인터뷰 - 김지혜 롯데칠성음료(주) 디자인팀 디자이너

김지혜,Kim, Ji-Hye (사)한국포장협회 2010 包裝界 Vol.210 No.-

지식경제부와 한국디자인진흥원은 대한민국 디자인 산업을 이끌어갈 우수한 신예 디자이너 발굴의 장이자, 국내 산업 디자인의 미래를 조망하는 "대한민국디자인전람회" 수상작을 발표했다. 대한민국 디자인계를 이끄는 학계 산업계의 초대 추천 디자이너 542명을 배출한 이 전람회는 1995년부터 집계된 출품 수만 2만5천여 점에 달하는 국내 최대 최고 규모의 공모전이다. 이번 전람회에서는 롯데칠성 디자인팀의 김지혜 씨가 바쁜 현대인들에게 안전하고 건강한 생활 식습관을 제안한 "요리하는 즐거움, 건강한 라이프스타일을 위한 패키지디자인연구"로 국무총리상을 수상하게 됐다. 김지혜 디자이너에게 작품 소개 및 패키지디자인에 대한 견해를 들어보았다.

The Stress-Reducing Effects of Forest Healing Activities in Maladjusted Military Force Members

김지혜,신창섭,김지혜,김도형,김윤수,이현채 인간식물환경학회 2020 인간식물환경학회지 Vol.23 No.3

Background and objective: In the Republic of Korea, military service is mandatory. Some of new recruits have the stress from the special environment, which could cause psychological maladjustment. The military forces have operated education programs such as green camp and healing camp. The study was conducted to investigate changes in psychological and physiological stress by conducting forest healing activities along with plant scent treatment for soldiers participating in a green camp. Methods: A total of 52 soldiers were participated including maladjustment soldiers and those recommended by their military units to protect the unfit soldiers who participated in forest healing activities in the green camp. The programs that were certified by the Korea Forest Service between 2014 and 2019, and were applied for stress reduction and relaxation training were classified into stress-coping programs and forest experience programs. Post-hoc surveys and cortisol measurements were carried out. Results: Green camp soldiers experience and differences in the level of stress responses were found to be very statistically significant between the treatment and control groups. The techniques for coping with stress were not significantly different in the control group, and the treatment group showed statistically significant results. In addition, the results of analyzing changes in the concentration of cortisol and measuring physiological stress were very statistically significant in forest healing activities at 4 p.m. Conclusion: Once green camp soldiers face stressful situations, forest healing programs using forest plant scents for green camp soldiers can have positive responses and forest healing activities can reduce psychological and physiological stress responses, improving maladjustment behaviors caused by stress and positively affecting the reduction of cortisol.

In Vivo Angiogenic Capacity of Stem Cells from Human Exfoliated Deciduous Teeth with Human Umbilical Vein Endothelial Cells

김지혜,남현,김지혜,김재원,편희장,이재천,이진 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.11

Dental pulp is a highly vascularized tissue requiring ade-quate blood supply for successful regeneration. In this study, we investigated the functional role of stem cells from human exfoliated deciduous teeth (SHEDs) as a perivascular source for in vivo formation of vessel-like structures. Primarily isolated SHEDs showed mesenchymal stem cell (MSC)-like characteristics including the expression of surface antigens and in vitro osteogenic and adipogenic differentiation potentials. Moreover, SHEDs were positive for NG2, -smooth muscle actin (SMA), platelet-derived growth factor receptor beta (PDGFR), and CD146 as pericyte markers. To prove feasibility of SHEDs as perivascular source, SHEDs were transplanted into immunodeficient mouse using Matrigel with or without human umbilical vein endothelial cells (HUVECs). Transplantation of SHEDs alone or HUVECs alone resulted in no formation of vessel-like structures with enough red blood cells. However, when SHEDs and HUVECs were transplanted together, extensive vessel-like structures were formed. The presence of murine erythrocytes within lumens sug-gested the formation of anastomoses between newly formed vessel-like structures in Matrigel plug and the host circulatory system. To understand underlying mechanisms of in vivo angiogenesis, the expression of angiogenic cytokine and chemokine, their receptors, and MMPs was compared between SHEDs and HUVECs. SHEDs showed higher expression of VEGF, SDF-1, and PDGFRthan HUVECs. On the contrary, HUVECs showed higher ex-pression of VEGF receptors, CXCR4, and PDGF-BB than SHEDs. This differential expression pattern suggested reciprocal interactions between SHEDs and HUVECs and their involvement during in vivo angiogenesis. In conclusion, SHEDs could be a feasible source of perivascular cells for in vivo angiogenesis.

