서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

김수영의 문학적 좌표로서의 해방직후

김혜진 ( Hye Jin Kim ) 한국언어문화학회 2011 한국언어문화 Vol.0 No.44

The purpose of this article is to approach Kim Soo-young`s poetry and essays in 1960s as a new view beyond the fixed point that lots of studies have decided for the last several years. Most of the studies have concentrated on the historical event 4?19 revolution with Kim`s writing, but those universalized perspectives could not resolve some problems : First, Kim who had reacted to sensitively the incident remarked that writers defected to North Korea even if the situation that people exclaimed ``freedom`` and ``democracy`` at the revolution. The next, the blame toward literary friends interacted just after Liberation age at the 1960s. These problems seem to be insignificant at first sight, but just is the most internal core of Kim`s statements that appeared abruptly. The two problems above mentioned turn up in Kim`s literature as figures of poets Park In-hwan and Im Hwa. What the novel 〈A Volunteer Army〉 represents, Im Hwa is the ``revolutionist`` used to frequently be expressed"leftist poet", and he is the object of identification with Kim at the same time a ``gaze`` made a guilty conscience by failure to the identification with Kim who could not participated in revolution just after Liberation. Cause of the blame is also the guilty conscience that Im`s gaze aroused. His observational gaze that live phantom is a function as self-reflection not only about the revolution just after Liberation, but also the react to the following the Liberation(following the revolution). This reflection by failure of the revolution and ``following revolution`` is called at the ``following revolution`` 4?19 in 1960s. Kim constantly tried to identify himself living 1960s simultaneously following Liberation. And the symptom that revealed by that highly appraising writers defected to North Korea ``conscientious`` himself, and denouncing literary friends including the Park who confused ideologically and could react to anything still remain South like himself. Kim`s problematical remarks in 1960s was a symptom revealed in relation to revolution just after Liberation. His poetry and essays direct that he is constantly aware of Liberation age as the literary coordinate and the historical reference point, not only written rely on the affected passion by the 4?19 revolution.

‘진정성’이라는 거울에 비추어진 박인환

김혜진(Kim, Hye-Jin) 한국근대문학회 2013 한국근대문학연구 Vol.14 No.2

이 연구는 박인환에 대한 부정적 평가사가 어떠한 방식으로 형성되었는가에 대한 의문으로부터 시작한다. 박인환을 바라보는 관점이나 평가의 기준은 물론 연구사가 축적되어 오는 과정에서 다양한 방식으로 변화하여 오기는 했지만, 한편에는 여전히 그에 대한 부정적인 평가 및 발언이 유령처럼 자리하고 있기도 하다. 많은 연구자들이 인식하고 있듯 이와 관련된 김수영의 발언은 적지 않은 영향력을 행사하고 있다. 김수영의 문학사적 영향력이나 이후 그에 관한 연구사의 축적을 감안한다 하더라도 이점은 다소간 의문을 불러일으킨다. 김수영 발언의 중심에 있으면서도 명징하게 제시되지는 않는 어떤 것에 대하여 연구자들이나 독자들 모두 암묵적으로 동조하거나 감염되어 있었던 것은 아닐까. 이를 따지는 작업을 박인환에 대한 부정적 평가사의 내적 논리를 밝히기 위한 첫 번째 작업으로 삼고 김수영의 산문들을 먼저 살핀다. 특정한 시점에서 어떤 대상을 평하는 발언은, 대상 자체의 특성뿐 아니라 대상을 바라보는 발화자의 개인적·사회적 조건들과 밀접하다는 점을 고려하여 보면, 김수영이 박인환을 평하는 지점들이 1960년대 김수영 자신의 정신사적 문제와 더욱 밀접히 관련되는 것이라는 점이 드러난다. 그 과정에서 김수영의 발언들이 ‘진정성’의 원리와 부합하는 지점들을 따지고, 이 진정성이 ‘비판’의 형식으로써 드러난다는 점을 밝힌다. 비판의 수사학을 그 필연적인 도구로 사용할 수밖에 없는 구조를 지닌 진정성의 원리에서는, 사실 박인환은 물론 그 누구의 작품도 그 그물망을 빠져나가기는 어려울 것이다. 또한 대상은 물론 평가자 자신의 ‘참된 자아’를 근거로 하는 이 원리는 그 실정적인 준거항목들이 텅 비어 있기에 하나의 ‘관점’으로 자리매김하는 것도 어렵다. 그렇기에 이 글에서는 박인환의 시가 어떠한 ‘자리’에서 발화되며, 그 양상은 어떠한가를 물음으로써, 자아의 진정성이 아닌, 주체의 진실성의 영역으로 시선을 옮겨오고자 하였다. 박인환에 대한 부정적 평가사의 내적 논리를 묻고, 그것을 토대 삼아 새로운 관점을 제기함으로써, 박인환을 바라보는 방법 자체에 대해 생각해 볼 수 있는 기회를 마련하고자 한다. This study begins with the doubts surrounding the history of negative appraisals about Park In-Hwan. As many scholars of literature recognize, the most influential remark about Park is based on the prose by Kim Soo-Young. But are there special elements in Kim’s view making literary circles sympathize with him regardless of his influence stemmed from literary talent of him? Illuminating this question is the first phase to reveal the inner logic of negative appraisals about Park and Kim’s proses are studied for this work. In that process, the point on which Kim’s comments accord with the principle of ‘authenticity’ is pondered and it is considered that this authenticity is revealed as a form of ‘criticism.’ In the principle of authenticity, accompanying criticism as its inevitable form, no one’s work as well as Park’s could avoid this mesh of criticism. And this principle based upon ‘true self’ of evaluator, in addition to object of evaluation, can’t function as a ‘point of view’ because there are positive articles of criteria missing. So this study’s aim is to look at the area of veracity of subject, not of the authenticity of self, by inquiring where Park’s poems are articulated and how the aspects of them are. This study could give an opportunity to contemplate the way of regarding Park, by grasping the inner logic of history of negative appraisal about him and raising a new point of view on the basis of that.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

