A Study on the appropriate herbal medicine according to Sasang constitution using EAV

Choi,Jin-Wook,Lee,Su-kyung,Hong,Suck-chull,Koh,Byung-hee INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1997 JOURNAL OF ORIENTAL MEDICINE Vol.2 No.1

1. Objective This is a basic study about the response of herbal medicine to EAV. The purpose was to investigate how the meridian of EAV responded to herbal medicine and how EAV was applied to the diagnosis of Sasang constitution. 2. Materials & Methods The subjects of this study were patients who were being treated in the Dept. of Constitutional Medicine ot Kyung-Hee Medical Center. The study examined how herbal medicine affected the maximum value and the indicator drop and how each constitution responded differently to the constitutional herb medicine. 3. Results & Conclusions 1) When comparing the maximum value and ID of the worst BAP before and after the experiment with herbal medicine, the maximum value significantly went up and the ID significantly went down in all the herbal medicines. So we confirmed that all the herbal medicines positively affected the change of the maximum value and ID. 2) The changes in the maximum value induced by herbal medicines were significantly different according to the constitution of Dokhual Jihwang Tang, and Hyangbuja Palmul Tang. Although Dokhual Jihwang Tang was soyangin's herb medicine in Sasang constitutional medicine, it raised the value of soeumin higher than that of soyangin. Hyangbuja Palmul Tang which was soeumin's herb medicine raised the value of soeumin higher than that of the other constitution. 3) The changes of ID were not significantly different in the constitution.

의료환경 변화에 대비한 의학기술부문의 교육방향

최종학,윤범철,조경진,이준협,임국환,고성진,최경호 高麗大學校 倂設 保健大學 保健科學硏究所 2003 保健科學論集 Vol.29 No.1

Under the pressure to open the service market as proposed by World Trade Organization, we can easily expect our educational systems for allied health professions will experience a lot of changes in near future. Accordingly, we compared our current educational systems for allied health professions with the foreign ones and mapped out some strategies predicting the forthcoming enormous changes. Major investigations and analysis are summed up as follows, The educational programs for allied health professions which was started in 1963 in Korea are stilled remained as 2 to 3 school years, while the systems in advanced countries have already been changed or been changing from 2 year to 4 year college levels. We can hardly find the uniform educational system or school years for the allied health professions in the world except for Korea. Fortunately, university level four-year programs for the profession was established in 1979 in Won-joo for the first time in Korea. However, there are still only few four-year programs in this country. To meet the rapidly changing needs we have faced in the health areas we should supply appropriate health personnel through various efforts. Now we would like to suggest followings, <Educational goals for the allied health professions> 1) reconfirming characteristics for the educational goals of health professions 2) extending school years for the allied health professions 3) strengthening clinical training and internship 4) expanding opportunities for the continuing education through lifelong education 5) upgrading from old-fashioned technologies to advanced technologies 6) cultivating competencies of health professionals for the global competition <Suggestions for the Development of Allied Health Professions> 1) reforming the school years of educational programs for the allied health professions to meet the global standards 2) expanding the role of junior college programs for the allied health professions through the development of intensive courses in the professions. 3) diversifying and specializing the allied health professions mainly through 4 year B.S. degree programs.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

