서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

Immobilization with Ketamine HCI and Tiletamine-Zolazepam in Cynomolgus Monkeys

Myung-cheol Kim,Sung-hyeok Hong,Soo-jin Lee,Young-suk Kim,Jae-il Lee 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

with Ketamine HCl and Tiletamine-Zolazepam in Cynomolgus MonkeysJae-il Lee, Sung-hyeok Hong, Soo-jin Lee, Young-suk Kim and Myung-cheol Kim*Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, KoreaReceived March 4, 2003 / Accepted July 2, 2003J. Vet. Sci. (2003), 4(2), 187-191JOURNAL OFVeterinaryScience*Corresponding author: Myung-cheol Kim Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea Tel: +82-42-821-6757, Fax: +82-42-822-4216 E-mail: mckim@cnu.ac.kr

兒童行動目錄(CBCL)에 의한 國民學生의 行動問題 調査

홍강의,송혜양,김중술,홍경자,박성수 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.2

This is an epidemiological study of emotional/behavior problems in Korean elementary school children(total 2,399 : 1.236 boys, 1,163 girls) by empolying Children's Behavior Check List(CBCL) developed by Achenbach and Edelbrock(1983), to which 3 problem items were added for this study. A test-retest reliability of CBCL was was assessed by computing the Spearman-Browm correlation and the average correlation among items was. 72. The interparent agreeement was also assessed and the average correaltion between mother and father was. 62. The study subjects were drawm by stratified sampling from 5 schools in Korea ; 3 schools (A, B, C) from Seoul, one school(D) from a medium size city one school (E) from a rural town. School C is located in upper/middle-upper class residential area, School A and D in middle class, and School B and E in lower-middle/lower class. The present paper reports the prevalence of behavioral/emotional problems in relation to sex, grade, locality and socioeconomic variables. Some of the major findings were as follows ; 1) The mean total problem score excluding 3 additional items was 27.28 and did not differ significanthy according to sex and locality(Seoul vs non-Seoul), However, the mean total problem scores were significanthy different from school to school. The lowest score was observed in children of School C(22.15), higher scores for School B(30.89) and E(30.64) and in-between scores for the School A(27.58) and D(25.47). Father's education also had significant effect on the total problem scores : 31.46 for elementary of less 27.79 for middle and high school and 23.05 for college or more. As for to the grade, mean total score was lowest for the first graders(22.12), increasing up until 4th grade(29.83), then decreasing for 5th graders(26.81) and then relatively high score for the 6th graders(29.81). 2) Examination of each 122 problem items revealed that prevalence rate ranged from 2.1% to 61.7% : less than 5% for 13% items, 5-10% for 18 items, 10-20% for 31 items, 20-30% for 25 items, 30-40% for 15 items, 40-50% for 13 items, more than 50% for 7 items. Although sex did not make any difference in total problem scores, examination of the prevalence of each item revealed that 47 problem items were significanthy different between sexes : 26 items were more prevalent in boys and 21 items in girls. The items more prevalent for boys were externalizing problems such as hyperkinetic, aggressive and other behaviors and 21 items, more prevalent for girls were internalizing problems such as emotional and psychosomatic problems. School grade had significant effect in 47 items, only 3 of which showed lower prevalence in the younger children and the prevalence of 39 items were higher in older children. Significant differences were observed in 83 items, and 94 items, respectively according to school and father's education that could be considered to reflect socioeconomic status and it was reavealed that the lower the status, the higher the prevalence in most items. Items more common in upper class tend to be more anxiety-tension related(internalizing) and items more common in lower class tend to be more aggressive, hyperactive and other behavioval problems(externalizing). 3) Brief cross-cultural comparisons between the current study and other studies reported in the literature revealed major differences in several areas. The total problem score for Korean children was much higher than those of American and Dutch children, but lower than those of Canada and Chile. Although most of other studies reported higher total problem scores for boys, than for girls there was no sex difference in total problem score for Korean children. This was reflected in the finding of an almost equal numbers of items(26 for boys, 21 for girls) being more common than the other sex. Analyses by grade(age) also indicate major differences between Korean and American-Dutch children ; In contrast to the finding that total problem score was higher and larger number of items were more common for younger children in American and Dutch studies, they were higher for older children in Korean study. Socioeconomic variables seems to exert far more significant effect on the total score and the prevalence of each items in Korean study, when compared with American and Dutch studies. Further analyses of the data including a comparison with a clinic sample are deferred to another paper and so are the factor analysis results of 122 items into emotional/behavioral syndromes.

3DFT-CISS를 이용한 감각신경성 난청 환자의 MBI

김성원,여상원,김상후,김종수,조재흥,이동희,이승균 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

자궁경부 상피내병변과 침습성 편평세포 암종에서의 bcl-2 발현양상

성정희,오수섭,기근홍 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Background and Objectives: Squamous cell carcinomas (SCC) of the uterine cervix arise from the carcinoma in situ developed in a field of atypical squamous cell proliferation. So, clinical significance of the cervical intraepithelial neoplasm (CIN) are widely accepted. The purpose of this study is to investigate the oncoprotein changes in the sequence of low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), keratinizing type of squamous cell carcinoma (K-SCC) and nonkeratinizing type of squamous cell carcinoma (NK-SCC). Materials and Methods: Immunohistochemical stains for anti-bcl-2 oncoprotein to 120 conized cervical tiussues or resected uterus specimens diagnosed as squamous cell lseions including 30 cases of LSIL, 30 cases of HSIL, 30 cases of K-SCC, and 30 cases of NK-SCC were done. The evaluation of the bcl-2 immunostaining was based on the percentages of the positive neoplastic cells. And statistical analysis of data for the relation between each lesion was performed using the Student t-test. Results: The average positive cell rate was 2.0%, 4.44%, 6.25% and 13.57% in LSIL, HSIL, K-SCC, and NK-SCC, respectively. Statistically, immunoreactive positive cell rate of NK-SCC was significantly higher than those of LSIL (p=0.007) and HSIL (p=0.031). But, there was no significant difference of immunoreactive cell rate between K-SCC and HSIL. Conclusion: These results suggested that bcl-2 may play a role in a cervical tumorigenesis and prognostic relationship with NK-SCC.

