야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

위 (胃) 내시경 (內視鏡) 검사 (檢査) 14 , 389 예에 대한 임상 (臨床) 연구

함준수(Joon Soo Hahm),박경남(Kyung Nam Park),이민호(Min Ho Lee),이성준(Seong Joon Lee),오수철(Soo Chun Oh),한덕호(Duck Ho Han),이종철(Jong Chul Lee),기춘석(Chun Suhk Kee) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.1

N/A Clinical studies were carried out on 14,389 cases who had taken gastrofiberscopic examination, biopsy and X-ray from May, 1969 to May, 1984 in Han-Yang University Hospital. The results obtained were as follows; 1) Of total 14,389 cases, 7,916 were male and 6,473 were female. 55.1%, of the cases were in the 3rd and 4th decade. 2) Of total 14, 389 cases, 13, 615 showed abnormal endoscopic findings. In abnormal cases, male to female ratio was l.2: l.3) The incidence of single organ involved was 84.8% and multiple organs involved was In single organ involved cases, the most common site of disease was stomach and in multiple organ involved cases, the prevalent sites of lesions were stomach and duodenum. 4) The most frequent disease of stomach was gastritis followed by gastric ulcer. In the cases of duodenum, the most common disease was duodenal ulcer and the next was duodenitis. 5) The most prevalent disease was the chronic gastritis, and the frequency of the other upper gastrointestinal diseases was acute gastritis, gastric ulcer, stomach cancer and duodenal ulcer in orders. 6) The most frequent type of chronic gastritis was superficial gastritis. 7) Among the total cases which had been taken blood-typing, the incidence of most upper gastrointestinal diseases was not related to each blood type. But blood group 0 was common in peptic ulcer disease and blood group A in stomach cancer. 8) The clinical symptoms and signs were of no significant aid for the differential diagnosis of the various upper gastrointestinal diseases.

강원도 화천군 수달(Lutra lutra) 서식지의 식생 구조

서형수 ( Hyung Soo Seo ),신영섭 ( Young Seob Shin ),이경은 ( Kyung Eun Lee ),김윤미 ( Yoon Mi Kim ),전미나 ( Mina Jeon ),남택우 ( Taek Woo Nam ),한성용 ( Sung Yong Han ),정연숙 ( Yeonsook Choung ) 한국하천호수학회 2014 생태와 환경 Vol.47 No.special

In order to determine whether vegetation would be one of the factors for the selection of otter home range, vegetation structure and other potential factors were studied in Hwacheon, Korea. Thirteen sites, otter’s activity found and not found, were investigated in North Han River and connected tributary streams of Hwacheon-gun. Three types of vegetation were classified by cluster analysis, which is short grass, tall grass and shrub type. Vegetation zone of each channel is composed of either one type, or mosaic of tall grass and shrub type. Short grass type is common in Lake Paro and upper North Han-river where water level is highly variable throughout a year. Therefore, annual species such as Persicaria nodosa, Fimbristylis dichotomam and Chenopodium ficifolium are the most dominant. Shrub type is common at the downstream sites of Jichon stream and along mainstream of North Han River down Lake Paro. A shrub species, Salix koreensis, is the most common. Tall grass type is dominant occupying the most vegetation zone of the tributary channels. Phragmites japonica is absolutely dominant. Due to its dense cover, a few plant species are co-existed. Otter activity was found in all three vegetation types and no marked activity was found at some sites of tall grass type. There is no difference in species composition and physiognomy between tall grass sites with and without otter activity, while it shows significant difference in fish availability between two groups. Overall we found that home range of otters in the region is along the mainstream and downstream of tributary streams with high fish availability in all vegetation types and in various human activity levels.

한강 하류의 남조류 및 환경요인의 연간 (2000 ${\sim}$ 2003) 변화에 대하여

서미연,김백호,배경석,한명수,Suh, Mi-Yeon,Kim, Baik-Ho,Bae, Kyung-Seok,Han, Myung-Soo 한국하천호수학회 2005 생태와 환경 Vol.38 No.2