주택연금 수익비 분석에 관한 연구

최경진(Choi, Kyung-Jin),이동화(Lee, Dong-Hwa) 한국경영교육학회 2020 경영교육연구 Vol.35 No.4

[연구목적] 주택연금은 생존 시 자신의 소유주택에 거주하면서 월지급금을 받을 수 있을 뿐 만 아니라 사망 시 주택처분가액이 대출잔액에 비해 높을 경우 그 차액에 대해 상속이 가능하다. 그러나 이러한 장점에도 불구하고 월지급금에 대한 불만족으로 주택연금의 가입률은 저조한 상황이다. 본 연구에서는 주택연금의 장점을 반영한 연령 및 주택가격별 가입자의 수익비를 산출하여 주택연금의 종합적 가치를 분석하고 관련 시사점을 제공하고자 하였다. [연구방법] 본 연구는 주택연금의 장점을 계량화하여 가입 시 주택가격 대비 월지급금, 거주안정, 유산의 현재가치를 모두 합한 총 주택연금가치의 비율을 수익비로 정의하여 2019년 기준 가입연령별 주택연금의 수익비를 산정하였다. [연구결과] 주택연금의 수익비를 산정한 결과, 모든 연령대에서 수익비가 1을 초과하는 것으로 나타나 주택연금의 사회보장적 성격이 내재되었음을 확인할 수 있었다. 또한 저 연령 가입자 일수록 수익비는 높게 나타나 저연령 가입자가 상대적으로 유리한 구조로 주택연금제도가 설계된 것을 확인할 수 있었다. [연구의 시사점] 따라서 유형의 월지급금 뿐 만 아니라 주택연금에 내재된 거주안정 및 유산의 가치 등 주택연금의 종합적인 가치를 면밀히 고려하여 합리적인 가입의사결정을 할 필요가 있다. [Purpose] Korean are reluctant to join the reverse mortgage as they are unsatisfied for the level of monthly payment even though the reverse mortgage provides various benefits. In this paper, we conduct money’s worth analysis in order to deal with reasons why they do not prefer to join reverse mortgage in Korea. [Methodology] We define the total value of reverse mortgage which includes the ratio of property value and monthly payment, the residential stability and the present value of inheritance. And then we calculate the money’s worth ratio of reverse mortgage by borrower’s age as of 2019. [Findings] Our results show that the money’s worth ratio for all ages was calculated more than 1, confirming that the characteristics of social security is inherent in the reverse mortgage. Additionally, the younger member joins the reverse mortgage, the higher money’s worth ratio are provided in our results. That is, the reverse mortgage is designed with a relatively favorable structure for younger borrowers. [Implications] Thus, peoples need to decide rationally by considering aggregate value of reverse mortgage which consists of not only monthly payment but also the residential stability and inheritance value.

심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

(±)-Camphor가 ICR 마우스 수컷의 간 cytochrome P450 효소 활성에 미치는 영향

오은경,박형건,배기현,최옥진,최은경,최창근,한진희,정태천 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.4

Effects of (±)-camphor on liver cytochrome P450 enzymes were investigated in male ICR mice. Mice were treated intraperitoneally with 0, 200, 400 and 800 mg/kg of (±) -camphor in corn oil for 3 consecutive days. Twenty four hr after the final treatment, the animals were subjected to necropsy. The activities of serum aspartate aminotransferase and serum alanine aminotransferase were slightly changed by the treatment with (±)-camphor at the doses used. Administration o(±)-camphor to mice significantly induced the hepatic activities of pentoxyresorufin O-depentylase and benzyloxyresorufin O-debenzylase and weakly induced ethoxyresorufin O-deethylase in dose-dependent manners. The present results suggested that (±)-camphor might act as a relatively specific inducer of hepatic cytochrome P450 213 in male ICR mice.

곰소만에 있어 바지락포자충, Perkinsus sp.의 출현에 관하여

박경일,최광식,최진우,PARK Kyung-Il,CHOI Kwang-Sik,CHOI Jin-Woo 한국수산과학회 1999 한국수산과학회지 Vol.32 No.3

