초음파 뇨량검출 센서의 제작 및 방광 벽간거리와 뇨량과의 상관관계에 관한 연구

최흥호,이응혁 한국센서학회 2000 센서학회지 Vol.9 No.4

In this paper, we studied the ultrasonic urine volume sensor of urinary alarm system for home use to detect the time of urination as a assistive methodology for the incontinence patients and the correlation between urine volume and bladder interwall distance by using developed sensor. The developed sensor was designed to minimize the measurement error by using ultrasound with 2.25 MHz center frequency which provides higher resolution as well as longer penetration depth. To verify usefulness of the developed sensor, we performed a preliminary experiment of estimating bladder volume from the measured distance between interior and posterior wall of bladder. In the preliminary experiment, bladder volume estimated from the result using a commercial ultrasonography system. The experimental results show there exists god correlation between the actual urine volume and the measured interwall distance of the bladder. In conclusion, the developed ultrasound bladder volume sensor can be applied to an urine alarm system which provides patient the exact time of urination, it will be contribute in health care and welfare society.

2D 영상보간:부화소 단위의 에지 검출

최재호,이종수,강금부,양우석 한국센서학회 1998 센서학회지 Vol.7 No.5

In this paper, we present a new interpolation scheme for image enhancement using nonlinear operator. In general, interpolation techniques are based on linear operators which are essentially lowpass filters, hence, they tend to blur fine details in the original image. In our approach, the operator itself balances the strength of its sharpening and noise suppressing components according to the properties of the input image data.

조사료의 종류가 홀스타인 송아지 유선의 발달 , 반추위 돌기 및 성장률에 미치는 영향

조광근,최윤재,박영우,윤연화,한영근,윤상기,권웅기 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.6

본 연구는 홀스타인 송아지에 대한 세 종류의 조사료가 유선조직, 반추위 유두, 번식성적 및 성장률에 미치는 영향을 조사하기 위하여 실시하였다. 출생 후 4일된 송아지(42.9±0.9㎏) 24두를 무작위로 선발하여 출생 후 4∼44일까지 전유를 급여하다가 45일에 그룹 1은 볏짚, 그룹 2는 오차드 그래스, 그룹 3은 알괄파를 급여하였다. 또한 유선조직과 반추위의 발달을 측정하기 위하여 3, 9, 18개월령에 도달하였을 때 각 처리구의 송아지를 1마리씩 도살하였다. 알팔파를 급여한 그룹 3은 다른 처리구에 비하여 중체율이 높았으며, 그룹 2는 영양소 이용률과 번식성적이 높은 경향을 나타내었다. 반추위의 무게는 3개월령 도달시에는 그룹 3이 가장 무거웠으나, 9개월과 18개월령 도달시에는 그룹 2에서 가장 무거운 것으로 나타났다. 반추위의 유두 수는 유두의 성장과 함께 일반적으로 감소하는 경향을 나타내어 유두의 길이와 유두 수와는 서로 상대적인 관계를 나타내었다. 유선의 기능적 활성을 나타내는 RNA/DNA 함량은 3개월 시에는 그룹 3이 가장 낮은 경향을 보였으나 9, 18개월 시에는 반대로 가장 높은 경향으로 나타났으며, 유선세포의 크기를 나타내는 protein/DNA 함량은 18개월 시에 그룹 2가 가장 높은 경향을 보였다. 결론적으로 본 연구에서 볏짚은 반추위의 초기 발달을 촉진하고 알팔파와 오차드그래스는 성장과 번식성적을 증가시키며 또한 초기에 유선의 발달을 촉진시키는 것으로 나타났다. Twenty-four Holstein calves were used to evaluate the effects of three different forages on growth and reproductive performances, and ruminal papillary and mammary developments. Four-day-old Holstein calves weighing 42.9±0.9 ㎏ were randomly assigned to three forage groups of rice straw (group 1), orchard grass hay (group 2), and alfalfa (group 3). All calves received whole milk from day 4 through day 44. At 45 days of age, the animals were assigned at random to one of the three dietary treatments. When calves reached the ages of 3, 9, and 18 months, one calf in each group was sacrifced for evaluation of ruminal and mammary tissue developments. Calves of group 3 gained more body weight than those of other groups, while group 2 showed an effective nutrient utilization and reproduction performance. At 3 months, the stomach weight of group 3 was the highest, however, group 2 provided the highest stomach weight at 9 and 18 months. A remarkable reduction in papillae number was observed in the rumens of all 3- to 9-month-old heifers. A decrease in number of these papillae was observed in all groups exhibiting papillary growth. There was a reciprocal relationship between the number and the length of ruminal papillae. Among the 3-month-old calves, the functional activity (RNAI DNA contents) of the mammary glands of group 3 was lower than those of other groups, whereas the trend was opposite for 9- and 18-month-old heifers. The size of mammary cell (protein / DNA contents) was the greatest for group 2 at 18 months of age. The results suggest that rice straw stimulated earlier development of rumen. Alfalfa and orchard grass improved the growth, reproduction performance, and earlier development of mammary glands.

