서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

성공적인 한국 기업집단의 경영체제 특성과 미래 방향 모색

이경묵(Kyungmook Lee),홍길표(Kil-Pyo Hong) 한국인사조직학회 2014 인사조직연구 Vol.22 No.1

본 논문에서는 세계적인 경쟁력을 가진 한국 기업집단의 경영체제를 분석함으로써, 경영체제상의 한국 기업의 성공요인을 찾아내고, 이를 바탕으로 한국 기업의 경영체제가 지향할 방향을 제시하고자 한다. 이를 위해 먼저 한국기업의 경영체제 특성을 연구하기 위한 핵심주제와 그 현상특성에 대해 개관하였고, 이를 기반으로 사례연구의 분석관점을 구성했다. 사례연구는 세계적인 경쟁력을 갖춘 한국 기업집단인 삼성그룹, 현대기아차그룹, 포스코그룹을 대상으로 수행했다. 사례연구를 바탕으로 한국의 대표적 기업집단이 세계적인 기업집단으로 도약하는데 기여한 경영체제상의 세 가지 특성을 도출하였다. 첫째, 세계적인 기업을 만들겠다는 원대한 비전과 강렬한 의지를 가지고 있으면서도 동시에 주력사업의 핵심성공요소를 잘 이해한 뛰어난 그룹 최고결정권자가 존재했다는 점, 둘째, 이들이 장기간 기업을 이끌면서 막강한 권한을 행사할 수 있도록 지배기반을 제공한 계열사간 복합적인 소유구조와 계열사간 관계를 유지할 수 있었다는 점, 셋째, 그룹 최고결정권자의 리더십 및 소유구조 특성에 적합한 그룹경영시스템을 구축하여 그룹 임직원들의 역량을 결집해 나갔다는 점 등을 들 수 있다. 이들 사례가 다른 한국기업에 던지는 시사점으로 본 연구에서는 주력사업의 핵심성공요소를 잘 이해하면서도 세계 일류기업을 만들겠다는 강한 의지를 가진 최고결정권자의 육성과 검증, 장기적인 관점에서의 비전경영, 조직의 각 부문과 임직원들이 그룹 최고결정권자의 강한 의지에 맞게 행동하도록 하는 그룹경영 시스템의 구축이 필요하다는 점을 제시하였다. This paper aims to identify the success factors in the governance systems of Korean corporate groups and suggests the future directions of the governance systems of Korean firms by analyzing three successful Korean corporate groups: Samsung, Hyundai-Kia Motors, and POSCO. In order to analyze their governance structures, we developed a two-by-two matrix framework to identify their key governance system characteristics. In one dimension, we distinguish non-Chaebol corporate groups from Chaebol type. In the other dimension, we identify vertically-integrated corporate groups with a single core business from diversified corporate groups with multiple core businesses. Samsung group is a Chaebol type corporate group with multiple core businesses, while Hyundai-Kia Motors group is a Chaebol type corporate group with a single core business. POSCO group is a non-Chaebol corporate group with a single core business. Then, we describe the governance systems of each corporate group in detail. We collected data mainly by interviewing multiple executives of those groups. Samsung group is the largest and most successful Korean corporate group so far. It has grown very fast and has become a world-class corporate group under the leadership of group Chairman Kun-Hee Lee. Key characteristics of Samsung’s governance system can be summarized as follows. First, the role of Chairman Lee has been critical in Samsung’s success in the global market. He had a very strong will to transform Samsung into a world-class corporate group, provided an audacious vision to organizational members of the Samsung group, and suggested basic direction to transform the group by using his business insight. He directed the group with a long-term vision and deep understanding of the critical success factors of Samsung’s major businesses. Chairman Lee’s vision has been implemented by a very powerful group headquarters and by professional managers. The group headquarters coordinates and integrates decisions of affiliate companies to pursue group level optimization. The headquarters exerts a strong influence on nominating directors and executives of affiliate companies, and is involved in major investment decisions of the affiliates. Executives of affiliate companies are nominated on the basis of their own performance as well as of the performance of the organizational unit they work for. Monetary compensation of organizational members is very tightly linked with business performance and thus the incentives of stockholders, executives, and the rank-and-file are tightly aligned. This tight incentive alignment helps Samsung concentrate efforts of its employees to achieve the vision of Chairman Lee. The Hyundai-Kia Motors group has emerged as a major player in world automobile industry under the leadership of Chairman Mong-Ku Chung. Similar to Samsung’s Chairman Lee, Chairman Chung had a very strong will to build up a world-class automobile corporate group, provided an audacious vision, and dictated the quality improvement as the most important success factor in the automobile industry. While Chairman Lee delegates most of his decisions to professional managers in Samsung, Chairman Chung remains involved in major decisions of his affiliate companies. Chairman Chung has practiced “management by wandering around.” He has frequently visited major places of his concern and checks whether his vision is being properly implemented. Group headquarters does not play a major role in group-level governance in this group but provide decision support services to Chairman Chung and the CEOs of affiliate companies. While a very large portion of executives in affiliate companies of Samsung group are trained in managerial functions such as finance, accounting, human resources management, and auditing, the majority of executives in the Hyundai-Kia Motors group are trained in assembly, quality control, sales and marketing, and R&D.

