서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

位相反轉回路를 使用한 二重平衡變調器의 動作特性에 關한 硏究

文相在 경북대학교 공과대학 1977 工大硏究誌 Vol.6 No.-

位相反轉回路를 使用한 트렌스레스 二重平衡變調器의 變調效率 및 分離度를 解析하고 實驗的으로 고찰하였다. 實驗直가 理論直에 잘 符合하며, 實驗結果 本 變調器의 特性도 良好하다. Modulation efficiency and isolation index of a transformerless double balanced modulator using a phase inverter are analyzed and investigated experimentally. The experimental results are in good agreement with theoretical calculations. Very appreciable characteristics of the modulator also are observed from experimental results.

탄성력이 관계되는 역학적 에너지 보존에 관한 지도상의 문제점과 개선 방안

문충식,윤성현,권재술 한국교원대학교 과학교육연구소 1991 청람과학교육연구논총 Vol.1 No.1

현행 고등학교 물리 교과서와 대학 일반물리학 교재에 나타난 용수철 진자의 진동에서 역학적 에너지 보존에 관한 기준점 설정의 불명확성과 오해의 소지를 지적하고 이를 해결하기 위한 방안을 제시하였다. 혼란이 생기는 원인은 근본적으로 좌표 기준, 위치 에너지의 기준 설정에서 나타나는 것으로써 군등장인 경우, 거리에 비례하는 위치 에너지(mgx)이므로 기준을 어디에 잡아도 무방하나 그렇지 않는 탄성 위치 에너지의 경우(1/2)kx^2에는 주의를 요한다. 본 연구는 기준 위치 설정에 따라 위치 에너지 표현식이 다름을 보이고 이를 고등학교 및 대학 일반물리학 수준에서 지도할 수 있는 방안을 제시하고자 한다. A typical representation of elastic potential energy is (1/2)kx^2, where x represents the distance from the spring's unstratched end point. However, this representation will be correct only in a particular situation that the origin of the coordinate and the reference point of the potential energy are at x=0. Without this condition, the potential representation, (1/2)kx^2, is no longer correct. In this study, the misconceptions found in high school textbooks and university laboratory manual were exemined and presented a improved method to teach elastic potential energy. The generalized form of elastic potential energy with arbitrary reference point in coordinate system as well as potential energy was derived. To adopt this idea in high school level, a graphical method of deriving the generalized form of elastic potential energy was devised.

The prediction of the tooth size in the mixed dentition for Korean

Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

Cisapride가 심근의 ATP-sensitive K 통로에 미치는 영향

문성기,인병현,김원호,고재기 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1

치근면 처치시 결합조직 부착에 관한 초기효과의 조직병리학적 연구

문상준,이종헌,이재현 단국대학교 치의학연구소 1993 논문집 Vol.5 No.-

An essential fact in the regeneration of new periodontal tissue after periodontal therapy is the reattachment of collagen fibers to the tooth. Two phenomena play a fundamental role in preventing new connective tissue attachment to the exposed root surface ; 1) The apical migration of the junctional epithelium 2) The contamination of cementum by toxic substances, especially endotoxins. Authors have used rat submucosal implantation of root sections to study the connective tissue healing to periodontally diseaed root, previously planed and demineralized with citric acid and tetracycline-HCI. The results were obtained as follows. 1. The connective tissue attachment was increased in tetracycline, citric acid, non disease, scaling and root planing order and inflammatory reaction was seen in the rat teeth, no treatment group. 2. Collagen fiber attachment at the dentin surface was more increased than cementum surface. 3. In 2 week of citric acid and tetracycline-HCI specimens, osteoid was seen near the fibrotic band. 4. In the MT view, collagen fiber formation was increased with time and the numerous collagen fiber and connective tissue was more densly attached to the tooth surfaces in the tetracycline-HCI group than the citric acid group.

