서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響

Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.

Antioxidant Activity and Whitening Effect of Lindera erythrocarpa Extract

Min ?Chul Kang,Ryeo Kyeoung Ko,Ju-Yeop Lee,Haeng-Bum Kim,Bong-Seok Kim,Jong-Heon Han,Seong-Hyun An,Gi-Ok Kim 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.10

Fast Fabrication of Sub-200-nm Nanogrooves Using Liquid Crystal Material

Kim, Dae Seok,Cha, Yun Jeong,Gim, Min-Jun,Yoon, Dong Ki American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.18

<P>Self-assembly of soft materials attracts keen interest for patterning applications owing to its ease and spontaneous behavior. We report the fabrication of nano grooves using sublimation and recondensation of liquid crystal (LC) materials. First, well-aligned smectic LC structures are obtained on the micron-scale topographic patterns of the microchannel; then, the sublimation and recondensation process directly produces nanogrooves having sub-200-nm scale: The entire process can be completed in less than 30 min. After it is replicated using an ultraviolet-curable polymer, our platform can be used as an alignment layer to control other guest LC materials.</P>

Methylmethacrylate Monomer의 가토 신장기능에 미치는 영향 : Effects of Methylmethacrylate Monomer on the Renal Function in Rabbits

김민형,장석종 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.2

Relating to toxicity of methylmethacrylate monomer, there are many evidences of pathological changes, ie. parenchymal degeneration in pulmonary, hepatic, and renal tissue of animal with high dosage. But the reports about the effects of methylmethacrylate monomer on renal function are rare. Therefore the author intended to investigate the effects of methylmethacrylate monomer on parameters of renal function. Experimental dosages of methylmethacrylate monomer were 0.1㎕/min and 0.25㎕/min, of which didn't cause the arterial hypotension. The infusion was perfermed at a rate of 30 ml/hr for 1 hour. During the one hour periods of administration of methylmethacrylate and recovery proces blood and urine samples were collected and analyzed. Plasma clearances of substances various were obtained by the measuring the plasma and urine concentrations of inulin, PAH, osmolarlty sodium and potassium. The results were summarized as follows. 1. Glomerular filtration rate and renal plasma flow were not affected at a dose of but tended to decrease at a dose of 0.25ul/min of methylmethacrylate monomer. 2. Urine flow was reduced significantly (p<0.05) by methylmethacrylate monomer. 3. Urine osmolarity was increased significantly (p<0.05) by methylmethacrylate monomer. 4. Negative free water clearance was increased significantly (p<0.05) by methylmethacrylate monomer. 5. Osrnolar clearance and sodium and potassium reabsorption rate were not affected significantly by methylmethacrylate monomer. From the above results, it was suggests that methylmethacrylate monomer caused the reduction of urine flow through enhancement of tubular free water reabsorption and partially affecting the GFR and RPF.

Alendronate의 뼈모세포를 통한 뼈파괴세포 형성 억제 기전

김현진,김민석,김태성,이은주,박하옥,김백윤,김선헌 대한해부학회 2003 Anatomy & Cell Biology Vol.36 No.6

Associations of serotonergic genes with poststroke emotional incontinence

Kim, Jae‐,Min,Stewart, Robert,Kang, Hee‐,Ju,Bae, Kyung‐,Yeol,Kim, Sung‐,Wan,Shin, Il‐,Seon,Kim, Joon‐,Tae,Park, Man‐,Seok,Cho, Ki‐,Hyun,Yoon, Jin‐ John Wiley Sons, Ltd 2012 INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY Vol.27 No.8

<P><B>Objectives</B></P><P>Poststroke emotional incontinence (PSEI) has been associated with serotonergic dysfunction. Polymorphisms of serotonin transporter (5‐HTT) and serotonin 2a receptor (5‐HTR2a) genes may regulate serotonergic signaling at brain synapses, and this study was to investigate associations with PSEI in an East Asian population.</P><P><B>Methods</B></P><P>In 276 stroke cases, PSEI was diagnosed by Kim's criteria. Covariates included age, gender, education, history of depression or stroke, current depression, and stroke severity and location. Genotypes were ascertained for 5‐HTT gene‐linked promoter region (5‐HTTLPR), serotonin transporter intron 2 variable number tandem repeat, 5‐HTR2a 1438A/G, and 5‐HTR2a 102 T/C. Associations with PSEI were estimated by using logistic regression models, and gene–gene interactions were investigated by using the generalized multifactor dimensionality reduction method.</P><P><B>Results</B></P><P>PSEI was present in 37 (13.4%) patients. The 5‐HTT gene‐linked promoter region <I>s</I>/<I>s</I> genotype was independently associated with PSEI. No associations with STin2 VNTR and 5‐HTR2a genes were found, and no significant gene–gene interactions were identified.</P><P><B>Conclusions</B></P><P>Stroke patients with 5‐HTTLPR <I>s</I> allele had higher susceptibility to PSEI, which underlines the potential role of serotonergic pathways in its etiology. Copyright © 2011 John Wiley & Sons, Ltd.</P>

위에 발생한 유암종 (Carcinoid Tumor) : 1예 보고

김남재,김진희,이경태,서광식,정현용,이승민,김석현,이병석,이헌영 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.3

A carcinoid tumor of the stomach is uncommon, has no clinical symptoms, and is regarded as a benign. It is also incidentally found in most cases. 48-year-old woman with gastric carcinoid tumor was admitted. She had suffered from a anorexia and a dry mouth for 4-months. A gastroscopy revealed a polypoid mass on the greater curvature of the mid-body of the stomach which was subsequently thought to be an adenocarcinoma. An endoscopic mucosectomy revealed however, that it was a carcinoid tumor. A case of carcinoid tumor of the stomach is here by presented with a brief literature review.

