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          • Copper-T 피임효과에 관한 연구

            예민해 충남대학교 의과대학 지역사회의학연구소 1974 충남의대잡지 Vol.1 No.1

            This paper showed that studied on the effect of Copper-T contraceptive about 528 rural women who resided in five Myun of Youngchun country for one year from April, 1972 to March, 1973. The results obtained were as follows: 1) The effect of Copper-T contraceptive was 99.7% it was better than other contraceptives except oral pill. 2) Among the women inserted Copper-T 200, the expulsion was 5.9% and the removal was 23.%. The total of termination was more or less lower than Lippes' loop but higher than Kim's result. 3) The side effect was 45.2%, it was similar to Lippes' loop but higher than Kim's result and U.S.A. 4) The continuation rate was 79.4% within six months after insertion and 71.3%, 10 months.

          • 소아에서 수술과 마취가 혈당치 및 심혈관계에 미치는 영향

            최세진,김철호,안미정,김상수 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

            The author observed pulse rate, blood pressure and blood glucose change in vari ous conditions of enflurane-nitrous oxide-Oxygen general anesthesia i. e. before anesthesia, after intubation and operation in 25 anesthetic cases of children aging from 4 years old to 10 years old at department of anesthesia of C. N. U. H. The following results were obtained. 1. It revealed increased pulse rate after intubation and operation than before anesthesia.. 2. It revealed increased blood pressure after intubation than before anesthesia. 3. It didn't reveal significantly increased blood glucose after intubation and operation than before anesthesia

          • 보행속도에 따른 운동형상학적 특성

            김봉옥,윤승호,모정욱,김병식 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

            Kinematic characteristics at different speeds of walking are important to understand the basic mechanisms of locomotion. Fourteen men with no history of neuromusculoskeletal disorder were studied with three dimensional motion analysis system during walking with 5 different speeds (57.11-99.09m/min). Time parameters, distance parameters, and kinematic analysis of ankles, knees, hips, and pelvis on sagittal, coronal, and transverse planes were compared with each other on different walking speeds. It is found that increasing walking speed 1. increased stride length and stride length raio, but decreased the step length and step length ratio. 2. increased the angle of ankle, knee & hip joint on sagittal plane during early and late stance period, due to the greater forces at heel-strike and toe-off. 3. did not change the kinematic characteristics of ankle, knee & hip joints on 3 planes during the swing phase. The result of this study can be usefully utilized as the basic data to design and evaluate prosthetic devices, and to detect abnormal gait performances.

          • 3'-Methyl-4-dimethylaminoazobenzene이 백서의 정상 및 재생간의 EGF Receptor 변동에 미치는 영향

            홍장희,허강민,석정호,이재흔 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

            To study the changes of EGF receptors in the rat liver regeneration and hepatic carcinogenesis, ^125I-EGF binding sites were measured in the regenerated liver cell membrane after partial hepatectomy of normal rat and 3-methyl-4-dimethylaminoazobenzene treated rat. 1. EGF binding sites (Bmax) in the normal rat liver cell membrane were 553.8fmole/mg protein and were markedly decreased at the 1st day after partial hepatectomy. These sites were increased at the 3rd day(Bmax-161.0fmole/mg protein) and were 29% of the normal liver EGF binding sites. 2. EGF binding sites (Bmax) in the normal cell membrane of the 3-methyl-4-dimethylaminoazobenzene-treated rat, were 72.8fmole/mg protein and were significantly less than those in the normal rat live cell membrane. At the 1st day after partial hepatectomy, EGF binding sites were markedly decreased and increased at the 3rd day (Bmax=155.8fmole/mg protein). 3. Kd values in EGF receptor binding were not much altered in both liver cell membranes of the normal rat and the 3-methyl-4-dimethylaminoazobenzene treated rat. From these result, it is suggested that decreased EGF binding sites in the liver cell membrane of regenerating rat liver and 3-methyl-4-dimethylaminoazobenzene treated rat may be due to the alteration of EGF receptor number.

          • 침전극의 종류에 따른 운동단위활동전위의 정량적 비교

            윤승호,손민균 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

            Motor unit action potentials(MUAPs) were recorded from the biceps brachii and first dorsal interosseous muscles to identify the electrode effect on the properties of MUAPs between concentric and monopolar electrode in 25 healthy adults. The parameters of MUAPs such as amplitude, area, spike amplitude and number of phases recorded with monopolar electrode were larger than those recorded with concentric needle, but in contrast there were no significant difference on mean MUAP duration between two electrode types in both muscles. The most common shape of MUAPs were triphasic in both electrode recordings and the incidence of polyphasic and polyturn MUAPs were higher in monolar recordings than concentric. The rise time was inverse relationship with the amplitude, and number of phases and turns. And in general there were significant correlation between the duration, the amplitude, the area, the spike amplitude and area, the number of phases and turns. Therefor different reference values must be used in analyzing the MUAP recorded by concentric and monopolar electrodes.

