血液疾患에 있어서의 放射性同位元素의 應用

李文鎬 醫藥係社 1955 綜合 醫學 Vol.12 No.9

사회현상의 "이해" : 질적 조사가 사회학에서 갖는 의미

이문호 한국사회문화학회 2000 사회와 문화 Vol.12 No.-

This contribution deals with the characteristics of qualitative research, imaging social research as detective. The standardization of quantitative research is criticized from the view of sociological "Verstehen". It is demonstrated through two examples in German industry sociology that the "controlled flexibility" of qualitative research is suitable to discover specific features and varieties of social phenomena. That's why qualitative research ist necessary especially in the period of social change, now globalization.

차세대 이동통신 시스템을 위한 핸드오프 방법

이문호 한국정보기술응용학회 2005 한국정보기술응용학회학술대회 Vol.2005 No.1

갑상선질환에 관한 연구 : 20여년간의 핵의학교실 업적을 중심으로

이문호 대한핵의학회 1982 핵의학 분자영상 Vol.16 No.2

Several recent advances in our knowledge of thyroid physiology have broad application to the diagnosis and management of thyroid disorders. Foy in the thyroid, more than other end-ocrine organs, pathophysiology can he translated directly into the diagnosis and management of thyroid disease. Graves' disease is a syndrome including goiter with hyperthyroidism, exophthalmos and dermopathy. The pathogenesis of Graves' disease is not yet clearly identified, but various autoantibodies ta the thyroid gland and immunapathalogic studie indicate that autoimmune processes are involved in the pathogenesis of the disease. The diagnosis and management of Graves' disease are largely dependent on radionuclide technique as radioimmunoassay, radioactive iodine therapy and so on. Several laboratory tests are also developed to determine the remission of this disease including TRH stimulation test, T3, suppression test and detection of thyroid stimulating immunoglobulins. Autoimmune thyroiditis is almost certainly a primary immunologic disease and the incidence tends to increase recently, mainly due to the application of biopsy technique is thyroid diseases. Thyroid nodules have been a great challege to physicians because of the possibility of malignancy. But recently, cytologic examination of thyroid aspirate provides a very simple and also reliable diagnostic method in patients with thyroid nodules. In 163 patients with thyroid nodules, only 19.3% was revealed to be malignant. Therefore cytglogic examination of thyroid aspirate and thyroid biopsy should be included in the diagnosis of nodular patients prior to surgical intervention. In this paper, a comprehensive review is presented on the pathogenesis, clinical features, laboratory findings and therapeutic modalities of various thyroid diseases on the basis of over 80 researches performed during the past 20 years at radioisotope clinic, Seoul National University Hospital.

글로벌스타 시스템 및 사업 소개

이문호,Lee, Mun-Ho 한국위성정보통신학회 1998 위성통신과 우주산업 Vol.6 No.2

디지털 통신과 퍼지논리의 효시인 간단한 정낭 시스템 ( A Simple Jung-Nang System of the Beginning Digital Communication and Fuzzy Logic )

이문호 대한전자공학회 1993 대한전자공학회 학술대회 Vol.1993 No.1

영상 압축을 위한 새로운 정낭 VLC CODEC 구현 ( A Jong-Nang VLC CODEC for Image Data Compression )

이문호,최승배,박주용 대한전자공학회 1994 대한전자공학회 학술대회 Vol.1994 No.1

가우스(1855)의 동전 한 닢

이문호 대한전자공학회 2011 전자공학회지 Vol.38 No.11

갑상선질환의 Thyroglobulin에 관한 연구(예보)