The Theology of Images in the Reformation

Min?Seok Kim 한국기독교학회 2016 한국기독교신학논총 Vol.101 No.-

교회 역사는 건축, 음악, 그림, 캘리그라피, 드라마, 조각, 영화, 스테인드글라스 등과 같은 예술적이고 기술적인 시각 매체 혹은 수단들을 통해서도 복음이 사람들에게 전달되어 왔음을 알려주고 있다. 더 나아가 현대 사회에서는 시각 이미지의 긍정적 가치와 의미가 더욱 대두되고 있다. 그 결과로 현대 교회들은 영상, 그림, 그리고 드라마와 같은 시각 이미지들을 설교와 예배에 대한 보조 도구들로 사용하기도 한다. 이러한 상황은 개신교 전통의 현대교회들을 위해서 개신교 신학 안에서 이미지에 대한 긍정적인 신학의 추구와 발전을 요구하고 있다. 그러나 많은 개신교회와 개신교 목회자들이 개신교 신학에는 시각 이미지에 대한 부정적 관점만 있을 뿐이라고 추정하는 것처럼 보인다. 그리고 이러한 단정적 추론은 개신 교회에서 경건과 예배를 위해 사용되는 시각 이미지에 대해 긍정적인 신학을 추구하고 찾는 데 걸림돌로 작용하고 있다. 이러한 상황 속에서 본 연구는 개신교 신학들 중에서도 이미지에 대한 긍정적 관점이 있는지를 찾고자 한다. 이 목적을 수행하기 위해 본 논문은 먼저 중세 후기의 이미지 오용을 다루고, 그 후에 세명의 종교 개혁자들(안드레아스 보덴슈타인 폰 칼슈타트, 마르틴 루터, 그리고 장 칼뱅)의 관점을 분석한다. 칼슈타트는 종교 개혁 진영에서 맨 처음으로 급진적 성상 파괴 운동을 공식적으로 시작했다. 그리고 루터와 칼뱅은 여전히 개신교 전통의 현대 교회들에 영향력을 행사하고 있다. 필자는 이러한 이유 때문에 16세기의 종교 개혁가들 중에 위에 언급된 세 명의 종교 개혁자를 선택했다. Church history has shown that the Gospel has been communicated and transmitted to people through artistic and technological media or ways such as architecture, music, paintings, calligraphy, drama, sculpture, movies, stained glass, etc. Moreover, in modern society, the visual image is increasing in positive value and meaning so that modern churches have used visual images such as films, pictures, and dramas as aids for preaching or worship. This contemporary circumstance calls for the pursuit and development of the positive theology of the image in Protestantism for our contemporary Protestant churches. However, the majority of Protestant churches and minsters seems to assume that there is only a negative perspective toward visual images in the theology of the Reformation. This assumption presents an obstacle to pursuing and finding a positive theology of images in order to use visual images for devotion and worship in Protestantism. With this context as a foundation, the objective of this study is to find a positive perspective of visual images in Protestant theologies. To this end, this article addresses the abuse of images in the late medieval period and then analyses three reformers’ perspective of image: Andreas Bodenstein von Karlstadt, Martin Luther, and John Calvin. The first was the official initiator of the iconoclasm in the sixteenth–century Reformation and the latter two reformers have still exerted influence on our contemporary Protestant churches. This is the reason why I choose these three among the sixteenth–century reformers.

혈우병 환자에 동반된 자발성 후복막강 출혈

김광일,김동호,우상민,이석주,김홍성,조인성,윤환중,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

Spontaneous retroperitoneal hemorrhage due to hemophilia A with impaired coagulopathy is very rare. Spontaneous retroperitoneal hemorrhage has been recorded as having originated from many retroperitoneal organs and blood vessels, and it may be due to local and/or systemic factors. In the majority of the patients, kidney and adrenal gland were the major site of hemorrhage. The systemic causes of spontaneous retroperitoneal hemorrhage are anticoagulation therapy and chronic hemodialysis. During the course of these treatments, hemorrhagic complications may occur at many site, including the retroperitoneal space. Blood dyscrasias including leukemia, polycythemia, sickle cell trait and hemophilia have been reported associated with spontaneous retroperitoneal hemorrhage. We report a case of spontaneous retroperitoneal hemorrhage occurred in a gemophilia A patient with brief review of literature