나의 감사 일주일 : 하나님께 순종, 교회와 성도를 섬김

장석종 기독교대한성결교회 활천사 2021 활천 Vol.812 No.7

수소이온농도 변화의 수축물질에 따른 가토신동맥 수축에 미치는 영향과 기전

장석종,김세훈,전병화,박해근,Chang, Seok-Jong,Kim, Se-Hoon,Jeon, Byeong-Hwa,Park, Hae-Kun 대한생리학회 1990 대한생리학회지 Vol.24 No.1

The effects of $H^{+}$ on the arterial contraction and their mechanisms were investigated in the renal artery of a rabbit. The helical strips of isolated renal artery were immersed in the HEPES-buffered or $CO_{2}/HCO_{3}^{-}$-buffered Tyrode's solution. The contractions induced by agonists (norepinephrine, histamine, serotonin and angiotensin II) or high $K^{+}$ were observed with change of extracellular or intracellular $H^{+}$ concentration. The contractions induced by norepinephrine, histamine, serotonin, angiotensin II or high $K^{+}$ in HEPES-buffered Tyrode's solution were inhibited by increase in extracellular $H^{+}$ concentration and potentiated by decrease in extracellular $H^{+}$ concentration. The degrees of these effects were most evident in the contraction induced by serotonin and angiotensin II, moderate in those by histamine and high $K^{+}$, and least in those by norepinephrine. Maximal contraction by norepinephrine, histamine and high $K^{+}$ were not influenced by change in extracellular $H^{+}$ concentration, but influenced in those contration by serotonin and angiotensin II. The attenuated contractions by an acidic pH were not returned to the level of contraction at normal pH (7.4) by elevation of extracellular $Ca{2+}$ concentration. The agonists (norepinephrine, histamine and serotonin)-induced contractions in $Ca{2+}$-free Tyrode's solution were also attenuated by increase in extracellular $H^{+}$ concentration and potentiated by decrease in extracellular $H^{+}$ concentration. Elevation of $Pco_{2}$ in the $CO_{2}/HCO_{3}^{-}$-buffered Tyrode's solution, which increase the intracellular $H^{+}$ concentration, at constant extracellular pH (7.4), increased the contraction by 30 mM $K^{+}$. From the above results, it is suggested that the decrease in contractions by increase in extracellular $H^{+}$ concentration may be resulted from that $H^{+}$ make the receptors less sensitive to agonists and cell membrane hyperpolarize and then inhibit the $Ca{2+}$ influx as well as $Ca{2+}$ release from intracellular $Ca{2+}$ storage site.

돼지 관상동맥에서 고려인삼의 Protopanaxatriol과 Protopanaxadiol의 혈관이완 효과 ( Vasorelaxing Effect by Protopanaxatriol and Protopanaxadiol of Panax ginseng in the Pig Coronary Artery )

