부산·울산·경남지역 직업병 감시체계

김정일,김병권,김정원,채창호,이철호,강동묵,김지홍,김진하,김영욱,이영하,이지호,김정호,윤형렬,유철인,정백근,장태원,김운규,윤동영,강진욱,김종은,안진홍,이동준,장준호,이광영,송혜란,최영희,이용환,조병만,최홍렬,고상백,김은아,이유진,홍영습,정갑열,김정만,김준연 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

Objective: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases Methods: l l hospital participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted. Results: Between April 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. most of the HAVS cases came from shipbuilding, and 172 of them (92.7%) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9%). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6%) and 4 (12.1%) cases of occupational asthma, the agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10(58.8%) of the cases were diagnosed as squamous cell carcinoma and 5(29.4%) as adenoma. Conclusion: This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.

경도인지장애(Mild Cognitive Impairment)에서 단축형 Samsung Dementia Questionnaire(S-SDQ)의 임상적 유용성

윤지혜,김지혜,안인숙,정재원,송미선,김도관 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

Objuctives : Clinical utility of the Short Form of the Samsung Dementia Questionnaire (S-SDQ) as a screening instrument for Mild Cognitive Impairment (MCI). Methods : Three groups (n=27, Subjective Memory Impairment (SMI); n=41 MCI; n=79, Early Alzheimer's Di-sease(AD)) recruited from memory clinic were administered a battery of neuropsychological tests including S-SDQ and Korean version-Mini Mental State Examination (K.-MMSE). Results : S-SDQ, unlike the K-MMSE, had no association with the age and education ofthe subjects. Scores of S-SDQ was found to correlate (r=-.496) with scores of K-MMSE. Result of Receiver Operating Characteristic (ROC) analysis revealed that S-SDQ discriminated between the SMI and the MCI groups. Conclusion : S-SDQ may be a solution to the problem of contamination by education and age which affect traditional Cognitive screening instruments like K-MMSE, and it may be a useful tool for screening MCI.

보육시설 교사를 대상으로 하는 환경교육 프로그램의 개발

안지연,윤재웅,안옥희 영남대학교 지역발전연구소 1999 새마을지역개발연구 Vol.25 No.-

It is very important for preschool child to environment education in child care and education institution. However only few studies concerned to concrete education program. Therefore this study was environment education program for teacher in child care and education institution. Environment education program were consist of four steps; general idea of environment education, component abstract of environment education program for child, give motivation with development to environment education program, application of environment education program.

구치의 1급, 2급 와동에 은 아말감, 구치용 복합레진, 복합레진 인레이로 수복시 치아의 파절저항성

안연실,김미자,이광원,손호현 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

The purpose of this study was to evaluate the fracture resistance of the marginal ridge of posterior teeth with class Ⅰ & Ⅱ silver amalgam, posterior composite, and composite resin inlay. The seventy-two extracted caries free human upper premolars were divided into six groups. Class Ⅰ and Class Ⅱ cavities were prepared and filled with amalgam, light curing composite resin, and resin inlay. Fracture strength was measured at the marginal ridge with "Instron". The results were as follows ; 1. Class Ⅰ restorations were stronger than Class Ⅱ in amalgam and composite resin filled group(P<0.05). There was no statistically significant difference in strength between Class Ⅰ resin inlay and Class Ⅰ resin inlay. 2. In the Class Ⅰ and the Class Ⅱ restorations, the best fracture resistance obtained in resin inlay, followed by composite resin, amalgam(P<0.05). In the Class Ⅰ restorations, result was the same but had no significant difference. 3. Class Ⅰ composite resin and Class Ⅰ resin inlay were stronger than Class Ⅱ amalgam(P<0.05). 4. In the Class Ⅰ restorations, when the marginal ridge was fractured, only enamel or enamel/material were involved. In the Class Ⅱ composite resin and Class Ⅱ resin inlay, enamel/material or only material were involved. In the Class Ⅱ amalgam, only material was fracture.

