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홍상은,김옥희,홍하은,김세준,윤국로 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1
Hemorrhage from fatal internal injuries are a major cause of mortality. In particular, massive hemorrhage is lead to serious tissue hypoperfusion and hypoxia. Gelatin is a water-soluble natural polymer derived from collagen. Also, which is biocompatible, biodegradable and non-immunogenic. Currently, in some cases, report that a sprayable polymer materials can be effective at control bleeding from soft tissue such as liver or lung, etc. Using this concept, our research focuses on polymeric sprayable foams based on amphiphilic gelatin. In this study, we tested the amphiphilic gelatin based hemostatic foam for its effect to massive bleeding from liver trauma model in rats. The physicochemical properties and hemostasis effects were confirmed by FE-SEM (Field- Emission Scanning Electron Microscope), TGA (Thermogravimetric Analysis), FT-IR (Fourier Transform Infrared Spectroscopy) and immobilization of blood by gelatin foam test.
Effect of a Caregiver’s Education Program on Stroke Rehabilitation
홍상은,김창환,김이진,좌경림,김태현,김상근,한희준,이의창,정한영 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.1
Objective To evaluate effects of caregiver’s education program on their satisfaction, as well as patient functional recovery, performed in addition to daily conventional rehabilitation treatment.Methods Three hundred eleven subjects diagnosed with first-onset stroke and transferred to the Department of Physical Medicine and Rehabilitation of Inha University Hospital were surveyed. In 2015, caregivers attended an education program for acute and subacute stroke patients. Patients who received an additional rehabilitation therapy were assigned to the experimental group (n=81), whereas the control group (n=100) consisted of transfer cases in 2014 with only conventional treatment. The experimental group was classified by severity using the Korean version of the National Institutes of Health Stroke Scale (K-NIHSS), which was administered to all 181 subjects, in addition to, the Korean version of the Mini Mental Status Examination (K-MMSE), a Modified Barthel Index (K-MBI), and the Berg Balance Scale (K-BBS). Caregiver satisfaction and burden before and after education programs were assessed using the Canadian Occupational Performance Measure (COPM), as well as family burden and caregiver burnout scales.Results No significant intergroup difference was observed between initial K-NIHSS, K-MMSE, K-BBS, K-MBI scores, and times from admission to transfer. Those with moderate or severe strokes under the experimental condition showed a more significant improvement than the control group as determined by the K-NIHSS and K-BBS, as well as tendential K-MMSE and K-MBI score increases. Satisfaction was significantly greater for family members and formal caregivers of patients with strokes of moderate severity in the experimental group.Conclusion The caregiver’s education program for stroke subjects had a positive outcome on patients’ functional improvement and caregiver satisfaction. The authors believe that the additional rehabilitation therapy with the education program aids patients to achieve functional improvements for an optimal return to social life.
홍상은,김옥희,홍하은,김세준,윤국로 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0
Chemotherapy is one of the significant approach for in vivo disease includes cancer treatment but has important challenges, such as cancer cell resistance and various side effect to normal tissue. Here, we have designed and synthesized an effective liver disease treatment agent based on monodisperse ceria-zirconia nanoparticles, which are loaded with drug (which was a typically drug for hepatocellular carcinoma (HCC)) and modified with binding to the hepatocarcinoma A54 peptide (sequence AGKGTPSLETTP) and poly(ethylene glycol) on their surface (S-A54/P-CeZr). The physicochemical properties were confirmed by FE-TEM (Field-emission Transmission Electron Microscope), EDS (Energy-Dispersive X-ray Spectroscopy), DLS(Dynamic Light Scattering), TGA(Thermogravimetric Analysis), 1H-NMR(1H Nuclear Magnetic Resonance) analyses.
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홍상은 순천향대학교 부설 산업기술연구소 1995 순천향 산업기술연구소논문집 Vol.1 No.2
This paper deals with the formulation and its computational algorithm for the look-ahead load dispatch problem of thermal units considering ramp rate and spinning reserve constraints. In the look-ahead load dispatch problem, it is assumed that load prediction is available over the entire dispatching period and the predicted load is specified at uniform discrete time intervals (for example, of 5-15 minutes), then generation from n-dispatchable units is allocated so that operating constraints are satisfied and the production costs are minimized. In the present paper, the look-ahead load dispatch problem is formulated as a multiple time-stage decision process by using a equal lambda method and a linearized power system model. The multi-stage approach allows the inclusion of time-dependent constraints, such as generating unit response rates and spinning reserve over the entire disparching period. When coupled with a short-term load predictor, "look-ahead" capability is provided by the dynamic economic dispatch that coordinates predicted load changes with the rate-of-responese capability of generation units. Numerical examples in a test system are included to demonstrate the effectiveness of the approach which is shown to have feasibility for real power system planning and operation.