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      • KCI등재

        한국인 직무 스트레스 측정도구의 개발 및 표준화

        장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

      • 공복 시 Caffeine 투여 후 일회성 운동이 흰쥐의 인슐린 및 골격근의 GLUT-4 발현에 미치는 영향

        정일규,오명진,김영표,김종오,윤재석,서태범,윤진환 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

        This study was done to investigate the effects of caffeine ingestion on the expression of GLUT-4 in rats' skeletal muscle(soleus m) and blood insulin level after 12 hr fasting condition and one hour treadmill running. Total 19 rats(Sprague-Dawley) who were 7week Did were used for experimental subjects and raised for 1week in the room controled the air temperature and relative humudity(22℃ and 50%). They were divided three groups ; 12hr fasting group(F group, n=5), fasting+exercise group(FE, n= 7) and fasting+caffeine+exercise group(FCE group, n=7). FG and FCE group performed treadmill running for one hour and the treadmill speed was 18m/min that was supposed to be moderate exercise to rats. Each Dr rats in FCE group was forced to he given the caffeine solution(5mg/kg, Sigma Chemical co.) through stainless steel tube directly to their stomachs one hour before treadmill exercise. Immediately after treadmill running, we anesthetized them with the mixed solution(Ketamin 80g/kg and Rompun 5ml/kg) to draw 3ml blood from heart four insulin analysis and then obtained the rats' soleus muscle for GLUT-4 expression. We found that FCE group showed significantly higher GLUT - expression then the other groups and FE group showed the lowest GLUT-4 expression. This rusults suggest that the endurance type of exercise in fasting condition inhibit the GLUT-4 expression in working muscle and the caffeine helped to facilitate the GLUT-4 expression during endurance type of exercise. The future studies needed to confirm the action of caffeine to increase the GLUT- 4 and the mechanism.

      • SCOPUSKCI등재
      • 양극성장애와 새로운 항경련제의 효과

        남범우,서정석,정헌종,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.13 No.-

        Bipolar disorder, like epilepsy and migraine, is episodic in nature and psychiatric illness requiring lifelong treatment. So, it should not be surprising that anticonvulsants such as carbamazepine and valproate have proven efficacy as mood stabilizers. The newer anticonvulsants such as lamotrigine, gabapentin, topiramate, oxcarbazepine, tiagabine, and zonisamide may also be effective treatments for bipolar disorder. Identifying an anticonvulsant for use in bipolar disorder should take into account not only the pathophysiology of bipolar disorder but also the mechanism of action of the anticonvulsant. Evidence for effectiveness of these novel antiepileptic drugs in treating acute mania and depression as well as in preventing the recurrence of mania and depression is reviewed. In conclusion, although the novel anticonvulsants appear to be clinically useful, more controlled trials are needed to assess the effectiveness in bipolar disorder.

      • 뇌졸중후 우울증

        문석우,서정석,남범우,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

        In recent years, depression is most commonly reported psychiatric condition after stroke, poststroke depression(PSD) has attracted world-wide interest. This review focuses on the major research themes that have emerged. Pooled data from studies, have wide variation in results is due to different criteria for patient selection, different evaluation methods, diagnostic criteria and poststroke intervals, conducted throughout the world have found prevalence rates for from 18% to 65%. The diagnosis of PSD is most appropriately based on a structured mental state exam and DSM-N criteria for depression due to stroke with major depressive-like episode or depressive features. Rarely, poststroke patients may also develop bipolar mood disorder. The treatment of PSD, single antidepressant showing efficacy and electroconvulsive theraphy(ECT) and behavioral therapies have also effective. The progression of recovery following stroke can be altered by treating depression, which has been shown to improve recovery in activities of daily living(ADL) and cognitive impairment and to decreased mortality. The mechanisms underlying the association of stroke and mood disorder are important areas for future investigation.