장석종,서장수,전병화,남기열,박해근 고려인삼학회 1994 Journal of Ginseng Research Vol.18 No.2

심실근의 수축현상에 미치는 O₂, CO₂ 및 pH의 영향

장석종,박해근 충남대학교 의과대학 지역사회의학연구소 1983 충남의대잡지 Vol.10 No.2

It has been well known that increased hydrogen ion concentration causes the negative inotropic effect on the heart. But in the status of acid base imbalance, metabolic or respiratory, the question of which status has more profound effect on the cardiac muscle contractility remains unsolved. Furthermore, whether such effect is attributable to the change of the intracellular pH or the extracellular change is a matter of controversy. In many studies concerning to the effect of carbon dioxide tension on the cardiac contractility, the effect of excess oxygen has been ignored despite of its significant influence upon the cellular function. The author intended to investigate the effects of the change of carbon dioxide tension, which causes the pH change simultaneously, as well as the effect of excess oxygen on the cardiac ventricular contractility. Also, to prove which change, metabolic or respiratory, has more profound effect and which change, intracellulcr or extracellular, has more crucial effect, the author examined the contractility of the ventricle under two different conditions. They were as follows: a) PCO_2 was varying despite of same magnitude of the change in pH. b) pH was varying despite of the same magnitude of the change in PCO_2 Turtle hearts were used and the Langendorf preparations were made. The perfusate was Tris-buffer solution for turtle, saturated with various gases, such as air, pure oxygen, nitrogen, or different concentrations of CO_2 balanced with oxygen or nitrogen. The tension and maximal dT/dt were recorded with the Physiograph and its accessories. The results were summarized as follows. 1. The excess oxygen enhanced the ventricular contractility. 2. Increased carbon dioxide tension, which decreases the pH simultaneously, reduced the ventricular contractility and that was more pronounced when CO_2 was balanced with nitrogen gas rather than with oxygen gas. 3. The relationships among several physiological parameters were estimated as follows: a) Y=1.01X-0.56 X: percent change of the tension Y: percent change of maximal contration dT/dt b) Z=1.06X-4.56 Z: percent change of maximal relation dT/dt The corelation coefficient in a) is 0.939 and in b) is 0.926, being significant statistically (P<0.005). 4. When the change of pH were same but the changes of PCO_2 were different, the change of ventricular contractility was more profound in the respiratory decrease of pH, that was higher PCO_2, more depressing effect (P<0.005) was manifested, than in the case of metabolic origin (p<0.005). 5. When the changes of PCO_2 were same but the changes of pH were different, the influence of the latter parameter on the contractility was not significant (P<0.1). From the above results it was suggested that the increased PCO_2, which also causes the decrease of pH, has negative inotropic effect and excess oxygen has positive inotropic effect on the ventricular muscle of the turtle. The negative inotropic effect of the lowered pH on the ventricular muscle was revealed to be more profound when it was induced by respiratory distress rather than motabolic and may be affected by change of intracellular pH rather than extracellular pH.

산도가 장관의 운동성에 미치는 영향

장석종,박해근,김광진,임현재 충남대학교 의과대학 지역사회의학연구소 1982 충남의대잡지 Vol.9 No.2

The effects of hydrogen ion concentration changes on the motility as well as patterns of motility to autonomic drugs was investigated in the isolated duodenum and ileum of rabbits. Motility was recorded on a Physiograph with force transducer by means of Magnus method in sodium lactate Ringer's solution at 37℃ The pH of the Ringer's solution used were nornal (pH 7.4), acidic (7.4-5.5), and alkaline(7.4-9.5), titrated by 0.01 N BCI or 0.01 N NaOH solution respectively. Acetylcholine and norepinephrine as autonomic drugs was treated at normal, acidic, and alkaline Ringer's solution. Obtained results may be summarized as follows. 1. Increased hydrogen ion concentration (or decreased pH) inhibited tie motility of duodenum and ileum and that was proportional to increment of hydrogen ion concentration. 2. Decreased hydrogen ion concentration(or increased pH) enhanced the motility of duodenum and ileum and that at was proportional to decrement of h drocen ion concentration. 3. Effect of acetvlcholine on the patterns of motility in duodenum and ileum was not altered by hydrogen ion concentration changes. 4. Effect of norepinephrine on the patterns of motility in duodenum and ileum was not altered by hydrogen ion concentration changes.

Investigation on noise of rotary compressors using fluid-structure interaction

장석종,정한아침,박서룡,이수갑 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.11

Air conditioners consist of heat exchangers, fans, motors and compressors as major components. From the viewpoint of noise, the compressor occupies a very large portion. In this study, rotary compressor which is mainly used in domestic air conditioner was discussed. The noise generated from the rotary compressor can be classified into pressure pulsation of the refrigerant and structural vibration. During the operation of the compressor, the behavior of the refrigerant and the internal structure of the compressor strongly interact with each other. Therefore, an integrated interpretation is required when analyzing from the viewpoint of refrigerant. In this study, the rotary compressor behavior is implemented using the FSI technique and the noise and valve behavior with and without discharge muffler are analyzed.

Furosemide가 개구리 피부를 통한 Sodium의 능동적 이동에 미치는 영향

장석종,박해근 충남대학교 의과대학 지역사회의학연구소 1976 충남의대잡지 Vol.3 No.2

This investigation was undertaken to study the effect of furosemide on sodium transport across the frog skin. In the experiments, freshy abdominal skin of frog were used and SCC and PD were measured by method of Ussing and Zerahn(1951). The results may be summarized as follows ; 1) Furosemide decreased the SCC d PD but increased the resistance in inside medium only. The degree of fall of SCC and PD and rise of resistance were directly proportional to the concentration of furosemide. 2) The SCC and PD were decreased apparently above the 3×10^-4 M/L of furosemide. Especially, the SCC was statistically significant (P<0.01). 3) The maximal changes of SCC, PD and resistance were shown in 18×10^-4 M/L of furosemide. 4) In all of the experimental concentration the changed SCC, PD and resistance were recovered completely with normal Frog-Ringer solution, except in 24×10^-4 M/L of furosemide.

