서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

알코올 의존 환자의 Tryptophan Hydroxylase 유전자 다형성

홍주봉,이상익,신철진,김헌,지경환,정인원 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

연구목적 : 알코올 의존 환자에서 세로토닌 합성 조절 효소인 tryptophan hydroxylase(TPH) 유전자 다형성 빈도를 정상 대조군과 비교함으로써 알코올 의존의 유전적 요인을 추적하고, 임상변인과 이 유전자 다형성과의 관련성을 알아보고자 하였다. 방 법 : DSM-IV진단기준에 부합되는 알코올 의존 환자 100명과 정상 대조군 100명을 대상으로 TPH유전자 다형성을 증합효소 연쇄반응과 제한효소 처리법을 이용하여 동정하였다. 여기서 분리된 대립 유전자와 유전자형에 따른 빈도의 차이를 서로 비교하였으며, 알코올 의존 환자군의 여러 임상 변인에 따른 차이를 비교하였다. 결 과 : 알코올 의존 환자군과 대조군 간에 TPH의 A216C 유전자형 및 대립유전자 빈도에서의 통계적으로 유의한 차이는 관찰되지 않았으나, 조기 발병한 환자의 경우는 유전자형의 빈도가 AA,AC,CC형이 0.57, 0.39, 0.04, 후기 발병한 환자의 경우 0.34, 0.45, -.21로, 조기 발병한 환자군에서 대조군과 비교하여 통계적으로 유의하게 A 대립 유전자의 빈도가 높은 것이 관찰되었다.(by chi-square test, p<0.05). 결 론 : 이는 조기 발병형 알코올 의존의 경우 TPH유전자 다형성과 관련이 있으며, 일부 알코올 의존 환자에서 유전적으로 세로토닌계의 이상이 있다는 사실을 시사한다. Objectives : This study was performed to explore the association of tryptophan hydroxylase (TPH) gene with diagnosis of alcohol dependence and/or clinical characteristics such as age of onset, family history, and severity of symptoms in Korean alcoholics. Methods : The genotype and allele frequencies of TPH in 100 male hospitalized patients who met DSM-IV criteria for alcohol dependence were investigated using polymerase chain reaction and restriction fragment length plymorphism and were compared with 100 age-matched healthy male control subjects. And the associations between gene polymorphisms and clinical characteristics in alcoholic patients were explored. Results : The distributions of TPH genotype and allele in alcohol dependent patients were not different from control subjects. However, the frequencies of TPH genotype in early-onset alcoholic patients, which were 0.57, 0.39, and 0.04(AA, AC and CC, respectively), were significantly different from those of late-onset alcoholics(0.34, 0.45, and 0.21, respectively). "A" allele was found more frequent in early-onset alcoholics. Conclusion : The result suggests that TPH gene polymorphism is associated with early-onset alcioholic patients possibly related with inherited abnormalities of serotonin system.

폐결핵 환자의 우울 상태

홍정표,최선희,조만종,이성주,박종,김기순,김양옥 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.1

The main purpose of this study is to identify and evaluate the depressive states for the patients with chronic pulmonary tuberculosis. A questionnaire(Self-rating Depression Scale, SDS) survey was performed toward 57 pulmonary tuberculosis patients with initial treatment who started chemotherapy and 53 pulmonary tuberculosis patients with retreatment, admitted to one tuberculosis-centered hospital and two general hospital. Fifty three healthy persons as control group were investigated with the same questionnaire for comparison. The survey was performed from July to August 1996. The results are as follws : 1. The patients had significantly high scores in the depression than control and the patient with retreatment showed significantly high scores in the depression than the patient with initia1treatment(P<0.01). 2. The depressive levels of the patients were associated with duration of admission and the expectancy of recovery (P<0.05). 3. The percentage of the subjects with 40 or more scores tentatively classifiable as psychologically depressed was 67.1% of the total subjects, 48.4% of the control groups, 75.0% of the patient with initial treatment and 84.1% of the patient with retreatment. Because patient with pulmonary tuberculosis with initial treatment showed higher depression scores than normal persons, and patients with retreatment due to failure of initial treatment showed higher depression scores than initial treatment, it is necessary to give attention to depression of the patients during treatment of pulmonary tuberculosis.

대학 전산 정책의 방향설정 및 추진계획에 관한 연구

홍상은,이병수,조충호,이상정,주경수,안종근,황순기 순천향대학교 1994 논문집 Vol.17 No.1

It has been rapidly given to the importance of the embodiment of the efficient computer systems in university education. Since the recent trend of the adoption of the openess policy in university education systems significantly affects on the realization of the embodiment of the efficient computer systems which is very essential to promote the international competition in many areas of university education. So it is greatly needed that our Soonchunhyang university must have the following principles for the embodiment of the efficient computer systems. (1) It is required that the appropriate computer education and the good quality of research environment must be given. (2) The establishment of the synthetic computer network system for efficient the university administrations is needed. (3) It is needed to establish the computer system for the consideration of the future performance. (4) It is also needed to improve the organization and the administration systems of the university computer center. (5) It is required on the establishment of the local area network(LAN) systems in the Soonchunhyang university, and the LAN must be connected to other outer national and international computer systems. And we propose the following requirement for the establishment of the convienent computer systems in our university and we have been greatly though about the significant change of the environment in university computer system. [1] The subject of the basic computer must become as the required subject for the all students in the curriulum. [2] The new computer systems both in hardware and software must be introduced. [3] It is needed to the change of the present name of the university computer center into the university information and computer center. And its organizations must be furthur developed [4] The training center for the university emploee is also needed. [5] The establishment of the database systems for the automtion of the university administation is needed. [6] It is strongly required on the establishment of the local area network system in the Soonchunhang university to connect the Bitnet and the Internet through the Hankook communication. [7] The computerization for the central library is needed. The indepent local area network system for the library is also needed to establish the own database system. Finally we hope that the LAN will be connected to the national wide library computer system.