병원획득 Klebsiella pneumoniae 균혈증 분석을 통해 본 Ciprofloxacin 내성과 Extended-Spectrum β-Lactamase생성 간의 연관성

김미영,추은주,곽이경,송문희,나성수,송태준,김성혜,전재범,최상호,정진용,김남중,김양수,우준희,류지소 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

목적 : K. pneumoniae는 ciprofloxacin내성 증가가 전세계적으로 문제가 되고있는 extended-spectrum beta-lactamase (ESBL)를 생성하는 대표적인 세균으로 최근 외국에서 ciprofloxacin 내성과 ESBL 생성사이에 관련이 있다는 2-3편의 보고들이 있었다. 본 연구에서는 병원획득 K. pneumoniae 패혈증이 있었던 환자들을 대상으로 ciprofloxacin 내성과 관련된 인자를 알아보고자 하였다. 재료 및 방법 : 2001년 1월 부터 2002년 12월 사이에 2200병상의 3차 의료기관인 한 대학병원에서 입원 후 72시간 이후에 나간 혈액배양에서 K. pneumoniae가 배양된 입원환자를 대상으로 의무기록과 전산기록을 분석하여 환자의 성별, 나이, 병동, 기저질환, 이전의 항생제 사용력, 패혈증 발생당시까지의 재원기간, 이전 입원력, 원인균의ESBL 생성유무 등을 파악하였고 이들 변수가 ciprofloxacin 내성과 관련이 있는지를 분석하였다. 재발성 패혈증의 경우는 첫 번째 경우만을 분석에 포함하였다. 결과 : 연구대상 환자는 총154명이었고 K. pneumoniae의 ciprofloxacin에 대한 내성률은 28.6% (44/154)였다. Ciprofloxacin 내성균주 중 ESBL 생성균주의 비율은 95.5% (42/44)였고 ciprofloxacin 감수성균주에서 ESBL 생성균주의 비율은 24.5% (27/110)였다(P<0.001). ESBL생성외에 단변량 분석에서 유의한 관련을 보인 변수로는 남자, 나이가 많은 경우, 패혈증 당시 중환자실 재원, 기저질환이 고형암, 혈액암, 담도계 질환인 경우, 패혈증 발생이전 1달 이내의 항생제 사용력, 3세대 cephalosporin, metronidazole, fluroquinolone, carbapenem 투여력이 있었다. 다변량 로지스틱 분석을 시행 하였을 때는 나이가 많은 경우(Adjusted odds ratio[A0R]; 1.04, 95%confidence interval[CI]; 1.01-1.06)와 ESBL 생성(AOR; 81.35, 95% CI; 17.76-372.53)이 유의하게 ciprofloxacin 내성과 관련이 있었다. 결론 : 패혈증을 일으킨 병원획득 K. pneumonias에서의 ciprofloxacin 내성은 ESBL 생성과 유의한 관련을 보였고 향후 이에 관련된 원인이나 기전을 분석하기위한 분자역학적·분자생물학적 연구가 필요하겠다. Background : Strains of ciprofloxacin-resistant Klebsiella pneumoniae have emerged worldwide. We investigated the epidemiology of ciprofloxacin resistance and its relationship to ESBL production in nosocomial K. pneumoniae bacteremia. Materials and Methods : Using the computerized database of clinical microbiology, we identified all patients whose blood culture had yielded K. pneumoniae between January 2001 and December 2002 at a 2200-bed university-affiliated tertiary-care hospital. During the study period, total of 392 episodes of K. pneumoniae bacteremia were documented of which 163 episodes were acquired nosocomially. 9 cases of recurrent episodes were excluded. Results : The resistance rates to ciprofloxacin was 28.6% (44/154). ESBL-production was significantly more common in ciprofloxacin-resistant isolates than in ciprofloxacin-susceptible isolates (95.9% [42/44] vs. 24.5% [27/110], P<0.001). In univariate analysis, following factors were significantly associated with resistance to ciprofloxacin: older age, male sex, ICU admission at the time of bacteremia, prior use of antibiotics within 1 month before bacteremia, solid tumor, hematological malignancy, or biliary disease as underlying disease, and ESBL-production. The prior use of 3^(rd)-generation cephalosprins, metronidazole, fluroquinolone, or carbapenem were also risk factors. Independent risk factors for ciprofloxacin resistance were older age (adjusted odds ratio [AOR]; 1.04, 95% confidence interval [CI]; 1.01-1.06) and ESBL production (AOR; 81.35, 95% CI; 17.76-372.53). Conclusion : The close relationship between ciprofloxacin resistance and ESBL production was documented in nosocomial K. pneumoniae bacteremia. Further epidemiological and molecular studies to determine factors and mechanisms involved in the relationship are needed.