가토 경부 미주신경의 전기 자극에 의한 맥박 및 혈압 변동에 관한 연구 : 특히 좌·우측 미주신경의 차이점을 중심으로 Special Reference to Difference between Right and Left Vagus

장석종 충남대학교 의과대학 지역사회의학연구소 1977 충남의대잡지 Vol.4 No.2

This investigation was undertaken to differentiate the vagal effects between right and left vagus on heart rate and blood pressure in rabbit. Electrical stimulation was applied on the vagi in cervical region to peripheral and cranial end before or after cutting the vagi. The heart rate and blood pressure change were recorded and analized. The results may be summarized as follows: 1. Right vagal efferent fiber stimulation inhibited the cardiac function more significantly than the left. 2. In the vagal afferent fiber stimulation, there were no difference between the right and left on blood pressure and heart rate. In the above results, right vagal efferent fiber to the heart may be dominant than left vagus in rabbit.

자연치유력 회복을 위한 에너지테라피가 중년기 성인의 기독교 영성 생활 증진에 미치는 효과: 기도 생활 및 대인관계를 중심으로

장석종 한세대학교 영산신학연구소 2022 영산신학저널 Vol.- No.60

The purpose of this study is to confirm how energy therapy, which regulates the energy flow of the human body, can improve the spiritual life of middle-aged Christians. To this end, from January 7 to March 11, 2022, a hands-on study was conducted on 30 people applying energy therapy once a week. The collected data were analyzed for frequency analysis, correlation analysis, and mean differences through the corresponding sample t-test using the SPSS 26 statistical program. In order to confirm the effect of promoting spiritual life by energy therapy, prayer life, interpersonal relationships, and subjective health awareness items were analyzed as questionnaires. As a result of the analysis, prayer life and interpersonal relationship (communication, friendliness, openness) were significantly improved through energy therapy, and subjective health awareness (sleep, excretion, and digestion) were also improved. These results reveal that the physical health and spiritual life of the human are related to each other, and can be seen as a result of enhancing the natural healing power of the human body by facilitating the flow of blocked and disproportionate energy in the human body through energy therapy. The significance of this study is that it suggested a way to improve the spiritual life of Christians exposed to middle-age stresses through control of the human body’s physical health. The study confirms that it is important to smooth the overall energy flow of the body before relying on specific foods or drugs for physical health. In this respect, this study is considered to be basic data for those who want to promote preventive medicine and Christian spiritual life. 본 연구의 목적은 인체의 에너지(氣) 흐름을 조절하는 에너지테라피가 중년기 기독교인의 영성생활 증진에 어떤 효과가 있는지를 확인하는 것에 있다. 이를 위해 2022년 1월 7일에서 3월 11일까지 30명을 대상으로 1주일에 1회 에너지테라피를 적용한 실습 연구를 진행하였다. 수집된 자료는 SPSS 26 통계프로그램을 사용하여 빈도분석, 상관분석 및 대응 표본 t-test를 통한 평균 차이 등을분석하였다. 에너지테라피에 의한 영성생활 증진 효과를 확인하기 위하여 기도생활, 대인관계, 주관적건강 자각 항목에 대해 설문지로 분석하였다. 분석 결과, 에너지테라피 실시를 통해 기도생활, 대인관계(의사소통, 친근감, 개방성) 정도가 유의하게 향상되었고, 주관적건강 자각(수면, 배설, 소화) 역시 향상되었다. 이러한 결과는 인체의 신체적 건강상태와 영성 생활이 서로 연관되어 있음을 밝히는 결과이며, 에너지테라피를 통해 인체에서 막히고 불균형적인 에너지(기혈)의 흐름을 원활하게 하여 인체의 자연치유력을 높인 결과로 볼 수 있다. 본 연구의 의의는 인체의 신체적 건강 조절을 통해 중년기 스트레스에 노출된 기독교인들의 영성생활을 증진 시키는 방안을 제시하였다는 점이다. 또한신체적 건강을 위해 특정한 음식이나 약에 의존하기 이전에 몸의 전체적 에너지 흐름을 원활하게 하는 것이 중요함을 제시하였다는 의의가 있다. 이런 측면에서 본 연구는 예방의학적 측면과 기독교 영성생활을 증진하려는 이들을 위한 기초 자료가 된다고 본다.