한강 중하류의 남조류 및 환경요인의 연간변화 (2000 ${\sim}$ 2003)를 파악하기 위하여, 2000년 4월부터 2003년 10월까지 4년간 성수대교에서 성산대교까지 총 5개 지점을 선정하여, 수계의 기초환경요인 및 식물플랑크톤 현존량 변화를 조사하였다. 조사기간 동안, 남조류의 현존량은 점차적으로 감소하여 장기간 강우가 가장 많았던 2003년에는 거의 관찰되지 않았으며, 총 식물플랑크톤 현존량에 대한 남조류의 기여도는 약 10%범위내였다. 이러한 현상은 매년 강우집중기 동안 팔당댐으로부터 많은 방류수가 유입됨으로서 수온감소는 물론 광량감소, 영양염류 희석 등에 의한 남조류의 성장이 제한된 것으로판단되며, 동일시기에 다른 조류 (녹조, 규조 등)의 높은 성장으로 엽록소 a와 식물플랑크톤 현존량이 뚜렷하게 증가하였다. 따라서 한강 하류의 고온기 동안 남조류 성장은 잦은 강우와 방류에 의해 제한을 받지만 규조나 녹조와 같은 다른 조류들의 높은 성장으로 대치되는 천이현상을 보였으며, 기후영향을 크게 받는 전형적인 하천생태계의 특성을 나타냈다. For 4 years (2000 ${\sim}$ 2003), annual fluctuations of standing crops of cyanobacteria and physicochemical factors were examined at five sites from Bridge of Seungsoo to Bridge of Seungsan in the lower part of Han River. The cyanobacterial abundance (ND to 4,167 cells $mL^{-1}$) was strongly decreased during the heavy rains in every year. During the similar periods in 2003, cyanobacteria hardly observed, and comprised below of 10 percentage of total phytoplankton. In the period of little cyanobacteria, some green algae and diatom dominated the phytoplankton community, while the concentration of chlorophyll a has not largely change. These results indicate that heavy frequent precipitation strongly limited the growth of cyanobacteria, and lead an algal succession by the appearance of new algal groups.

가속실험을 이용한 상업적 멸균처리 한식 탕반류의 유통기한 평가

한경수,이은정,홍상필 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.2

The objective of this research was to estimate the shelf-life of 4 kinds of Korean soup (Yukkaejang, Sagol-woogeojitang, Kalbitang, and Seolleongtang), under an accelerated experiment, based on the changes in the selected physico-cliemical, microbiological and sensory characteristics. The 4 kinds of Korean soup (Yukkaejang, Sagol-woogeojitang, Kalbitang and Seolleongtang) were treated at 121℃: for 30 min. and the shelf life was evaluatcdthrough accelerated experiment, based on the changes in the physico-chemical, microbiological and sensory characteristics. No viable cells were detected in any of the treatments and no significant differences were shown in pH, T13A and Hunter's color values for 3 weeks at 37℃. The periods found to he acceptable by sensory evaluation were 7 days for Yukkaejang and Kalbitang, 14 days for Sagol-woogeojitang, and 21 days for Seolleongtang. For an assumed Q_(10) value of 2.5, shelf-life was predicted as 109 days for Yukkaejang and Kalbitang, 219 days for Sagol-woogeojirang, and 328 days for Seolleongtang at 5℃, suggesting that these 4 hinds of Korean soup are suitable for commercial distribution.