      • 식이 상태와 카페인 투여가 일회적 운동 시 흰쥐 가자미근의 제 4형 당수송체에 미치는 영향

        김광찬,김종오,오명진,윤재석,서태범,윤진환,정일규 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

        The purpose of this study was to evaluate the effects of diet condition and caffeine ingestion prior to long distance treadmill running on the GLUT-4 protein expression in Sprague-Dawley rats' soleus muscle. Total is rats were used For subjects and assigned to six groups: Fasting control(FaC group), feeding control(FeC), asting+exercise(FaE), feeding +exercise(FeE), Fasting +caffeine+exercise(FaCE), and Feeding+caffeine+exercise(FeCE). Each animal belongs to fasting group was forced to be in fasting state at least for 14 hours, The food was provided to each rat in feeding group 12minutes prior to treadmill running and the caffeine was ingested through the stainless steel tube 60minutes prior to exercise. All rats in exercise groups were forced to perform treadmill running for B9 minutes at the speed of 18m/min, and 0%grade, immediately after exercise, all animal was anesthetized by Chlorofolm (DC Chemical, Co, Ltd) and about 10ml of blood was drawn from each animal's heart and than soleus muscle was exposed and separated from the rat's leg. we found that the GLUT-4 in feeding groups increased much significantly compared to fasting groups(p<.05). The exercise in fasting state appeared to suppress the expression of GLUT-4 protein different from the exercise in feeding state. Cafreine ingestion prior to treadmill running of 60 minutes induced the significant increase or GLUT-4 protein expression both in fasting or feeding states.

      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • 정전 열 접합을 이용한 Multi-Substrate Bonding

        이덕중,주병권,최우범,한정인,조경익,이광배,장진,오명환 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

        We performed silicon-to-glass bonding using silicon direct bonding followed by anodic bonding(SDAB). Initial bonding between glass and silicon was caused by the hydrophilic surfaces of silicon and glass ensemble using silicon direct bonding(SDB) method. We found that the bonded specimen using SDAB process had higher strength than one using anodic bonding process only. We performed multiple layer bonding by SDAB, which is glass- silicon -glass as sandwich structure. In the silicon wafer, the (1mm x 2mm x 500μm)-sized cavity was formed by the anisotropic etching of the silicon substrate in EPW(Ethylendiamin-Pyrocatechol-Water). And, the cavity was sealed with glass wafers by SDAB method.

      • SCOPUSSCIEKCI등재

        불소도포가 교정환자의 타액내 Streptococcus mutans 수에 미치는 영향

        손우성,김형일,김진범,배원정 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.1

        The effect of topical application on the number of S. mutans was tested in a group of 44 orthodontic patients (mean age, 12Y 3M). They were divided into 5 groups according to the method using NaF and SnF₂. The number of S. mutans CFU were counted in stimulated saliva of each subject at baseline, and after one, two, three, and eight weeks. The following results were obtained. 1. In NaF rinsing group, and NaF topical application and NaF rinsing group, the number of S. mutans per ㎖ saliva was not significantly changed. 2. In SnF₂topical application group, and SnF₂topical and NaF rinsing group, the number of S. mutans per ㎖ saliva was significantly reduced. 3. After 8 weeks, there were no significant reduction of the number of S. mutans in comparison with baseline.

      • 빛에 대한 국민학교 학생들의 개념조사

        김한호,정진우,최병순,김범기,권재술 한국교원대학교 과학교육연구소 1993 청람과학교육연구논총 Vol.3 No.1

        The purpose of this study was to investigate children's(K-5) conceptions about light in Korea. The two aspect of children's conceptions about light were identified: the sources of light, the nature of vision. Data were collected from 92 children by a mixture of writing, drawing and interview, and were analysed by systematic networks. The major findings of this study were as follows: 1. Children showed an awareness of a wide variety of sources of light. The predominant sources exampled by children were primary sources. 2. Children explained vision as intentional actvivty of seeing Seeing. means action that move their heal or eyes to the objects. Infants(K-1) did not recognize that light are needed for vision. 3. A notable features in children's conceptions about light were context-dependent

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