자동차 공조용 핀형 열교환기의 성능특성에 관한 연구

홍경한,전상신,이승재,박찬수,권일욱,김재열,김병철,하옥남 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.4

Fin-tube type(Fin-type) heat exchanger has been tested in order to replace the heat exchanger of parallel flow type(P.F-type) which is now widly used in automobile air conditioning system. The following conclusions are drawn by the comparison of the characteristics of the heat exchangers. Evaporator and condenser capacities and COP(Coefficience of performance) were varied as with the compressor speed, outdoor air temperature and air flow rate changed, which much influenced on the characteristics of the air conditioning system. Evaporator and condenser capacities were increased with increasing compressor speed and outdoor air temperature. Evaporator and condenser pressures of Fin- type were decreased by 7% and 5% respectively compared with those of P.F-type. The COP of Fin-type was decreased with increasing outdoor air temperature and compressor speed. The COP of P.F-type was decreased by 14% compared with that of Fin-type.

UNITY3D를 활용한 원버튼 아케이드 게임 제작

장기홍, 김수균, 안성옥, 박대성 배재대학교 공학연구소 2012 공학논문집 Vol.14 No.1

Produced in the recent issue and mobile platform that you can easily enjoy a simple one-button arcade game. Leverage the UNITY3D Engine and 3D MAX, the detailed implementation of the game screen. Engine programming modeling of collision checks and 3D Object placement and 3D MAX modeling and design configuration screen. In other words, produced by blending the benefits of a button on the arcade genre of game achievements that you can easily enjoy a different genre of game that can be viewed in 3D graphics this game.

매복 하악 견치의 자가이식술을 이용한 치험례

홍성수,이상호,김동필 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.3

Autotransplantation is the transplantation of embeded, impacted, or unerupted tooth, into extraction socket or surgically prepared socket in the same individual. Clinically, successful autotransplantation must show radiolucent space(preiodontal ligament space) between transplanted tooth and supporting bone, lamina dura, no root resorption, no ankylosis, no inflammatory change, and physiologic tooth mobility. It is important that procedure is atraumatic, and the instruments should not contact the root surface during procedure. We performed autotransplantation of impacted mandibular canine that transversely located beneath the apices of the mandibular incisors with uncompletely developed apex. In radiographs and clinical evaluation, this transplant showed successful clinical finding except irregularity of mesial root surface after 14 months. It is concluded that transplantation of canine with 1/2∼3/4 root development provides a good chance of pulp survival, limited risk of root resorption and ensures sufficient final length, and is thus recommended.

17β-Estradiol의 심근 보호작용에 대한 연구 ; 재관류 부정맥을 유발한 동물실험

홍정석,김원,조규종,이미우,장성은,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: Although reperfusion certainly prevents tissue ischemia from possible cardiac death, several lines of evidence suggest that reperfusion may paradoxically aggravate the frequency of serious reperfusion-induced lethal arrhythmias. It has been reported that acute administration of estrogen at physiological concentrations reduced with myocardial ischemic injury in women with coronary heart disease. In studies with canines, acute administration by either the intra-muscular or the intra-coronary route similarly prevented ischemia and reperfusion dysrhythmias and also reduced the infarct size because the estrogen increased the distal coronary perfusion pressure, scavenged free radicals and had other effects during both ischemia and reperfusion. However, the canine heart is notoriously well collateralized. 17β-estradiol induces very little vasorelaxation in cat coronary rings, suggesting that increased ischemic myocardial blood flow dose not contribute to the protective effect. In the present study, employing a cat model of regional cardiac ischemia, we examined whether reperfusion rendered after acute administration of 17β-estradiol could lower the incidence of reperfusion-induced lethal arrhythmia and the death rate. Method: Adult mongrel male cats(n=31, 2.7∼4.5 kg) were anesthetized under positive-pressure artificial ventilation with room air. Electrocardiograms were recorded. The animals of the control group(n=15) were subjected to 20-minute left anterior descending coronary artery(LAD) occlusion followed by abrupt reperfusion. The animals in the experimental 17β-estradiol(2 or 20 ㎍/kg) group were subjected to ischemia/reperfusion insult following drug treatment: 17 β -estradiol was applied intravenously within the 60 seconds just before LAD ligation followed by abrupt reperfusion. The Fisher's exact test was used to compare the data from different animal groups(p<0.05). Results: The number of arrhythmias(ventricular premature beat, ventricular tachycardia and ventricular fibrillation) emerging during the reperfusion phase were not statistically different from that in the control group. The death rate in the 17β-estradiol 20㎍/kg group was lower from that in the control group(P value = 0.039). Conclusion: Acute administration of 17β -estradiol at a supraphysiological concentration might produce cardioprotective effects, not by modificating the coronary blood flow into the threatened myocardial region, but by other mechanisms that directly or indirectly increase the intrinsic myocardial ischemic tolerance in the cat during the reperfusion phase.