베타-아밀로이드 펩타이드로 유발된 신경세포사와 tau 인산화와의 연관성

김지형,홍혜남,이종환,황승준,박형섭,이흥식,김동호 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.4

파노라마방사선사진을 이용한 경상돌기에 관한 연구

황지영,황의환,이상래 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.2

Purpose : To find statistically based information about the natural variation in the length of the styloid process and to show the influence of the gender and age on the length of the styloid process. Materials and Methods : 1,300 panoramic radiographs were retrieved from inactive files at the Dental Hospital of Kyung Hee University. Measurements of the length of the styloid process were made directly on the radiographs from the inferior margin of the tympanic plate to the tip of the styloid process. Results : The mean length of 948 styloid processes was 25.2 mm±6.6. The median was 24.5 mm, and the interquartile range was 7 mm. The mean length was 25.7 mm for male and 24.6 mm for female. All percentile was greater for male than for female. The median is 25 mm for male and 24 mm for female. Conclusion : This study suggests that the difference of the styloid process length between genders was statistically significant and the length of styloid process was significant increased with age until 30 years.

홍화씨 열수 추출 분말을 이용한 우리 밀 라면의 제조

심지연,황은희,이일환,장혜순 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

The purpose of this study was to make ramyon from Korean cultured wheat by adding with hot water extract powder from safflower seed in order to add the value of it. The cooking quality, instrumental texture and sensory characteristics of ramyon were analyzed. The ramyons with 0.1%, 0.3%, 0.5%, and 0.7% of hot water extract powder(HEP) from safflower seed, control, and those with 3% and 5% of dried powder(DP) from safflower seed were compared. The yield of HEP was 7.8%. Lightness, redness, Max. weight, strength, hardness, adhesiveness, cohesiveness and springiness were measured. As the amounts of HEP and DP was increasing, ramyons smelled stronger and was getting harder and chewier, while became less transparent and had no difference in elasticity and adhesiveness. In overall acceptability, both control and ramyon with HEP had similar points. From three important factors, appearance, color and smell to make ramyon more acceptable, addition of 0.3~0.5% of hot water extract powder from safflower seed was found to be the best. However, further studies on smells are needed to make processed foodstuffs with safflower seed.

전자상거래 물류수송 및 CVO(Commerical Vehicle Operation)를 이용한 화물 위치추적 시스템 연구

정지문,황동환,최성 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

본 논문은 현재 발전하고 있는 전자상거래의 겉모습만을 보고 있는 사람들에게 그내부의 모습을 보여주는 한편, 물류수송의 문제점을 파악하여 그에따른 물류비용의 증가를 막아보자는데 있다. 전자상거래의 힘은 신속정확한 배달과 품질보증이다. 이에 따라 시간이 걸리는 배달일 경우에는 소비자의 기다림을 달래주는 위치 추적 정보 서비스가 필요하다. 종합물류 관리시스템의 하나인 CVO의 기술을 분석하고 화물위치 추적 시스템에 대하여 연구하였다. 특히 현재 우리나라의 쇼핑몰이나 기업의 상황을 분석하고, 전자 상거래의 배달, 운송에 관한 연구와 고찰로써 전자상거래 시대에 있어서 모든 기업들의 발전방안을 연구하였다.

