http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
들잔디 성숙종자로부터 캘러스배양 및 식물체 재분화에 미치는 몇 가지 요인의 영향
이상훈,김범수,원성혜,조진기,김기용,박근제,성병렬,이효신,이병현 Plant molecular biology and biotechnology research 2004 Plant molecular biology and biotechnology research Vol.2004 No.-
In an effort to optimize tissue culture responses of zoysiagrass (Zoysia japonica Steud.) for genetic transformation, factors affecting callus induction and plant regeneration were investigated. MS medium containing 3 ㎎/L 2,4-D was optimal for embryogenic callus induction from mature seed. The plant regeneration frequency of 73.3% was observed when embryogenic calli induced in this medium were transferred to N6 medium supplemented with 0.1 ㎎/L 2,4-D and 5 ㎎/L BA. Among several basic media, MS and N6 medium were optimal for callus induction and plant regeneration, respectively. Regenerated plants were grown normally when shoots transplanted to the soil. A rapid and efficient plant regeneration system established in this study will be useful for molecular breeding of turfgrass through genetic transformation.
서영범,김성욱,장재식,강혁주,이중현,윤병구,김욱년,이광헌,이구,유석동,양창헌,이정호,이영현,이창우,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-
자가면역성 간염은 대개 만성 경과를 가지며, 혈중 자가면역항체와 혈청 글로불린치의 상승, 그리고 조직학적으로 괴사 염증성 변화를 특징으로 하는 질환으로 아직 정확한 병인이 밝혀져 있지 않은 상태이다. 발병연령은 대개 젊은 영자(15-25세)에서 호발한다. 이 질환은 급성 간염의 임상경과를 보일 수 있으나, 심한 급성 간염이나 전격성 간염으로도 나타날 수 있는데, 이 경우 아주 나쁜 예후를 보인다고 한다. 치료는 자가면역성 간염 임상 경과의 다양성이나 병인, 병리기전의 불확실성에도 불구하고 대개 steroid 치료에 반응하는 것으로 알려져 있으며 대개 80%의 관해율을 나타내며 궁극적으로 간경변으로의 진행을 막을 수 있는 것으로 보인다. 저자들은 58세 남자에서 발생한 급성의 경과를 가지고 심한 황달을 동반한 자가면역성 간염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. The age of onset of AIH show a peak between the age of 15 and 25 years. AIH can develop and be manifested as acute hepatitis, but severe form of acute hepatitis or fulminant hepatic failure has a poor prognosis. Although AIH is likely to progress from chronic active hepatitis to cirrhosis, steroid therapy can control the disease activity, prolong survival, improve the quality of life , and defer liver transplantation. In the present report we describe a 58-year-old man who admitted because of progressive jaundice and fatigue. He was diagnosed with AIH from laboratory test result showing positivity for antinuclear antibodies, anti-smooth muscle antibodies, and negativity for hepatitis viral markers and from liver biopsy. Steroid therapy, oral administration of prednisolone, was effective in improving the liver function test. Following liver biopsy 6 months after onset shows markedly improved necroinflammatory activity.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
편평세포폐암에서 p53 돌연변이의 발현과 TNM 병기와의 상관관계
이상숙,한승범,전영준 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4
Primary lung cancer is now recognized as a major cause of cancer death in Korea as well as the whole world. Non-small-cell lung cancers(NSCLC) comprise about 75% of lung cancer and squamous cell carcinoma is the most common type in Korea. Mutations of p53 gene are common in variety of human cancers, including lung cancer. The p53 gene appears to inhibit the proliferation of cells from the G1 to the S phase of cell cycle and is able to suppress the transformations of cells by other oncogenes, to inhibit the growth of malignant cells in vitro and suppress the tumorigenic phenotype of transformed cells. Alteration or inactivation of p53 by mutation, or by its interactions with oncogene products of DNA tumor viruses, can lead to cancer. These mutations seems to be the most common genetic changes in human cancers. p53 gene mutation is known to be a poor prognostic marker in breast cancer and has significant association with lymph node involvement. But in human lung cancer the association of p53 mutations and TNM stages are controversial. Immunohistochemical staining can detect only mutant p53 protein bacause of markedly prolonged half life of mutant p53 protein. We performed the immunohistoschemical staining on 48 surgically resected and 10 bronchoscopically biopsized specimens of primary squamous cell carcinoma of the lung with monoclonal antibody(DO 7) and analyzed the relationship between the expression of p53 protein and clinical TNM stages. p53 protein was detected in 60.3% of total 58 cases. p53 protein was positive in 52.9% of stage I(17cases), 83.3% of stage Ⅱ(6 cases), 72.2% of ⅢA(18 cases), 42.9% of ⅢB(7 cases) and 50% of stage Ⅳ(10 cases) which revealed no significant correlation between p53 protein detection and stages. There was no significant correlation between p53 protien detection and No and N₁-₃as well Mo and M₁. In conclusion, we couldn't find any significant correlation between p53 protein detection and TNM stages which suggests p53 mutation is frequent in squamous cell carcinoma of the lung but play different role in progression of clinical stages.