이문호,김석근,임수덕 대한핵의학회 1970 핵의학 분자영상 Vol.4 No.1

각종 갑상선질환 24예의 혈청을 immuno-electrophoresis로 분석한 후 specific antihuman thyroglobulin rabbit serum으로 반응시켜 이들 환자들에 대한 thyroglobulin의 변화상을 관찰한 바 그 성적은 다음과 같다. 1) 각종 갑상선질환의 공통된 혈청성분의 변화는 19 S globulin인 IgM의 증가 (24예중 23예로 95.8%)와 alpha globulin의증가 (24예중 24예로 100%) 그리고 7 S globulin인 IgA는 약간 증가 (24예중 7예로 29.2%)를 볼 수 있었다. 2) Immuno-eletrophoresis로 분석된 갑상선질환혈청에서의 thyroglobulin의 검출결과는 증가가 24예중 12예(50%)였고 불변이 24예중 10예(41.7%), 무검출이 24예중 2예(8.3%)였다. In recent with development of immuno-electrophoresis, more acurate analysis of the serum protein became possible. However, there is few reports in the literature which investigated the changes of the immunoglobulin compared with electrophoretically fractioned serum thyroglobulin in the patients with various thyroid diseases. The purpose of this report is to investigate the changes of thyroglobulin in various thyroid diseases by the method of immuno-electrophoresis and to compare the results with serum protein fractionated by the method of agar-gel micro-electrophoresis. Materials and Methods: Sera from 9 patients with diffuse toxic goiter, 2 nodular nontoxic goiter, 2 thyroiditis, 3 hypothyroidism, 1 thyroid cancer, 7 cystic degeneration of the thyroid gland, and 10 normal subject were taken. All cases were confirmed by various laboratory thyroid function tests and thyroid needle biopsy. Immuno-electrophoretic analysis of the serum were performed by Scheidegger's modified micro-immuno-electrophoretic method. The antiserum was obtained from the Travenol Laboratories International, Hyland Products Division and was rabbit anti-human thyroglobulin. Microscope slide agar-gel electrophoresis for serum protein fractionation was performed at 4℃ using veronal buffer, pH 8.6 and ionic strength 0.05, with 54 volts and 2.8mA for 60 minutes. The fractionated slide was stained with 0.1% thiazine red. The results were as follows: 1) Increase of immune-globulin macroglobulin (IgM), alphaglobulin, and immune-globulin A (IgA) by 95.8%, 100%, 29.2% respectively was found in the serum from various thyroid diseases. 2) Thyroglobulin fraction was found to be increased in 50%, no change in 41.7%, and no line in 8.3% with all of the various goiter patients. On the other hand, 10 normal control group showed only 2 cases of increase, 5 cases of no change and 3 cases of no line. $quot;

한국형 출혈열에서의 혈류역동학적 연구

이문호,이정상,고창순,한지영 대한핵의학회 1974 핵의학 분자영상 Vol.8 No.1

한국형 출혈열 환자 38예룰 대상으로 방사성동위원소를 이용하여 각 병기에 따라 체계적으로 혈류역동학적 검사를 실시하여 다음과 같은 결론을 얻었다. 1) 혈장량은 핍뇨기와 이뇨기중 고혈압기에서는 증가되어 있었으나 이뇨기중 정상혈압기 이후부터는 정상으로 회복되었다. 2) 심박출계수는 핍뇨기에서는 증가되어 있었으나 이뇨기 이후부터는 정상이었다. 3) 전말초저항은 이뇨기중 고혈압기에서는 유의하게 증가되어 있었으며 정상혈압기 이후부터 계단적으로 감소하여 정상으로 회복되었다. 4) 신혈장류량은 핍뇨기, 이뇨기 및 회복기 초에는 유의하게 감소되어 있었으며 핍뇨기와 이뇨기초사이에는 유의한 차가 없었다. 회복기초에는 정상의 45%에 불과하였으나 발병 6개월후에는 정상과 차가 없었다. 5) 핍뇨기와 이뇨기중 고혈압기에서 $quot;$quot;상대적 과혈장증$quot;$quot;의 임상증후군을 나타낸 예들의 혈류역동학적 변화는 심박출량의 증가와 정상 혹은 약간 증가된 전말초저항이 특징적이었으며, 이는 유효맥공간(effective vascular space)의 감소로 상대적인 순환혈액량의 증가에 기인한 것이다. 이상의 성적으로 보아 한국형 출혈량의 심혈류역동학적 변화는 상대적 순환혈액량의 증가에 기인한 것이며 이뇨기 말에 정상으로 회복되고 신혈류역동학적 변화는 6개월 이후에는 정상으로 회복되었다. The author in an attempt to evaluate hemodynamic changes in the clinical stages of Korean hemorrhagic fever measured plasma volume, cardiac output and effective renal plasma flow utilizing radioisoto as during various phases of the disease. Cardiac output was measured by radiocardiography with external monitoring method using RIHSA. Effective renal plasma flow was obtained from blood clearance curve drawn by external monitoring after radiohippuran injection according to the method described by Razzak et al. The study was carried out in thirty-eight cases of Korean hemorrhagic fever and the following conclusions were obtained. 1) Plasma volume was increased in the patients during the oliguric and hypertensive-diuretic phases, while it was normal in the patients during the normotensive-diuretic phase. 2) Cardiac index was increased in the patients during the oliguric phase and was slightly increased in the patients at the hypertensive diuretic phase. It was normal in the other phases. 3) Total peripheral resistance was increased in the hypertensive patients during diuretic phase, while it was normal in the rest of phases. 4) Effective renal plasma flow was significantly reduced in the patients during the oliguric and diuretic phases as well as at one month after the oliguric onset. There was no significant difference between the oliguric and the early diuretic phases. Renal plasma flow in the group of patients at one month after the oliguric onset was about 45% of the normal, however, it returned to normal level at six months after the onset. 5) Clinical syndrome of relative hypervolemia was observed in some patients during the oliguric phase or hypertensive diuretic phase. Characteristic hemodynamic findings were high cardiac output and normal to relatively increased peripheral resistance these cases. Relatively increased circulating blood volumes due to decreased effective vasculat space was suggested for the mechanism of relative hypervolemia. 6) Cardiac hemodynamic alteration returned to normal during late stage of the diuretic phase, while renal hemodynamic changes were normalizd at six months after the onset. $quot;