대학생의 부모애착과 대학생활 적응 간의 관계에서 자기수용의 매개효과

김지혜,김해란 한국청소년시설환경학회 2020 청소년시설환경 Vol.18 No.2

The purpose of this study is to verify the mediating effect of unconditional self-acceptance in the relationship between college students' parent attachment and adaptation to college life. The results of this study if as follows: First, there was no difference in gender and residence type regarding adaptation to college life. Meanwhile, there was a statistically significant difference in students' grades. But there was no statistically significant difference in the Scheffes' verification. Second, college students' parent attachment and adaptation to college life showed a significant positive correlation. Third, it was verified that unconditional self-acceptance carries out partial mediation when it comes to the relation between college students' parent attachment and adaptation to college life. The results of this study lie in the discovery of the fact that unconditional self-acceptance could be used for an important variable in the relationship between college students' parent attachment and adaptation to college life. 본 연구는 대학생의 부모애착과 대학생활 적응 간의 관계에서 자기수용의 매개효과를 검증하고자 하는데 그 목적이 있다. 이를 위해 본 연구는 수도권 소재 4년제 대학의 재학생 283명을 대상으로 부모애착, 대학생활 적응, 자기수용 검사를 실시하였다. 모든 분석은 SPSS 19.0 프로그램을 사용하였으며 분석과정은 다음과 같다. 첫째, 연구 대상자의 인구통계학적 특성을 알아보고자 빈도와 백분율을 산출하였다. 둘째, 연구에서 사용한 각 척도의 신뢰도를 알아보기 위해 척도별 및 하위요인별 Cornbach's α 계수를 산출하였다. 셋째, 연구대상자의 인구사회학적 특성에 따른 대학생활 적응의 차이를 알아보기 위해 t-test와 일원배치분산분석을 실시하였다. 다섯째, 대학생의 부모애착, 자기수용, 대학생활 적응의 관계를 알아보기 위해 Pearson 상관관계분석을 실시하였다. 여섯째, 대학생의 부모애착과 대학생활 적응 간의 관계에서 자기수용의 매개효과를 알아보기 위해 Baron과 Kenny가 제안한 절차에 따라 매개효과분석을 실시하였으며 매개효과의 유의성을 검증하기 위해 sobel test를 실시하였다. 본 연구의 주요 결과를 요약하면 다음과 같다. 첫째, 성별 및 거주형태에 따른 대학생활 적응의 차이는 통계적으로 유의미하지 않았다. 한편, 학년에 따른 대학생활 적응의 차이는 통계적으로 의미있는 차이를 보였으나 Scheffe의 사후검증에서 유의미한 차이가 나타나지 않았다. 둘째, 대학생의 부모애착과 자기수용은 대학생활 적응과 유의미한 정적상관이 나타났다. 셋째, 자기수용은 부모애착과 대학생활 적응 간의 관계를 부분매개하는 것으로 나타났으며 유의성 검증 결과 또한 통계적으로 유의한 것으로 나타났다. 이에 본 연구는 대학생의 부모애착과 대학생활 적응 간의 관계에서 자기수용의 매개효과를 확인하였으며 자기수용이 대학생의 부모애착과 대학생활 적응 간의 관계에서 중요한 변수로 활용될 수 있음을 밝힌 점에서 연구의 의의가 있다.

Comparison of cardiovascular event predictability between the 2009 and 2021 Chronic Kidney Disease Epidemiology Collaboration equations in a Korean chronic kidney disease cohort: the KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease

김지혜,강민정,강은정,류현진,정유진,김자연,박수경,정종철,유태현,김예니,김용철,한승석,이하정,오국환 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.6

