췌장염에 의한 가성낭종내에 생긴 가성동맥류 : 1례 보고

오연희,이채경,김승현,이성우,양창현,이정호,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

만성 췌장염의 합병증으로 생긴 가성동맥류는 드문질환으로, 반복적으로 다량의 출혈을 일으킬 수 있으며, 치료를 하지 않을 경우 사망율이 높기 때문에, 조기 진단과 치료가 필수적이다. 저자들은 38세 남자 환자에서 췌장염의 합병증으로 생긴 가성낭종내에서 발생한 가성동맥류 1예를 경험하였기에 보고하는 바이다. 가성 동맥류의 색혈류도플러상 낭종내에 양방향 흐름의 와류를 볼 수 있었다. Pancreatic Pseudoaneurysm within Pseudocyst from Pancreatitis: 1 Case Department of Diagnostic Radiology and Internal Medicine, College of Medicine,DongGuk University Yeon Hee OH M.D., Chae Kyeong Lee M.D., Seoung Hyeon Kim M.D., Sung Woo Lee M.D., Chang Heon Yang M.D., Jung Ho Lee M.D., Young Hyun Lee M.D. Pseudoaneurysm from pancreatitis is uncommon, but it can cause recurrent and massive hemorrhage. Because of high morbidity and mortality, early detection and treatment of the pseudoaneurysm is needed. We report a case of pseudoaneurysm within pseudocyst from pancreatitis. Color-flow Doppler sonography shows bidirectional flow and turbulent arterial flow, within anechoic mass.

The HBV DNA Amounts in Serum Have No relationship with ALT level and Hetergeneous Population Coexits in Chronic Hepatitis B Virus Infection

Chun, Yoon-Keun,Ha, Joo-hun,Hong-Jung-Woo,Oh, Soo-Myung,Kim, Sung-Soo 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Yoon-Keun Chun¹,Joohun Ha□Hong-Jung Woo□, Soo Myung Oh□,Sung Soo Kim□ ¹Department of Molecular Biology, College of Medicine,²Department of Surgery, college of Medicine,³Department of Internal Medicine, College of Oriental Medicine,and ⁴East-Weat Medical Reserch Institute,Kyung Hee University, Seoul, Korea. The HBV DNA Amounts in Serum Have No relationship with ALT level and Hetergeneous Population Coexits in Chronic Hepatitis B Virus Infection. Proceedings of International Symposium on East-West Medicine, Seoul. 212-230, 1999. -Hepatitis B is caused by hepadnavirus. Hepatitis B virus replicates through 3.5kb pregenomic RNA intermediate which is regulated by core promoter. Pathogenesis of hepatitis B virus has been bilieved the result of host immune response. But recently many studies have reported that high level of viral replication caused by mutation in core promoter might result in severs hepatitis. But these studies were performed in vitro, not in vivo. So there is yet debate about which factor, viral of host factor, is more important in pathogenesis of hepatitis B virus. So we measured real viral replication level in 204 chronic hepatitis B patients by quantifying HBV DNA from sera by our novel PCR-based more sensitive method, and compared these results with ALT level measured from same sera, which indicates liver cell damage. Surprisingly there are no significant correlation between HBV DNA quantity and ALT level. Then we cloned core promoter region. In SSCP, we found that many viral mutants coexist in one patient. Base on SSCP result, we chose main viral core promoter type in each patients, which is thought to determine overall viral replication level in this patient. Main type of core promoter region of each 41 patients were directly sequenced. And with these we measured promoter activity by luciferase assay system and compared promoter activity with on another. We found tha there were some differences in promoter activity according to core promoter sequences. And we constructed replication-competent viral constructs with core promoter from 41 patients and Transfected these into HepG2 cell and measured HBV DNA by southern blot. There were also differences in HBV DNA quantity according to core promoter sequences. On these all results we investigated correlation between the effect of HBV core promoter on viral replication in vitro and HBN DNA quantity, ALT level from sera of each patients. We found there is no significant correlation among them. As a result, we concluded that in determining severity chronic hepatitis B patients, host factors of each patient is more important rather than replicative activity of virus itself.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