한국과 베트남 사람들의 정서 체험

김지현,판후옹,황석현,민경환 서울大學校 社會科學大學 心理科學硏究所 1997 心理科學 Vol.6 No.2

본 연구는 한국과 베트남 사람들의 정서 체험에 관한 연구이다. 정서의 보편성과 문화적 변산성에 관한 이론적 연구를 위한 자료를 수집하기 위한 목적으로, 사람들이 다양한 정서 상태들을 경험할 때 느끼는 생리적 반응, 언어적 표현, 행동 반응, 주관적 느낌 및 그러한 정서를 유발하는 상황에 초점을 두어 베트남 사람들과 한국 사람들의 정서 체험 내용의 공통점과 차이점을 알아보았다. 베트남에서는 국립 베트남 대학교와 국립 호치민 대학교에 재학중인 215명이 본 연구에 참여하였고, 한국에서는 60명의 국립 서울대학교 학부생들이 참가하였다. 기쁨, 슬픔, 공포, 분노의 네 가지 정서가 정서 체험에 관한 자기-보고 질문지를 사용하여 연구되었다. 결과는 다음과 같다. 첫째, 특정한 정서를 유발하는 원인이 되는 선행 사건들의 보편성을 밝혔다. 다음으로, 다양한 정서를 체험할 때 나타나는 반응들의 패턴에 있어서 문화간 변산성이 나타남을 확인하였다. 세 번째로 여성과 남성의 정서 체험의 내용에서 몇 가지 흥미로운 차이점들이 발견되었다. 마지막으로 후속 연구를 위한 시사점들이 논의되었다. The emotional experiences of Koreans and Vietnamese were studied. In order to collect the data for the purpose of conducting a theoretical study on universality of emotions and cultural variations, the similarities and differences in the various aspects of emotional experiences of Koreans and Vietnamese were examined, which included physiological responses, verbal expressions, behavioral patterns, subjective feelings, and the antecedent events that were the causes of the emotional experiences. 215 Vietnamese undergraduates from Vietnam National University and Ho Chi Min University and 60 Korean undergraduates from Seoul National University participated in this study. Using a self-report form, emotional experiences of joy, sadness, fear, and anger were examined. As the result, universality of antecedent events for specific emotions was confirmed. Cultural variations in the emotional response patterns were confirmed as well. Finally, some interesting sex differences in emotional experiences were found. Implications and suggestions for the future study were discussed.

lacZ 유전자를 이용한 Bacillus subtilis 유전체에서의 promoter 부위 탐색

이하규,황혜진,김지환 가톨릭대학교 자연과학연구소 2007 자연과학논문집 Vol.28 No.-

Bacillus subtilis는 GRAS균주로서 최근에 유전공학 식품과 약품 재료로 많이 이용된다. 본 연구에서는 B. subtilis에서의 expression system을 만들기 위해 B. subtilis의 genomic DNA에서 promoter 서열을 검색하였다. lacZ 유전자를 가지는 상업용 TA cloning vector에서 이 promoter를 제거하고 B. subtilis의 DNA 단편으로 이 부위를 대체했다. 재조합 plasmid library를 DH5a에 형질전환 시켰다. 형질전환 후 X-gal 분석을 통하여 blue colony를 골라내어 삽입된 단편의 서열을 분석하였다. Plasmid 서열분석을 통해 promoter로 추정되는 4개의 서열을 얻었다. IPTG test를 통해 이 서열들의 유도성 여부를 확인했다. On-line software program인 BPROM(http://www.softberrt.com)을 이용하여 추정된 4개의 서열들이 promoter 특이 보존성 서열을 가지고 있음을 확인했다. 이러한 서열들은 B. subtilis의 promoter로서 가능성을 가짐에 따라, 향후 유전자 발현 실험을 통해 promoter 활성을 검증 하는 등의 연구가 수행되어야 할 것이다. Bacillus subtilis is one of the GRAS bacteria, and it's application for production of genetic engineered food and drug material is increasing in recent days. In this study, for the construction of expression system in B. subtilis, we screened promoter sequences in the bacterial genomic DNA. Using the commercial TA cloning vector containing lacZ gene, we removed its promoter and replaced it with Bacillus DNA fragments. This recombinant plasmid library was transferred to DH5a strain. Based on the X-gal assay after the transformation, blue colonies were selected and their plasmids were sequenced in the replaced region. 4 sequences were recruited as candidate promoters. We confirmed the induction of these sequences by IPTG test. On-line software program, BPROM, was showed all of these sequences have promoter-specific conserved sequences. We suggest these sequences are probable promoter of B. subtilis, and it should be further studied for applicational development.

Ka-밴드 도파관 슬롯 배열 안테나 설계와 제작

具然健,黃志煥 홍익대학교 산업기술연구소 2002 産業技術 Vol.12 No.-

This paper presents a waveguide slot 16x16 array antenna with diaphragm for 37.5~38.5 GHz frequency band. At first, the radiation characteristics of longitudinal slots on a broadside of a waveguide have been examined. Diaphragms are used to control the impedance and to minimize the return loss of the structure. A 20 dB Chebyshev array of 16 waveguide slots has been designed by optimizing the positions and sizes of the diaphragms and the slots. Then, a serial feeding system with π-junction power dividers has also designed to get a 20 dB Chebyshev power distribution. We used the HFSS for full-wave analysis and the MW Office for equivalent circuit simulations. The 16x16 slot array antenna, which was designed for a Fixed Wireless Access System at 38 GHz frequency, gives an antenna gain higher than 30 dBi. A slot array antenna was manufactured using a computer controlled milling technique, and measured for the return loss and the antenna pattern.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

3차 의료기관에 입원한 노숙환자에서 감염질환의 유병율

함세운,남기석,노혜진,홍경득,황래석,방지환,신형식 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