Background: The 2009 Chronic Kidney Disease Epidemiology Collaboration creatinine-based estimated glomerular filtration rate (eGFRcr) equation contains a race component that is not based on biology and may cause a bias in results. Therefore, the 2021 eGFRcr and creatinine-cystatin C–based eGFR (eGFRcr-cysC) equations were developed with no consideration of race. This study compared the cardiovascular event (CVE) and all-cause mortality and CVE combined predictability among the three eGFR equations in Korean chronic kidney disease (CKD) patients. Methods: This study included 2,207 patients from the KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease. Receiver operating characteristic (ROC) and net reclassification improvement (NRI) index were used to compare the predictability of the study outcomes according to the 2009 eGFRcr, 2021 eGFRcr, and 2021 eGFRcr-cysC equations. Results: The overall prevalence of CVE and all-cause mortality were 9% and 7%, respectively. There was no difference in area under the curve of ROC for CVE and mortality and CVE combined among all three equations. Compared to the 2009 eGFRcr, both the 2021 eGFRcr (NRI, 0.013; 95% confidence interval [CI], – 0.002 to 0.028) and the eGFRcr-cysC (NRI, –0.001; 95% CI, –0.031 to 0.029) equations did not show improved CVE predictability. Similar findings were observed for mortality and CVE combined predictability with both the 2021 eGFRcr (NRI, –0.019; 95% CI, –0.039–0.000) and the eGFRcr-cysC (NRI, –0.002; 95% CI, –0.023 to 0.018). Conclusion: The 2009 eGFRcr equation was not inferior to either the 2021 eGFRcr or eGFRcr-cysC equation in predicting CVE and the composite of mortality and CVE in Korean CKD patients.

잘 차린 밥상에 양념 한가지

김지혜 한국언론학회 1994 저널리즘비평 Vol.14 No.1

다문화 청소년의 문화적응스트레스가 우울과 자아존중감을 매개로 학교적응에 미치는 영향

김지혜 한국청소년시설환경학회 2019 청소년시설환경 Vol.17 No.3

The purpose of this study is to investigate the effects of acculturative stress on the school adjustment mediated by depression and self-esteem. Data were obtained from the Multicultural Adolescents Panel Study(MAPS). Structural equation modeling was employed for statistical analyses. On the results of this study, acculturative stress showed significantly positive influence on the depression, however, negative influence on the self-esteem. Depression significantly negative influence on the school adjustment and self-esteem significantly positive influence on the school adjustment. Also, acculturative stress showed negative influence on the school adjustment. On the analysis results of mediation effect, depression and self-esteem are partially mediating the influence of acculturative stress on the school adjustment. Based on these results, this study suggested the method to increase the school adjustment of multicultural adolescents. 1. 연구배경 및 목적우리나라의 다문화가정은 매 년 증가하고 있으며, 다문화가정의 청소년기 자녀도 매 년 증가하고 있다. 다문화 청소년은 다양한 요인으로 인해 학업생활에 어려움을 겪으며, 이러한 어려움은 학업중단으로 이어진다. 교육부(2019)의 현황자료에 의하면, 비다문화 청소년에 비해 학업중단율이 높은 것으로 나타났으며, 특히 중학생의 경우 다문화청소년과 비다문화 청소년의 학업중단율 차이가 크게 나타났다. 따라서 시기에 학교적응에 영향을 미치는 요인들을 확인하여 개입의 방향을 결정할 필요가 있다. 본 연구는 다문화청소년의 문화적응스트레스가 개인 내적 요인 중 위험요인인 우울과 보호요인인 자아존중감을 매개로 학교적응에 미치는 영향을 확인함으로써 청소년기에 다문화청소년의 학교적응을 높이기 위한 정책적, 실천적 함의를 제공하고자 하였다. 2. 연구방법 및 범위본 연구에서는 다문화청소년의 문화적응스트레스가 우울과 자아존중감을 매개로 학교적응에 미치는 영향을 분석하기 위해 한국청소년정책연구원에서 수행하고 있는 ‘다문화 청소년 패널조사(MAPS)’의 6차년도 자료인 중학교 3학년 1,329명의 자료를 분석에 사용하였다. 구조방정식 모형을 사용하였으며 주요 변수에 대한 기술통계를 실시한 후, 측정의 적합도를 검토하기 위해 측정모형을 추정하고, 측정모형을 활용하여 변수 간의 예측 관계를 검증하기 위하여 구조모형 분석을 실시하였다. 또한 매개변수의 영향을 확인하기 위해 총효과를 직접효과와 간접효과로 분해하여 각 경로별 관계와 유의도를 살펴보았으며, 소벨검증을 통해 매개효과의 유의도를 검증하였다. 3. 연구결과본 연구의 결과를 정리하면 다음과 같다. 첫째, 다문화청소년의 문화적응스트레스가 학교적응에 미치는 영향을 살펴보면, 문화적응스트레스가 높은 다문화청소년은 학교적응 정도가 낮은 것으로 나타났다. 둘째, 다문화청소년의 문화적응스트레스가 우울과 자아존중감에 미치는 영향을 살펴보면, 문화적응스트레스가 높으면 우울 수준이 높고, 자아존중감은 낮은 것으로 나타났다. 셋째, 다문화청소년의 우울과 자아존중감이 학교적응에 미치는 영향을 살펴보면, 우울이 증가할수록 학교적응은 낮아지며, 자아자존중감이 증가할수록 학교적응은 높아지는 것으로 나타났다. 마지막으로 다문화청소년의 문화적응스트레스가 학교적응에 미치는 영향에서 우울과 자아존중감의 매개효과를 살펴본 결과, 문화적응스트레스가 우울을 매개로 학교적응에 미치는 경로와 자아존중감을 매개로 학교적응에 미치는 경로 모두에서 매개효과가 통계적으로 유의하였다. 즉, 다문화청소년의 문화적응스트레스가 높을수록 우울이 증가하며, 우울이 증가하면 학교적응은 감소한다. 반면에, 문화적응스트레스가 높을수록 자아존중감은 감소하며, 낮은 자아존중감은 학교적응을 감소시킨다.