경영자보상과 기업규모

정우성,오현미 부산외국어대학교 국제통상연구소 2000 國際經營論集 Vol.15 No.-

This paper empirically examines the relationship between compensation of corporate executive and firm size, industry. It menas that whether there are differences in the compensation by firm size and industry. And I examine whether compensation-peformance relationship are affected by firm size. A total of 1460 Korea Stock Exchange listed firms are selected as a test sample and 5 years (1992-1996) as an analysis period. Compensation variable is cash compensation and performance variable is ordinary income and sales are used as the dummy variable on the firm size. The results of this empirical study are as follows. First, the compensation is positively related the extent of firm size. Second, industry differences in cash compensation are investigated. Third, the relationship between compensation and performance is influenced by firm size. Conclusively, level of compensation of corporate executive is different by firm size and industry, and firm size is determinant of compensation-performance relationship.

사춘기 자녀와 어머니간의 커뮤니케이션에 관한 연구

오연옥,이정우 숙명여자대학교 생활과학연구소 1991 生活科學硏究誌 Vol.6 No.-

The children's gravity in a home is really great, so the education of children is an important problem. When they are in the infant days, the children are entirely influenced by their parents, but as soon as they are at paberty, they want to stand on their own legs with desire to find out the self. As a man who has character, they learn the responsibility to their activity through the communication. Also, they become defiant because they have mental troubles and can't adapt to the ideal and reality. We all hope to stabilize our home and grow the teenagers splendid, so the communication between parents and children is very important. The purpose of this study is to provide the basic imformation for the happy family life with the smooth communication between mother and the adolescent children work by analyzing the elements regarding the communication between mother and the adolescent children. The detailed contents of this study are as follows: 1) How general level of the communication satisfaction between mothers and their adolescent children is ? 2) How general level of the communication satisfaction in every low-ranking division is ? And how influence by socio-demographic factors(sex distinction, numbers of brothers and sisters, mother's education, profession and age, the level of home income). 3) How background variables influence independently mothers ans their adolescent children ? The research was inspected by 432 students of Girls' and Boys' High School in Seoul. As the means of the measurement, the questionaire was used and α=.61 as the result of Cronbach's Confidence Test. The questionnaires are composed for 30 days from the 25th of June. The data were analyzed by frequency, percentage, arithmetic mean, t-test, F-test, Duncan's Multiple Regression Test and Stepwise Multiple Regression Analysis. The results are summarized as follows: 1) The very satisfactory group is 26.2%, ordinary satisfactory group is 35.8% and undersatisfactory group is 38.0% in the communication satisfaction test between mothers ans their adolescent children. 2) The mean of the satisfaction is 3.41. Especially, the low-ranking divisions of the scholarly attainment, future aspiration, school life, making friends, social problems are more higher than total mean but the low-ranking divisions of the sex education, sex role, physical growth, valuation, family life are more lower than total mean. The children's communication satisfaction according to independent variables is significant. It showed high satisfaction in a home which has small number of children(p<.001) ans the high level of mother's education(p<.001). But mother's profession and age is partially significant. 3) The background variables influence the communication satisfaction between mothers and their adolescent children: mother's education is 35.7%, sex distinction is 8.5%, home income is 5.6%, number of brothers and sisters is 1.26%, mother's age is 1.28%. And they show totally 52.4%. As the above results show, in our country mother's concern about their children's scholary attainment and school life is great but they don't understand children's mental and emotional anxiety. So it is necessary to educate children through the communication in order to inspire them with the right valuation and firm subjectivity, because they are very important for the future of this country.