기계적합화법으로 제조된 TiNi 분말의 방전플라즈마 소결에 관한 연구

김윤호,강지훈,김지순,안인섭,권영순 울산대학교 1999 공학연구논문집 Vol.30 No.2

기계적합금화법(MA)에 의해 제조된 TiNi 분말을 사용하여 방전플라즈마 소결법(SPS)으로 소결체를 제조하고 치밀화 거동을 조사하기 위하여 미세조직의 관찰 및 상분석을 행하였다. SPS법으로 소결체를 제조한 결과, 통상적인 소결법으로 소결체를 제조하였을 때 보다, 낮은 온도와 짧은 시간의 유지시간에서 이론 밀도의 99% 가까운 소결체 밀도를 얻을 수 있었고, 소결체의 상은 B2구조의 cubic과 2차상으로 Ti₂Ni가 존재함을 확인하였다. Mechanically-alloyed TiNi powders were densified by Spark-Plasma Sintering(SPS) method. The densififcation behavior was investigated throgh the microstructural observation, the phase analysis and the measurement of change in devsity, linear shrinkage and densification rate as a function of temperature. Sintered body with close to 99% relative density was obtained at lower sintering temperature for shorter holding time in comparison to the conventional sintering methods. TiNi with B2 structure was confirmed as the major phase and Ti₂Ni as the second phase.

대전 도덕봉과 백운봉의 산림군락 분류

김효정,이미정,지윤의,안승만,이규석,송호경 한국환경생물학회 2002 환경생물 : 환경생물학회지 Vol.20 No.3

본 연구는 계룡산국립공원의 지류인 도덕봉과 백운봉의 산림식생을 대상으로 식물사회학적 방법에 의해 산림군락을 분류하고 이 지역의 식생 현황 파악과 국립공원관리에 필요한 기초자료를 제공하고자 하였다. 식물사회학적 방법으로 89개 조사구를 분석한 결과, 신갈나무군락, 졸 참나무군락, 굴 참나무군락, 소나무군락, 서어나무군락, 리기다소나무-곰솔군락으로 구분되었다. 신갈나무군락은 해발고가 가장 높고 경사가 급한 지역에 분포하였으며,졸참나무군락은 해발고가 비교적 낮고 경사가 급한 지역에 분포하였다. 그리고 굴참나무군락은 신갈나무군락에 비해 해발고가 낮은 남사면의 건조한 지역에 분포하고 있었다. 소나무군락은 해발고가 비교적 높고 폭이 좁은 건조한 능선 부위에 분포하고 있으며, 서어나무군락은 주로 남사면 계곡부의 중부에 분포하고 있었 다. 그리고 리기다-곰솔군락은 조림군락이다. This study was carried out to classify forest vegetation community of Dodeokbong and Baekwunbong in Gyeryongsan. Employing the releve method of Dierssen, 89 plots were sampled. Forest community was classified into Quercus mongolica community, Quercus serrata community, Quercus variabilis community, Pinus densiflora community, Carpinus laxiflora community, and Pinus rigida-Pinus thunbergii community. Quercus mongolica community was found in high altitude and steep area, Quercus serrata community in relatively low altitude and steep slope area, and Quercus variabilis in southern arid and low area compared with Quercus mongolica community. Pinus densiflora community is present in relatively high altitude and narrow arid ridge area. And, Carpinus laxiflora community is mainly distributed in southern valley area. Pinus rigida-Pinus thunbergii community is planted community.

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

대한방사선종양학회지 게재 논문의 통계적 오류 현황

박희철(Hee Chul Park),최두호(Doo Ho Choi),안성복(Song-Vogue Ahn),강진오(Jin Oh Kang),김은석(Eun-Seog Kim),박원(Won Park),안승도(Seung Do Ahn),양대식(Dae Sik Yang),윤형근(Hyong Geun Yun),정은지(Eun Ji Chung),지의규(Eui Kyu Chie),표홍렬( 대한방사선종양학회 2008 Radiation Oncology Journal Vol.26 No.4

