Productivity Loss of Rheumatoid Arthritis Patients according to the Their Stages of the Disease Activity Score

( Sang-Cheol Bae ),( Jin-Hye Cha ),( Jung-Yoon Choe ),( Sung Jae Choi ),( Soo-Kyung Cho ),( Won-Tae Chung ),( Chung-Il Joung ),( Young-Ok Jung ),( Young Mo Kang ),( Dong-Wook Kim ),( Jinseok Kim ),( Y 대한류마티스학회 2018 대한류마티스학회지 Vol.25 No.2

Objective. Productivity loss was compared by 3-stage of disease activity and associations between higher disease activity and high productivity loss were identified. Methods. Data were extracted from Rheumatoid Arthritis (RA) Patient-reported Outcomes Research, which enrolled 2,000 RA patients (>20-year) on disease-modifying-antirheumatic-drugs (DMARDs) (≥ 6-month) from December 2012 to June 2013. This included 1,457 RA patients with the disease activity score (DAS-28-ESR) in their medical charts. Productivity loss in time and indirect cost was estimated using The World Health Organization Health and Work Performance Questionnaire (HPQ). Baseline characteristics and productivity loss outcomes were compared according to DAS-28-ESR groups. Results. 84.4% were females, 54.2% had low DAS-28-ESR (<3.2), and 38.2% and 7.6% had moderate (3.2∼5.1) and high DAS-28-ESR (>5.1). Patients with moderate to high DAS-28-ESR had higher lost productivity time (LPT) and monthly costs of LPT than those with low DAS-28-ESR (time in hours: 110.0±58.4 vs. 132.4±57.2 vs. 71.5±52.0, p<0.0001; monthly costs of LPT in 1,000 Korean won: 1,097±607 vs. 1,302±554 vs. 741±531, p<0.0001). Multiple regression analyses revealed significant associations with high LPT in high (adjusted odds ratio [OR]=3.87, 95% confidence interval [CI]: 2.18∼6.87) and moderate DAS-28-ESR (adjusted OR=1.88, 95% CI: 1.41∼2.52) compared to low DAS-28-ESR. In addition, positive associations with high monthly costs of LPT were observed in high (adjusted OR=3.45, 95% CI: 1.98∼5.99) and moderate DAS-28-ESR (adjusted OR=1.93, 95% CI: 1.43∼2.54) compared to low DAS-28-ESR. Conclusion. Timely therapeutic strategies should be taken into consideration given that the RA patients with moderate to high DAS-28-ESR showed strong associations with high productivity loss for effective management of RA. (J Rheum Dis 2018;25:122-130)

Implementation of UPT Service in WIN-Based Mobile Communication Networks

Yun Won Chung(정윤원),Min Young Chung(정민영),Dan Keun Sung(성단근),In Jeong Kim(김인정),Jung Keun Shin(신정근),Sung Kim(김성) 한국통신학회 1999 한국통신학회 학술대회 및 강연회 Vol.1999 No.4

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

한국의 광물명칭에 관한 연구

정원우,상기남,이윤종,김중욱,곽기근 慶北大學校 科學敎育硏究所 2003 科學敎育硏究誌 Vol.27 No.-

The purpose of this study is to investigate historical records on Korean mineral terms. One of the earliest records on Korean mineral terms is the Donguebogam(oriental medical handbook) written by Heo Jun in 1613. Most of geological investigation of Korea was accomplished by Japanese geologists in the period of the 1900~1945. Korean mineralogical records have been described by Gottsch(1886), Kwasaki(1935), Kinosaki(1937, 1940), Tsuda(1941, 1952) and Galleger(1963). Korean mineral species have been described about 300 species by KIER(Korea Institute Energy and Resources) in 1977. In the results of this study, Comparisons and classifications between current korean mineral terms and korean traditional and chinese medical mineral terms are suggested.

농촌인의 건강실태에 관한 연구

정동춘,정성태,장창현,전태원 師範大學 體育硏究所 1993 서울大學校 體育硏究所論集 Vol.14 No.2

The purpose of this study was to investigate the health condition of rural area adults. To accomplish this purpose 98 adults were drawn from 2 different rural areas such as Chungnam and Junbook, and their health condition were examined. The data from these people were compared with those of 108 Seoul residents. The main findings of this study were as followings; 1. Neuralgia was the commonest disease in rural area adults, followed by Rheumatism, waist pain, and heart problem. 2. About 62% of rural area adults indicated that their average sleeping time was less than 7 hours per day. 3. About 48% of rural area male adults indicated that their daily labor was generally “severe,”while 61.3% of female adults said in the same way. 4. The blood pressure value of rural area males was 124/73 ㎜Hg, while that of urban area males was 114/77 ㎜Hg. 5. The values of GOT and GPT were higher in rural area males than in rural area females. 6. the value of cholestrol was lower in rural area adults than in urban area adults.