이 연구를 통하여 바지락 대량 폐사가 발생한 전라북도 곰소만에 서식하고 있는 패류, 바지락, R. philipinarium, 굴 C. gigas, 피조개, S. broughtonii, 피뿔고둥, R. venosa, 등을 대상으로 바지락포자충, Perkinsus sp. 감염 여부 및 정량적인 분석을 수행하였다. 바지락포자충의 감염 진단은 Ray(1952)의 방법에 따라 혐기성배양액인 FTM(Fluid Thioglycollate Media)을 이용하여 배양하였으며, Rugol's iodine으로 염색한 후 해부현미경 하에서 검사하였다. 바지락포자충의 감염 정도는 Mackin (1961)의 기준을 따랐으며 일부 시료는 Choi et al. (1989)의 정량적인 방법에 따라 NaOH로 처리한 후 혈구 계수기로 계수하였다. FTM 분석 결과 곰소만에서 채집된 모든 바지락 개체들은 바지락포자충에 감염된 것으로 나타나 감염율 (prevalence)은 $100\%$였다. Mackin의 기준에 따른 감염 정도 판정에서 평균 2.87로 나타나 중간 정도의 감염 정도를 나타냈다. 바지락 육중량 1g 당 바지락포자충의 개체수는 평균 709,028 개체였으며, 바지락 1개체당 최고 4,091,667 개체의 바지락포자충이 발견되었다. 곰소만에서 채집된 패류를 대상으로한 FTM 검사 결과, 굴에서는 바지락 포자충이 전혀 발견되지 않았으며, 새로막과 피뿔고둥에 대한 조사에서는 피조개 2 개체에서만 각 각 6, 10 개의 바지락 포자충이 발견되었고 피뿔고둥에서는 전혀 발견되지 않았다. 조직병리학적 관찰결과 바지락 아가미의 연결조직에서 무정형의 결절에 쌓여있는 직경 $6\~10\;\mu$m의 tropozoites를 발견하였다. 바지락의 비만도는 개체의 각장이 클수록 낮게 나타나는 경향을 보였으며, 바지락 포자충의 감염정도는 각장이 클수록 높게 나타났다. 바지락포자충은 개체에서 개체로 감염되는 관계로 바지락밀도가 높은 지역에서는 그 전염 속도가 높은 것으로 알려져 대량폐사의 원인 중 하나는 밀식으로 판단되었다. Mass mortality of the Manila clam, Ruditapes philippinarum has been reported all along the west and south coast of Korea for the past several years. As a pathogenic agent, Perkinsus sp., an endoparasitic protozoan has been identified in this study and believed to be responsible for the mass mortalities. Prevalence and infection intensity of Perkinsus sp. was investigated from a Manila clam population inhabiting at Komsoe Bay in the west coast where mass mortality of the clam has been reported. A total of 142 Manila clam, 50 oyster, Crassostrea gigas, 10 ark shell, Scapharca broughtonii, and 5 predatory gastropada, Rapana venosa were examined for the presence and the quantity of Perkinsus sp. Ray's fluid thioglycollate medium method (FTM method) with modified Mackin's infection intensity scale and Choi's quantitative method were used in detecting and quantifying the parasite. All individuals of R. philippinarum examined in this study were infected with Perkinsus sp., indicating $100\%$ prevalence while none of the oysters and the gastropods exhibited the parasite. Six to ten individual hypnospores of Perkinsus sp. were counted from the ark shells. The number of hypnospores in the clam tissues varied from 16,667 to 4,091,667, with a mean number of 1,077,628. Average infection intensity according to Mackin's was 2.87, indicating a moderate infection. A negative correlation was observed between the number of Perkinsus sp. in the tissue and the condition index, a ratio tissue wet weight to shell cavity volume. The clam size and the infection intensity in terms of total number of parasites were positively correlated; the bigger clam, the heavier infection. Such high number of Perkinsus sp. counted in the clams could be enough to cause physiological disturbance of clams, such as retarded growth and reproduction. It is also believed that such a high infection leads mortality of the clam via continuous draining of the energy by metabolic activities and reproduction of the parasites. Correlation between the condition index and the infection intensity observed in this study supports this hypothesis.

식품 기준·규격의 합리적 관리 ·운영에 관한 연구(Ⅰ) : 두부,식용유지, 전분의 분말상 원료에 관하여 Powdered marerials of Tofu, Edible oil, Starch

김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.

그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력

최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1

An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.

투석환자의 성생활 만족 및 관련요인

최경희,김은영,김진선 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2

Objectives: The purposes of this study were to examine the sexual satisfaction and to identify the factors related to sexual satisfaction of dialysis patients. Method: For this descriptive correlational study, a convenient sample of 96 hemo or peritoneal dialysis patients was selected. Data were collected using structured questionnaire and analyzed using the SPSS/PC 10.0. For data analysis, descriptive statistics, t-test, ANOVA, correlation. and stepwise multiple regression analysis were used. Results: Sexual satisfaction of the respondents was negatively changed after dialysis. The current level of sexual satisfaction was low. Dialysis patients with diabetes mellitus reported lower sexual satisfaction than their counterparts. The respondents' age and spousal support were significant predictors of sexual satisfaction in dialysis patients. and these two variables explained 22.7% of variance of respondents' sexual satisfaction. Conclusion: The results of this study demonstrated that there are great needs for development of intervention programs to improve sexual satisfaction of dialysis patients. To identify aging effect on sexual satisfaction. sexual satisfaction of dialysis patients is need to be compared with that of general population. Moreover, interventions to improve sexual satisfaction of dialysis patients should be included their spouses.