연성하감

문상호,김재홍 한국의학사 2004 診斷과治療 Vol.24 No.4

하악전돌증의 악교정수술 후 연조직 형태변화에 대한 연구

성상진,박현도,김재승,문윤식 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.3

악교정수술에 관한 치료계획은 치료결과에 관한 정확한 예측을 바탕으로 수립되는 것이 바람직하며 이는 심미적인 결과를 얻기 위한 가장 중요한 요소 중에 하나이다. 성인에서 골격성 하악전돌증의 치료는 하악골후퇴술을 이용한 악교정수술법이 주로 이용되는데, 술후 턱끝의 돌출도가 과도하게 감소되어 하악전진이부성형술을 추가로 시행해야 하는 경우 하악골과 턱 부위의 연조직 변화방향이 상이하게 나타나므로 술후 연조직 변화를 정확히 예측하는데 한계가 있다. 본 연구에서는 골격성 하악전돌증을 주소로 악교정수술을 시행한 성인을 대상으로, 상행지시상분할골절단술(BSSRO)만을 시행한 경우(A군) 11명과 하악전진이부성형술(advancement genioplasty)도 같이 시행한 경우(B군) 9명의 경조직과 연조직 변화의 상관관계를 알아보기 위하여, 수술 8개월 이후에 채득된 측모두부계측방사선사진을 비교하여 다음과 같은 결과를 얻었다. 1. E-line에 대하여 상순은 더 돌출되고 하순은 더 후퇴되어 입술의 형태가 개선되었으며,하악전진이부성형술을 병행한 경우 하순의 돌출도는 더 개선되었다. 2. 두 군 모두에서 상순은 후방이동하고 비순각은 증가하였다. 3. 술후 B점에 대한 연조직 POGs점의 변화율은 A군에서 84%, B군에서 66%로 나타났으며 두 군간에 통계적 유의성이 있었다. 4. 경조직과 계측점의 수직변화량은 A군에서 감소하였다. The treatment plan for orthognathic surgery must be based on accurate predictions, and this can be produced the most esthetic results. Treatment of prognathic mandible in adult is usually orthognathic surgery using mandible set back, but mandible with retruded chin point is needed additional chin augmentation. In this case, the directions between mandible and chin point are different therefore, the prediction of soft tissue reactions must be modified. In this study, we materialize the patients who was taken orthognathic surgery due to prognathic mandible, 11each(Group A) was taken only Bilateral Sagittal Sprit Ramus Osteotomy (BSSRO), 9each(Group B) was taken additional advancement genioplasty. The lateral cephalometric radiography taken 8 months later after orthognathic surgery by this patients were used. The results of this study were as follows : 1.The profile of lips was favorable after surgery due to upper lip to E-line became prominent and lower lip to E-line was retruded. 2.In both group, upper lip moved posteriorly and nasolabial angle was increased. 3.The ratio of the soft tissue profile change in POGs point to skeletal B point movement was 84% in group A and 66% in group B, and there was statistical significance between group A and group B. 4.Vertical movement of hard tissue points is decreased in group A.

망간 노출 근로자의 정신 ·신경행동 양상에 영향을 주는 요인

문영한,권기련,김은아,김규상,김양호,김재우,노재훈,양정선,진영우 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

The risk posed to human health by environmental manganese (Mn) exposure is unknown. The purpose of this study is to establish if subclinical effects related to Mn exposure and examine the factors influencing psychoneurobehaviral outcomes of Mn exposed workers. This study involved 121 male workers of welding, alloy furnace, and manufacturing of welding stick. Study investigations include: a questionnaire covering demographic characteristics, job and exposure history and medical symptoms and conditions, monitoring workplace air for personal exposure to respirable and inhalable manganese, analysis of blood and urine samples, psychoneurobehaviral test(neurobehaviral core test battery(NCTB), signal change on magnetic resonance imaging (MRI) scans, minimental state and neurological examination). The main results of this study were as follows; 1. Preliminary results showed that, with increasing manganese exposure, neurobehaviral performance was poorer and signal change on MRI scans increased. 2. The results of examination revealed significant relations on psychoneurobehaviral outcomes (neurobehaviral performance, signal change on MRI scans, and neurological features). 3. In multiple regression, age and educational status as demographic variables and exposure level were significantly related to neurobehaviral test. Also exposure level and serum Mn concentrations were positively related to signal change on MRI scans and neurological features affected by Mn on the brain (signal change). 4. Psychoneurobehaviral outcomes from Mn exposure were related to neurobehaviral performance, signal change on MRI scans, neurological features and profile of mood states (POMS), and influenced positively with age, alcohol and smoking history, and duration of Mn exposure, negatively with educational status. Serum Mn concentrations in combination with brain MRI scans, and perhaps a battery of neurobehaviral tests, appear to be the best way to monitor excessive exposure to Mn. These results are consistent with our knowledge on Mn action on the brain and are similar to the type of neurobehaviral dysfunction. They suggest that there may be age, educational status, and life style (alcohol and drinking history) differences with chronic environmental exposure. These findings suggest further evaluation, particularly on relationships between Mn exposure, aging, and susceptibility factors.