상염색체우성 다낭신의 임상경과 및 합병증

이상주,이영모,이한규,최대은,박기현,이강욱,신영태 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Autosomal dominant polycystic kidney disease(ADPKD) is one of most common hereditary disorder. It is potentially fatal and the major mobilities are hypertension and renal failure. To elucidate clinical characteristics and outcomes of ADPKD, 67 ADPKD patients were analyzed retrospectively. The male to female ratio was 48 years for males and 42 years for females. The factors leading to the dignosis of ADPKD were flank or abdominal pain (46%), palpable abdominal mass (24%), incidental findings (18%), gross hematuria and headache. Urinalysis result showed hematuria (31%), proteinuria (19%), pyuria (18%). Among renal complications hypertension (67%) was the most common. Other complications were urolithiasis (16%) upper urinary tract infection (9%), cyst infection (7%). Azotemia was observed in 24% of cases. Echocardiography showed left ventricular hypertrophy in 24% and valvular regurgitation in 18% of cases, but there was no mital valve prolapse. Cerebrovascular events occurred in 6 cases (2 cases of intervertebral hemorrhage and 4 cases of cerebral infarction). Hipatic cyst were observed in 64% of cases. Eighteen cases culminated in end stage renal failure (ESRF) at an of 47. According to this study, the most common complications of ADPKD was hypertension (67%), ESRF (27%), and cerebrovascular event (9%). Hypertension was more frequently observed in increased creatinine group than normal.

사후분해 시체에 대한 법의학적 접근

최영식,이상용,김유훈,조갑래,이봉우,양경무,정낙은,서중석,이한영,이원태,강현욱 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2

Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.

간세포암과 하대정맥 막성폐쇄의 치료 후 호전된 백혈구파괴혈관염 1예

이준엽 ( Jun Yeob Lee1 ),이주원 ( Ju Won Lee1 ),이진욱 ( Jin Wook Lee ),박현준 ( Hyun Joon Park ),장국환 ( Gook Hwan Jang ),김다정 ( Da Jung Kim ),김선민 ( Sun Min Kim ),한병훈 ( Byung Hoon Han ),정규식 ( Gyoo Sik Jung ),김근태 ( 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.5

저자들은 하지 자색반과 고환 통증으로 내원한 알코올성 간경화증 환자에서 LCV의 원인 감별하는 과정에서 HCC와 하대정맥 막성폐쇄를 진단하고 이에 대한 치료 후 LCV의 호전된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Vasculitis is a heterogeneous group of diseases that destroy blood vessel walls by inflammation. Approximately half of vasculitis cases are idiopathic, but sometimes associated with genetic factors, medicines, chronic infection, autoimmune diseases, and malignancies. Although the mechanism remains unclear, vasculitis secondary to malignancy, also known as paraneoplastic vasculitis, has been reported. It is generally associated with hematologic malignancies rather than solid malignancies and commonly presents as leukocytoclastic vasculitis or polyarteritis nodosa. We experienced a case of leukocytoclastic vasculitis in a patient with hepatocellular carcinoma and membranous obstruction of the inferior vena cava. Here, we report this case with a brief review of literature. (J Rheum Dis 2015;22:322-326)

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

횡문근융해증과 급성 신부전 및 범발성 혈관내 응고장애를 동반한 열사병 1예

최대은,박수진,권오경,이한규,이영모,이상주,나기량,이강욱,신영태 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Heat stroke is a life-threatening illness characterized by an elevated core body temperature that rises above 40% and central nervous system dysfunctions that results in delirium, convulsions, or coma. Heat stroke is subdivided into two forms, classic and exertional. Since strenuous exercise is one of the major exacerbating and precipitating factors, the incidence of exertional heat stroke is high among young adult, especially military personnel undergoing military training. Exertional heat stroke commonly causes rhabdomyolysis, lactic acidosis, acute renal failure, shock and pulmonary edema. We report a case of heat stroke with rhabdomyolysis, acute renal failure, disseminated intravascular coagulopathy(DIC) after strenuous exercise. A 18 year old man was admitted to the hospital because of loss of consciousness. He was a wrestler and he had tried to lose 6kg in weight by jogging and strenuous exercise on that summer day with hot temperature. The development of this illness was favoured by much clothes inappropriate for that environmental condition with a purpose to enhance sweating, and by restricted intake of water and food. On admission, the blood pressure was 80/50mmHg, and body temperature was 39.4℃ with stuporous mentality. Laboratory finding were as follows : in complete blood cell count, hemoglobin was 16.7g/dL and platelet count was 158,000/ mm³. In blood chemistry, AST 1061U/L, ALT 201U/L, BUN 30mg/dL, Cr 2.2mg/dL, LDH 941IU/L, CK 696IU/L were resulted. In arterial blood gas analysis, pH 7.39, pCO₂ 30mmHg pO₂ 86mmHg, HCO₃ 18.4mEq/L, O₂ saturation 96.7% were resulted. In urinalysis, specific gravity 1.025, protein 3+, erythrocyte 2+ were resulted. In brain imaging study, brain CT finding was normal. After appropriate treatments with rapid cooling, hydration and supportive care, he improved with alert mental status. On 2nd hospital day, in laboratory result, thrombocytopenia and coagulopathy were appeared and renal insufficiency was aggravated. So he was treated with platelet concentrate and fresh frosen plasma for DIC, and enough hydration for appropriate urine volume preservation. After all, On 22nd hospital day, he fully recovered and discharged. Nowadays, with followed for some duration, he is wellbeing with no complications.

