밀접한 관련성이 있는 것으로 예상된다.
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이용복,강현아,김환호,김세미,윤화,조혜영,오승열,최후균 한국약제학회 2006 Journal of Pharmaceutical Investigation Vol.36 No.5
A rapid, selective and sensitive reverse-phase HPLC methods for the determination of atenolol and chlorthalidone in human serum and whole blood were validated, and applied to the pharmacokinetic study of atenolol and chlorthalidone combination therapy. Atenolol and an internal standard, pindolol, were extracted from human serum by liquid-liquid extraction, and analyzed on a -Bondapak C18 10-mm column in a mobile phase of methanol-0.01 M potassium dihydrogenphosphate (30:70, v/v, adjusted to pH 3.5) and fluorescence detection (emission: 300 nm, excitation: 224 nm). Chlorthalidone and an internal standard, probenecid, were extracted form human whole blood by liquid-liquid extraction, and analyzed on a Luna C18 5-m column in a mobile phase of acetonitrile containing 77% 0.01 M sodium acetate and UV detection at 214 nm. These analysis were performed at three different laboratories using the same quality control (QC) samples. The chromatograms showed good resolution, sensitivity, and no interference by human serum and whole blood, respectively. The methods showed linear responses over a concentration range of 10-1,000 ng/mL for atenolol and 0.05-20 g/mL for chlorthalidone, with correlation coefficients of greater than 0.999 at all the three laboratories. Intra- and inter-day assay precision and accuracy fulfilled international requirements. Stability studies (freeze-thaw, short-, long-term, extracted sample and stock solution) showed that atenolol and chlorthalidone were stable. The lower limit of quantitation of atenolol and chlorthalidone were 10 ng/mL and 0.05 g/mL, respectively, which was sensitive enough for pharmacokinetic studies. These methods were applied to the pharmacokinetic study of atenolol and chlorthalidone in human volunteers following a single oral administration of Hyundai Tenoretic?? tablet (atenolol 50 mg and chlorthalidone 12.5 mg) at three different laboratories.
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Oak Tree Canker Disease Supports Arthropod Diversity in a Natural Ecosystem
이용복,곽연식,안수정,박정규,김진우,한상조 한국식물병리학회 2014 Plant Pathology Journal Vol.30 No.1
Microorganisms have many roles in nature. They mayact as decomposers that obtain nutrients from deadmaterials, while some are pathogens that cause diseasesin animals, insects, and plants. Some are symbionts thatenhance plant growth, such as arbuscular mycorrhizaeand nitrogen fixation bacteria. However, roles of plantpathogens and diseases in natural ecosystems are stillpoorly understood. Thus, the current study addressed thisdeficiency by investigating possible roles of plant diseasesin natural ecosystems, particularly, their positive effectson arthropod diversity. In this study, the model systemwas the oak tree (Quercus spp.) and the canker diseasecaused by Annulohypoxylon truncatum, and its effectson arthropod diversity. The oak tree site contained 44oak trees; 31 had canker disease symptoms while 13were disease-free. A total of 370 individual arthropodswere detected at the site during the survey period. The arthropods belonged to 25 species, 17 families,and seven orders. Interestingly, the cankered treeshad significantly higher biodiversity and richnesscompared with the canker-free trees. This study clearlydemonstrated that arthropod diversity was supportedby the oak tree canker disease.
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AHP/ANP에 의한 고객 지향적 마케팅 의사결정 방법
이용복,박상기,윤덕균,곽병호 한국고객만족경영학회 2006 고객만족경영연구 Vol.8 No.1
The Customer Satisfaction which effects directly the performance of almost all companies. Therefore, it is very important for a company to reflect totally market environment which can be changed fast and diversely by customer requirements. In spite of many studies on the marketing decision, it has been rarely applied for the quantitative method and result of customer satisfaction index assessment in the marketing decision process. This study proposed a quantitative customer-oriented marketing decision method by reevaluating the customer satisfaction index. This method converts the customer satisfaction index into the ranks and weights the priorities using the reverse median rank, and calculates the priorities of the alternatives in the concept of the AHP(Analytical Hierarchy Process) and ANP(Analytic Network Process) approach which permitting the inner-dependent relationship between hierarchy and decision factors in the decision process. Moreover, we propose a method which represents efficiently the customer satisfaction index so that the suggested method in this study becomes customer-oriented marketing decision. 기업의 성과에 직접적인 영향을 미치는 고객만족은 기업의 궁극적인 목표가 되어가고 있다. 고객만족 달성을 위해서는 고객의 요구를 정확히 파악하여 종합적으로 분석할 수 있는 마케팅 전략수립 기법이 절대적으로 필요하다. 본 연구에서는 고객만족 경영의 평가지표로서 일반적으로 활용되고 있는 고객만족도를 분석함으로서 고객지향적인 마케팅 의사결정을 할 수 있는 계량적 방법을 제안했다. 이를 위해, 고객만족도를 구성하는 요소들을 상호 관련성에 따라 재분류한 뒤 역누적 메디안 랭크를 이용하여 만족도를 상대적 중요도로 환산하였다. 이를 바탕으로 AHP를 적용하여 대안에 대한 상대적 중요도를 산출하였으며, 또한 요소들 간에 상호 의존성을 허용함으로서 AHP보다 일반적인 접근방법을 제시하고 있는 ANP기법을 적용한 중요도 산출 결과를 비교하였다. 결론적으로 고객만족 경영의 실현을 위해 고객의 평가를 의사결정에 반영할 수 있는 계량적 의사결정 시스템 구축에 대한 중요성을 상기시켰다는데 의의가 있다.
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