小豆收量에 미치는 諸形質의 影響

韓鏡秀,張權烈,高美錫 진주농과대학 1970 진주농과대학 연구논문집 Vol.- No.9

小豆의 收量에 影響하는 形質을 正確히 알기 爲하여 形質相互間의 相關關係 그리고 經路係數分析과 各形質相互間의 表現型共分散, 遺傳共分散, 環境共分散 등을 計算하고 여러가지 選拔指數를 作成하여 選拔實驗을 한바 그 結果를 要約하면 다음과 같다. (1) 各形質相互間의 表現型共分散의 값보다 遺傳共分散의 값이 大體로 크고 環境共分散은 그 값의 變動이 甚하다. (2) 遺傳相關의 값이 表現型相關보다 높으며 開花日數와 1株重量, 莖長과 1株重量, 莖直徑과 分枝數, 莖直徑과 1株重量, 莖直徑과 100粒重, 分枝數와 1株重量, 1株重量과 100粒重間에는 높은 正의 相關을 보였고 收量과는 莢數만이 높은 正의 相關을 보였다. (3) 收量에 미치는 諸形質의 直接的 影響을 보면 莢數, 莖直徑, 100粒重, 莖長, 開花日數의 順으로 收量에 正으로 影響하며, 間接的 影響을 보이는 形質은 主로 莢數는 分枝數의 增加로 收量에 間接的으로도 影響하는 것을 알수 있다. 그리고 莖直徑은 開花日數, 莢長, 分枝數, 1株重量, 100粒重과 間接的으로 作用하여 收量에 影響하고 1株重量은 莖直徑, 莢數, 100粒重의 3形質과 100粒重은 開花日數, 莖直徑, 分枝數, 1株重量, 100粒重과도 間接的으로 影響을 미치는 것을 알수 있다. (4) 各形質을 選拔對象 形質로 하여 選拔指數를 作成한바 第3表 및 第4表와 같이 形質의 組合에 따라서 選拔에 관여하는 各形質의 加重値(weight)는 다르나 부호는 大體로 同一하다. (5) 選拔指數에 依한 遺傳的 進展과 그의 關係效率을 본바 單一形質에 있어서는 莢數, 1株重量, 100粒重의 效率이 높고 單一形質보다 2個形質을 2個形質보다 3個形質을 選拔對象形質로 하여 選拔하는 것이 效果的이라는 것을 알수 있다. 以上의 結果를 미루어 보아 小豆의 形質中 莖長, 莖直徑, 莢數, 100粒重의 4個形質이 收量에 直接 또는 間接으로 影響하는 重要形質이 될 수 있을 것으로 믿는다. 그리고 小豆에 있어서는 莖長(X₂), 莖直徑(X₃), 莢數(?), 100粒重(??)의 4個形質中에서 2-3形質을 選拔對象形質로 하여 選拔指數를 作成하여 選拔에 應用하는 것이 時間과 勞力 그리고 選拔效果面에 있어서 效果的일 것으로 믿는다. The studies were intended to clarify the correlations between the characters and the influences of each character upon yield of Adzuki beans. The analysis of covariance was conducted to obtain the genotypic correlations among eight characters-days to flowering, stem length, stem diameter, number of branches per plant, number of pods per plant, plant weight, 100 grain weight and grain weight(yield), etc., and the path-coefficients were calculated by Dewey's method. Selection indexes were calculated by phenotypic and genotypic covariances between the characters, and genetic advances and relative efficiency were also calculated for these characters. The results obtained are summarized as follows: (1) The yield of Adzuki bean was mainly associated with the character, number of pods per plant. (2) The values of genotypic covariances were slightly higher than those of phenotypic covariances between the characters. (3) Stem length, stem diameter, number of pods per plant, and 100 grain weight had a direct positive influence upon the yield of Adzuki beans. (4) Number of branches per plant and total plant weight had little or negative influences upon yield but it had rather considerable indirect influence upon yield by increasing the other characters. As a result, it can be concluded that Adzuki bean yield is primarily determined by increasing number of pods per plant, in turn the yield of Adzuki bean is secondarily determined by the number of pods per plant. (5) Many selection indexes which contain 1-7 characters in calculation were obtained as shown in Tables 2 and 3, and they show the genetic advances and relative efficiency which were calculated with various selection indexes. These results suggest that selection index technique is useful in Adzuki bean breeding. In reality, however, as the selection index varies with population and environment in which the population is located. Inspite of the expected usefulness of selection index technique in Adzuki bean breeding, unsolved problems such as the expense, time and labor involved in calculating the selection index remain. For these reasons and from these studies, it was realized that the selection index for the selection should be calculated on the basis of the data of some 3-4 characters, stem length, stem diameter, number of pods per plant, and 100 grain weight, etc. These characters should be very useful agronomic characters in the selection of Korean Adzuki beans, as they could be measured or counted easily thus saving time and expense, and have a greater effect on more Adzuki bean yield than the other agronomic characters.

외식 통계 계정 필요도 분석

한경수,홍소야,서경미 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1

The purpose of the study to examine the requirement of food service statistical account. the questionnaire was composed of two part: the traits of food service statistical accounts by USA and Japan and demographic characteristics. 325 questionnaires were distributed by mail to the member of Korean Food service Management Society and Korea university and college Culinary Management Faculty Association and 92 questionnaires were returned. the data was completed using the SPSS for frequency, mean, t-test, and ANOVA test. As a result of the follows. the 23 traits showed a high priority placed. Seeing the category, Number of customer, unit volume, solid waste, and information technology and application were higher than employee information. Comparing company members to academic members, both of them thought that dimension of unit, sales result, and number of customer. However, company member group indicated that employee information was important.