가토에서 CCNU 로 유발된 골수 저형성증의 혈액학적 소견과 골수스캔의 변화에 관한 연구

김승택,이명철,최두혁,고창순,김병국,이문호,박선양,최성재,김노경,최영희 대한내과학회 1986 대한내과학회지 Vol.30 No.1

To understand systematically the hematological changes including the bone marrow changes in chemotherapeutic agent-induced bone marrow hypoplasia and to define the relationship between hematological and bone marrow scan findings and prognosis of the hypoplasia, CCNU (lomustine) was given orally to 44 rabbits to induce hypoplasia of the bone marrow. And serial changes of peripheral blood and bone marrow findings and (111)In Cl(3)((111)In scan)/(99m)Tc tin colloid bone marrow scan((99m)Tc scan) were checked before and after induction of hypoplasia. With assessment of 28 evaluable rabbits, the following results were obtained: 1) Significant hypoplasia of the bone marrow developed around day 4 of CCNU administration and recovered around day 14(cellularity 51,4±13.5% and 24. 5±14.97o before and after CCNU respectively, p<005). Megakaryocyte count was significantly depressed from 95.67,26% to 36.7$gt;31.82%(P$lt;0.005). M: E ratio was decreased from 162±1.19 to 0, 0.5$lt;0. 43(p±0.005). Shift to left(475), maturation a(40%), naked nucleus and degenerated cells(20%), increase of lymphocytes(47%), monocytes and reticulum cells were also found. 2) The uptake ratio of the 99(m)Tc tin colloid bone marrow scan was markedly increased in contrast to the depression of the bone marrow(4.4±2.12 and 14.1±7.06 before and 4 days after CCNU, respectively, p40. 005). Tc scan uptake ratio was inversely related to the cellularity(r=-0.442, p$lt;0.05) and megakaryocyte number of the bone marrow(r= 0.89, p< 0.01) and peripheral blood granulocyte (r = 0. 54. Pg0.01) and platelet count(r=0.40, p$lt;0.05). There was not significant correlation between (111)In scan uptake ratio and hematologic parameters. 3) The amplitude of the change of the (99m)Tc scan uptake ratio was significantly related to the prognosis of the rabbits with experimentally induced hypoplasia of the bone marrow(dead 5.1±2,67, survivors 2,5±0.96, P<0.01). The change of the (111)In scan uptake ratio was not related to the prognosis of these rabbits. In experimentally induced rrow hypoplasia, morphologic changes in addition to the numerical changes of the bone marrow elements were observed. And serial (99)Tc scan of the bone marrow appears to be helpful assessing the severity and predicting the outcome of bone marrow hypoplasia.

당뇨병유발백서에서 급성패혈증 병발시 적혈구막지질과산화의 변화

박성우,홍성관,유형준,장대영,강승식,유재명,임성희,최문기,노정우,이규만 대한당뇨병학회 1994 Diabetes and Metabolism Journal Vol.18 No.3