농촌인의 체격 및 체력 실태에 관한 연구

정성태,장창현,전태원 師範大學 體育硏究所 1993 서울大學校 體育硏究所論集 Vol.14 No.2

The purpose of this study was to investigate the physique and physical fitness of the rural area adults. To accomplish this purpose 202 adults were drawn from 4 different rural areas such as Chungnam, Junbook, Kyoungbook, and Chungbook, and their physique and physical fitness were measured. The data from these people were compared with those of 114 Seoul residents. The findings of this study were as followings; physique 1. The heights of rural area adults were shorter than those of urban area adults by about 4cm, and their heights tended to reduce by 2cm every 10 year as they got older. 2. The weights of rural area male adults were lighter that those of their urban counterparts by about 6kg ; rural area female adults were also lighter than their urban counterparts by 10kg. 3. The sizes of waist girths of both the rural area adults and urban area adults tended to increase after their 40s. physical fitness 1. There was no significant difference of grip strengh between rural and urban area male adults; rural area female adults exhibited stronger grip strengh than their urban area counterparts by about 4kg. 2. There was no significant difference of sit-up performance between rural and urban area male adults; rural area female adults showed weaker sit-up performance than their urban counterparts. 3. There was no significant difference of trunk bending performance between rural and urban area male adults; rural area female adults showed more flexible trunk bending performance than their urban counterparts.

필터프레스를 위한 영상 원격 제어 시스템 개발에 관한 연구

원충상,최영규 忠州大學校 2012 한국교통대학교 논문집 Vol.47 No.-

Existing, widely used industrial controller programmable logic controller (PLC) using the high cost and maintenance was a difficult problem. In addition, the network configuration was not easy. Thus, the filter press by video remote control and management to improve productivity and shorten maintenance time. Variety of smart devices (smart phones, iPad, tablet PC, etc.) Remote control is possible by utilizing the existing controlled by the PLC addresses maintenance and improved performance compared to that of possible filter press control and management system was developed.

PLD를 이용한 교통제어 시스템 설계

元忠常 忠州大學校 1999 한국교통대학교 논문집 Vol.34 No.2

For the purpose of the traffic smoothness of the crossroad, this paper construct a car sensor, that classify the heavy traffic direction into the smoothness direction, in the smoothness direction. If the sensor sense no signal the traffic continuously in the heavy traffic. Therefore the traffic increment efficiently. And using by the programmable logic device, we design th traffic controller with small size and economically

영남지역 납석 광상에 수반된 다이야스포아의 특성

정원우,상기남,이윤종 경북대학교 과학교육연구소 1996 科學敎育硏究誌 Vol.20 No.-

Mineralogy of diaspor in a pyrophyllite deposit in the Youngnam area has been studied by the methods of field investigation and laboratory works. Samll nodules of diaspore are present in a pyrophyllite deposit at Tongnae-Yangsan and Miryang area. Pyrophyllite-kaolin in this zone is accompanied by sericite, diaspore, mixed-layer mica/smectite, alunite, dumortierite and silica minerals. The pyrophyllite forms a lens-like body in a northerly-trending belt of rhyolitic flows and pyroclastic rock near the intrusion of granite rock of Bulkusa Series. The diaspore nodules occurring sporadically throughout the deposit contain platy diaspore and interstitial pyrophyllits. The nodules range in size from 1 ㎝ to 10 ㎝. Microprobe analyses, opitical data and unit-cell dimensions of the diaspore and pyrophyllite are given. Alteration of the original rhyolitic welded tuff exists along shear zones acting as channels for acid sulutions derived from Late Creataceous pluton. The formation of the pyrophyllite lenses involved outward migration of silica and alkalies, leaving behind less mobile alumina; short-range trasport of aluminum in solution is indicated by the diaspore nodules. by rate thin veins containing platy pyrophyllite, and by veins of massive pyrophyllits cutting silicified rhyolitic welded tuff at the termination of some shear zones. Published experimental work shows that the pyrophyllitization may have taken place within the temperature range of 350-370℃ under a pressure of 1 kbar or less. zones. Published experimental work shows that the pyrophyllitization may have taken place within the temperature range of 350-370℃ under a pressure of 1 kbar or less.