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신진우,조우승,조성빈,김재훈,정지은,사예지,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2
As modern people's interest in health grows, wearable healthcare-related technologies that can collect biometric information and receive health-related services regardless of time and place are developing. This paper proposes the healthcare system based on voice recognition function. Unlike conventional wearable healthcare systems, the proposed system provides real-time telemedicine and diagnosis and the direct connection with doctors is possible through it. And almost all functions of the application in it are operated with voice commands to lower user access barriers. Because it deals with personal information including medical information, encryption algorithms have been applied between all data movements. Finally, the healthcare system proposed in this paper is expected to increase convenience in health care and reduce the medical gap.
퍼지제어기를 이용한 분산 Multi Vehicle의 Color인식을 통한 물체이송 연구
우지민,경제문,최승민,김훈모 기계기술연구소 2000 성균관대학교 논문집 기계기술편 Vol.2 No.1
In this paper, we present a collaboration method for material delivery with distributed vehicle agents system. Generally used AGV(Autonomous Guided Vehicle) systems in FA need extraordinary facilities like guidepaths, landmarks and have lots of limitation for applying in various environments and in case of controlling multi vehicles including different types is increasing nowadays for automation of materials between vehicles including different types is increasing nowadays for automation of material of material flow. Thus to compensate and improve functions of AGV, it is important to endow vehicles with intelligence to recognize environments, goods and determine goal point to approach. In this study we propose interaction method between hetero-type vehicles and fuzzy logic controller for sensor based path planning method and material identifying method by recognizing color. For the purpose of carrying materials to the goal, instead of intricate vision system, simple color sensor is used to search for material, and recognize its color to determine goal point to transfer it to. The ability for proposed method will be demonstrated by computer simulation and experiment.
소장내 위석에 의한 장폐쇄증으로 발생한 급성신부전 1례
김승민,남지형,김준섭,이용국,최재혁,강혁주,탁우택,이정호,정호근 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1
Gastric bezoars are concretions or hard masses of foreign matter found in the gastrointestinal tract. It may induce many complications including intestinal obstruction. No report has been proposed on a case of prerenal ARF induced by intestinal obstruction by small-bowel bezoar. Therefore, we report a case of the patient with ARF associated with small-bowel bezoar, who initially visited with the symptoms of nausea and frequent vomiting. 위석(bezoar)은 여러 가지 이물 및 내재성물질이 위장관내에서 혼합되어 응고물을 형성한 것을 말하며, 가장 흔한 형태의 합병증으로 장폐쇄증이 올 수 있으나, 그로 인하여 신부전의 양상으로 나타나는 경우는 흔하지 않다. 이에 저자들은 내원 당시의 병력 및 이학적 검사만으로 장폐색의 원인이 위석임을 의심할 수 없었던 비전형적인 소견을 보인 소장내의 위석에 의한 장폐쇄증과 이로 인해 발생한 급성신부전의 예를 경험하였기에 이에 보고하는 바이다.
김찬우,이동건,강승훈,조지현,이수진,조동환,김정기 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.2
Objectives : Risperidone and olanzapine, which are atypical antipsychotics. are widely used in the treatment of schizophrenia as the 1st line drug, proving their effectiveness for both positive and negative symptoms. They also have many advantages even from the side effects. However, they show differences with the chemical structure and pharmacokinetics and they work differently to receptors. Researchers have studied the effect and side effect during the acute phase of schizophrenia as an open prospective study. Methods : Forty subjects with DSM-IV schizophrenia or schizoaffective patients including 1) 1st onset schizophrenia patient, 2) patient who has been treated by the prior antipsychotics and not improved or even worse to be admitted again, were assigned to receive risperidone or olanzapine for 6 weeks. Psychopathology, adverse effect. weight change, fasting serum glucose, and drug cost were compared within and across groups. Results : After 6 weeks later both treatment groups showed the significant decrease in PANSS positive, general psychopathology and total score while they did not show any significant difference between two groups. Risperidone group, however. showed the significant decrease in PANS negative score, which olanzapine group did not. In terms of adverse effect risperidone group showed more extrapyramidal symptom than olanzapine group. Body weight rised significantly after Gweeks, but no significant difference between two treatment groups. There were no significant indrease of fasting serum glucose level. Conclusions : Risperidone and olanzapine are effective drugs which can be used during the acute phase of schizophrenia. Risperidone is expected to shorten the admission day and remission of the symptom of acute phase, mile olarizapine is more advantage in a neurologic side effect than rispendone.