급성 심근경색증 초기 진단에 latex 응집을 이용한 혈청 myoglobin 측정의 임상적 의의

박영배,서정돈,최윤식,이영우,오병희,손대원,임하진,김유우,박명희 대한내과학회 1987 대한내과학회지 Vol.32 No.2

We evaluated the diagnostic usefulness of latexagglutination test for elevated serum myoglobin as a screening test in the early phase of acute myocardial infarction and 21 patients with chest pain mimicking acute myocardial infarction were included in this study. Result was compared with serum myoglobin level measured by radioimmunoassay (RIA) in every case. The Following results were obtained: 1) When serum myoglobin levels measured by RIA below 85ng/㎖ were regarded as normal, this test showed sensitivity of 82%, specificity of 95%. 2) In latex-agglutionation test for elevated serum myoglobin, test results were interpreted as negative, weakly positive and positive. If we regard weakly positive tests as positive, sensitivity was 93% and specificity was 62%. In contrast, if we regard weakly positive tests as negative specificity rose to 100% while sensitivity reduced to 75%. 3) Agreement rate of both test was k=0.59. It is suggested that latex-agglutination test for elevated serum myoglobin is helpful in ruling out acute myocardial infarction when test result is negative, and that it can be used as a screening test in the early phase of acute myocardial infarction because of its rapidity and simplicity in performing the procedure.

인공판막 재대치험예에서의 판막실패의 양상

박영배,김유호,서정돈,최윤식,이영우,오병희,도문홍,최동주,전은석 대한내과학회 1987 대한내과학회지 Vol.32 No.3

In order to observe the aspects of prosthetic cardiac valve failure, we analyzed 26 cases of Redo operation among 1081 cases of valve replacemant performed from Jan. 1961. to July 1986. The results are as follows; 1) Crude Redo operation rate was 2.4%. 2) The most common cause or prosthetic cardiac valve failure was the primary tissue failure (73%) 8r the PVE was the 2nd (15.4%). 3) Mean valve implantation time was 47.7 months. Implantation time in the child group was shorter than in adult by 6.8 months, In the primary tissue failure group (19 cases) implantation time in the child was 42.8 months 8z in adult, 66.8 months. (P$lt;0.05) In conclusion, the durability of tissue valves was significantly decreased in the child age group because of increased propensity for calcification, so the preference of tissue valves especially in this age group should be reconsidered.

Castleman 씨 병에 동반된 신유전분증

김연수,한진석,이정상,김병국,이중건,정윤철,이진학,최영진,안규리,김성권,이현순 대한내과학회 1994 대한내과학회지 Vol.46 No.2

Castlemam's disease is an asymptomatic and benign lymph node hyperplasia which is frequently manifested as mediastinal mass in over 70% of cases. Amyloidosis is rarely associated with Castleman's disease. Recently we experienced a patient with nephrotic syndrome due to renal amyloidosis who had been previously diagnosed as Castleman's disease of retroperitoneal lymph node enlargement. A 47-year old woman was admitted because of generalized edema and chest tightness. Five months ago she diagnosed as Castlman's disease-plasma cell type, of retroperitoneal lymph node enlargement. The patient was followed up through outpatient department without any specific medication. Physical examination showed pale conjunctivae, palpable mass on epigastric area and pretibial pitting edema. The hemoglobin, leukocyte count and erythrocyte sedimentation rate were 96 g/L, 5.9×109/L and 127 mm/hour, respectively. The blood urea nitogen was 3.6 mmol/L and creatinine was 88 umol/L. The urinalysis showed 3 positive for albumin. Twentyfour hour urine contained 16.6 grams of protein. A computerized tomographic (CT) scan of the abdomen disclosed multiple lymph node enlargement at mesentery. Percutaneous needle biopsy of kidney showed massive infiltration of pale pinkish amorphous material in the glomerular tuft forming large nodules. Ultrastructural examination exhibited heavy deposition of amyloid fibrils in the mesangium and perpendicular to glomerular basement membrane. Polarizing microscopy with Congo-red stain revealed prominent yellow green birefringence in glomeruli, tubules and interstitium.

Semi - continuous Culture 방법을 이용한 Condensed Tannin 의 한국재래산양 반추위 섬유소 분해 미생물의 활성에 미치는 영향

배귀석,이상석,최종원,박상엽,장문백,하종규,최일,배희동,김종민 한국낙농학회 1999 韓國酪農學會誌 Vol.21 No.2

당뇨성망막증에서의 방사성핵종 망막신티그라피의 이용에 관한 연구

이상우,박영태,이형호,최승환,안일민,서순규,진용한,이태수 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.1