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      • KCI등재

        랫드의 화상모델에서 전복껍질과 참기름의 치료효과

        남상윤,이범준 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.2

        This study was performed to investigate effect of a mixture of ear shell ash and sesame oil on bum in a Sprague-Dawley rat model. Sixty male rats were assigned to 3 experimental groups including negative and positive control groups, and a test material group. The test compound was applied to formally once a day f3r 7 days. Distilled water was applied as a relative positive control. After dermal applications f3r 3, 5, and 7 days, blood hematology and skin histopathological examination were performed. Inorganic compounds in ear shell ash was mainlycalcium oxide(92%). The body weights of positive control rats were significantly low at day 3, 5, and 7 as compared with negative control and test material groups. There was no significant difference in body weight between negative control and test material groups throughout the experimental period. WBC counts in both positive control and test material groups were higher than those in negative control group, indicating progress of inflammatory reaction. In differential leucocyte count, panulocytes including neutrophils and eosinophils were higher in positive control and test material groups than negative control group. Hemoglobin and hematocrit values were lower in homing model rats, probably resulting from hemorrhage in dermis. Skin histopathology showed severe full thickness coagulative necrosis in epidermis and dermis, hemorrhage and infiltration of leucocytes in dermis in both positive control and test material groups throughout the experimental period. These results indicate that the test materials, ear shell ash plus sesame oil, moderately ameliorate homing probably concerning to process of skin injury repair including inflammation and fibrosis

      • KCI등재후보

        당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

        한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

        Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

      • PWM을 이용한 트랙터 부착작업기의 자세제어

        이성범,이홍주,황성준 안성산업대학교 2002 論文集 Vol.34 No.-

        This study was conducted to control the posture of implement attached to tractor, which could make important effects on the working performance and accuracy. A tool bar, should be attached to the 3-point hitch, was designed to control the posture of implement by differentiating distances between one upper link and two lower links independently and simultaneously. By using PWM control method, the hydraulic fluid quantity was controlled proportionally according to the change of duty ratio with a high speed electronic solenoid valve. Computer simulation and fundamental test were also conducted for the developed posture control system using AMESim analysis tool The results of this study could be summarized as follows : 1. According to the results of computer simulation, major design parameters such as PWM control frequency, control agin, orifice diameter, and fluid pressure were determined as 30㎐, 1.5, 1.8㎜, and 10MPa, respectively. Time constant to make 100㎜ of stroke in load direction was about 0.55 seconds. 2. The tool bar, which was consisted of hydraulic cylinders and metal guides, was fabricated and tested for the performance of over all system. 1.6 seconds of response time of the control system was needed at inclination of 22°, and the performance of the posture control system was best at 150MPa of relief pressure, 1.5 of control gain, 20㎐ of PWM control frequency, and 2.2㎜ of orifice diameter, which did not represent considerable difference in compare with the results of computer simulation.

      • 공공건설프로젝트에서 효율적인 건설분쟁처리에 대한 연구

        이상범,조영준,김정길 동의대학교 산업기술개발연구소 2005 産業技術硏究誌 Vol.19 No.-

        A In Korea when change order was occurred, contract amount may be adjusted according to Government Contract Act. If the requirement of privy is fully accepted, conflict can't arise. Because of a misunderstanding and misappropriation of contract, a difference between the contract condition and job site, an errors & omissions of the design document, the contract disputes has been increased since the Seoul 2nd Metro Project claims alleged by 6 Contractors at Feb. 1998. To mitigate and to resolve effectively construction dispute, training of construction participants, introduction of coercive arbitration clause in public construction, adaption of the lowest bidding system, participation of construction engineer in arbitration process were suggested in this paper.

      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • 성인에서 발병한 과면역글로불린 E 증후군 1예

        이재천,박주상,윤지열,정두련,문희범,우준희,류지소 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

        과민역글로불린 E 증후군은 영유아기부터 반복적인 부비동, 호흡기감염 및 농양의 형성, 습진성 피부 질환 및 혈청 면역글로불린 E의 상승을 보이는 드문 질환이다. 특징적으로 농양은 발열이나 균혈증을 동반하지 않으며, 포도상구균이 흔한 원인균이며, 배농 및 항균제 정주로 효과적으로 치료된다. 향후 병태생리 및 치료에 대한 연구가 필 요하다. 저자들은 성인기에 발병한 반복적인 피하 농양 형성, 습진성 피부질환, 혈청 면역글로불린 E의 상승 등으로 과면역글포블린 E 증후군으로 진단된 증례를 국내 최초로 보고하는 바이다. Hyperimmunoglobulin E syndrome, rarely reported, is a syndrome of hyperimniunoglo-bulinemia E. eczematous skin lesion, and recurrent staphylococcal infections on respiratory system and skin with abscess formation, mostly from early in life. The abscess is not accompamed with fever and bacteremia, that is a characteristic 'cold abscess' We report a case of 56 year-old woman who manifested this syndrome from adulthood. with the review of literatures.

      • 다양한 함불소가스들의 고비점 용매에 관한 용해도 측정 및 엑막에 의한 분리

        최평호,이상학,김철웅,김범식,김광주,이정민,박인준 한국공업화학회 2002 응용화학 Vol.6 No.2

        The solubility of various fluoro-gases in high boiling-point solvents, n-Cnh_2n+_1OH(6<n<10)and ionic liquids(+ ions: 1-Buty 1-3-methy1-imidazolium, 1-Ethy1-3-methy1-imidazolium, - ions:BF_4, PF_6, S_6F_6, F_6O_4S_6) were measured at temperatures from 0 to 30℃, at total pressures up to 4 bat Solubility increased significantly with the decrease of n in n-Cn_2N+OH and showed no such a difference in the types of ionic liquids, Especially, the solubility of R22 gas in these solvents increases rapidly with increases in pressure and decreases in temperature, whereas other fluoro-gases were showed a little solubility Liquid-supported membranes were prepared with these solvents and polymer matrix and were applied to the separation of fluoro-gases including R22 gas. A high permeability and selectivity were exhibited in R22 gas against other fluoro-gases.

      • 서울의 PPNG 발생 빈도(1991-1992)

        김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

        The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

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