범법 정신 장애자와 일반 정신 장애자의 약물 사용 양상에 관한 비교 분석

이길홍,박두병,나철,이재광,기백석,이재우,유영식,이영식,이헌재 중앙대부설한국의과학연구소 1991 한국의과학 Vol.23 No.1

범법정신장애자의 정신의학적 특성분석

이길홍,이재광,박두병,나철,기백석,이재우,유영식,이영식,이헌재 중앙대부설한국의과학연구소 1991 한국의과학 Vol.23 No.1

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

頭痛에 관한 精神醫學的 硏究

羅澈,李吉弘,李在光,奇柏錫,李在禹,兪英植,李永植 서울醫大 1990 精神醫學 Vol.15 No.3

류마티열의 임상적 고찰

이재호,길홍량 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

In a group of 25 children with acute rheumatic fever and rheumatic carditis who had been admitted to the department of Pediatrics, Chungnam University Hospital during the period of 3 years and 6 monthes from Jan. 1983 to June. 1987, clinical observation was made. The results were as follows; 1) The highest incidence was the age group of 10 to 15 years, and male to female ratio was 1 : 1.27. The percentage of total patients of admission was 1.2%. 2) The highest seasonal incidence was seen in winter (44%) 3) Major clinical manifestations were as follows. a) Carditis occurred in 96% of cases. b) polyarthritis 36%. c) Erythema marginatum 12%. but Chorea and Subcutaneous nodule were not observed. 4) Laboratory examinations showed anemia in 40% of cases, positivity of C-reactive protein in 88% and leukocytosis in 50'%. ASO titer and ESR were elevated in 80% and 72%. 5) Relapse rate was 24% and most, of them was occur red within 5yr of 1st attack (84%). Mortality rate was 84%. 6) C-reative protein and ESR was to be normalized after 3 to 4 weeks of treatment in both Aspirin treatment alone and Aspirin-Steroid combinated treatment group. But leukocytosis tended to be increased in Aspirin-Steroid combinated treatment group.

용치 놀래기, Halicoeres poesilopterus(Temmink et Schlegel) 생식생태

이영돈,노홍길,이택열 제주대학교 해양연구소 1991 해양자원연구소연구보고 Vol.15 No.-

청소년 정신장애에 관한 정신의학적 연구

이길홍,김헌수,나철,민병근 중앙대부설한국의과학연구소 1983 한국의과학 Vol.15 No.2

鑄鋼補修熔接의 冶金學的 考察

李孝福,李吉弘,秋現植 조선대학교 기초과학연구소 1987 自然科學硏究 Vol.10 No.1

In this paper, the metalIurgical analysis of repairweldings which is used the five kinds of welding-rod was investigated. Especially, it surveyed the metal structure in order to find out which one among the five welding-rods similar to base metal SC-42, tire mould. Main analytical results could be summmerized as follows: 1) Soft steel usually is used to the soft steel welding-rod but the analytical results could be found that it is better to use the high strength steel than to use the soft steel welding-rod. 2) Base metal SC-42, tire mould is much better to use LC-300 than to use SC-200 or LH-100 welding-rod, because both are the same cost but the mechanical properties of LC-300 weldingrod is superior to SC-200 or LH-100 3) It is appropriate to use the LC-300 or LC-318 welding-rod to do the difficult repair-weldings because these are the same metal structure without the thermal treatment.