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한국인에서의 피부 림프종의 임상 및 병리조직학적 연구 : 대한피부과학회 피부병리연구분과위원회 공동연구
이미우,고재경,권경술,김낙인,김상원,김수남,김방순,김유찬,김종민,명기범,박장규,서기석,손숙자,송은섭,조광현,조백기,오지원,원영호,윤태영,이규석,이석종,이용석,이원수,이일수,임철완,장경애,장성남,함정희 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.1
Background : The relative frequency and clinicopathologic characteristics of lymphomas vary according to geography and race. Data on the features of cutaneous lymphoma in Korea we limited. Objective : The aim of this study was to document the relative occurrence, the clinical and histopathological features of cutaneous lymphomas in Korea. Methods : The Korean Dermatopathology Research Group conducted a review of nationwide collection of 80 cutaneous lymphomas, diagnosed at 23 institutes over recent 3-year period. Clinical records and pathology slides of the patients were reviewed retrospectively. Results and Conclusion : 1. Korea has a higher rate of T-cell lymphoma and NK/T cell lymphoma and a much lower rate of cutaneous B cell lymphoma. 2. The relative frequency of the major diagnostic group according to WHO classification was as follows mycosis fungoides/Sezary syndrome, 42.5%; anaplastic large cell lymphoma, 19%; nasal and nasal type NK/T cell lymphoma, 15%; subcutaneous panniculitis-like T cell lymphoma, 11%; peripheral T cell lymphoma, unspecified, 7.5%; follicular lymphoma, 3%; marginal zone Iymphorna, 1%; angioimmunoblastic lymphadenopathy, 1%. 3. Compared with Western countries, the rate of nasal and nasal-type NK/T cell lymphoma and subcutaneous panniculitis-like T cell lymphoma were much higher. Therefore, The EORTC classification is not effective in dealing with Korean cases of cutaneous lymphoma. We consider the principles of the WHO classification are applicable to the Korean cases of cutaneous lymphoma. (Korean J Dermatol 2003;41(1) : 48∼57)
한국인에서의 악성 흑생종에 대한 임상 및 병리 조직학적 연구 : 대한피부과학회 피부병리연구분과위원회 공동연구
이미우,고재경,권경술,김낙인,김상원,김수남,김방순,김유찬,김종민,명기범,박장규,서기석,손숙자,송은섭,조광현,조백기,오지원,원영호,윤태영,이규석,이석종,이용석,이원수,이일수,임철완,장경애,장성남,함정희 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.1
Background : Malignant melanoma in Korea has been increasing as in other countries, but there is no nationwide survey of malignant melanoma in Korea. Objective : The aim of this study was to document the clinical and histopathological features of cutaneous melanoma in Korea. Methods : The Dermatopathology Research Group conducted a review of nationwide collection of109 primary cutaneous melanomas, diagnosed at 23 institutes over a recent 3-year period. Clinical records and pathology slides of the patients were reviewed retrospectively. Results and Conclusion : 1. The peak age was the 7th decade with the mean age of 58.1 years. Korea has a higher rate of acral melanoma and much lower rate of lentigo maligna melanoma. 2. Major component tumor cell was spindle cell type. 3. Clark level of tumor was Ⅲ or more and Breslow depth was 2 ㎜ or more at the time of the first diagnosis in many cases (62%). 4. Pre-existing melanocytic nevus was present in a few cases (3 cases). 5. All these features suggest that the racial difference between the Korean and the Caucasian is evident. We also suggest that an early detection program is very important to cure this malignant tumor. (Korean J Dermatol 2003;41(1) 43∼47)