          • 보행환경이 보행에 미치는 영향

            조강희,유재욱,김봉옥,윤승호 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

            Fall-related accidents account for more than 800,000 injuries and 13,000 fatalities a year in North Americain. And also it is estimated that one-third of all persons 60 years old and older suffer falls each year. The Balance and posture are affected by vision, vestibular system and somatosensory system(proprioception). Three influences related to the older population's risk of falling are normal aging progress, pathology that increases with age and environmental conditions. In this study, to understand the effect of various environmental conditions on kinetic characteristics of initiation of gait and standing posture, vertical ground reaction forces(VGRF), center of pressurc(COP), postural analysis and psychologic index were evaluated in 20 men with no history of neuromusculoskeletal abnormality. The results are 1) VGRF according to various environmental conditions are not significant change. 2) Temporal analysis of IOG according to carpet and wood floor are significantly slowed in wooden floor. 3) Temporal analysis of IOG with or without shoes are not significnat change. 4) The effects of illumination to balance increased maximal oscillation by decreased of illumination

          • 인삼이 말초신경 장애성 통증에 미치는 영향과 그 기전에 관한 연구

            홍기완,김광진 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

            The aim of the present study was to investigate the antinociceptive effects of ginseng extracts on neuropathic pain evoked by peripheral nerve injury in rats, according to the method of Bennett and Xie. Chronic constrictive nerve injury to sciatic evoked markedly allodynia, which was determined by withdrawal time and ratio to the innocuous mechanical, chemical and cold stimuli (5oC) applied to the hind paw. Total saponons of ginseng extract(100mg/kg) inhibited allodynia to the stimuli applied but higher dose of saponins had no effect. Among the saponin extract, protopanaxadiol saponins(PT) was found to be the effective component for the antinociceptive action of ginseng extracts on neuropathic pain. On the other hand the prototopanaxatriol saponins (PD) had no effect on neuropathic pain. MK-801(1.6mg/kg) and IA-966(0.1mM/kg) enhanced the antinociceptive effect of PT on chemical and cold allodynia. MK-801 and HA-966 enhanced, transiently, the effect of PT on chemical and cold allodynia. Apomorphine(4mg/kg) inhibited all the mechanical, chemical, and cold allodynias in the neuropathic animal that was reversed by the first day of PT administration, but returned to the inhibited state on the second day of PT administration. Serotonin(60mg/kg) enhanced transiently the antinociceptive effect of PT on allodynia to mechanical and chemical stimuli, but showed prolonged effect on the allodynia to cold stimuli. PT enhanced transiently the antinociceptive effects of the TEA(10mM) on allodynia to mechanical and chemical stimuli, but the enhanced effect on cold allodynia was maintained. From these results it is concluded that total saponin extracts of ginseng has antinociceptive effects on the allodynia to mechanical, chemical and cold stimuli in the neuropathic pain animal, and among the ginseng extract PT is the effective component, and that the mechanism of the antinociceptive effects of PT is not simple.

          • 만성 부비동염 환자에서 비기류에 대한 민감도의 변화

            나기상,이석호,임동우,김병국,박찬일 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.2

            Nasal patency may be considered to have two aspects: the resistance to airflow and the sensation of airflow. Although the sensation of nasal airflow has received little attention from clinicians, it is likely that it is of great importance in clinical practice. However, there are no study that assess the sensation of nasal airflow in patients complaining of nasal obstruction. The aim of this study is to assess the airflow sensitivity of the nose in patients with chronic paranasal sinusitis. To assess the airflow sensitivity, we designed an apparatus delivering a pulsing jet of air at varying velocities. We measured threshold velocities at six different sites of each nasal cavity in fifteen patients and compared with the values in normal subjects. All patients had bilateral chronic sinusitis with polyp. The threshold velocities at all but site 5 were higher in sinusitis patients than in normal subjects. The difference at site 1, 3, 4 and 6 was statistically significant. Since a high threshold velocity indicates low sensitivity, our results suggest that airflow sensitivity is lowered in patients with chronic sinusitis. Disturbance of airflow sensation may contribute to the sensation of nasal obstruction in patients with chronic paranasal sinusitis.

          • 반사광을 이용한 산소포화도 측정장치의 개발에 관한 연구

            임현수 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

            The oxygen saturation of blood can be measured by the difference absorption in optical spectra of Hb and HbO_2, as the well known previous study^1). In this study we developed the noninvasive oxygen measurement device for clinic trial using two kind of LED which produce a peak spectral emission at a wavelength of 660nm, and 940nm. To evaluate the clinical application of the oxygen measurement device, we performed first finger study to measure the oxygen saturation changes in response to physiological changes within biological tissue. The results showed that oxygen saturation of blood in biological tissue can be monitored from the separation arrangement light source and detector.

          • 家兎血壓反應에 미치는 Adenosine Diphosphoribose의 影響

            李神雄,白汶基 충남대학교 의과대학 지역사회의학연구소 1974 충남의대잡지 Vol.1 No.1

            Effect of adenosine diphosphoribose(ADPR), one of metabolites of nicotinamide adenine dinucleotide, on the rabbit blood pressure was investigated. ADPR(10㎍/kg) induced transient fall of the blood pressure. Increasing the doses, hypotensive response to ADPR was also increased. This vasodepressor effect of ADPR was not affected by hexamethonium, atropine, propranolol, methysergide and promethazine pretreatment.

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