활동기와 동면기 살모사의 위장관 점액세포내 점액질에 관한 조직화학적 연구

한현주,박래백,임영민,김효성,박경수,노영복 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

살모사(Aekistrodon halys Pallas)의 위장관 점액세포내 점액질을 활동기와 동면기로 나누어 조직화학적으로 비교관찰하였다. 일반관찰을 위하여 H-E 염색을, 조직화학적 소견을 관찰하기 위하여 PAS reaction, Ab2.5 염색, AB1.0염색, AB2.5-PAS 염색, AB1.0-PAS 염색 AF1.7 염색 및 AF1.7-AB2.5 염색등을 시행하였다. 위(胃)는 표면점액세포와 점액경세포의 점액질을, 소장은 은롸롸 융모의 점액세포를 관찰한 결과를 다음과 같이 요약하였다. 1. 활동기와 동면기의 위점막에서는 현저한 차이는 없으나, 소장점막은 동면기에는 점막 주름수가 감소하고 높이가 낮아지며 점액세포가 위축되었다. 2. 위 표면점액세포는 활동기에 중성점액질과 약간의 Sialomucin을 포함한 산성점액질로 구성되었으나, 동면기에는 중성점액질과 Sialomucin이 약간 감소하였다. 3. 위 점액경세포는 활동기에 중성점액질만을 포함하고 있었으나, 동면기에는 Sialomucin을 포함한 산성점액질이 소량 검출되었다. 4. 소장 점액세포는 활동기에 산성점액질과 중성점액질로 구성되었으며 산성점액질에는 Sulfomucin과 Sialomucin이 포함되어 있었으나, 동면기에는 Sulfomucin과 Sialomucin이 다소 감소하였다. This study was performed in order to investigate the histochemical properties and compositions of the mucosubstances in the mucous of the gastrointestinal tract of Vipers, Agkistrodon halys Pallas, in active and hibernating phases. The specimens from stomach and small intestine were fixed in 10% neutral buffered formalin, embedded in paraffin wax, sectioned at a thickness of 4㎛, and stained with Hematoxyling-eosin for general histological observation and with PAS reaction, Alcian blue pH 2.5 or 1.0, Alcian blue pH 2.5-PAS or 1.0-PAS reaction, Aldehyde fuchsin pH 1.7, and Aldeliyde fuchsin pH 1.7-Alcian Blue pH 2.5 for histochemical finding. The mucous compositions in mucous cells of the gastrointestinal tract examined by their stain reaction were neutral mucin, acidic mucin, sulfomucin, sialomucin, The results obtained were as follows; The folds of the gastrointestinal tract in the hibernating phase, compared with the active phase, shrink and lower. Also, the shrinkage of epithelial cells were observed in the hibenating phase. The surface mucous cells of the stomach in the active phase composed mainly neutral mucin and a little amount of acidic mucin including sialomucin, but in the hibernating phase neutral mucin and sialomucin slightly decreased. The mucous neck cells of the stomach in the active phase constituted mainly neutral mucin, In the hebernating phase the mucous neck cells were composed of neutral mucin and a little amount of acidic mucin contained sialomucin. The mucous cells of the small intestine in the active phase consist of neutral mucin, acidic mucin including sulfomucin and sialomucin but in the hibernating phase sulfomucin and sialomucin slightly decreased.

조직확장기 사용의 임상적 고찰

한흥수,김우경,김수신,백세민 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

Recently, soft tissue expansion technique using tissue expanders has become a popular method for reconstruction of soft tissue defect because it provides high quality tissue with similar color, texture and hair bearing characteristics without significant donor site problems. During the period September, 1983 to December, 1988, we used tissue expanders to treat 36 patients with soft tissue defect, 3 scalp, 10 face, 6 neck, 4 trunk, 10 upper extremity, 3 lower extremity and evaluated the operative techniques, results and complications as follows. 1. We achieved favorable results in 31 cases(86.1%), especially in scalp, face and upper extremity, but poor results in lower extremity, especially below knee in location. 2. We experienced major complications in 2 cases(5.6%) such as implant exposure and minor complications in 7 cases(19.4%) such as hematoma, partial necrosis, infection, underlying bony depression etc. 3. Capsular excision is not desirable, but capsular release may permitted to acquire maximal length of the advancing flap. 4. In case of microtia, expanded tissue which was obtained from expanders is defficient for elevation of framework without skin graft. 5. Accurate and meticulous preoperative evaluation is the most important factor in achieving good and results.