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장성은,문기찬,성경제,최지호,고재경,이정엽 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.1
We report herein a case of linear focal elastosis associated with striae distensae. A 17-year-old man presented with striae-like palpable bands on his lower back. Histologic examination revealed many fine wavy and fragmented bundles of elastic fibers in the dermis. He also had typical striae distensae on the knee area. This patient can be one more case to the theory that linear focal elastosis might be the keloidal repair of striae distensae.
장성은,문기찬,성경제,최지호,고재경,한만희 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.2
Methyldibromoglutaronitrile(MDGN) is a component of Euxyl K400, a preservative used in many skin care products in Europe. MDGN has been used in cosmetics in the United States and Korea. A sudden increased incidence of contact allergy from MDGN has been reported in 소디 United states. However, there has been no report in Korea. We report a case with persistent contact dermatitis from a cream containing Euxyl K400. Patch testing of cosmetics and of one of its ingredients, Euxyl K 400, revealed strong positive reactions. Upon testing 2-phenoxyethanol(one component of Euxyl K 400) and Euxyl K400 itself, Euxyl K400, not 2-phenoxyethanol showed a positive reaction. MDGN in Euxyl K400 is an important new sensitizer in cosmetics, with the increase of its use, it should be included in patch test battery of patients with allergic contact dermatitis.
장성은,문기찬,성경제,최지호,고재경 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.1
Lipomembranous fat necrosis is a special form of fat necrosis characterized by the presence of cystic cavities lined by crenelated hyaline membranes. Lipomembranous fat necrosis has been observed in the subcutaneous tissue associated with various conditions, mainly with ischemia. The term, nodular-cystic fat necrosis was coined to describe a characteristic form of encapsulated subcutaneous fat necrosis resulting form encapsulated lipoma associated with trauma or ischemia. We herein report a case of lipomembranous fat necrosis associated with vascular insufficiency and possibly associated with nodular-cystic fat necrosis, and discuss the common pathogenesis of the two disorders.
장성은,문기찬,성경제,최지호,고재경,김소형 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.2
The differentiation between cutaneous pseudolymphomas and primary cutaneous lymphomas is often very difficult, but it is important because each of them has different therapeutic consequences. We report herein a case of cutaneous B-cell pseudolymphoma probably induced by frequent use of hair dye which mimicked true B-cell lymphoma histologically. Histopathologic examination revealed diffuse, extensive infiltration of atypical B cells on the first biopsy, but 2 years later, a rebiopsy revealed well defined lymphoid follicles in the upper dermis. There was no monoclonality in immunoglobulin gene rearrangement. The skin lesions were resolved after one month with intra-lesional injection of triamcinolone.
대상포진으로 내원한 환자에서 발견된 후천성 면역결핍 증후군
장성은,문기찬,성경제,최지호,고재경,정준규 대한피부과학회 1999 대한피부과학회지 Vol.37 No.5
The cutaneous manifestations of Acquired immunodeficiency syndrome(AIDS) include many conditions and can give some diagnostic clues to early detection of HIV infection. We report the case of a 32-year old man in whom AIDS initially manifested itself with herpes zoster and multiple episodes of purpuras(idiopathic thrombocytopenic purpura). He also had seborrheic dermatitis, oral candidiasis, and proximal subungual onychomycosis.
장성은,채병윤,Jang, Sung-Eun,Chae, Byung-Yoon 대한한방안이비인후피부과학회 1996 한방안이비인후피부과학회지 Vol.9 No.1
We think that we know what alopecia is. But in detail, we have nothing of alopecia areata. Many kinds of alopecia make us be confused. So, I studied the history ( name, cause, treatment etc,) of alopecia areata through the oriental and occidental medical books. As a result, the investigation of alopecia areata was led to the next conclusions 1. Synonyms of alopecia areata are Bandok(斑禿), Docbal(禿髮), Guyjidu(귀지두), Guychedu(鬼剃頭), Gyobalsun(咬髮癬). 2. Generally, the cause of alopecia areata is classified into three groups. Those are hyeolheopungjo(血虛風燥), Chichehyeoleo(氣滯血瘀), Gansinbujoc(肝腎不足). 3. The important internal uses of alopecia areata are Sineungyangjin-Dan(神應養眞丹), Soyosan plus Tonggyuhwalhyeoltang(逍遙散合通竅活血湯), Chilbomiyuom-Dan(七寶美髥丹) etc. 4. The important external uses of alopecia areata are haeaetang(海艾湯), Suncheukbackyeop(鮮側柏葉), Old ginger(老薑), Leaf of mulberry tree(桑葉) etc. 5. The kinds of Acupunture therapy are Maehwachim(梅花針), Chilsungchim(七星針), Ear acupunture(耳針) etc.
건성 병변내 침윤된 림프구의 피부림프구 관련 항원 발현에 미치는 cyclosporine 의 치료 효과
장성은,문기찬,성경제,최지호,고재경,민광선 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.3
The cutaneous lymphocyte-associated antigen (CLA) has been proposed as a homing receptor for the selective migration of memory T cells into the skin. To investigate the effect of cyclosporine on the expression of CLA of the lymphocytes infiltrated in psoriatic lesions, CLA expression was assessed by the immunohistochemistry(HECA-452 epitope) with skin samples from 9 patients at time sequential(before treatment, 3 weeks, 6 weeks, and 12 weeks after initiation of treatment). CD3+ or CD4+ cells were also analyzed by immunohistochemistry on the same skin samples. Mean CLA expression on the infiltrated lymphocytes was decreased continuously during 12 weeks treatment with a further decrease during 3-6 weeks. CD3+ or CD4+ cells were decreased rapidly during the first 3 weeks of treatment. Although most CLA+ lymphocytes overlap with CD3 or CD4+ cells, cyclosporine could have therapeutic effects by differential decrease of CD3, CD4, or CLA+ cells during treatment period. In conclusion, reflecting the importance of CLA expression on the lymphocytes infiltrated in psoriatic lesion, one of the mechanisms to treat psoriasis may result from selective decrease of CLA+ T cells by cyclosporine in psoriatic lesions.
ADHD 아동의 긍정적 행동지원을 통한 문제행동 단일사례연구
장성은,최성규 한국초등특수교육학회 2011 초등특수교육연구 Vol.13 No.1
본 연구는 ADHD 아동의 문제행동을 가정, 치료실, 수학교실에서 긍정적 행동지원을 통해 감소시키고 그 효과가 지속되었는지를 2년 후 추적관찰을 실시하였다. 대상자는 10세 된 ADHD 남자 아동 1명이며 상황 간 중다기초선 설계를 이용, 문제행동을 가정, 치료실, 수학교실에서 긍정적 행동지원인 토큰강화를 통해 중재하고자 하였다. 연구결과 긍정적 행동지원은 대상자의 문제행동에 효과가 있었으며 2년 후 추적관찰 결과 특히 바람직하지 않는 착석 자세 개선에 효과가 있었다. 본 연구의 제한점과 함께 향후 연구문제가 제안되었다.