Mg-Fe 산화물계 NTC 서미스터의 特性

오영우,김현식,허정섭,이승관 경남대학교 신소재연구소 1997 論文集 Vol.9 No.-

조정식 Mg₁-χFe₂+χO₄(이하 Mg계)에서 x를 0.0, 0.025, 0.1, 0.2로 변화시키고, 소결온도를 1100°C~1250°C로 50°C간격으로 변화시켰다. 그 결과, NTC 서미스터의 특성을 잘 나타내었고, 저항온도계수 α는 Mg계일 때 -1.6%/°C로 높은 값을 나타내었고, B정수는 1500 [K]에서 2920 [K]의 범위를 나타내었다. 본 조성의 실험결과로써 Mn-Ni-Co계 서미스터를 Mg-Fe 산화물계 NTC 서미스터로 대체가 가능함을 확인할 수 있었다. Mg_{1-x}Fe_{2+x}O₄was prepared by sintering at from 1100℃ to 1250℃ with 50 C intervals, while x was varied from 0.0 to 0.025. 0.1, and 0.2. The results showed the typical properties of NTC(Negative Temperature Coefficient) thermistor. The best temperature coefficient of resistance, α was -1.6%/℃ in the Mg-based sample at 25 C. Thermistor parameter, B was in the range of 1500 [K]∼2920 [K]. As a result, the possibility that Mn-Ni-Co based thermistor could be substituted by the composition used in this study was confirmed.

中小都市의 成長要因과 特性에 관한 實證的 考察

정영동,오재화,김우혁,송승헌 朝鮮大學校 建設技術硏究所 2000 建設技術硏究 Vol.20 No.1

The study is concerned with all small and medium size cities. Study on the major purpose is to identify the domanial factors and their change for the growth of small and medium size cities through the analysis of correlation with growth rate. It could be done by case study of growth trends of all existing small and medium size cities for analysis period. The analysis results are summarized as follow : 1. Inevitably, the classification standards of the small and medium sized level in an urban hierarchy may vary among countries, depending on their pattern of urban settlement, level of development, and economic structure, population density, etc. But, the most convenient and frequently used criterion for identifying small and medium sized cities is relative population size because the city is proportional to the functional complexity. 2. The major factors affecting growth of small and medium size cities are POP, FIN, HIS, i.e., in 1986's. and the most dominant factor among them is POP, and The major factors affecting growth of small and medium sized cities are HIS, SAC, ASS, i.e., in 1996's, and the most dominant factor is HIS. 4. As the result, in small and medium size cities three variables, i.e., POP, HIS, SAC-are selected as the general factors concerned with urban population growth.

우리나라 파생상품 회계처리 기준에 관한 연구 : 기업회계기준에 관한 해석 [53-70]을 중심으로

鄭宇城,吳賢美 부산 외국어 대학교 2000 外大論叢 Vol.20 No.1

Concern has grown about the accounting and disclosure requirements for derivatives and hedging activities as the extent of use and the complexity of derivatives and hedging activities have rapidly increased in recent years. Changes in global financial markets and related financial innovations have led to the development of new derivatives used to manage exposures to risk, including interest rate, foreign exchange, price, and credit risks. So we korea built provision for derivatives and hedging, interpretation [53-70] in 1998. This paper evaluated interpretation for the Accounting Standard [53-70]. That interpretation is the latest accounting standard for derivatives Instruments in korea, and based on Fianacial Accounting stadards Board Statement No. 133(Accounting for derivatives Instruments and for Hedging Activities). Interpretation [53-70] is evaluated as follows, First, Derivative instruments represent rights or obligations that meet the definitions of assets or liabilities and should be reported in financial statements. Second, Derivative instruments should be measured at fair value, and adjust-ments to the carrying amounts of hedged items should reflect changes in their fair value that are attributable to the risk being hedged and that arise while the hedge is in effect. Third, Only items that are assets or liabilities should be reported as such in financial statements Sastly, Special accounting for items designated as being hedged should be provided only for qualifying items. Conclusionally, interpretation [53-70] contain provisions that consistent with requirements about accounting rules for derivatives and hedging.

간의 배아성 육종 -부분적으로 연골육종성 분화를 보인 1예 보고-

정우회,임현이,김호근,박찬일,오기근,최승훈 대한병리학회 1992 Journal of Pathology and Translational Medicine Vol.26 No.5

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.