딜티아젬 함유 코아 펠렛으로부터 약물의 용출에 미치는 폴록사머 함량의 영향
이승우,감성훈,홍지웅,최기송,박은석,지상철 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.4
In order to evaluate the effect of poloxamer 407 content on the dissolution profiles of pellets, diltiazem HCl (DTL) core pellets were prepared with poloxamer 407 (50∼90% w/w, with lactose as filler) using an extruder and a spheronizer. Any possible interaction between the drug and excipients was evaluated using DSC, IR and TLC. Dissolution tests were performed using USP basket method. In addition, scanning electron micrograph was performed to examine the surface roughness and cross sections. The release of DTL from the core pellets was decreased with increasing poloxamer 407 content. Cracks appeared on the surface of the core pellets with increasing the poloxamer 407 content, which may play a role on the retardation of the release of DTL from core pellets. There was no any significant interaction between the drug and excipients employed to prepare the core pellets.
외상성 뇌손상 환자의 지능 장애와 K-WAIS 소검사내 분산도
오상우,김지영,노승호 圓光大學校 醫科大學 神經精神科學敎室 1997 圓光精神醫學 Vol.13 No.2
본 연구는 외상성 뇌손상 환자의 병전 지능을 추정하여, 추정된 지능을 현재 지능과 비교하고, K-WAIS 소검사내 분산도 분석을 시행하여 인지 기능의 효율성을 평가하고자 하였다. 연구 결과, 외상성 뇌손상 환자 집단은 정신분열증 집단이나 기타 임상 집단의 환자들에 비해 지능이 유의하게 저하되어 있었다. 그러나 소검사내 분산도 분석에서는 외상성 뇌손상 환자 집단이 다른 두 집단보다 인지적 효율성이 더 높았다. In this study, premorbid IQ in patients with traumatic brain injury were estimated and compared with measured IQ, and examined efficiency of cognitive function through K-WAIS intrasubtest scatter analysis. These results suggested that traumatic brain injury patient's IQ were significantly lower than those of the schizophrenia and other psychiatric patients. But traumatic brain injury patient's cognitive efficiency were higher than those of the schizophrenia and other psychiatric patients.
박지미,승현우,박미영 서울여자대학교 2010 정보기술논문지 Vol.8 No.-
The field of software engineering has been doing a new research to find out a desirable security system with its established study because the significance of information security is recently getting bigger and bigger in modern technology. As a result, a number of challenges are being attempted to devise a new method which is able to evaluate the security degree of software, like reliability estimation model that has been the criterion of software to decide whether it is trustworthy or not. In this paper, the reliability growth model, which has been previously designed to estimate the reliability of software, will be discussed. In addition, the uppermost limit and the application plan of the reliability growth model falls within the ambit of this research when this model is being applied to the reliability estimation model.
인체 간 Microsome에서의 우슬 추출물의 Cytochrome P450 약물 대사효소에 대한 억제작용
김경아,이지숙,박히준,김진우,김창주,심인섭,한승무,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-
Objective : Achyranthes bidentata radix (Usul) has been used as anti-arthritic, antiallergic, antidiuretic and so on Recently extracts of Achyranthes bidentata radix have shown anti-inflammatory and cancer preventive effects in vitro and in vivo. Methods : We therefore evaluated the inhibitory potential of ehtanol extracts of Achyranthes bidentata radix on cytochrome P450(CYP) isoforms-catalyzecd reactions, which relate to causes of cancer and inflammation, including CYP1A2, CYP2C9, CYP2C19, CYP2E1, CYP2D6, CYP2C8, and CYP3A4, using human liver microsomal preparations. Results : The extracts showed weak or negligible inhibitory effects on CYP2C9-catalyzed (S)-warfarin 7-hydroxylation, CYP2C19-catalyzed S-mephenytoin 4-hydroxylation, and CYP2D6-catalyzed dextromethorphan O-demethylation with each IC50 over 1750 g/㎖, respectively. However, it showed relatively significant inhibitory effect on CYP1A2-catalyzed phenacetin O-deethylation and CYP2E1-catalyzed chloizoxazone 6-hydroxylation with IC50s of 970.5 g/㎖ and 821.4 g/㎖, respectively. Conclusions : These results suggest that extracts of Achyranthes bidentata radix have inhibitory effects on CYP-catalyzed reactions, expeciallyCYP1A2 and CYP2E1, in human liver microsomes. These effects appear to relate to anti-inflammatory and cancer prevention following decrease of reactive oxygen species formed by CYP, especially CYP1A2 and CYP2E1, by Achyranthes bidentata radix. However, further evaluation is necessary to demonstrate and to confirm its effects in human.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.