Flexural Responses of Prestressed Hybrid Wide Flange Composite Girders

Sun?Jin Han,Deuck Hang Lee,Jae?Yuel Oh,Seung?Ho Choi,Kang Su Kim 한국콘크리트학회 2018 International Journal of Concrete Structures and M Vol.12 No.5

In this study, prestressed hybrid wide flange (PHWF) composite girders were proposed, and full-scale flexural tests were conducted to evaluate their structural performances. This new proposed girder system was developed and designed to effectively resist external loads considering the actual construction sequences. Two specimens with and without shear connectors were fabricated and tested to examine the effect of the shear connectors for achieving the fully-composite behaviors between a cast-in-place (CIP) concrete and the prefabricated prestressed steel–concrete composite girder. The test results showed that sufficient flexural strengths and deformation capacities can be obtained in both types of PHWF composite girders with and without shear connectors. To reflect the actual construction stages of the proposed PHWF composite girder, nonlinear flexural analyses were proposed considering the prestress effect and segmental effect before and after composite with the CIP concrete, respectively. The observed and analysis results of strain behaviors of the PHWF girder specimens were also compared and discussed in detail.

Case Reports : Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas

( Jin Park ),( Yong Sun Cho ),( Ki Hun Song ),( Jong Sun Lee ),( Seok Kweon Yun ),( Han Uk Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.3

Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.

과학영재의 논증 활동에서 나타나는 반박 유형 분석

한혜진 ( Hye Jin Han ),이태훈 ( Tae Hoon Lee ),고현지 ( Hyun Ji Ko ),이선경 ( Sun Kyung Lee ),김은숙 ( Eun Sook Kim ),최승언 ( Seung Urn Choe ),김찬종 ( Chan Jong Kim ) 한국과학교육학회 2012 한국과학교육학회지 Vol.32 No.4

연구에서는 중등 영재 학생들의 논증활동을 반 박(rebuttal)의 측면에서 분석하였다. 반박은 논증 활 동 중에서도 수준 높은 활동이며 과학학습에도 반드시 필요한 요소임에도 불구하고 학생들의 논증활동에 서 부족한 요소인 것으로 지적되어 왔다. 서울지역 영재교육원에 등록한 37명의 8학년 학생들이 태양의 밝기 측정을 주제로 총 4시간 동안 논증활동을 수행하였고 이를 반박의 특성에 따라 분석하였다. 반박의 분류에는 Verheij(2005)의 5가지 반증 유형을 사용 하였다. 연구 결과, 학생들의 담화에서는 5가지 유형 의 반박이 모두 관찰되었다: 자료에 대한 반박(Ⅰ), 주 장에 대한 반박(Ⅱ), 보장에 대한 반박(Ⅲ), 보장의 적용가능성에 대한 반박(Ⅳ), 자료에서 주장으로 가는 과정에 대한 반박(Ⅴ). 학생들이 사용한 반박유형 Ⅰ, Ⅱ, Ⅲ는 상대방의 논증 요소의 과학적 타당성에 대한 반박인 반면, 유형 Ⅳ, Ⅴ는 주장을 제시한 상대방이 고려하지 못한 내용을 제시함으로써 이루어지는 반박이었다. The purpose of this study is to analyze the argumentation of gifted students in the perspective of rebuttal. Rebuttal is a significant indicator of argumentation quality; it is also an essential component for science learning through interaction. However, most previous research point out insufficient use of rebuttal in student`s argumentation. The argumentation of 37 8th grade students, enrolled in institutes for the scientifically gifted in Seoul, are observed and recorded for 4 hours. The argumentation topic is about how to measure the brightness of the sun. Based on Verheij`s (2005) five types of rebuttal patterns, the features of rebuttal are analyzed. It is found that students` argumentation include all of the five rebuttal types: rebuttal of the data, the claim, the warrant, warrant`s applicability, and connection between data and claim. It is also found that these five types can be categorized in two groups. The first group consists of first three types and is characterized by the disagreement with the validity of what has been said. The second group consists of the last two types and is characterized by the suggestion or additional information for missing links in argumentation.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

경피적 전기 신경 자극과 간섭파 치료의 동통 완화 기전에 대한 연구 -날록손 투여가 흰쥐의 꼬리 회피 반사와 뇌 척수액 내 베타 엔돌핀 농도에 미치는 효과-

김진호,한태륜,방문석,김돈규,권범선,임재영 大韓再活醫學會 1997 Annals of Rehabilitation Medicine Vol.21 No.6

혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례

선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

우리나라 일부 여고생과 여대생의 건강 위험 행태 분석

한성현,최민자,이선희,이명선,이혜진 한국모자보건학회 2000 한국모자보건학회지 Vol.4 No.1

좋은 예후를 보인 품행장애 환자에 대한 정신의학적 고찰

진혁희,한선호,한상우 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

The following results were gathered from the extensive research done on the conduct disorder of patients improving and relative conditions. 1. All were good students in elementary school and showed no disobedience. 2. The majority of them had many strong relationships and were very outgoing. 3. Their parents showed much affection toward them in their childhood. Also, they were either the youngest or the oldest in their families consisting of 2 or more. 4. Five out of the 6 patients belonged to upper-middle or just upper class parts of society. 5. Fathers occupied professional occupations and the mothers occupations were domestic housekeeping. 6. They all had parents who were both well educated. 7. The patients attitude toward their parents changed from assertiveness ot obedience and respectfullness. 8. The degree of educational interest by their parents was very high ; 4 out of 6 9. Parents attitudes toward their children changed from traditional to democracy. The family relationship situation was deterioration. Then overtime, the situation inproved dramatically. 10. Parents method of punishing children seems to have changed from the tendency of tough punishment and patients respectful attitude toward their parents has changed from assertive to obedient. 11. There was no history of mental disorders in the family. 12. Most patients had jobs or continued their studies. 13. Conduct disorders occurred in these patients in their late teens. 14. They have never been imprisoned or placed in a mental hospital before.

치근 우식 수복에 사용되는 심미성 수복물의 변연누출에 관한 연구

한진순,임미경 大韓齒科保存學會 1993 Restorative Dentistry & Endodontics Vol.18 No.1

AbstractThe purpose of the study was to evaluate the degree of the marginal leakage of esthetic restorative materials on root caries restoration. 120 cavities were prepared to 90?butt joint on all margins on the crown and root portion, and divided into 4 groups.The four groups of cavity were filled with Amalgam(Dongmuyung Dental Alloy Co., Ltd, KOREA), Silux?3M Co., USA)-Scotch Bond 2?3M Co., USA), Silux?All Bond?BISCO USA), and GC Fuji II?G-C Co., JAPAN) respectively. The apical margin of the preparation was finished to leave a flash of restorative material. The coronal margin of the preparation was finished not to leave a flash of restorative material. All specimens were sectioned longitudinally with Isomet Low speed saw(Buether Ltd, USA). The degree of dye penetration was evaluated as the parameter of marginal leakage under the stereoscope.The results were as follows. 1. At the enamel and dentin/cementum margins, the margin were finished to leave a flash of material showed less marginal leakage than that were finished not to leave a flash of material(P<O.OOl). 2. The enamel margins showed less marginal leakage than the dentin/cementum margins(P< 0.001). 3. There was no significant difference in the degree of the marginal leakage between Silux? Scotch Bond 2?group and Silux?All Bond?group.

타우로우루소데옥시콜린산이 흰쥐의 적출심장에서 허혈 및 재관류 손상에 미치는 영향

한석희,이우용,박진혁,이선미 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

Abstract - In this study, the effects of tauroursodeoxycholic acid (TUDCA) on ischemia/ reperfusion injury were investigated on isolated heart perfusion models. Hearts were perfused with oxygenated Krebs-Henseleit solution (pH 7.4, 37℃) on a Langendorff apparatus. After equilibration, isolated hearts were treated with TUDCA 100 and 200μM or vehicle (0.02% DMSO) for 10 min before the onset of ischemia in single treatment group. In 7 day pretreatment group, TUDCA 50, 100 and 200 mg/kg body weight were given orally for 7days before operation. After global ischemia (30 min), ischemic hearts were reperfused for 30 min. The physiological (i.e. heart rate, left ventricular developed pressure, coronary flow, double product, time to contracture formation) and biochemical (lactate dehydrogenase; LDH) parameters were evaluated. In vehicle-treated group, time to contracture formation was 810 sec during ischemia, LVDP was 34.0 mmHg at the endpoint of reperfusion and LDH activity in total reperfusion effluent was 34.3 U/L. Single treatment with TUDCA did not change the postischemic recovery of cardiac function, LDH and time to contracture compared with ischemic control group. TUDCA pretreatment showed the tendency to decrease LDH release and to increase time to contracture and coronary flow. Our findings suggest that TUDCA does not ameliorate ischemia/reperfusion-induced myocardial damage.