체계적인 액션러닝을 활용한 대학원 신입생 학교생활 지원 콘텐츠 개발 및 적용방안 탐색

김혜진,김혜나,김종민,강신범,남기곤,박수홍,강문숙 부산대학교 교육연구소 2012 교육혁신연구 Vol.22 No.3

기판 단차에 따른 감광제의 분포와 선폭 변화

김진영,오혜근 한양대학교 이학기술연구소 2002 이학기술연구지 Vol.4 No.-

최근 리소그래피 공정은 기판의 거대화와 더욱 작은 최소 선폭의 요구로써 감광제 최적의 두께와 균일도를 얻어야만 한다. 기판 위에 도포되는 감광제의 두께는 기판의 전체 범위에서 대체로 균일하다. 그러나 기판위의 단차에 도포된 감광제의 분포는 단차 주위에서 변화가 발생하며 이 변화는 단차의 크기와 형태에 따라 변한다. 작은 단차가 주기적으로 형성되어 있을 때 그 위에 분포되는 감광제의 절단면은 그 밑의 단차의 형태와 관련되는 방정식으로 정의된다. 우리는 이 논문에서 회전 도포시 강광제 표면을 예측할 수 있는 식을 찾기 위해 lubrication approximation을 적용하여 Navier-Stokes 방정식을 사용하였다. 마지막 감광제의 두께는 용매의 증발과 전열처리를 거치게 되며, 이때 감광제의 분포는 단차의 크기, 형태, 단차의 밀도에 따라 변했다. 우리는 이러한 영향을 지체적으로 개발한 리소그래피 예측 시뮬레이터인 LUV(Lithography for Ultraviolet)을 사용하여 단차 주위의 감광제 분포에 따른 선폭 변화를 통해 알아 보았다. The photoresist coating should be optimized in thickness and uniformity with larger substrate and smaller critical dimension. Resist thickness on a wafer can be roughly uniform, but thickness variation can occur around topology with the formation of a topology on a substrate. With a presence of a topology formed by narrow and periodic patterns, the photoresist thickness profile should be determined by an equation accountable for the underlying topography. To obtain the spun-on resist surface profile around a topographical feature, the equation combining mass continuity and Navier-Stokes equation using the lubrication approximation was used. The resulting thickness is changed with feature size, shape, density, and topology. The final dried resist thickness profile was obtained by applying the resist thickness reduction due to evaporation and soft bake. This non-uniformity in the resist thickness will affect critical dimension of the semiconductor device.