목적 : 3차 의료기관에서 입원치료를 받았던 노숙자를 대상으로 감염성 질환의 유병율을 알아보고자 하였다. 재료 및 방법 : 2002년 1월부터 2004년 8월 사이에 국립의료원에서 입원 치료를 받았던 269명의 노숙자 환자들을 대상으로 의무기록을 조사하였다. 결과 : 연구 기간동안 입원치료를 받은 총 269명의 노숙자 환자 중 남자가 249명(92.9%), 여자가 19명(7.1%)이었다. 감염질환의 유병율은 B형 간염이 228명 중 15명(6.6%), C형 간염 113명 중 8명(7.1%), 결핵은 269명중 19명(7.1%), VDRL 양성인 경우는 234명 중 25명(10.7%), 항사람면역결핍바이러스항체 양성은 130명중 2명(1.5%)이었다. B형 간염표면항원에 대한 항체 형성자는 118명(51.7%), 항체 미형성자는 95명(41.7%)이었다. 결핵으로 진단된 19명 중 객담도말 및 배양검사와 조직검사로 확인된 경우가 14명, 균음성이나 임상적으로 의심되는 경우가 5명이었다. 간질환 및 관련된 합병증으로 입원한 환자 28명 중 B형 및 C형 간염바이러스에 관련된 경우는 5명(17.9%)에불과하였고 결핵은 19명중 13명(68.4%)이 폐결핵 및 림프절종대의 증상으로 입원치료를 받았다. 복합 감염의 경우는 총 9명이었는데 후천면역결핍증후군 환자였던 2명중 1명이 결핵에 이환되어 있으면서 VDRL 양성소견을 보였고 다른 1명이 HIV와 결핵의 동시감염이었다. 결론 : 노숙자 입원환자에서 결핵, C형 간염 및 매독의 유병율이 일반 인구에 비해 높았다. 노숙자환자를 담당하는 의료인력를 보호하고 환자의 감염질환 유무를 파악하기 위해 적절한 선별검사가 필요하며 감염질환의 확산을 방지하기 위한 정부의 적극적인 대책이 필요하다. Background : Despite the expected high prevalence of several infectious diseases among the homeless, a majority of them have not received screening test and early treatment. Materials and Methods : The subjects of this study were 269 homeless patients who had been hospitalized in the National Medical Center (Korea) between January 2002 and August 2004. Their medical histories and records were reviewed to analyze the prevalence and clinical characteristics of hepatitis B and C, syphilis, tuberculosis and HIV infection among them. Results : The entire 269 homeless patients being hospitalized during the period of this study consist of 249 male patients and 19 female patients. For the prevalence of infectious diseases, HBV was seen in 15 of 228 patients (6.6%); HCV in 8 of 113 patients (7.1%); VDRL positive in 25 of 234 patients (10.7 %); HIV antibody positive in 2 of 130 (1.5%); and tuberculosis in 19 of 269 (7.1%). The number of patients who had the antibody to hepatitis B was 118 (51.7%). Of 28 patients hospitalized with the chief complaints of liver diseases and/or their complications, the number of cases infected with hepatitis B and C viruses was only 5 (17.9%). On the other hand, for patients with tuberculosis, 13 of 19 cases (68.4%) were hospitalized with the chief complaints associated with symptoms of pulmonary tuberculosis or enlarged lymph nodes. The number of patients with multiple infectious diseases was 9 in total. Conclusion : As expected, the prevalence of some infectious diseases were higher among the homeless inpatients, than non-homeless population. Proper screening tests in order to determine the presence of any infectious diseases among the patients and protect involved medical staff are necessary. Further, the government should take proactive measures to prevent the spread of infectious diseases in the aspect of public health.

개의 흉추 및 요추에서 배측 추궁절제술 1례

김명철,이재일,이수진,김종만,황학균,서지민,이영원,김덕환,신상태 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In dorsal laminectomy for the surgical treatment of thoracolumbar disc disease in dog, the bur could slip into the vertebral canal. For the decrease of this probability of danger, osteotome was used with instruments such as bur and rongeur in dorsal laminectomy. At thoracic vertebrae (T10-T11) and lumbar vertebrae (L5-L6) area, dorsal laminectomys were performed in a dog. In observation for 3 months after surgery, the dog revealed healthy physical condition. For the confirmation of healing condition at 3 months after dorsal laminectomy, two surgical sites were exposed by incision. Excellent healing response was observed with no adhesion and fibrosis in the vertebral canal.