목 적: 본 연구는 대한방사선종양학회지 게재 논문의 통계 오류 현황을 파악하고 이에 근거한 문제 제기를 통해 학회지의 학술적 발전에 기여하고자 하였다. 대상 및 방법: 2006∼2007년 사이에 대한방사선종양학회지에 게재된 총 77편의 논문을 연구 대상으로 하였다. 각각의 논문에 적용된 통계 방법론의 적정성 평가는 통계점검표를 활용하였다. 통계점검표에는 연구의 종류, 통계기법의 사용 범위, 각 논문에 적용된 통계 기법의 종류, 통계적 기법 적용의 타당성 항목이 포함되었다. 통계 오류는 ‘생략의 잘못’과 ‘시행의 잘못’ 항목으로 나누었다. 한 논문에서 서로 다른 항목이 여러 가지 관찰된 경우 각각 횟수로 측정하였다. 같은 항목이 2회 이상 측정된 경우 1회로 횟수를 측정하였다. 통계 전문가가 개별 논문을 대상으로 통계점검표를 작성하였다. 일차 평가자가 방사선종양학 전문가가 아닌 것에서 올 수 있는 평가 오류가 있을 수 있으므로 개별 통계점검표는 간행위원회에서 한 차례 더 세부 점검을 하였다. 작성된 통계점검표의 통계 분석은 SAS (version 9.0, SAS Institute, NC, USA) 소프트웨어를 이용하였고 빈도분석을 시행하여 각 항목의 빈도와 백분율을 산출하였다. 결 과: 총 77편 중 원문을 다운로드 할 수 없었던 4편을 제외한 73편의 게재 논문을 대상으로 평가하였다. 증례보고는 5편, 원저 논문은 68편이었다. 대상 논문 중 46편의 논문에서 통계적 추론을 사용하였고, 16편의 논문에서 단순한 기술통계를 사용했으며, 11편의 논문에서는 통계적 기법을 사용하지 않았다. 추론통계를 사용한 46편의논문에서 사용된 추론통계의 횟수는 각각 분할표분석 17회(37.0%), 비교통계분석 23회(50.0%), 회귀분석 7회(15.2%), 상관분석 5회(10.9%), 생존분석이 27회(58.7%)였다. 통계 기법을 활용하여 연구 결과를 분석할 때 통계적용의 오류가 없는 논문은 19%였다. ‘생략의 잘못’은 34편(50.0%)의 논문에서 총 50회 관찰되었다. ‘시행의 잘못’은 35편(51.5%)의 논문에서 총 47회 관찰되었다. ‘생략의 잘못’과 ‘시행의 잘못’이 모두 발견된 논문은 21편 (30.9%)이었다.결 론: 대한방사선종양학회지에 게재된 논문에서 통계 분석 과정의 다양한 영역에 걸쳐 크고 작은 통계적 오류가 있음을 확인하였다. 향후 대한방사선종양학회지 투고 논문의 심사 과정에서 통계 오류에 관한 적절한 심사를 추가하는 것이 필요하다고 판단된다. Purpose: To improve the quality of the statistical analysis of papers published in the Journal of the Korean Society for Therapeutic Radiology and Oncology (JKOSTRO) by evaluating commonly encountered errors. Materials and Methods: Papers published in the JKOSTRO from January 2006 to December 2007 were reviewed for methodological and statistical validity using a modified version of Ahn’s checklist. A statistician reviewed individual papers and evaluated the list items in the checklist for each paper. To avoid the potential assessment error by the statistician who lacks expertise in the field of radiation oncology; the editorial board of the JKOSTRO reviewed each checklist for individual articles. A frequency analysis of the list items was performed using SAS (version 9.0, SAS Institute, NC, USA) software. Results: A total of 73 papers including 5 case reports and 68 original articles were reviewed. Inferential statistics was used in 46 papers. The most commonly adopted statistical methodology was a survival analysis (58.7%). Only 19% of papers were free of statistical errors. Errors of omission were encountered in 34 (50.0%) papers. Errors of commission were encountered in 35 (51.5%) papers. Twenty-one papers (30.9%) had both errors of omission and commission. Conclusion: A variety of statistical errors were encountered in papers published in the JKOSTRO. The current study suggests that a more thorough review of the statistical analysis is needed for manuscripts submitted in the JKOSTRO.

Uterotrophic and Hershberger Assay for Butyl ρ-Hydroxybenzoic Acid

Ji Yun Ahn,Sung Ran Kim,Tae Youl Ha,Sung Su Kim,Chan Kyu Han 한국독성학회 2005 Toxicological Research Vol.21 No.2

Butyl ρ-hydroxybenzoic acid (butyl paraben, BP) is a homologous series of parabens and is widely used as a preservative in cosmetic and pharmaceutical products. The purpose of this study was to investigate the estrogenic/antiandrogenic activities of BP in animals. For that, we performed an uterotrophic assay and a Hershberger assay in rats. In uterotrophic assay, BP was administered subcutaneously to immature female SD rats (18 days old) for 3 consecutive days. The wet and dry uterus weights were significantly increased in the groups treated with BP in dosedependent manner. In case of Hershberger assay, BP significantly reduced the weight of seminal vesicle of castrated rats. And other accessory organ/glands - prostate, Cowper’s glands, bulbocavernosus muscle and glans penis were also slightly decreased. The results of this study suggested that BP showed estrogenic and anti-androgenic activities in vivo.

Protective Effect of Ginseng against Endocrine Disrupting Toxicity Induced by Butyl p-Hydroxybenzoic Acid

Ji-Yun Ahn,Tae-Youl Ha,Sung-Ran Kim,Kyung-Sun Kang,Chan-Kyu Han 한국식품과학회 2003 Food Science and Biotechnology Vol.12 No.6