데이타베이스 시스템을 이용한 웹 자원 관리 엔진의 설계 및 구현

이명석,김진호,김상욱,유한양 강원대학교 정보통신연구소 1999 정보통신논문지 Vol.3 No.-

In this paper, we propose a web resource management engine based on general DBMSs. The web resources management engine manages the meta information describing the characteristics of resourves in a target web site. The engine extracts the meta information from HTML documents in the site and stores it into a predefined database called virtual schema. We use a general-purpose DBMS for maintaining the virtual schema. For design of the virtual schema, we model each element of HTML documents as a DBMS relation, and each attribute of an element as an attribute of its corresponding DBMS relation. We also model the link information among HTML documents as another relation. In order to merge the web and database having the virtual schema, we employ some additional tags in HTML documents, which were originally proposed in the INFORMIX WebDataBlade. Our web resource management engine has the following good features: (1) it supports dynamic changes of the web resources in a site by issuing update queries on the virtual schema, (2) it provides such searches that are based on structural characteristics of HTML documents since the virtual schema keeps the necessary information, (3) it provides the standard SQL interface for users to simply search and update the web resources, and finally, (4) it is portable to any DBMSs by just extending the gateway between the web and database since it only uses the common facilities supported by general-purpose DBMSs.

坡州郡 廣灘面에 있어서의 肺吸蟲症의 疫學的 推移

李駿商,鄭然郁,林漢鍾,朴永模 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.3

Paragonimiasis is a common trematodiasis of medical importance and one of public health problems in many areas of southern part of Korea. During the last sixty years, several surveys on the prevalence among the Korean population have been carried out by various investigators, although the general distribution and prevalence of paragonimiasis are not yet clearly determined. This study was undertaken to compare the status of human paragonimiasis in Kwang-Tan Myun, Pa Joo Gun by the use of intradermal screening test with Veronal buffered saline antigen. 1. In 1969, 27.9 per cent of the inhabitant examiners showed positive reaction, with sexual difference of 38.7 per cent in male and 8.3 per cent in female. 2. In 1977, 19.8 per cent of the inhabitant examiners showed positive reaction, with sexual difference of 31.9 per cent in male and 3.8 per cent in female. 3. In 1977, 1.9 per cent of the student examiners showed positive reaction. 4. In the inhabitant examiners, relarively higher positive rate was shown from the age group of 10 years in 1969, but it was shown from the age group of 40 years in 1977.

22q11.2 미세 결실 증후군 환아에서 내분비 기능 및 성장에 관한 연구

이종승,최진호,유한욱 대한소아내분비학회 2004 Annals of Pediatirc Endocrinology & Metabolism Vol.9 No.1

아말감 와동의 파절에 관한 2차원 유한요소법적 연구 Ⅰ : VARIATION OF THE WIDTH OF CAVITY 와동 폭의 변화

이정식,김한욱 大韓齒科保存學會 1995 Restorative Dentistry & Endodontics Vol.20 No.2

과학 교과와 연계된 통합 교육의 국내 연구 동향 분석

이효녕,권영륜,김성년,손성호,한욱신,홍성구,박병열,전재돈 이화여자대학교 교과교육연구소 2014 교과교육학연구 Vol.18 No.2

This study analyzed trends in domestic research over the last twelve years before and after the 2009 curriculum revision with respect to integrated science education. The data was reviewed and collected from masters theses, doctoral dissertations, and research articles published from 2001 to 2012. An analyzing framework was developed through literature reviews and content analysis of the previous studies. A total of 329 studies were selected and analyzed by year, type, content, and object of research. In addition, the method of organization of the subject, the elements of integration, and the method of integration among different disciplines were additionally analyzed to discover the trends in integrated teaching-learning programs. The results indicated that the number of domestic studies related to integrated science education increased from 2001 to 2012. The development and application of teaching-learning programs as a form of research, teaching and learning as a research topic, and elementary school students as research objects were conducted more often than other studies. According to an analysis of teaching-learning programs, the subject matter integrated most often with science was fine art, and a theme-based integration approach was applied to the majority of the forms of integrated education. It is therefore recommended that development of teaching and learning materials and teacher training programs in integrated science education will be needed to foster students’ integrated scientific literacy. 이 연구의 목적은 2009 개정 과학과 교육과정이 도입되기 전후 12년 동안 과학교과와 연계된 통합교육의 국내연구는 어떻게 이루어져 왔는지 알아보는 것이다. 이 연구문제를 위해 2001년부터 2012년까지 학술지에 게재된 논문과 학위 논문 329편을 대상으로 그 동향을 분석하였다. 과학교육 연구 측면에서의 연구동향을 알아보기 위해 이론적 배경을 통해 분석틀을 제작 하고 제작한 분석틀에 따라 연도별 연구 형태,연구 방법, 연구 내용, 연구 대상을 분석하였다. 또 분석 대상 논문 중 교수 · 학습 프로그램을 개발한 논문을 개발한 분석틀에 따라 어떤 교과가 과학교과와 통합이 이루어졌는지, 교과의 조직방식, 통합의 조직요소, 학문이 연결되는 방식이 어떠한지를 분석하였다. 연구의 결과 과학교과와 연계된 통합교육의 연구논문이 증가하였고, 연구 유형으로는 교수 · 학습 프로그램의 개발과 적용, 연구 주제는 교수 · 학습, 연구대상으로는 초등학생이 많았다. 지난 12년 동안 개발된 교수 · 학습 프로그램을 분석한 결과, 과학교과와통합을 가장 많이 한 교과는 미술이었고, 통합의 유형은 기여적 통합, 주제 중심 통합, 간학문적 통합이 가장 많았다. 본 연구의 결과를 바탕으로 학생들의 융합적인 소양의 배양을 위해 통합 과학 교육 교수학습 자료의 개발과 교사 연수프로그램의 개발 등을 제언하였다.