[③ 코멘트_공예를 말한다] 공예 교육, 융합과 통섭으로

김지혜 에이엠아트 2023 Art in culture Vol.24 No.10

미세먼지에 대한 소셜 미디어 건강정보 사회적 시청이 질병예방행위의도에 미치는 영향: 건강신념모델의 매개모형 적용을 중심으로

김지혜,조재희 한국방송학회 2019 한국방송학보 Vol.33 No.4

This study aimed at examining how individuals’ social viewing of information about fine dust on social media would impact their perception about find dust as well as behavioral intentions of disease prevention. For this examination, this research investigated how subᐨdimensions of social viewing(‘passive acceptance of information’ and ‘active sharing of information’) would affect both main variables (perceived severity and susceptibility of disease caused by fine dust, perceived benefit and barrier of prevention behaviors) from health belief model and behavioral intention of disease prevention. According to research findings, while people’s positive acceptance of information significantly and positively affected perceived ‘severity’ and ‘susceptibility’ of disease caused by fine dust, their active sharing of information negatively and significantly influenced perceived ‘severity’ of potential disease and ‘barriers’ of prevention behaviors. Moreover, only perceived severity of disease caused by fine dust significantly increased people’s intention to conduct prevention behaviors.

Micro BCR/ABL 재배열을 가진 비전형적 만성골수성백혈병 1예

김지혜,이원목,류남희,전동석,김재룡,권기영,하정숙 대한혈액학회 2008 Blood Research Vol.43 No.3

Microtype BCR/ABL rearrangement is extremely rare and has been known to be associated with neutrophilic chronic myeloid leukemia (N-CML). However, there is more to be understood regarding this phenotype. We report a case of atypical CML that exhibited micro BCR/ABL rearrangement with predominant thrombocytosis. Our patient showed thrombocytosis (1,464×109/L) and megakaryocytosis in the peripheral blood and bone marrow. However, neither leukocytosis nor neutrophilia was observed (white blood cells (WBC), 5.02×109/L neutrophils, 45%). Bone marrow aspirate revealed increased cellularity: 12% basophils, 6% eosinophils, and 9% blasts. The 46,XX,t(9;22)(q34;q11.2),i(17q) chromosome complement was observed in 4 of 20 metaphase cells, and standard BCR/ABL fusion signals were observed in 10% of interphase cells on fluorescence in situ-hybridization (FISH) analysis. Reverse transcriptase- polymerase chain reaction (RT-PCR) was used to acquire the BCR/ABL fusion transcript, the identity of which was confirmed via sequence analysis. Hematologic remission was achieved 2 months after imatinib therapy initiation, and molecular remission was achieved 2 months after hematologic remission. The patient is currently undergoing regular follow-up visits and is in good health. However, further long-term follow up is warranted. The incorporation of imatinib into therapeutic strategies may be further established through the study of more cases of micro BCR/ABL. (Korean J Hematol 2008;43:184-189.)