Lidocaine, Thrombin, Epinephrine 의 항균효과

김진우,이동건,전혜선,김승준,김석찬,안중현,김치홍,권순석,김영균,김관형,문화식,신완식,송정섭,박성학 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

목적 : 기관지내시경 검사에서 흔히 사용되는 국소마취제인 lidocaine과 내시경시 지혈목적으로 사용되는 thrombin과 epinephrine이 각종 균주에 미치는 항균효과에 대해 알아보고자 하였다. 재료 및 방법 : 균주는 가톨릭대학교 성모병원에서 2004년 3월부터 2004년 9월까지 임상검체 에서 동정된 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 각각 42, 42, 42, 43주를 대상으로 하였다. Lidocaine, thrombin, epinephrine 감수성 검사는 National Committee for Clinical Laboratory Standards (NCCLS, 2002)의 기준에 따랐다. 결과 : Lidocaine은 S. aureus, S. pneumoniae, P. aeruginosa에서 MIC_(50), MIC_(90) 모두 20,000 ㎍/mL 이었다. K. pneumoniae는 각각 10,000 ㎍/mL이었다. Thrombin은 S. aureus와 P. aeruginosa에서 MIC50 500 lU/mL 과 MIC_(90) 500 IU/mL 이상이었고, K. pneumoniae에서는 MIC_(50)과 MIC_(90)이 모두 500 lU/mL이상이었으나 S. pneumoniae에서는 MIC_(50)과 MIC_(90)은 125 IU/mL이었다. Epinephrine은 K. pneumoniae, S. pneumoniae에 대한 MIC_(50), MIC_(90)가 모두 >500 ㎍/mL이었고, S. aureus와 P. aeruginosa에 대한 MIC_(50), MIC_(90)가 모두 500 ㎍/mL이었다. 결론 : 기관지 내시경 검사에서 흔히 쓰이는 lidocaine, thrombin, epinephrine 등의 약제들이 호흡기 질환의 흔한 병원균인 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 균주들에 대해 항균 효과가 있을 수 있어 세균배양검사에 영향을 미칠 수 있겠다. Background : We performed this stody to find out about antimicrobial effect of lidocaine which is commonly used local anesthetic, and thrombin and epinephrine used for hemostasis during bronchoscopic procedures. Materials and Methods : The microorganisms that were cultured from specimens obtained during bronchoscopy were Staphylococcus aureus (n=42), Streptococcus pneumoniae (n=42), Klebsiella pneumoniae (n=42), and Pseudomonas aeruginosa (n=43) collected from St. Mary's Hospital, from March to Sep 2004 were used for susceptibity testing. Susceptibility to lidocaine, thrombin, and epinephrine were tested according to the National Committee for Clinical Laboratory Standards. Result : MIC_(50) and MIC_(90) of lidocaine for S. aureus, S. pneumoniae, P. aeruginosa were all 20,000 ㎍/mL and that for K. pneumoniae were 10,000 ㎍/mL. MIC_(50) and MIC_(90) of thrombin for both S. aureus and P. aeruginosa was 500 IU/mL and above 500 IU/mL, respectively; that for K. pneumoniae were all above 500 IU/mL and for S. pneumoniae they were 125 IU/mL, MIC_(50) and MIC_(90) of epinephrine for K. pneumoniae and S. pneumoniae were above 500 ㎍/mL; that for S. aureus and P. aeruginosa were 500 ㎍/mL. Conclusion : We observed possible antimicrobial effect of lidocaine, thrombin, and epinephrine in vitro against pathogens such as S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa, which are common respiratory microorganisms. The use of these agants could affect the result of bacterial culture.

이동 객체의 부분차원 스카이라인 검색 알고리즘

金鎭鎬,李慧明,朴永培 명지대학교 산업기술연구소 2008 産業技術硏究所論文集 Vol.27 No.-

Most of previous works for skyline queries have focused only on static attributes of target objects. With the advance in mobile applications, however, the need of continuous skyline queries for moving objects has been increasing. Even though several techniques to process continuous skyline queries have been proposed recently, they cannot process subspace queries, which use only the subset of attribute dimensions. Therefore it is not feasible to utilize those methods for mobile applications which must consider moving objects and subspaces simultaneously, In this paper, we propose a dominant object-base pruning method to compute subspace skyline of moving objects efficiently at query time and present the experimental results to show the effectiveness of the proposed method.

공학교육의 조별과제에서 직무배정에 따른 수강생의 학습만족도 변화에 대한 연구

김상균,이기욱,최성진,권혜진 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.B

The necessity of university's educational change is rising up, along with a social environment that keeps changing. This study deals with a newly educational style by recognizing the necessity of variance for engineering education, according to engineers' diversified roles within a company. The study was conducted by 7 members of middle-sized group, replaced from 5 members of small-sized and each was given his task by his job such as CEO, CMO, CSO, CIO, CCO, CQO or Auditor. On the basis of four theoretical backgrounds, this paper investigated students' level of learning satisfaction shown before and after task undertaking through a questionnaire and appraised the result made before and after task undertaking. This study is expected to improve a teaching method of university engineering education.