이성범,이홍주,황성준 안성산업대학교 2002 論文集 Vol.34 No.-
This study was conducted to control the posture of implement attached to tractor, which could make important effects on the working performance and accuracy. A tool bar, should be attached to the 3-point hitch, was designed to control the posture of implement by differentiating distances between one upper link and two lower links independently and simultaneously. By using PWM control method, the hydraulic fluid quantity was controlled proportionally according to the change of duty ratio with a high speed electronic solenoid valve. Computer simulation and fundamental test were also conducted for the developed posture control system using AMESim analysis tool The results of this study could be summarized as follows : 1. According to the results of computer simulation, major design parameters such as PWM control frequency, control agin, orifice diameter, and fluid pressure were determined as 30㎐, 1.5, 1.8㎜, and 10MPa, respectively. Time constant to make 100㎜ of stroke in load direction was about 0.55 seconds. 2. The tool bar, which was consisted of hydraulic cylinders and metal guides, was fabricated and tested for the performance of over all system. 1.6 seconds of response time of the control system was needed at inclination of 22°, and the performance of the posture control system was best at 150MPa of relief pressure, 1.5 of control gain, 20㎐ of PWM control frequency, and 2.2㎜ of orifice diameter, which did not represent considerable difference in compare with the results of computer simulation.
이건범,정회민,편영식,주상윤 한국공작기계학회 1998 한국생산제조학회지 Vol.7 No.1
In order to increase the modeling power and productivity of CAD/CAM systems, demands for customization of CAD/CAM system increased. Customization of a CAM system involves making it easier to learn and use, adding new modeling features not supported in a general purpose CAM system, and providing parametric inputting mechanisms. A customization from a commercial CAM system (OMEGA) has implemented for two dimensional free curve CNC glass scribing machine of medium size company in Cheonan. A CAD technician who has no CAM experience can operate this customized CAM system satisfactorily.
Kohonen의 자율 학습 신경망칩을 위한 OTA 곱셈기와 수정된 Gilbert 곱셈기의 비교
이상범,조용범 건국대학교 1995 學術誌 Vol.39 No.2
This paper compares characteristics of OTA multiplier and the modified Gilbert multiplier for neural chips of Kohonen's SOM algorithm. To design neural chip, it is necessary to reduce the size of circuits because a massive number of imterconnectlons between neurons are used. For the comparision, the performance of two multipliers was tested by SPICE circuit simulations. OTA multiplier has approximately a half size of the modified Gilbert multiplier. OTA multiplier also has wider operation range from -4.8V to 4.8V compared with the modified Gilbert multiplier ranging from -0.5V to 0.5V. Test spice cells for OTA multiplier-based neural processor and the modified Gilbert multiplier-based neural processor were also desgined and tested for comparisons. The entire operation speed of test slice cells was that OTA multiplier - based neural processor had 27ns rising time and 55ns failing time, and the modified Gilbert multiplier-based neural processor had 53ns rising time and 60ns falling time. The proposed OTA multiplier can be used for highspeed and high integrated applications.