기독교 자연치유로서 오감 멀티테라피에 대한 연구

장석종 한세대학교 영산신학연구소 2017 영산신학저널 Vol.0 No.39

Korean churches have experienced “supernatural healing” and “inner healing” ministries. The former refers to healing through prayers, whereas the latter refers to healing within unconscious inner wounds by the Holy Spirit. Recently, healing through harnessing the nature, natural healing, has shed a new light on incurable and chronic illnesses. Western medicine has shown its weaknesses and the public started to take a interest in natural healing. Under these circumstances, the author examined the possibility of Christian natural healing based on the biblical outlook. Could Christian natural healing settle down as a part of the church’s healing ministry? Could Jesus Christ take His lordship in the area of natural healing? To answer above questions, this article studies a couple of potentialities within natural healing for the following reasons. First, the Bible itself acknowledges natural healing as well as the supernatural healing. Second, recent natural healing studies suggest “five-sense multi-therapy”. The five-sense therapy has theorized that humans can experience great healing through accepting healing forces in the nature. The Creator granted the power of recovery to his creations. Energy for healing exist in the nature. Therefore, embracing it through five senses could lead to healing. The five-sense multi-therapy is categorized into distinct areas with each practice focusing on a particular sensory organ: “colortherapy”, “aromatherapy”, “soundtherapy”, “foodtherapy”, and “meridiantherapy.” On the basis of research, the author suggests that contemporary church could carry healing ministry through Christian natural healing in the form of five-sense multi-therapy. Furthermore, the author expects his study to legitimize the biblical validity of natural healing ministry to those who practice natural healing with uncertain foundation. 한국교회는 “초자연적 치유”와 “내적 치유” 사역을 경험했다. 초자연적 치유는 기도로 치유하는 것이고, 내적 치유는 성령의 역사로 내면의 무의식적 상처를 치유하는 것이다. 요즘에는 “자연을 이용하여 치유”하는 “자연치유”가 새롭게 조명을 받고 있다. 서구 의학이 암을 비롯한 불치병과 만성질환에 무기력한 면을 드러내자, 사람들이 점차 자연치유에 관심을 돌리게 된 것 같다. 이런 상황에서 필자는 자연치유 사역을 하는 그리스도인으로서 “자연치유가 새롭게 각광을 받고 있는 시대에 성경의 세계관에 기초하여 기독교 자연치유의 가능성을 열어갈 수 있을까?” 하는 질문을 던져 보았다. 과연 기독교 자연치유가 교회 치유 사역의 한 영역으로서 자리 잡을 수 있을까? 예수 그리스도가 자연치유 영역에서도 주님이 되실 수 있을까? 이 질문에 대해 이 논문은 다음과 같은 이유로 기독교 자연치유가 가능하다고 보았다. 첫째, 성경이 초자연적 치유뿐만 아니라 자연치유를 긍정하고 있다. 둘째, 하나님의 창조에 토대를 둔 오감 멀티테라피를 제안한다. 오감 멀티테라피는 인간이 오감을 사용하여 하나님께서 창조하신 자연에 있는 치유력을 수용하면 치유를 경험할 수 있다는 이론이다. 오감 멀티테라피론은 하나님이 인간에게 자연치유력을 주셨고 자연 안에 이미 하나님이 주신 치유의 재료와 에너지가 있으니 오감을 통해 이를 수용하면 치유가 일어난다고 설명한다. 오감 멀티테라피는 구체적으로 눈의 시각을 이용한 “칼라테라피”, 코의 후각을 이용한 “아로마테라피”, 귀의 청각을이용한 “사운드테라피”, 입의 미각을 이용한 “푸드테라피”, 피부의 촉각을 이용한“메리디안(경락)테라피”를 말한다. 이런 연구에 근거하여 필자는 21세기 교회는 성경이 긍정하는 자연치유를 오감 멀티테라피라는 기독교 자연치유 사역으로 실행할 수 있다고 제안하고자 한다. 이논문이 지금까지 신학적으로 모호한 기반 위에서 자연치유 사역을 감당해 온 그리스도인들에게 성경적, 신학적 정당성을 부여해 주기를 기대한다.