컴퓨터그래픽을 이용한 실내디자인 조명효과의 예측을 위한 연구실험 : 음영처리기법의 비교를 중심으로 Focused on the Comparison of Shading Algorithm

홍승대,신경주 漢陽大學校 韓國生活科學硏究所 2003 韓國 生活 科學 硏究 Vol.- No.21

In Interior design, light is the most important factor in deciding color, texture and illumination level which are the basic factors of spatial design. To apply computer graphic technologies on prediction of illuminating effect, it is important to understand and analyse the basic properties of the illumination models that are local illumination model and global illumination model. The illumination models in computer graphics express the factors which determine the surface color, texture and light distribution through the reflection. The purpose of this study is to propose the best way of shading algorithm in interior space provided by the computer, based on the experimental analysis that 5 shading methods are applied to the interior space. The results of this study were as followed. 1) Local illumination models that are lambert shading, Ground shading and phong shading are not suitable to the prediction of interior illumination effect. 2) Raytracing that is global illumination model could be adopted to interior illumination effects. Ray tracing is a very versatile algorithm because of the large range of lighting effects it can model. 3) Neither radiality nor ray tracing offers a complete solution for simulating all interior illumination effects. 4) Radiality excels at rendering diffuse-to-diffuse inter-reflections and ray tracing excels at rendering specular reflections. By merging both shading techniques, that offers the best of both. Using computer technologies to simulate lighting in preliminary design stage which will provide information for designers and occupants to determine the effect of using artificial light sources at each stage of their design process. Further study in illumination analysis, prediction of illumination effect, and lighting calculation is required as computer media expands. Professor of Ansan College of Technology, Dept. of Interior Design Professor of Hanyang University, Dept. of Interior Design

두 dystopia에 나타난 대조적 dilemma Lord of the Flies와 A Clockwork Orange를 중심으로

홍성주 漢陽大學校 人文科學大學 1990 人文論叢 Vol.20 No.-

William Golding's Lord of the Flies and Anthony Burgess' A Clockwork Orange are the anti-Utopian novels. They have many things in common-the theme of dystopia, the form of fable, and the element of science fiction. In spite of these similarities two authors present quite different levels of intrpretation about the nature of evil in the dark world of dystopia. For Golding without civilized restraints life becomes nasty and brutish because of the evilic part of man's mature. The only alternative to civilization, therefor, is savagery and moral chaose. It seems clear that Lord of the Flies should be read as a moral novel embodying a conception of human depravity. While moral choice by reason and rule is Golding's main concern, its significane is purpolsely ignored by Burgess. He rathe tries to deal with the theme of man's free will in opposition to a clockwork orange society, where totalitarian social institutions cause a loss of a human being's will and his soul. The most devilish thing, therefore, is the inhuman social institution, which tries to condition the humans. He evasively suggests that the chaotic violence is inevitable and that it can be justified to some extent. In Lord of the Flies Ralph, as the leader of the boys, tries to establish and preserve an orderly, rational society. He provides for good and shelter, and suggests to light a signal fire. But this rational society begins to break down almost at once by the hunters led by Jack, who create their own primitive, savagery, orgiastic tribal society. They accidently kill Simon, the symbol of the supernatural world, and also kill Piggy violently, a scientific-minded raationalist. When Ralph, at the end of the novel, weeps for "the end of innocence," "the darkness of man's heart," the reader assumes that "darkness" here refers to the dark of evil side of man's nature. Alex, the narrator of A Clockwork Orange, is a fifteen-year-old boy who enjoys violent crimes-muggings, rapes, burglaries and so on. He tells his story in a teenage slang, Nadsat, a language invented by the author from Russian and from English cockney slang. But his violence is a desperate gesture of display of free will. He actively resists the sterile, mechanical life under a totalitarian society, where man's surrender of freedom is inevitable. Caught by the police, he becomes the object of an experiment of the Ludovico technique. As a result, he associates sickness with violence and reduces to automation. But his natural reflex of elation in the face of violence is revived by that technique at the end of the novel. Lord of the Flies and A Clockwork Orange present horrible visions of man's mature and of his life, and we are left in a mad, lost, loveless, brutal, sterile world. The reader gloomily sees acceptance of the violence as an innate part of human nature, for both writers imply that we are all violent by nature. In addition, the unanswerable paradoxes and dilemmas still remain: Golding is silent about man's salvation and Burgess avoids the answer about the question of responsibility for our moral choice.

회귀분석(regression analysis)을 이용한 개인별 혈중알콜농도의 감소율 계산

홍성욱,권미아,최혜진,박용훈,인상환,김동우,정주연,우상희,박혜성 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

성인 남성이 선호하는 외투 디자인과 색채에 관한 연구 : 20ㆍ30대를 중심으로

홍성주,김보연,류숙희 계명대학교 생활과학연구소 2001 科學論集 Vol.27 No.-

The purpose of this study is to investigate that men in their 20's and 30's prefer what kind of styles and colors in overcoats. To achieve this purpose, this study was carried out by suggesting the overcoats of 7 styles and 24 colors to 546 men in their 20's and 30's. We analyzed and compared their preferred styles and colors in overcoats, by examining the individual factors such as age, marriage status, personality and education. This study shows the following results. Men in both their 20's and 30's liked the classic styles like style B and neutral colors most. The extroversive and single men in their 20's preferred the casual and polished styles in contrast to others. On the other hand, the introversive and married men in their 30's preferred the classic and formal styles. Skin color has nothing to do with preference of styles.