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Bloodborne Pathogen에 대한 임상병리사의 예방행태학적
조경진,이창규,안승일 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1
에이즈가 널리 전파되면서 임상병리사 들은 혈액유래감염원에 대한 노출에 대하여 보다 커다란 관심을 갖기 시작하였다. 이에 우리는 개인적특성이나 검사실의 체제가 개인의 예방습관이나 보호구착용수준에 얼마만한 영향을 미치는 지를 보기 위한 임상병리사 들의 개인보호를 위한 대책과 형태와 관한 연구를 실시하였는데 보호구착용수준과 예방습관은 낮은 것으로 나타났으며, 예방습관에 영향을 미치는 요인으로는 검사실내 관행과 기본안전관리체제로 나타났다. Occupational exposure to bloodbome pathogens has been the growing concern for the clinical laboratory scientists since the AIDS epidemic was propagated throughout the world. Accordingly we started a survey on the personal protective behaviors of clinical laboratory scientists to ascertain how the socio-economic and institutional characteristics affect to the levels of preventive behaviors or to the levels of PPE compliances. Major factors affecting the protective habits were PPE compliance, institutional customs and basic safety system.
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클로렐라(Chlorella pyrenoidosa) 단백질 추출을 위한 친환경 추출법 탐색
조경진,김민웅,김도균,한서진,강주홍,윤다현,최지선,김영목 한국수산과학회 2024 한국수산과학회지 Vol.57 No.6
In this study, we investigated eco-friendly physical and enzymatic methods for extracting proteins from Chlorella pyrenoidosa via cell wall decomposition. The physical methods used were hot-water extraction (HW), sonication (S), and ultrasonication (US), whereas the enzymatic methods included two cell wall-decomposing enzymes (cellulase and viscozyme L) and three proteolytic enzymes (microbial protease, papain, and bromelain) at a 1% substrate concentration. The results showed that HW and S were unsuitable for extracting chlorella proteins because of their low protein extraction yields. Conversely, among the physical treatment methods, US showed the highest protein extraction yield of 16.78±0.47%. However, physical methods can cause protein denaturation due to temperature increases with extended treatment time. In enzymatic treatment, only microbial protease proved effective, achieving the highest protein extraction yield of 36.26±2.32% after 6 h of treatment. The use of mixed enzymes did not significantly improve the yield compared to treatment with microbial protease alone. This study suggests that microbial protease is an effective method for protein extraction from chlorella and highlights its potential for application in the food industry as foundational data.
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Bloodborne Pathogen에 대한 임상병리사의 예방행태학적 연구
조경진,이창규,안승일 高麗大學校 倂設 保健大學 保健科學硏究所 1999 보건과학 학술 세미나 Vol.- No.7
에이즈가 널리 전파되면서 임상병리사 들은 혈액유래감염원에 대한 노출에 대하여 보다 커다란 관심을 갖기 시작하였다. 이에 우리는 개인적특성이나 검사실의 체제가 개인의 예방습관이나 보호구착용수준에 얼마만한 영향을 미치는 지를 보기 위한 임상병리사 들의 개인보호를 위한 대책과 행태와 관한 연구를 실시하였는데 보호구착용수준과 예방습관은 낮은 것으로 나타났으며, 예방습관에 영향을 미치는 요인으로는 검사실내 관행과 기본안전관리체제로 나타났다. Occupational exposure to bloodborne pathogens has been the growing concern for the clinical laboratory scientists since the AIDS epidemic was propagated throughout the world. Accordingly we started a survey on the personal protective measures or behaviors of clinical laboratory scientists to ascertain how the socio-economic and institutional characteristics affect to the levels of preventive behaviors or to the levels of PPE compliances. Major factors affecting the protective habits were PPE compliance, institutional customs and basic safety system.
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대장암 세포주 HT-29에 대한 제비꽃(Viola mandshurica) 추출물의 세포독성 효과
조경진,박은주,이승철,박해룡 대한암예방학회 2008 Journal of cancer prevention Vol.13 No.1
This study was performed to investigate the cytotoxic activity from Viola mandshurica (VM) extracts. Traditionally, VM has been used in the prevention and treatment of anti-inflammatory, diuretic. However, the cytotoxic activity of VM against cancer cells has not, until now, been elucidated. We found that the extracts of V. mandshurica (VME) have cytotoxic effects on HT-29 human colon cancer cells. As expected, VME inhibited growth of HT-29 cells in a dose-dependent manner as assessed by the MTT reduction assay, the LDH release assay, and colony formation assay. Interestingly, we also detected apoptotic bodies on Hoechst staining. These results indicate that VME contains bioactive materials with strong activity, and is a potential chemotherapeutic agent candidate against human colon cancer cells. (Cancer Prev Res 13, 26-32, 2008)
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조경진,황도연,이현주,현기훈,김태정,박덕훈 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.5
Purpose: This study was performed to evaluate the incidence of vasovagal reactions (VVRs) and the efficacy of lidocaine injection for prevention.Methods: One hundred seventeen patients diagnosed with hemorrhoids and scheduled to undergo a stapled hemorrhoidopexy (SH) were randomly divided according to submucosal injection to the rectum: lidocaine group (n = 53, lidocaine injected just before full closure of the stapler) and control group (n = 58). Outcomes included baseline patient characteristics (American Society of Anesthesiologists physical status classification, body mass index, diabetes mellitus, hypertension, and previous VVR history), vital signs during the operation, incidence of VVRs (hypotension, bradycardia, dizziness, diaphoresis, and nausea/vomiting), and postoperative complications (pain, bleeding, and urinary retention).Results: Baseline characteristics were similar between groups. The number of patients with lower abdominal pain after firing the stapler and incidence of dizziness were lower for the lidocaine group than for the control group (9.4% vs. 25.9%, P = 0.017; 0% vs. 8.6%, P = 0.035, respectively). However, there were no significant between-group differences in incidence of nausea and diaphoresis (0% vs. 3.4%, P = 0.172) and syncope (1.9% vs. 3.4%, P = 0.612). Fewer patients in the lidocaine group complained of postoperative pain (41.5% vs. 58.6%, P = 0.072), and these patients used analgesics less frequently than those in the control group (28.3% vs. 36.2%, P = 0.374).Conclusion: Patients who received a submucosal lidocaine injection prior to SH experienced less lower abdominal pain and dizziness compared with those who received standard treatment. A larger, more detailed prospective study is needed for further analysis.
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